All Stories

  1. Bacterial GtfB Augments Candida albicans Accumulation in Cross-Kingdom Biofilms

    Article • Journal of Dental Research, June 2017, SAGE Publications

    Hyun Koo

  2. Do catalytic nanoparticles offer an improved therapeutic strategy to combat dental biofilms?

    Article • Nanomedicine, February 2017, Future Medicine

    Hyun Koo

  3. l-Arginine Modifies the Exopolysaccharide Matrix and Thwarts Streptococcus mutans Outgrowth within Mixed-Species Oral Biofilms

    Article • Journal of Bacteriology, May 2016, ASM Journals

    Hyun Koo, Geelsu Hwang

  4. Streptococcus mutans Extracellular DNA Is Upregulated during Growth in Biofilms, Actively Released via Membrane Vesicles, and Influenced by Components of the Protein Secretion Machinery

    Article • Journal of Bacteriology, April 2014, ASM Journals

    Hyun Koo

  5. Symbiotic Relationship between Streptococcus mutans and Candida albicans Synergizes Virulence of Plaque BiofilmsIn Vivo

    Article • Infection and Immunity, February 2014, ASM Journals

    Hyun Koo

  6. Beyond Mucosal Infection: a Role for C. albicans-Streptococcal Interactions in the Pathogenesis of Dental Caries

    Article • Current Oral Health Reports, January 2014, Springer Science + Business Media

    Hyun Koo

  7. Effect of neovestitol–vestitol containing Brazilian red propolis on accumulation of biofilmin vitroand development of dental cariesin vivo

    Article • Biofouling, October 2013, Taylor & Francis

    Hyun Koo

  8. The Exopolysaccharide Matrix

    Article • Journal of Dental Research, September 2013, SAGE Publications

    Hyun Koo

  9. The specific degree-of-polymerization of A-type proanthocyanidin oligomers impactsStreptococcus mutansglucan-mediated adhesion and transcriptome responses within biofilms

    Article • Biofouling, July 2013, Taylor & Francis

    Hyun Koo

  10. Streptococcus mutans: a new Gram-positive paradigm?

    Article • Microbiology, February 2013, Society for General Microbiology

    Hyun Koo, Dr Jacqueline Abranches

  11. Streptococcus mutans Protein Synthesis during Mixed-Species Biofilm Development by High-Throughput Quantitative Proteomics

    Article • PLoS ONE, September 2012, PLOS

    Hyun Koo

  12. Novel Antibiofilm Chemotherapy Targets Exopolysaccharide Synthesis and Stress Tolerance in Streptococcus mutans To Modulate Virulence ExpressionIn Vivo

    Article • Antimicrobial Agents and Chemotherapy, September 2012, ASM Journals

    Hyun Koo

  13. Molecular approaches for viable bacterial population and transcriptional analyses in a rodent model of dental caries

    Article • Molecular Oral Microbiology, May 2012, Wiley

    Hyun Koo

  14. The Exopolysaccharide Matrix Modulates the Interaction between 3D Architecture and Virulence of a Mixed-Species Oral Biofilm

    Article • PLoS Pathogens, April 2012, PLOS

    Hyun Koo

  15. Role of Glucosyltransferase B in Interactions of Candida albicans with Streptococcus mutans and with an Experimental Pellicle on Hydroxyapatite Surfaces

    Article • Applied and Environmental Microbiology, July 2011, ASM Journals

    Hyun Koo

  16. Influences of trans‐trans farnesol, a membrane‐targeting sesquiterpenoid, on Streptococcus mutans physiology and survival within mixed‐species oral biofilms

    Article • International Journal of Oral Science, April 2011, Springer Science + Business Media

    Hyun Koo

  17. Elevated Incidence of Dental Caries in a Mouse Model of Cystic Fibrosis

    Article • PLoS ONE, January 2011, PLOS

    Hyun Koo

  18. An Analytical Tool-box for Comprehensive Biochemical, Structural and Transcriptome Evaluation of Oral Biofilms Mediated by Mutans Streptococci

    Article • Journal of Visualized Experiments, January 2011, MyJove Corporation

    Hyun Koo

  19. Biology of <i>Streptococcus mutans-</i>Derived Glucosyltransferases: Role in Extracellular Matrix Formation of Cariogenic Biofilms

    Article • Caries Research, January 2011, Karger Publishers

    Hyun Koo

  20. Natural Products in Caries Research: Current (Limited) Knowledge, Challenges and Future Perspective

    Article • Caries Research, January 2011, Karger Publishers

    Hyun Koo

  21. Human Common Salivary Protein 1 (CSP-1) Promotes Binding of Streptococcus mutans to Experimental Salivary Pellicle and Glucans Formed on Hydroxyapatite Surface

