All Stories

  1. Activation of Wnt/β-catenin signaling in abdominal aortic aneurysm: A potential therapeutic opportunity?

    Article • Genes & Diseases, May 2023, Tsinghua University Press

    Jose Martinez Gonzalez, Dr Cristina Rodriguez

  2. Endothelial NOD1 directs myeloid cell recruitment in atherosclerosis through VCAM-1

    Article • The FASEB Journal, November 2018, Federation of American Societies For Experimental Biology (FASEB)

    Dr Paloma Martin-Sanz, Dr Cristina Rodriguez, Silvia Gonzalez-Ramos, Miguel Angel Lasuncion

  3. Lysyl oxidase (LOX) limits VSMC proliferation and neointimal thickening through its extracellular enzymatic activity

    Article • Scientific Reports, September 2018, Springer Science + Business Media

    Dr Cristina Rodriguez

  4. The nuclear receptor NOR-1 modulates redox homeostasis in human vascular smooth muscle cells

    Article • Journal of Molecular and Cellular Cardiology, September 2018, Elsevier

    Dr Cristina Rodriguez

  5. Inhibition of enzymes involved in collagen cross-linking reduces vascular smooth muscle cell calcification

    Article • The FASEB Journal, August 2018, Federation of American Societies For Experimental Biology (FASEB)

    Dr Cristina Rodriguez

  6. MT4-MMP deficiency increases patrolling monocyte recruitment to early lesions and accelerates atherosclerosis

    Article • Nature Communications, March 2018, Springer Science + Business Media

    Dr Cristina Rodriguez

  7. Mecanismos de envejecimiento vascular: ¿Qué podemos aprender del síndrome de progeria de Hutchinson-Gilford?

    Article • Clínica e Investigación en Arteriosclerosis, March 2018, Elsevier

    Dr Cristina Rodriguez

  8. Circulating CCL20 as a New Biomarker of Abdominal Aortic Aneurysm

    Article • Scientific Reports, December 2017, Nature

    Dr Cristina Rodriguez

  9. Lysyl Oxidase Induces Vascular Oxidative Stress and Contributes to Arterial Stiffness and Abnormal Elastin Structure in Hypertension: Role of p38MAPK

    Article • Antioxidants & Redox Signaling, September 2017, Mary Ann Liebert Inc

    Jose Martinez Gonzalez, Dr Cristina Rodriguez

  10. La sobreexpresión vascular de la lisil oxidasa altera la estructura de la matriz extracelular e induce estrés oxidativo

    Article • Clínica e Investigación en Arteriosclerosis, July 2017, Elsevier

    Jose Martinez Gonzalez, Dr Cristina Rodriguez

  11. The nuclear receptor NOR-1 regulates vitronectin in human vascular smooth muscle cells

    Article • The FASEB Journal, June 2017, Federation of American Societies For Experimental Biology (FASEB)

    Dr Cristina Rodriguez, Jose Martinez Gonzalez

  12. Lysyl oxidase overexpression accelerates cardiac remodeling and aggravates angiotensin II–induced hypertrophy

    Article • The FASEB Journal, May 2017, Federation of American Societies For Experimental Biology (FASEB)

    David Gracia-Dorado, Dr Antonio Rodriguez-Sinovas, Dr Cristina Rodriguez, Jose Martinez Gonzalez

  13. La inflamación inhibe la expresión vascular de la fibulina-5: implicación del factor de transcripción SOX9

    Article • Clínica e Investigación en Arteriosclerosis, November 2016, Elsevier

    Jose Martinez Gonzalez, Dr Cristina Rodriguez

  14. NOR-1/NR4A3 regulates the cellular inhibitor of apoptosis 2 (cIAP2) in vascular cells: role in the survival response to hypoxic stress

    Article • Scientific Reports, September 2016, Nature

    Jose Martinez Gonzalez, Dr Cristina Rodriguez

  15. Nestin+ cells direct inflammatory cell migration in atherosclerosis

    Article • Nature Communications, September 2016, Nature

    Jose Martinez Gonzalez, Dr Cristina Rodriguez

  16. Endothelial Jag1-RBPJ signalling promotes inflammatory leucocyte recruitment and atherosclerosis

    Article • Cardiovascular Research, August 2016, European Society of Cardiology

    Dr Cristina Rodriguez

  17. The nuclear receptor NOR-1 regulates the small muscle protein, X-linked (SMPX) and myotube differentiation

    Article • Scientific Reports, May 2016, Nature

    Jose Martinez Gonzalez, Dr Cristina Rodriguez

  18. Down-regulation of Fibulin-5 is associated with aortic dilation: role of inflammation and epigenetics

    Article • Cardiovascular Research, April 2016, European Society of Cardiology

    Dr Cristina Rodriguez, Jose Martinez Gonzalez

  19. Induction of histone deacetylases (HDACs) in human abdominal aortic aneurysm: therapeutic potential of HDAC inhibitors

