All Stories

  1. Decorin suppresses tumor lymphangiogenesis: A mechanism to curtail cancer progression
  2. Key roles for the small leucine-rich proteoglycans in renal and pulmonary pathophysiology
  3. Decorin deficiency promotes hepatic carcinogenesis
  4. De novo expression of circulating biglycan evokes an innate inflammatory tissue response via MyD88/TRIF pathways
  5. Biglycan and decorin differentially regulate signaling in the fetal membranes
  6. Decorin differentially modulates the activity of insulin receptor isoform A ligands
  7. A decorin-deficient matrix affects skin chondroitin/dermatan sulfate levels and keratinocyte function
  8. Reprint of: Decorin activates AMPK, an energy sensor kinase, to induce autophagy in endothelial cells
  9. The injury response of aged tendons in the absence of biglycan and decorin
  10. The role of vascular-derived perlecan in modulating cell adhesion, proliferation and growth factor signaling
  11. Biglycan-triggered TLR-2- and TLR-4-signaling exacerbates the pathophysiology of ischemic acute kidney injury
  12. Decorin activates AMPK, an energy sensor kinase, to induce autophagy in endothelial cells
  13. Matrix Biologists in Action
  14. Announcement – MBE Meeting
  15. Osteoblastic cell secretome: A novel role for progranulin during risedronate treatment
  16. ELAF posters
  17. Decorin has an appetite for endothelial cell autophagy
  18. The location-specific role of proteoglycans in the flexor carpi ulnaris tendon
  19. The Tendon Injury Response is Influenced by Decorin and Biglycan
  20. 11C-meta-hydroxyephedrine PET/CT imaging allows in vivo study of adaptive thermogenesis and white-to-brown fat conversion
  21. Intracellularly-Retained Decorin Lacking the C-Terminal Ear Repeat Causes ER Stress
  22. Heparanase: Multiple functions in inflammation, diabetes and atherosclerosis
  23. Decorin interferes with platelet‐derived growth factor receptor signaling in experimental hepatocarcinogenesis
  24. Endorepellin laminin‐like globular 1/2 domains bind Ig3–5 of vascular endothelial growth factor (VEGF) receptor 2 and block pro‐angiogenic signaling by VEGFA in endothelial cells
  25. Biological interplay between proteoglycans and their innate immune receptors in inflammation
  26. Dichotomy of decorin activity on the insulin‐like growth factor‐I system
  27. Decorin induces rapid secretion of thrombospondin‐1 in basal breast carcinoma cells via inhibition of Ras homolog gene family, member A/Rho‐associated coiled‐coil containing protein kinase 1
  28. Effect of Age and Proteoglycan Deficiency on Collagen Fiber Re-Alignment and Mechanical Properties in Mouse Supraspinatus Tendon
  29. Decorin expression is important for age-related changes in tendon structure and mechanical properties
  30. Obesity and Diabetes
  31. The Dermatan Sulfate Proteoglycan Decorin Modulates α2β1 Integrin and the Vimentin Intermediate Filament System during Collagen Synthesis
  32. Decorin Protein Core Affects the Global Gene Expression Profile of the Tumor Microenvironment in a Triple-Negative Orthotopic Breast Carcinoma Xenograft Model
  33. 3.5 Small leucine-rich proteoglycans: multifunctional signaling effectors
  34. 3.4 The biology of perlecan and its bioactive modules
  35. Decorin
  36. Proline-Rich Tyrosine Kinase 2 (Pyk2) Regulates IGF-I-Induced Cell Motility and Invasion of Urothelial Carcinoma Cells
  37. Small leucine-rich proteoglycans orchestrate receptor crosstalk during inflammation
  38. Targeting heparanase for cancer therapy at the tumor–matrix interface
  39. Thrombospondins in physiology and disease: New tricks for old dogs
  40. Small leucine-rich proteoglycans, at the crossroad of cancer growth and inflammation
  41. Decorin–TGFβ Axis in Hepatic Fibrosis and Cirrhosis
  42. Uterine Dysfunction in Biglycan and Decorin Deficient Mice Leads to Dystocia during Parturition
  43. Influence of Decorin on the Mechanical, Compositional, and Structural Properties of the Mouse Patellar Tendon
  44. Pathophysiological Mechanisms of Autosomal Dominant Congenital Stromal Corneal Dystrophy
  45. Autophagic tumor stroma: A biofuel for cancer growth
  46. Scleroderma-like properties of skin from caveolin-1-deficient mice
  47. Influence of Decorin and Biglycan on Tensile Viscoelastic Properties in Knockout Mice
