All Stories

  1. Genetic characterization and pathogenic potential of H10 avian influenza viruses isolated from live poultry markets in Bangladesh
  2. mTOR coordinates transcriptional programs and mitochondrial metabolism of activated Treg subsets to protect tissue homeostasis
  3. GSDMD is critical for autoinflammatory pathology in a mouse model of Familial Mediterranean Fever
  4. Virulent PB1-F2 residues: effects on fitness of H1N1 influenza A virus in mice and changes during evolution of human influenza A viruses
  5. Critical roles of mTORC1 signaling and metabolic reprogramming for M-CSF–mediated myelopoiesis
  6. Globule Leukocytes and Other Mast Cells in the Mouse Intestine
  7. H1N1 influenza viruses varying widely in hemagglutinin stability transmit efficiently from swine to swine and to ferrets
  8. Exogenous remodeling of lung resident macrophages protects against infectious consequences of bone marrow-suppressive chemotherapy
  9. Keratinocytes contribute intrinsically to psoriasis upon loss of Tnip1 function
  10. ZBP1/DAI is an innate sensor of influenza virus triggering the NLRP3 inflammasome and programmed cell death pathways
  11. Antibody-secreting cells in respiratory tract tissues in the absence of eosinophils as supportive partners
  12. Dentin Dysplasia in Notum Knockout Mice
  13. GREMLIN 2 Mutations and Dental Anomalies
  14. Relationships among Dissemination of Primary Parainfluenza Virus Infection in the Respiratory Tract, Mucosal and Peripheral Immune Responses, and Protection from Reinfection: a Noninvasive Bioluminescence-Imaging Study
  15. Drak2 is not required for tumor surveillance and suppression
  16. Malformation of Incisor Teeth in Grem2-/- Mice
  17. Cutting Edge: STING Mediates Protection against Colorectal Tumorigenesis by Governing the Magnitude of Intestinal Inflammation
  18. Neurologic Abnormalities in Mouse Models of the Lysosomal Storage Disorders Mucolipidosis II and Mucolipidosis III γ
  19. Human H7N9 and H5N1 Influenza Viruses Differ in Induction of Cytokines and Tissue Tropism
  20. Nephronophthisis and Retinal Degeneration in Tmem218–/– Mice
  21. The Weaned Pig as a Model for Doxorubicin-Induced Mucositis
  22. Recipient Myeloid-Derived Immunomodulatory Cells Induce PD-1 Ligand-Dependent Donor CD4+Foxp3+ Regulatory T Cell Proliferation and Donor-Recipient Immune Tolerance after Murine Nonmyeloablative Bone Marrow Transplantation
  23. Targeted disruption of leucine-rich repeat kinase 1 but not leucine-rich repeat kinase 2 in mice causes severe osteopetrosis
  24. Stability and function of regulatory T cells is maintained by a neuropilin-1–semaphorin-4a axis
  25. mTORC1 couples immune signals and metabolic programming to establish Treg-cell function
  26. RIP1-driven autoinflammation targets IL-1α independently of inflammasomes and RIP3
  27. Compromised respiratory function in lethal influenza infection is characterized by the depletion of type I alveolar epithelial cells beyond threshold levels
  28. Receptor interacting protein kinase 2–mediated mitophagy regulates inflammasome activation during virus infection
  29. Improved glycemic control in mice lacking Sglt1 and Sglt2
  30. Transporters on Arachnoid barrier cells
  31. Cryptogenic Organizing Pneumonia in Tomm5–/– Mice
  32. Response to Guest Editorial (“Veterinary Pathology Under the Microscope: Planning for the Future”)
  33. Toll or Interleukin-1 Receptor (TIR) Domain-containing Adaptor Inducing Interferon-β (TRIF)-mediated Caspase-11 Protease Production Integrates Toll-like Receptor 4 (TLR4) Protein- and Nlrp3 Inflammasome-mediated Host Defense against Enteropathogens
  34. NLRP6 negatively regulates innate immunity and host defence against bacterial pathogens
  35. Amelogenesis Imperfecta and Other Biomineralization Defects in Fam20a and Fam20c Null Mice
  36. A Single Point Mutation (Y89F) within the Non-Structural Protein 1 of Influenza A Viruses Limits Epithelial Cell Tropism and Virulence in Mice
  37. Abcb11 Deficiency Induces Cholestasis Coupled to Impaired  -Fatty Acid Oxidation in Mice
  38. Role of Inflammasomes in Host Defense againstCitrobacter rodentiumInfection
  39. Enhanced Susceptibility of Ago1/3 Double-Null Mice to Influenza A Virus Infection
  40. Transforming growth factor beta-activated kinase 1 (TAK1)-dependent checkpoint in the survival of dendritic cells promotes immune homeostasis and function