    Article • Disease Models & Mechanisms, March 2016, The Company of Biologists

    Jose Martinez Gonzalez, Dr Cristina Rodriguez

  20. The lysyl oxidase inhibitor (β-aminopropionitrile) reduces leptin profibrotic effects and ameliorates cardiovascular remodeling in diet-induced obesity in rats

    Article • Journal of Molecular and Cellular Cardiology, March 2016, Elsevier

    Jose Martinez Gonzalez, Dr Cristina Rodriguez

  21. Hu antigen R is required for NOX-1 but not NOX-4 regulation by inflammatory stimuli in vascular smooth muscle cells

    Article • Journal of Hypertension, February 2016, Wolters Kluwer Health

    Jose Martinez Gonzalez, Dr Cristina Rodriguez

  22. miR-17 and -20a Target the Neuron-Derived Orphan Receptor-1 (NOR-1) in Vascular Endothelial Cells

    Article • PLoS ONE, November 2015, PLOS

    Jose Martinez Gonzalez, Dr Cristina Rodriguez

  23. NR4A receptors up-regulate the antiproteinase alpha-2 macroglobulin (A2M) and modulate MMP-2 and MMP-9 in vascular smooth muscle cells

    Article • Thrombosis and Haemostasis, November 2015, Schattauer GmbH

    Jose Martinez Gonzalez, Dr Cristina Rodriguez

  24. Expression and Cellular Localization of 15-Hydroxy-Prostaglandin-Dehydrogenase in Abdominal Aortic Aneurysm

    Article • PLoS ONE, August 2015, PLOS

    Jose Martinez Gonzalez, Dr Cristina Rodriguez

  25. miR-146a targets Fos expression in human cardiac cells

    Article • Disease Models & Mechanisms, June 2015, The Company of Biologists

    Jose Martinez Gonzalez, Dr Cristina Rodriguez

  26. CALU polymorphism A29809G affects calumenin availability involving vascular calcification

    Article • Journal of Molecular and Cellular Cardiology, May 2015, Elsevier

    Jose Martinez Gonzalez, Dr Cristina Rodriguez

  27. The lysyl oxidase inhibitor  -aminopropionitrile reduces body weight gain and improves the metabolic profile in diet-induced obesity in rats

    Article • Disease Models & Mechanisms, April 2015, The Company of Biologists

    Jose Martinez Gonzalez, Dr Cristina Rodriguez

  28. HuR mediates the synergistic effects of angiotensin II and IL-1β on vascular COX-2 expression and cell migration

    Article • British Journal of Pharmacology, March 2015, Wiley

    Jose Martinez Gonzalez, Dr Cristina Rodriguez

  29. NOR-1 modulates the inflammatory response of vascular smooth muscle cells by preventing NFκB activation

    Article • Journal of Molecular and Cellular Cardiology, March 2015, Elsevier

    Jose Martinez Gonzalez, Dr Cristina Rodriguez

  30. Ageing is associated with deterioration of calcium homeostasis in isolated human right atrial myocytes

    Article • Cardiovascular Research, February 2015, European Society of Cardiology

    Jose Martinez Gonzalez, Dr Cristina Rodriguez

  31. Endothelial Krüppel-Like Factor 4 Modulates Pulmonary Arterial Hypertension

    Article • American Journal of Respiratory Cell and Molecular Biology, March 2014, American Thoracic Society

    Jose Martinez Gonzalez, Dr Cristina Rodriguez

  32. El receptor nuclear NOR-1 regula la activación de las células vasculares y el remodelado vascular en respuesta a estrés hemodinámico

    Article • Clínica e Investigación en Arteriosclerosis, March 2014, Elsevier

    Jose Martinez Gonzalez, Dr Cristina Rodriguez

  33. Lysyl oxidase (LOX) in vascular remodelling

    Article • Thrombosis and Haemostasis, January 2014, Schattauer GmbH

    Jose Martinez Gonzalez, Dr Cristina Rodriguez

  34. Microvascular COX-2/mPGES-1/EP-4 axis in human abdominal aortic aneurysm

    Article • Journal of Lipid Research, October 2013, American Society for Biochemistry & Molecular Biology (ASBMB)