  48. Mitostatin Is Down-Regulated in Human Prostate Cancer and Suppresses the Invasive Phenotype of Prostate Cancer Cells
  49. Proteoglycans in cancer biology, tumour microenvironment and angiogenesis
  50. Myocardial, Perivascular, and Epicardial Fat
  51. Ablation of the decorin gene enhances experimental hepatic fibrosis and impairs hepatic healing in mice
  52. Caveolin-1 and mitochondrial SOD2 (MnSOD) function as tumor suppressors in the stromal microenvironment
  53. Small Leucine-Rich Proteoglycans
  54. Proteoglycans in health and disease: emerging concepts and future directions
  55. Proteoglycans in health and disease: novel regulatory signaling mechanisms evoked by the small leucine‐rich proteoglycans
  56. Letter from Renato V. Iozzo
  57. Heparan Sulfate-Dependent Signaling of Fibroblast Growth Factor 18 by Chondrocyte-Derived Perlecan
  58. The Insulin-Like Growth Factor Receptor I Promotes Motility and Invasion of Bladder Cancer Cells through Akt- and Mitogen-Activated Protein Kinase-Dependent Activation of Paxillin
  59. Metabolic toxicity of the heart: Insights from molecular imaging
  60. Necrotizing vasculitis in a patient affected by autoimmune hyperthyroidism treated with propylthiouracil
  61. Myeloperoxidase-derived oxidants selectively disrupt the protein core of the heparan sulfate proteoglycan perlecan
  62. Collagen fibril organization in the pregnant endometrium of decorin‐deficient mice
  63. Viewpoints on the Way to the Consensus Session
  64. A Key Role for the Integrin α2β1 in Experimental and Developmental Angiogenesis
  65. Topographical variation in the distributions of versican, aggrecan and perlecan in the foetal human spine reflects their diverse functional roles in spinal development
  66. Perlecan regulates developmental angiogenesis by modulating the VEGF-VEGFR2 axis
  67. Basement Membrane Proteoglycans: Modulators Par Excellence of Cancer Growth and Angiogenesis
  68. PROEPITHELIN IS A NOVEL BIOMARKER FOR PROSTATE CANCER AND REGULATES CELL GROWTH, MIGRATION AND ANCHORAGE-INDEPENDENT GROWTH OF PROSTATE CANCER CELLS
  69. Genetic evidence for key roles of decorin and biglycan in dentin mineralization
  70. Proepithelin Regulates Prostate Cancer Cell Biology by Promoting Cell Growth, Migration, and Anchorage-Independent Growth
  71. A central role for decorin during vertebrate convergent extension
  72. Endorepellin evokes SHP1 activity in endothelial cells
  73. Decorin binds to and downregulates the MET receptor
  74. Small molecule inhibitors of collagen-induced angiogenesis
  75. Diverse Cell Signaling Events Modulated by Perlecan
  76. Tumor microenvironment: Modulation by decorin and related molecules harboring leucine‐rich tandem motifs
  77. An Antimetastatic Role for Decorin in Breast Cancer
  78. Urinary proteomic analysis of chronic allograft nephropathy
  79. Influence of cyclic strain and decorin deficiency on 3D cellularized collagen matrices
  80. MITOSTATIN, A NOVEL MITOCHONDRIAL PROTEIN, THAT ACTS AS A TUMOR SUPPRESSOR IN PROSTATE CANCER CELLS
  81. Novel interactions of perlecan: Unraveling perlecan's role in angiogenesis
  82. Recombinant heparan sulfate for use in tissue engineering applications
  83. Proteomic profiling of endorepellin angiostatic activity on human endothelial cells
  84. Decorin Deficiency Enhances Progressive Nephropathy in Diabetic Mice
  85. The glycosaminoglycan chain of decorin plays an important role in collagen fibril formation at the early stages of fibrillogenesis
  86. Positron Emission Tomography in Metabolic Research
  87. Impaired posterior frontal sutural fusion in the biglycan/decorin double deficient mice
  88. Decorin-Mediated Regulation of Fibrillin-1 in the Kidney Involves the Insulin-Like Growth Factor-I Receptor and Mammalian Target of Rapamycin
  89. Soluble LRIG1 inhibits cancer cell growth
  90. Actin' Up: Endorepellin and endothelial morphogenesis
  91. Endothelial cell_collagen interactions in angiogenesis
  92. A role for decorin in cutaneous wound healing and angiogenesis
  93. Decorin regulates assembly of collagen fibrils and acquisition of biomechanical properties during tendon development
  94. The role of proteomics in the assessment of premature rupture of fetal membranes
  95. Heparan Sulfate: A Complex Polymer Charged with Biological Activity
  96. Basement membrane proteoglycans: from cellar to ceiling