  41. Signaling via the kinase p38α programs dendritic cells to drive TH17 differentiation and autoimmune inflammation
  42. Congenital Hydrocephalus in Genetically Engineered Mice
  43. Immune Inhibitory Molecules LAG-3 and PD-1 Synergistically Regulate T-cell Function to Promote Tumoral Immune Escape
  44. The NOD-Like Receptor NLRP12 Attenuates Colon Inflammation and Tumorigenesis
  45. Exploring the elephant: histopathology in high-throughput phenotyping of mutant mice
  46. Cardiomyopathy in α-Kinase 3 (ALPK3)–Deficient Mice
  47. A mouse model of hereditary folate malabsorption: deletion of the PCFT gene leads to systemic folate deficiency
  48. Host Myeloid-Derived Suppressor Cells Induce Donor Treg Proliferation and Transplantation Tolerance Via IL-4Rα/STAT6 After TLI/ATS Non-Myeloablative BMT
  49. Profound Obesity Secondary to Hyperphagia in Mice Lacking Kinase Suppressor of Ras 2
  50. Pathology of Congenital Generalized Lipodystrophy in Agpat2–/– Mice
  51. Regulators of the Proteasome Pathway, Uch37 and Rpn13, Play Distinct Roles in Mouse Development
  52. IL-18 Production Downstream of the Nlrp3 Inflammasome Confers Protection against Colorectal Tumor Formation
  53. Tubulin Tyrosine Ligase–Like 1 Deficiency Results in Chronic Rhinosinusitis and Abnormal Development of Spermatid Flagella in Mice
  54. Spontaneous Acute Tumor Lysis Syndrome as a Cause of Early Deaths in Short-Term Carcinogenicity Studies Using p53+/– Mice
  55. Early Toxicology Signal Generation in the Mouse
  56. The NLRP3 Inflammasome Protects against Loss of Epithelial Integrity and Mortality during Experimental Colitis
  57. Situs Inversus in Dpcd/Poll–/–, Nme7–/–, and Pkd1l1–/– Mice
  58. Comparative Pathology of Murine Mucolipidosis Types II and IIIC
  59. Incomplete Inhibition of Sphingosine 1-Phosphate Lyase Modulates Immune System Function yet Prevents Early Lethality and Non-Lymphoid Lesions
  60. Learning and memory impairment in Eph receptor A6 knockout mice
  61. Ocular Albinism and Hypopigmentation Defects in Slc24a5—I— Mice
  62. Discovery and Characterization of Novel Tryptophan Hydroxylase Inhibitors That Selectively Inhibit Serotonin Synthesis in the Gastrointestinal Tract
  63. Mice Lacking α/β Subunits of GlcNAc-1-Phosphotransferase Exhibit Growth Retardation, Retinal Degeneration, and Secretory Cell Lesions
  64. Lipid-lowering effects of anti-angiopoietin-like 4 antibody recapitulate the lipid phenotype found in angiopoietin-like 4 knockout mice
  65. Early Events in the Pathogenesis of Eastern Equine Encephalitis Virus in Mice
  66. Spontaneous Acute Tumor Lysis Syndrome in a DBA/1J Mouse: A Case Report and Review
  67. Cardiomyopathy Associated with Angiomatous Pheochromocytoma in a Rhesus Macaque (Macaca mulatta)
  68. Toxicity of the staphylococcal enterotoxin B mutants with histidine-to-tyrosine substitutions
  69. Determination of the virulence of the pigmentation-deficient and pigmentation-/plasminogen activator-deficient strains of Yersinia pestis in non-human primate and mouse models of pneumonic plague
  70. Mouse Model of Sublethal and Lethal Intraperitoneal Glanders (Burkholderia mallei)
  71. Characterization of a Multicopy Family of Genes Encoding a Surface-Expressed Serine Endoprotease in Rat Pneumocystis carinii
  72. The Hamster Model of Intraperitoneal Burkholderia mallei (Glanders)
  73. Comparative Neurovirulence and Tissue Tropism of Wild-type and Attenuated Strains of Venezuelan Equine Encephalitis Virus Administered by Aerosol in C3H/HeN and BALB/c Mice
  74. The agents of biological warfare
  75. Rapid Postmortem Invasion of Cecal Mucosa of Macaques by Nonpathogenic Entamoeba chattoni
  76. Aerosolized specific antibody protects mice from lung injury associated with aerosolized ricin exposure
  77. Expression of variants of the major surface glycoprotein of Pneumocystis carinii
  78. Neuroinvasion by simian immunodeficiency virus coincides with increased numbers of perivascular macrophages/microglia and intrathecal immune activation
  79. Evidence of Horizontal Transmission of Pneumocystis carinii Pneumonia in Simian Immunodeficiency Virus-Infected Rhesus Macaques
  80. Simian Immunodeficiency Virus Infection of Macaques: End-Stage Disease Is Characterized by Widespread Distribution of Proviral DNA in Tissues