    Jose Martinez Gonzalez, Dr Cristina Rodriguez

  35. A major role for RCAN1 in atherosclerosis progression

    Article • EMBO Molecular Medicine, October 2013, EMBO

    Jose Martinez Gonzalez, Dr Cristina Rodriguez

  36. Targeting p35/Cdk5 Signalling via CIP-Peptide Promotes Angiogenesis in Hypoxia

    Article • PLoS ONE, September 2013, PLOS

    Jose Martinez Gonzalez, Dr Cristina Rodriguez

  37. Left and Right Ventricle Late Remodeling Following Myocardial Infarction in Rats

    Article • PLoS ONE, May 2013, PLOS

    Jose Martinez Gonzalez, Dr Cristina Rodriguez

  38. Inactivation of Nuclear Factor-Y Inhibits Vascular Smooth Muscle Cell Proliferation and Neointima Formation

    Article • Arteriosclerosis Thrombosis and Vascular Biology, February 2013, Wolters Kluwer Health

    Jose Martinez Gonzalez, Dr Cristina Rodriguez

  39. Over-expression of Neuron-derived Orphan Receptor-1 (NOR-1) exacerbates neointimal hyperplasia after vascular injury

    Article • Human Molecular Genetics, February 2013, Oxford University Press (OUP)

    Jose Martinez Gonzalez, Dr Cristina Rodriguez

  40. Synergistic Effect of Thrombin and CD40 Ligand on Endothelial Matrix Metalloproteinase-10 Expression and Microparticle Generation In Vitro and In Vivo

    Article • Arteriosclerosis Thrombosis and Vascular Biology, April 2012, Wolters Kluwer Health

    Jose A. Rodriguez, Jose Martinez Gonzalez, Dr Cristina Rodriguez

  41. Plasma profiling by a protein array approach identifies IGFBP-1 as a novel biomarker of abdominal aortic aneurysm

    Article • Atherosclerosis, April 2012, Elsevier

    Jose Martinez Gonzalez, Dr Cristina Rodriguez

  42. Deficient p27 Phosphorylation at Serine 10 Increases Macrophage Foam Cell Formation and Aggravates Atherosclerosis Through a Proliferation-Independent Mechanism

    Article • Arteriosclerosis Thrombosis and Vascular Biology, September 2011, Wolters Kluwer Health

    Dr Antonio Diez-Juan, Jose Martinez Gonzalez, Dr Cristina Rodriguez

  43. Type II interleukin-1 receptor expression is reduced in monocytes/macrophages and atherosclerotic lesions

    Article • Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, September 2011, Elsevier

    Jose Martinez Gonzalez, Dr Cristina Rodriguez

  44. CCL20 Is Increased in Hypercholesterolemic Subjects and Is Upregulated By LDL in Vascular Smooth Muscle Cells: Role of NF- B

    Article • Arteriosclerosis Thrombosis and Vascular Biology, August 2011, Wolters Kluwer Health

    Jose Martinez Gonzalez, Dr Cristina Rodriguez

  45. HIF-1-mediated up-regulation of cardiotrophin-1 is involved in the survival response of cardiomyocytes to hypoxia

    Article • Cardiovascular Research, July 2011, European Society of Cardiology

    Jose Martinez Gonzalez, Dr Cristina Rodriguez

  46. Regulación de la expresión génica por la lisil oxidasa (LOX): modulación de la α2-macroglobulina en células endoteliales

    Article • Clínica e Investigación en Arteriosclerosis, July 2011, Elsevier

    Dr Cristina Rodriguez

  47. Angiotensin II differentially modulates cyclooxygenase-2, microsomal prostaglandin E2 synthase-1 and prostaglandin I2 synthase expression in adventitial fibroblasts exposed to inflammatory stimuli

    Article • Journal of Hypertension, March 2011, Wolters Kluwer Health

    Jose Martinez Gonzalez, Dr Cristina Rodriguez

  48. Hypoxia upregulates PGI-synthase and increases PGI2release in human vascular cells exposed to inflammatory stimuli

    Article • Journal of Lipid Research, February 2011, American Society for Biochemistry & Molecular Biology (ASBMB)

    Jose Martinez Gonzalez, Dr Cristina Rodriguez

  49. Fibulin-5 Is Up-regulated by Hypoxia in Endothelial Cells through a Hypoxia-inducible Factor-1 (HIF-1α)-dependent Mechanism