  97. A physiologic three-dimensional cell culture system to investigate the role of decorin in matrix organisation and cell survival
  98. Heparan Sulfate:  A Complex Polymer Charged with Biological Activity
  99. Matrix revolutions: ‘tails’ of basement-membrane components with angiostatic functions
  100. Influence of Decorin and Biglycan on Mechanical Properties of Multiple Tendons in Knockout Mice
  101. Decorin prevents metastatic spreading of breast cancer
  102. Protective Niche for Borrelia burgdorferi to Evade Humoral Immunity
  103. Regulation of Fibrillin-1 by Biglycan and Decorin Is Important for Tissue Preservation in the Kidney During Pressure-Induced Injury
  104. Investigating Tendon Fascicle Structure–Function Relationships in a Transgenic-Age Mouse Model Using Multiple Regression Models
  105. Strain-Rate Sensitive Mechanical Properties of Tendon Fascicles From Mice With Genetically Engineered Alterations in Collagen and Decorin
  106. Decorin Deficiency Leads to Impaired Angiogenesis in Injured Mouse Cornea
  107. Effect of Altered Matrix Proteins on Quasilinear Viscoelastic Properties in Transgenic Mouse Tail Tendons
  108. Androgen receptor expression induces FGF2, FGF‐binding protein production, and FGF2 release in prostate carcinoma cells: Role of FGF2 in growth, survival, and androgen receptor down‐modulation
  109. Decorin suppresses tumor cell-mediated angiogenesis
  110. Renato V. Iozzo (ed): Proteoglycan protocols
  111. Suppression of tumorigenicity by adenovirus-mediated gene transfer of decorin
  112. The role of decorin in collagen fibrillogenesis and skin homeostasis
  113. Absence of Decorin Adversely Influences Tubulointerstitial Fibrosis of the Obstructed Kidney by Enhanced Apoptosis and Increased Inflammatory Reaction
  114. Isolation and purification of proteoglycans
  115. A role for the perlecan protein core in the activation of the keratinocyte growth factor receptor
  116. Heparan sulfate proteoglycans: heavy hitters in the angiogenesis arena
  117. Heparan sulfate proteoglycans: heavy hitters in the angiogenesis arena
  118. Series Introduction: Heparan sulfate proteoglycans: intricate molecules with intriguing functions
  119. Series Introduction: Heparan sulfate proteoglycans: intricate molecules with intriguing functions
  120. Proteoglycan Protocols
  121. Proteoglycans: Structure, Biology, and Molecular Interactions Renato V. Iozzo
  122. Glycosaminoglycans: Structure and Biological Functions
  123. Resistance to Lyme disease in decorin-deficient mice
  124. A Role for Decorin in the Structural Organization of Periodontal Ligament
  125. Activation of extracellular signal-regulated protein kinase1,2 results in down-regulation of decorin expression in fibroblasts
  126. Proteoglycans
  127. Introductory Remarks and Overview
  128. Fibroblast growth factor-2
  129. Human perlecan immunopurified from different endothelial cell sources has different adhesive properties for vascular cells
  130. Decorin Is a Biological Ligand for the Epidermal Growth Factor Receptor
  131. Decorin, epiphycan, and lumican genes are closely linked on murine Chromosome 10 and are deleted in lethal steel mutants
  132. There Is Binding of Collagen IV to β1 Integrin during Early Skin Basement Membrane Assembly
  133. MATRIX PROTEOGLYCANS: From Molecular Design to Cellular Function
  134. Transcriptional and Posttranscriptional Regulation of Proteoglycan Gene Expression
  135. Ectopic expression of decorin protein core causes generalized growth suppression in neoplastic cells of various histogenetic origin and requires endogenous p21, an inhibitor of cyclin-dependent kinases
  136. Altered Proteoglycan Gene Expression in Human Biliary Cirrhosis
  137. The Family of the Small Leucine-Rich Proteoglycans: Key Regulators of Matrix Assembly and Cellular Growth
  138. The Murine Biglycan: Complete cDNA Cloning, Genomic Organization, Promoter Function, and Expression
  139. Expression Pattern and Mapping of the Murine Versican Gene (Cspg2) to Chromosome 13
  140. The proteoglycan perlecan is expressed in the erythroleukemia cell line K562 and is upregulated by sodium butyrate and phorbol ester
  141. Decorin gene transcription: Up-regulation upon cellular quiescence and down-regulation by tumor necrosis factor-α
  142. Formation of nodular structures resembling mature articular cartilage in long–term primary cultures of human fetal epiphyseal chondrocytes on a hydrogel substrate
