All Stories

  1. Synthesis, Molecular Modeling and Biological Evaluation of Novel Trifluoromethyl Benzamides as Promising CETP Inhibitors

    Article • Current Computer - Aided Drug Design, October 2024, Bentham Science Publishers

    Prof. Reema Abu Khalaf

  2. Trifluoromethylated Aryl Sulfonamides as Novel CETP Inhibitors: Synthesis, Induced Fit Docking, Pharmacophore Mapping and Subsequent In vitro Validation

    Article • Medicinal Chemistry, May 2023, Bentham Science Publishers

    Prof. Reema Abu Khalaf

  3. Synthesis and Molecular Modeling of Novel 3,5-Bis(trifluoromethyl) benzylamino Benzamides as Potential CETP Inhibitors

    Article • Medicinal Chemistry, May 2022, Bentham Science Publishers

    Prof. Reema Abu Khalaf, MSc Mohammad Awad

  4. Synthesis, Biological Evaluation, and QPLD Studies of Piperazine Derivatives as Potential DPP-IV Inhibitors

    Article • Medicinal Chemistry, November 2021, Bentham Science Publishers

    Prof. Reema Abu Khalaf

  5. Piperazine sulfonamides as DPP-IV inhibitors: Synthesis, induced-fit docking and in vitro biological evaluation

    Article • Acta Pharmaceutica, April 2021, De Gruyter

    Prof. Reema Abu Khalaf

  6. DPP-IV Inhibitory Phenanthridines: Ligand, Structure-Based Design and Synthesis

    Article • Current Computer - Aided Drug Design, June 2020, Bentham Science Publishers

    Prof. Reema Abu Khalaf

  7. Ligand-Based Drug Design: Synthesis and Biological Evaluation of Substituted Benzoin Derivatives as Potential Antitumor Agents

    Article • Medicinal Chemistry, September 2018, Bentham Science Publishers

    Prof. Reema Abu Khalaf, Prof. Dima A. Sabbah, Wamidh Talib, sanaa bardaweel, Ghassan Abu Sheikha, Mohammad S. Mubarak

  8. Synthesis, Structural Characterization and Docking Studies of Sulfamoyl- Phenyl Acid Esters as Dipeptidyl Peptidase-IV Inhibitors

    Article • Current Computer - Aided Drug Design, May 2018, Bentham Science Publishers

    Prof. Reema Abu Khalaf

  9. Structure-Based Design: Synthesis, X-ray Crystallography, and Biological Evaluation of N-Substituted-4-Hydroxy-2-Quinolone-3-Carboxamides as Potential Cytotoxic Agents

    Article • Anti-Cancer Agents in Medicinal Chemistry, April 2018, Bentham Science Publishers

    Prof. Dima A. Sabbah, kamal sweidan, Prof. Reema Abu Khalaf, Mohammad S. Mubarak, Ghassan Abu Sheikha, sanaa bardaweel

  10. Benzoin Schiff Bases: Design, Synthesis, and Biological Evaluation as Potential Antitumor Agents

    Article • Medicinal Chemistry, April 2018, Bentham Science Publishers

    Prof. Dima A. Sabbah, Ghassan Abu Sheikha, Prof. Reema Abu Khalaf, Mohammad S. Mubarak, sanaa bardaweel

  11. Synthesis of Novel Benzimidazole-2-carboxamide Derivatives and in Vivo Antihyperlipidemic Activity Evaluation

    Article • Chemical and Pharmaceutical Bulletin, January 2018, Pharmaceutical Society of Japan

    Prof. Reema Abu Khalaf

  12. Benzamides as CETP Inhibitors

    Article • Archiv der Pharmazie, November 2017, Wiley

    Prof. Reema Abu Khalaf, Ghassan Abu Sheikha

  13. CETP Inhibitory Activity of Chlorobenzyl Benzamides: QPLD Docking, Pharmacophore Mapping and Synthesis

    Article • Letters in Drug Design & Discovery, October 2017, Bentham Science Publishers

    Prof. Dima A. Sabbah, Prof. Reema Abu Khalaf, HAMADA ABDELAZIZ, Ghassan Abu Sheikha