    Article • Journal of Biological Chemistry, December 2010, American Society for Biochemistry & Molecular Biology (ASBMB)

    Jose Martinez Gonzalez, Dr Cristina Rodriguez

  50. New challenges for a second-generation low-molecular-weight heparin: focus on bemiparin

    Article • Expert Review of Cardiovascular Therapy, May 2010, Taylor & Francis

    Jose Martinez Gonzalez, Dr Cristina Rodriguez

  51. Trans-10 cis-12-CLA dysregulate lipid and glucose metabolism and induce hepatic NR4A receptors

    Article • Frontiers in Bioscience, January 2010, Frontiers in Bioscience

    Jose Martinez Gonzalez, Dr Cristina Rodriguez

  52. Matrix Metalloproteinase-10 Is Upregulated by Thrombin in Endothelial Cells and Increased in Patients With Enhanced Thrombin Generation

    Article • Arteriosclerosis Thrombosis and Vascular Biology, September 2009, Wolters Kluwer Health

    Jose A. Rodriguez, Jose Martinez Gonzalez, Dr Cristina Rodriguez

  53. The Hypoxia-Inducible Factor 1/NOR-1 Axis Regulates the Survival Response of Endothelial Cells to Hypoxia

    Article • Molecular and Cellular Biology, August 2009, ASM Journals

    Jose Martinez Gonzalez, Dr Cristina Rodriguez

  54. Statins normalize vascular lysyl oxidase down-regulation induced by proatherogenic risk factors

    Article • Cardiovascular Research, April 2009, European Society of Cardiology

    Jose Martinez Gonzalez, Dr Cristina Rodriguez

  55. p38 MAPK contributes to angiotensin II-induced COX-2 expression in aortic fibroblasts from normotensive and hypertensive rats

    Article • Journal of Hypertension, January 2009, Wolters Kluwer Health

    Jose Martinez Gonzalez, Dr Cristina Rodriguez

  56. Modulation of Endothelium and Endothelial Progenitor Cell Function by Low-Density Lipoproteins: Implication for Vascular Repair, Angiogenesis and Vasculogenesis

    Article • Pathobiology, January 2009, Karger Publishers

    Jose Martinez Gonzalez, Dr Cristina Rodriguez

  57. Bemiparin: second-generation, low-molecular-weight heparin for treatment and prophylaxis of venous thromboembolism

    Article • Expert Review of Cardiovascular Therapy, July 2008, Taylor & Francis

    Jose Martinez Gonzalez, Dr Cristina Rodriguez

  58. Prostacyclin induction by high-density lipoprotein (HDL) in vascular smooth muscle cells depends on sphingosine 1-phosphate receptors: Effect of simvastatin

    Article • Thrombosis and Haemostasis, June 2008, Schattauer GmbH

    Professor Lina Badimon, Jose Martinez Gonzalez, Dr Cristina Rodriguez

  59. Retinoic acid induces PGI synthase expression in human endothelial cells

    Article • Journal of Lipid Research, May 2008, American Society for Biochemistry & Molecular Biology (ASBMB)

    Jose Martinez Gonzalez, Dr Cristina Rodriguez

  60. Regulation of lysyl oxidase in vascular cells: lysyl oxidase as a new player in cardiovascular diseases

    Article • Cardiovascular Research, March 2008, European Society of Cardiology

    Jose Martinez Gonzalez, Dr Cristina Rodriguez

  61. Lysyl oxidase (LOX) down-regulation by TNFα: A new mechanism underlying TNFα-induced endothelial dysfunction

    Article • Atherosclerosis, February 2008, Elsevier

    Jose Martinez Gonzalez, Dr Cristina Rodriguez

  62. Thrombin and protease-activated receptors (PARs) in atherothrombosis

    Article • Thrombosis and Haemostasis, January 2008, Schattauer GmbH

    Professor Lina Badimon, Jose Martinez Gonzalez, Dr Cristina Rodriguez

  63. Lysyl oxidase as a potential therapeutic target

    Article • Drug News & Perspectives, January 2008, Prous Science

    Jose Martinez Gonzalez, Dr Cristina Rodriguez

  64. Metalloproteinases and atherothrombosis: MMP-10 mediates vascular remodeling promoted by inflammatory stimuli

    Article • Frontiers in Bioscience, January 2008, Frontiers in Bioscience

    Jose A. Rodriguez, Jose Martinez Gonzalez, Dr Cristina Rodriguez

  65. C-reactive protein exerts angiogenic effects on vascular endothelial cells and modulates associated signalling pathways and gene expression