  143. Perlecan: A gem of a proteoglycan
  144. ChemInform Abstract: Altered Proteoglycan Gene Expression and the Tumor Stroma
  145. Altered proteoglycan gene expression and the tumor stroma
  146. Molecular Cloning of the Human Proto-oncogene Wnt-5A and Mapping of the Gene (WNT5A) to Chromosome 3p14-p21
  147. Stimulation of protein synthesis in isolated pancreatic acini from chronically ethanol-fed rats is due to alterations in post-transcriptional regulation
  148. Perlecan: The multidomain heparan sulphate proteoglycan of basement membrane and extracellular matrix
  149. Altered proteoglycan gene expression and the tumor stroma
  150. The Human Decorin Gene: Intron-Exon Organization, Discovery of Two Alternatively Spliced Exons in the 5′ Untranslated Region, and Mapping of the Gene to Chromosome 12q23
  151. Mapping of the versican proteoglycan gene (CSPG2) to the long arm of human chromosome 5 (5q12–5q14)
  152. Establishment of a Cell Line from the EHS Tumor: Biosynthesis of Basement Membrane Constituents and Characterization of a Hybrid Proteoglycan Containing Heparan and Chondroitin Sulfate Chains
  153. Biosynthetic and proliferative characteristics of tubulointerstitial fibroblasts probed with paracrine cytokines
  154. Larsen's syndrome with novel congenital anomalies
  155. Human clathrin heavy chain (CLTC): Partial molecular cloning, expression, and mapping of the gene to human chromosome 17q11-qter
  156. Heparan sulfate proteoglycan of human colon: Partial molecular cloning, cellular expression, and mapping of the gene (HSPG2) to the short arm of human chromosome 1
  157. Lipid-Linked Heparan Sulfate Proteoglycan.
  158. Myristoylation of heparan sulfate proteoglycan and proteins occurs post-translationally in human colon carcinoma cells
  159. Altered methylation of versican proteoglycan gene in human colon carcinoma
  160. Inhibition of Proteoglycan Synthesis in Human Endothelial Cells after Infection with Herpes Simplex Virus Type 1In Vitro
  161. Altered glycosaminoglycan composition in reactive and neoplastic human liver
  162. Sequences
  163. Large animal model of left ventricular aneurysm
  164. Receptors for and bioresponses to 1,25-dihydroxyvitamin D in a human colon carcinoma cell line (HT-29)
  165. Bovine Pericardial Proteoglycan: Biochemical, Immunochemical and Ultrastructural Studies
  166. Heparin and endothelial cell growth factor modulate collagen and proteoglycan production in human smooth muscle cells
  167. Neoplastic modulation of extracellular matrix: Stimulation of chondroitin sulfate proteoglycan and hyaluronic acid synthesis in co‐cultures of human colon carcinoma and smooth muscle cells
  168. Identification of the precursor protein for the heparan sulfate proteoglycan of human colon carcinoma cells and its post-translational modifications
  169. Collagen matrix influences the morphologic features and steroid secretion of human granulosa cells
  170. Cell surface heparan sulfate proteoglycan and the neoplastic phenotype
  171. Proteoglycans and neoplasia
  172. Corinthian Basins on High Stands
  173. Experimental Myocardial Cryoinjury: Local Electromechanical Changes, Arrhythmogenicity, and Methods for Determining Depth of Injury
  174. Proteoglycans and the Intercellular Tumor Matrix
  175. Evidence of a small hydrophobic domain in the core protein of the heparan sulfate proteoglycan from human colon carcinoma cells
  176. MURCS association with additional congenital anomalies
  177. Early diagnosis of experimental necrotizing enterocolitis using proton nuclear magnetic resonance
  178. Anatomic and hemodynamic effects of catheter-delivered ablation energies in the ventricle
  179. Proteoglycans and neoplastic—mesenchymal cell interactions
  180. Analysis of proteoglycans by high-performance liquid chromatography: A rapid micromethod for the separation of proteoglycans from tissue and cell culture
  181. Cerebral infarction complicating umbilical vein catheterization
  182. Prokaryotic Expression of Proteoglycans
  183. Proteoglycan Gene Targeting in Somatic Cells
  184. Constitutive and Inducible Antisense Expression
  185. Interaction of Proteoglycans with Receptor Tyrosine Kinases
  186. Measuring Single-Cell Cytosolic Ca<sup>2+</sup> Concentration in Response to Proteoglycans