All Stories

  1. Human FcRn expression and Type I Interferon signaling control Echovirus 11 pathogenesis in mice

    Article • PLoS Pathogens, January 2021, PLOS

    Dr Carolyn Coyne

  2. Recommendations for future university pandemic responses: What the first COVID-19 shutdown taught us

    Article • PLoS Biology, August 2020, PLOS

    Dr Carolyn Coyne, Dr Ira J Blader

  3. The exoribonuclease Xrn1 is a post-transcriptional negative regulator of autophagy

    Article • Autophagy, March 2018, Taylor & Francis

    Dr Carolyn Coyne, Daniel Klionsky

  4. Human Placental Syncytiotrophoblasts Restrict Toxoplasma gondii Attachment and Replication and Respond to Infection by Producing Immunomodulatory Chemokines

    Article • mBio, January 2018, ASM Journals

    Dr Carolyn Coyne

  5. Human placental syncytiotrophoblasts restrict Toxoplasma gondii vertical transmission at two distinct stages and induce CCL22 in response to infection

    Article • August 2017, Cold Spring Harbor Laboratory Press

    Dr Carolyn Coyne

  6. Expression and trafficking of placental microRNAs at the feto-maternal interface

    Article • The FASEB Journal, July 2017, Federation of American Societies For Experimental Biology (FASEB)

    Dr Carolyn Coyne

  7. A Three-Dimensional Cell Culture System To Model RNA Virus Infections at the Blood-Brain Barrier

    Article • mSphere, June 2017, ASM Journals

    Dr Carolyn Coyne

  8. Enteroviruses infect human enteroids and induce antiviral signaling in a cell lineage-specific manner

    Article • Proceedings of the National Academy of Sciences, January 2017, Proceedings of the National Academy of Sciences

    Dr Carolyn Coyne

  9. Dengue and Zika viruses subvert reticulophagy by NS2B3-mediated cleavage of FAM134B

    Article • Autophagy, January 2017, Taylor & Francis

    Dr Carolyn Coyne

  10. Screening Bioactives Reveals Nanchangmycin as a Broad Spectrum Antiviral Active against Zika Virus

    Article • Cell Reports, January 2017, Elsevier

    Dr Carolyn Coyne

  11. Zika virus — reigniting the TORCH

    Article • Nature Reviews Microbiology, August 2016, Nature

    Dr Carolyn Coyne

  12. Mechanisms of Zika Virus Infection and Neuropathogenesis

    Article • DNA and Cell Biology, August 2016, Mary Ann Liebert Inc

    Dr Carolyn Coyne

  13. Type III Interferons Produced by Human Placental Trophoblasts Confer Protection against Zika Virus Infection

    Article • Cell Host & Microbe, May 2016, Elsevier

    Dr Carolyn Coyne

  14. The Tree(s) of Life: The Human Placenta and My Journey to Learn More about It

    Article • PLoS Pathogens, April 2016, PLOS

    Dr Carolyn Coyne

  15. BPIFB6 Regulates Secretory Pathway Trafficking and Enterovirus Replication

    Article • Journal of Virology, March 2016, ASM Journals

    Dr Carolyn Coyne

  16. A three-dimensional culture system recapitulates placental syncytiotrophoblast development and microbial resistance

    Article • Science Advances, March 2016, American Association for the Advancement of Science

    Dr Carolyn Coyne

  17. A Three-Dimensional Cell Culture Model To Study Enterovirus Infection of Polarized Intestinal Epithelial Cells

    Article • mSphere, November 2015, ASM Journals

    Dr Carolyn Coyne

  18. Unc93b Induces Apoptotic Cell Death and Is Cleaved by Host and Enteroviral Proteases

    Article • PLoS ONE, October 2015, PLOS

    Dr Carolyn Coyne

  19. MicroRNAs in placental health and disease

    Article • American Journal of Obstetrics and Gynecology, October 2015, Elsevier

    Dr Carolyn Coyne

  20. ADAP2 Is an Interferon Stimulated Gene That Restricts RNA Virus Entry

    Article • PLoS Pathogens, September 2015, PLOS

    Dr Carolyn Coyne

  21. RIP3 Regulates Autophagy and Promotes Coxsackievirus B3 Infection of Intestinal Epithelial Cells

    Article • Cell Host & Microbe, August 2015, Elsevier

    Dr Carolyn Coyne

  22. MiRNA trafficking across the maternal-placental-fetal compartments

    Article • Placenta, April 2015, Elsevier

    Dr Carolyn Coyne

  23. Catch Me If You Can: The Link between Autophagy and Viruses

    Article • PLoS Pathogens, March 2015, PLOS

    Dr Carolyn Coyne

  24. BPIFB3 Regulates Autophagy and Coxsackievirus B Replication through a Noncanonical Pathway Independent of the Core Initiation Machinery

    Article • mBio, December 2014, ASM Journals

    Dr Carolyn Coyne

  25. The Placenta as a Barrier to Viral Infections

    Article • Annual Review of Virology, November 2014, Annual Reviews

    Dr Carolyn Coyne

  26. MiRNA nano-packages for maternal-placental-fetal communication

    Article • Placenta, September 2014, Elsevier

    Dr Carolyn Coyne

  27. Autophagy as a mechanism of antiviral defense at the maternal–fetal interface

    Article • Autophagy, December 2013, Taylor & Francis

    Dr Carolyn Coyne

  28. Mechanisms of MAVS Regulation at the Mitochondrial Membrane

    Article • Journal of Molecular Biology, December 2013, Elsevier

    Dr Carolyn Coyne

  29. Enter at your own risk: How enteroviruses navigate the dangerous world of pattern recognition receptor signaling

    Article • Cytokine, September 2013, Elsevier

    Dr Carolyn Coyne

  30. Lipid Raft- and Src Family Kinase-Dependent Entry of Coxsackievirus B into Human Placental Trophoblasts

    Article • Journal of Virology, May 2013, ASM Journals

    Dr Carolyn Coyne

  31. Picornavirus Entry

    Article • January 2013, Springer Science + Business Media

    Dr Carolyn Coyne

  32. PAMPs and DAMPs: signal 0s that spur autophagy and immunity

    Article • Immunological Reviews, August 2012, Wiley

    Dr Carolyn Coyne

  33. The Actin Cytoskeleton as a Barrier to Virus Infection of Polarized Epithelial Cells

    Article • Viruses, December 2011, MDPI AG

    Dr Carolyn Coyne

  34. Release of Intracellular Calcium Stores Facilitates Coxsackievirus Entry into Polarized Endothelial Cells

    Article • PLoS Pathogens, October 2010, PLOS

    Dr Carolyn Coyne