    Article • BMC Cell Biology, January 2008, Springer Science + Business Media

    Jose Martinez Gonzalez, Dr Cristina Rodriguez

  66. Lysyl oxidase and endothelial dysfunction: mechanisms of lysyl oxidase down-regulation by pro-inflammatory cytokines

    Article • Frontiers in Bioscience, January 2008, Frontiers in Bioscience

    Jose Martinez Gonzalez, Dr Cristina Rodriguez

  67. Vascular effects of thrombin: Involvement of NOR-1 in thrombin-induced mitogenic stimulus in vascular cells

    Article • Frontiers in Bioscience, January 2008, Frontiers in Bioscience

    Jose Martinez Gonzalez, Dr Cristina Rodriguez

  68. Cell Biology and Lipoproteins in Atherosclerosis

    Article • Current Molecular Medicine, August 2006, Bentham Science Publishers

    Jose Martinez Gonzalez, Dr Cristina Rodriguez

  69. Transcription Factor SOX18 Is Expressed in Human Coronary Atherosclerotic Lesions and Regulates DNA Synthesis and Vascular Cell Growth

    Article • Arteriosclerosis Thrombosis and Vascular Biology, November 2005, Wolters Kluwer Health

    Jose Martinez Gonzalez, Dr Cristina Rodriguez

  70. High levels of homocysteine inhibit lysyl oxidase (LOX) and downregulate LOX expression in vascular endothelial cells

    Article • Atherosclerosis, November 2004, Elsevier

    Professor Lina Badimon, Jose Martinez Gonzalez, Dr Cristina Rodriguez

  71. Modulation of ERG25 expression by LDL in vascular cells

    Article • Cardiovascular Research, April 2003, European Society of Cardiology

    Jose Martinez Gonzalez, Dr Cristina Rodriguez

  72. Fibrate treatment does not modify the expression of acyl coenzyme A oxidase in human liver

    Article • Clinical Pharmacology & Therapeutics, December 2002, Nature

    Dr Cristina Rodriguez

  73. Low-Density Lipoprotein Upregulates Low-Density Lipoprotein Receptor-Related Protein Expression in Vascular Smooth Muscle Cells: Possible Involvement of Sterol Regulatory Element Binding Protein-2-Dependent Mechanism

    Article • Circulation, November 2002, Wolters Kluwer Health

    Dr Cristina Rodriguez

  74. Low Density Lipoproteins Downregulate Lysyl Oxidase in Vascular Endothelial Cells and the Arterial Wall

    Article • Arteriosclerosis Thrombosis and Vascular Biology, August 2002, Wolters Kluwer Health

    Jose Martinez Gonzalez, Dr Cristina Rodriguez

  75. 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibition Prevents Endothelial NO Synthase Downregulation by Atherogenic Levels of Native LDLs : Balance Between Transcriptional and Posttranscriptional Regulation

    Article • Arteriosclerosis Thrombosis and Vascular Biology, May 2001, Wolters Kluwer Health

    Jose Martinez Gonzalez, Dr Cristina Rodriguez

  76. LDL Downregulates CYP51 in Porcine Vascular Endothelial Cells and in the Arterial Wall Through a Sterol Regulatory Element Binding Protein-2-Dependent Mechanism

    Article • Circulation Research, February 2001, Wolters Kluwer Health

    Jose Martinez Gonzalez, Dr Cristina Rodriguez

  77. Differential induction of stearoyl-CoA desaturase and acyl-CoA oxidase genes by fibrates in HepG2 cells

    Article • Biochemical Pharmacology, February 2001, Elsevier

    Dr Cristina Rodriguez

  78. Article • Molecular and Cellular Biochemistry, January 2001, Springer Science + Business Media

    Dr Cristina Rodriguez

  79. Oxidation of low-density lipoproteins in renal transplant recipients

    Article • Transplantation Proceedings, September 1999, Elsevier

    Dr Cristina Rodriguez

  80. Fatty acid composition in low-density lipoproteins from renal transplant recipients

    Article • Transplantation Proceedings, September 1999, Elsevier

    Dr Cristina Rodriguez

  81. Different effects of fibrates on the microsomal fatty acid chain elongation and the acyl composition of phospholipids in guinea-pigs

    Article • British Journal of Pharmacology, December 1995, Wiley

    Dr Cristina Rodriguez