    Article • Journal of Proteome Research, October 2010, American Chemical Society (ACS)

    Hyun Koo

  22. Dynamics of Streptococcus mutans Transcriptome in Response to Starch and Sucrose during Biofilm Development

    Article • PLoS ONE, October 2010, PLOS

    Hyun Koo

  23. Inhibition ofStreptococcus mutansbiofilm accumulation and development of dental cariesin vivoby 7-epiclusianone and fluoride

    Article • Biofouling, September 2010, Taylor & Francis

    Hyun Koo

  24. Effects of 7-Epiclusianone on Streptococcus mutans and Caries Development in Rats

    Article • Planta Medica, July 2010, Thieme Publishing Group

    Hyun Koo

  25. A procedure for characterizing glucans synthesized by purified enzymes of cariogenic Streptococcus mutans

    Article • International Journal of Biological Macromolecules, June 2010, Elsevier

    Hyun Koo

  26. Exopolysaccharides Produced by Streptococcus mutans Glucosyltransferases Modulate the Establishment of Microcolonies within Multispecies Biofilms

    Article • Journal of Bacteriology, March 2010, ASM Journals

    Hyun Koo

  27. Protocols to Study the Physiology of Oral Biofilms

    Article • January 2010, Springer Science + Business Media

    Hyun Koo, Dr Jacqueline Abranches

  28. Influence of Cranberry Proanthocyanidins on Formation of Biofilms by <i>Streptococcus mutans</i> on Saliva-Coated Apatitic Surface and on Dental Caries Development in vivo

    Article • Caries Research, January 2010, Karger Publishers

    Hyun Koo

  29. Extracellular Polysaccharides Matrix — An Often Forgotten Virulence Factor in Oral Biofilm Research

    Article • International Journal of Oral Science, December 2009, Springer Science + Business Media

    Hyun Koo

  30. Structural organization and dynamics of exopolysaccharide matrix and microcolonies formation byStreptococcus mutansin biofilms

    Article • Journal of Applied Microbiology, November 2009, Oxford University Press (OUP)

    Hyun Koo

  31. Influences of naturally occurring agents in combination with fluoride on gene expression and structural organization of Streptococcus mutans in biofilms

    Article • BMC Microbiology, October 2009, Springer Science + Business Media

    Hyun Koo

  32. Naturally Occurring Molecules as Alternative Therapeutic Agents against Cariogenic Biofilms

    Article • Advances in Dental Research, July 2009, SAGE Publications

    Hyun Koo

  33. Adjunctive Chemotherapeutic Suppression of Mutans Streptococci in the Setting of Severe Early Childhood Caries: An Exploratory Study

    Article • Journal of Public Health Dentistry, June 2009, Wiley

    Hyun Koo

  34. Role of Clp Proteins in Expression of Virulence Properties of Streptococcus mutans

    Article • Journal of Bacteriology, January 2009, ASM Journals

    Hyun Koo

  35. Structural and Molecular Basis of the Role of Starch and Sucrose in Streptococcus mutans Biofilm Development

    Article • Applied and Environmental Microbiology, November 2008, ASM Journals

    Hyun Koo

  36. Antimicrobial activity of Rheedia brasiliensis and 7-epiclusianone against Streptococcus mutans

    Article • Phytomedicine, October 2008, Elsevier

    Hyun Koo

  37. Isolation and purification of total RNA from Streptococcus mutans in suspension cultures and biofilms

    Article • Brazilian Oral Research, September 2008, FapUNIFESP (SciELO)

    Hyun Koo

  38. Strategies to Enhance the Biological Effects of Fluoride on Dental Biofilms

    Article • Advances in Dental Research, July 2008, SAGE Publications

    Hyun Koo

  39. Influences of starch and sucrose on Streptococcus mutans biofilms

    Article • Oral Microbiology and Immunology, April 2008, Wiley

    Hyun Koo

  40. Inhibitory effects of 7-epiclusianone on glucan synthesis, acidogenicity and biofilm formation by Streptococcus mutans

    Article • FEMS Microbiology Letters, April 2008, Oxford University Press (OUP)

    Hyun Koo

  41. Effect of Starch and Sucrose on Dental Biofilm Formation and on Root Dentine Demineralization

    Article • Caries Research, January 2008, Karger Publishers

    Hyun Koo

  42. Effects of Sucrose on the Extracellular Matrix of Plaque-Like Biofilm Formed in vivo, Studied by Proteomic Analysis

    Article • Caries Research, January 2008, Karger Publishers

    Hyun Koo

  43. Chemical Characterization of Red Wine Grape (Vitis viniferaandVitisInterspecific Hybrids) and Pomace Phenolic Extracts and Their Biological Activity againstStreptococcus mutans