  14. Molecular Docking and Pharmacophore Modeling Studies of Fluorinated Benzamides as Potential CETP Inhibitors

    Article • Medicinal Chemistry, April 2017, Bentham Science Publishers

    Prof. Reema Abu Khalaf

  15. Synthesis and in vivo anti-hyperlipidemic activity of novel n-benzoylphenyl-2-furamide derivatives in Wistar rats

    Article • Tropical Journal of Pharmaceutical Research, February 2017, African Journals Online (AJOL)

    Prof. Reema Abu Khalaf

  16. Exploring Natural Products as a Source for Antidiabetic Lead Compounds and Possible Lead Optimization

    Article • Current Topics in Medicinal Chemistry, July 2016, Bentham Science Publishers

    Prof. Reema Abu Khalaf

  17. Molecular modeling based approach, synthesis, and cytotoxic activity of novel benzoin derivatives targeting phosphoinostide 3-kinase (PI3Kα)

    Article • Bioorganic & Medicinal Chemistry Letters, August 2015, Elsevier

    Prof. Reema Abu Khalaf

  18. Pharmacophore modeling and molecular docking studies of acridines as potential DPP-IV inhibitors

    Article • Canadian Journal of Chemistry, July 2015, Canadian Science Publishing

    Prof. Reema Abu Khalaf

  19. Tryptophan and thiosemicarbazide derivatives: design, synthesis, and biological evaluation as potential β-d-galactosidase and β-d-glucosidase inhibitors

    Article • Medicinal Chemistry Research, December 2014, Springer Science + Business Media

    Prof. Reema Abu Khalaf, prof mutasem taha

  20. Design, Synthesis and Biological Evaluation of N4-Sulfonamido- Succinamic, Phthalamic, Acrylic and Benzoyl Acetic Acid Derivatives as Potential DPP IV Inhibitors

    Article • The Open Medicinal Chemistry Journal, November 2013, Bentham Science Publishers

    Prof. Reema Abu Khalaf, Associate Professor Mahmoud A Al-Sha'er, prof mutasem taha

  21. In Vivo Antihyperlipidemic Activity of a New Series of N-(Benzoylphenyl) and N-(Acetylphenyl)-1-benzofuran-2-carboxamides in Rats

    Article • Archiv der Pharmazie, January 2012, Wiley

    Dr Waseem El-huneidi, Prof. Reema Abu Khalaf

  22. Design, synthesis, and biological evaluation of sulfonic acid ester and benzenesulfonamide derivatives as potential CETP inhibitors

    Article • Medicinal Chemistry Research, November 2011, Springer Science + Business Media

    Prof. Reema Abu Khalaf, Associate Professor Mahmoud A Al-Sha'er, prof mutasem taha

  23. Discovery of New Antifungal Leads via Pharmacophore Modeling and QSAR Analysis of Fungal N‐Myristoyl Transferase Inhibitors Followed by In Silico Screening

    Article • Chemical Biology & Drug Design, July 2011, Wiley

    Professor Amjad M. Qandil, Prof. Reema Abu Khalaf, prof mutasem taha

  24. Discovery of new β-D-galactosidase inhibitors via pharmacophore modeling and QSAR analysis followed by in silico screening

    Article • Journal of Computational Chemistry, August 2010, Wiley

    Prof. Reema Abu Khalaf, prof mutasem taha

  25. Design, Synthesis, and Biological Evaluation of Benzylamino-Methanone Based Cholesteryl Ester Transfer Protein Inhibitors

    Article • Molecules, August 2010, MDPI AG

    Prof. Reema Abu Khalaf

  26. Discovery of new β-d-glucosidase inhibitors via pharmacophore modeling and QSAR analysis followed by in silico screening

    Article • Journal of Molecular Modeling, May 2010, Springer Science + Business Media

    Prof. Reema Abu Khalaf, prof mutasem taha

  27. Discovery of new cholesteryl ester transfer protein inhibitors via ligand-based pharmacophore modeling and QSAR analysis followed by synthetic exploration

    Article • European Journal of Medicinal Chemistry, April 2010, Elsevier

    Prof. Reema Abu Khalaf, prof mutasem taha