    Article • Journal of Agricultural and Food Chemistry, November 2007, American Chemical Society (ACS)

    Hyun Koo

  44. Influence of cranberry phenolics on glucan synthesis by glucosyltransferases and Streptococcus mutans acidogenicity

    Article • Journal of Applied Microbiology, June 2007, Oxford University Press (OUP)

    Hyun Koo

  45. Extraction and purification of total RNA from Sreptococcus mutans biofilms

    Article • Analytical Biochemistry, June 2007, Elsevier

    Hyun Koo

  46. Role of Unsaturated Fatty Acid Biosynthesis in Virulence of Streptococcus mutans

    Article • Infection and Immunity, January 2007, ASM Journals

    Hyun Koo, Elizabeth M. Fozo

  47. The Role of Sucrose in Cariogenic Dental Biofilm Formation—New Insight

    Article • Journal of Dental Research, October 2006, SAGE Publications

    Hyun Koo

  48. Inhibitory effects of cranberry polyphenols on formation and acidogenicity of Streptococcus mutans biofilms

    Article • FEMS Microbiology Letters, April 2006, Oxford University Press (OUP)

    Hyun Koo

  49. Influence of Apigenin on gtf Gene Expression in Streptococcus mutans UA159

    Article • Antimicrobial Agents and Chemotherapy, February 2006, ASM Journals

    Hyun Koo, Dr Jacqueline Abranches

  50. The influence of a novel propolis on mutans streptococci biofilms and caries development in rats

    Article • Archives of Oral Biology, January 2006, Elsevier

    Hyun Koo

  51. Co-operative inhibition by fluoride and zinc of glucosyl transferase production and polysaccharide synthesis by mutans streptococci in suspension cultures and biofilms

    Article • FEMS Microbiology Letters, January 2006, Oxford University Press (OUP)

    Hyun Koo

  52. Influence of Cranberry Juice on Glucan-Mediated Processes Involved in <i>Streptococcus mutans </i>Biofilm Development

    Article • Caries Research, December 2005, Karger Publishers

    Hyun Koo

  53. Effect of Sucrose Concentration on Dental Biofilm Formed in situ and on Enamel Demineralization

    Article • Caries Research, December 2005, Karger Publishers

    Hyun Koo

  54. Apigenin andtt-Farnesol with Fluoride Effects onS. mutansBiofilms and Dental Caries

    Article • Journal of Dental Research, November 2005, SAGE Publications

    Hyun Koo

  55. In vitro and in vivo effects of isolated fractions of Brazilian propolis on caries development

    Article • Journal of Ethnopharmacology, October 2005, Elsevier

    Hyun Koo

  56. Interactions of <i>Streptococcus mutans</i> Glucosyltransferase B with Lysozyme in Solution and on the Surface of Hydroxyapatite

    Article • Caries Research, January 2005, Karger Publishers

    Hyun Koo

  57. Inhibition of Streptococcus mutans biofilm accumulation and polysaccharide production by apigenin and tt-farnesol

    Article • Journal of Antimicrobial Chemotherapy, September 2003, Oxford University Press (OUP)

    Hyun Koo

  58. Effects of Fluoride and Aluminum from Ionomeric Materials on S. mutans Biofilm

    Article • Journal of Dental Research, April 2003, SAGE Publications

    Hyun Koo

  59. Effects of apigenin and tt‐farnesol on glucosyltransferase activity, biofilm viability and caries development in rats

    Article • Oral Microbiology and Immunology, December 2002, Wiley

    Hyun Koo

  60. Effects of Compounds Found in Propolis on Streptococcus mutans Growth and on Glucosyltransferase Activity

    Article • Antimicrobial Agents and Chemotherapy, May 2002, ASM Journals

    Hyun Koo

  61. Effect of a Mouthrinse Containing Selected Propolis on 3-Day Dental Plaque Accumulation and Polysaccharide Formation

    Article • Caries Research, January 2002, Karger Publishers

    Hyun Koo

  62. Effects of <i>Apis mellifera</i> Propolis on the Activities of Streptococcal Glucosyltransferases in Solution and Adsorbed onto Saliva–Coated Hydroxyapatite

    Article • Caries Research, January 2000, Karger Publishers

    Hyun Koo

  63. Avaliação in situ de um dentifrício contendo MFP/DCPD na incorporação de flúor e remineralização do esmalte dental humano

    Article • Revista de Odontologia da Universidade de São Paulo, July 1999, FapUNIFESP (SciELO)

    Hyun Koo

  64. Effect of Apis mellifera Propolis from Two Brazilian Regions on Caries Development in Desalivated Rats

    Article • Caries Research, January 1999, Karger Publishers

    Hyun Koo