All Stories

  1. Metagenomic evidence for taxonomic dysbiosis and functional imbalance in the gastrointestinal tracts of children with cystic fibrosis

    Article • Scientific Reports, March 2016, Nature

    Dr Lucas Hoffman

  2. SCV S. aureus antibiotic susceptibility testing

    Article • Antimicrobial Agents and Chemotherapy, January 2016, ASM Journals

    Dr Lucas Hoffman

  3. Implications of multiple freeze-thawing on respiratory samples for culture-independent analyses

    Article • Journal of Cystic Fibrosis, July 2015, Elsevier

    Professor Julian Parkhill, Dr Lucas Hoffman

  4. The pediatric microbiome and the lung

    Article • Current Opinion in Pediatrics, June 2015, Wolters Kluwer Health

    Dr Lucas Hoffman

  5. Emerging drugs for bronchiectasis: an update

    Article • Expert Opinion on Emerging Drugs, March 2015, Informa Healthcare

    Dr Lucas Hoffman

  6. Cystic fibrosis mouse model-dependent intestinal structure and gut microbiome

    Article • Mammalian Genome, February 2015, Springer Science + Business Media

    Dr Lucas Hoffman

  7. Toward Making Inroads in Reducing the Disparity of Lung Health in Australian Indigenous and New Zealand Māori Children

    Article • Frontiers in Pediatrics, February 2015, Frontiers

    Dr Lucas Hoffman

  8. Narrowing in on Early Cystic Fibrosis Lung Disease

    Article • American Review of Respiratory Disease, November 2014, American Thoracic Society

    Dr Lucas Hoffman, Edith Zemanick

  9. Strength in Diversity

    Article • Cell Host & Microbe, October 2014, Elsevier

    Dr Lucas Hoffman

  10. Three Clinically Distinct Chronic Pediatric Airway Infections Share a Common Core Microbiota

    Article • Annals of the American Thoracic Society, September 2014, American Thoracic Society

    Dr Lucas Hoffman

  11. Directly Sampling the Lung of a Young Child with Cystic Fibrosis Reveals Diverse Microbiota

    Article • Annals of the American Thoracic Society, September 2014, American Thoracic Society

    Dr Lucas Hoffman

  12. Pseudomonas aeruginosa in vitroPhenotypes Distinguish Cystic Fibrosis Infection Stages and Outcomes

    Article • American Review of Respiratory Disease, June 2014, American Thoracic Society

    Dr Lucas Hoffman

  13. Gastrointestinal Pathology in Juvenile and Adult CFTR-Knockout Ferrets

    Article • American Journal Of Pathology, May 2014, Elsevier

    Dr Lucas Hoffman

  14. Evaluation of Microbial Bacterial and Fungal Diversity in Cerebrospinal Fluid Shunt Infection

    Article • PLoS ONE, January 2014, PLOS

    Dr Lucas Hoffman

  15. Interpreting infective microbiota: the importance of an ecological perspective

    Article • Trends in Microbiology, June 2013, Elsevier

    Dr Lucas Hoffman

  16. What to Expect When You’re Expectorating: Cystic Fibrosis Exacerbations and Microbiota

    Article • Annals of the American Thoracic Society, June 2013, American Thoracic Society

    Dr Lucas Hoffman

  17. Cystic Fibrosis Therapeutics

    Article • CHEST Journal, January 2013, Elsevier

    Dr Lucas Hoffman

  18. Reducing bias in bacterial community analysis of lower respiratory infections

    Article • The ISME Journal, November 2012, Oxford University Press (OUP)

    Dr Lucas Hoffman

  19. Emerging drugs for bronchiectasis

    Article • Expert Opinion on Emerging Drugs, July 2012, Informa Healthcare

    Dr Lucas Hoffman

  20. Novel concepts in evaluating antimicrobial therapy for bacterial lung infections in patients with cystic fibrosis

    Article • Journal of Cystic Fibrosis, December 2011, Elsevier

    Dr Lucas Hoffman

  21. Does bacterial density in cystic fibrosis sputum increase prior to pulmonary exacerbation?

    Article • Journal of Cystic Fibrosis, September 2011, Elsevier

    Dr Lucas Hoffman

  22. Using bacterial biomarkers to identify early indicators of cystic fibrosis pulmonary exacerbation onset

    Article • Expert Review of Molecular Diagnostics, March 2011, Taylor & Francis

    Dr Lucas Hoffman

  23. Failure to Recover to Baseline Pulmonary Function after Cystic Fibrosis Pulmonary Exacerbation

    Article • American Review of Respiratory Disease, September 2010, American Thoracic Society

    Dr Lucas Hoffman

  24. Revealing the dynamics of polymicrobial infections: implications for antibiotic therapy

    Article • Trends in Microbiology, August 2010, Elsevier

    Dr Lucas Hoffman

  25. Nutrient Availability as a Mechanism for Selection of Antibiotic Tolerant Pseudomonas aeruginosa within the CF Airway

    Article • PLoS Pathogens, January 2010, PLOS

    Professor Ferric C Fang, Dr Lucas Hoffman

  26. Return of FEV1 after pulmonary exacerbation in children with cystic fibrosis

    Article • Pediatric Pulmonology, January 2010, Wiley

    Dr Lucas Hoffman

  27. Management of children with empyema: Pleural drainage is not always necessary

    Article • Pediatric Pulmonology, January 2010, Wiley

    Dr Lucas Hoffman

  28. Erratum: Return of FEV1after pulmonary exacerbation in children with cystic fibrosis

    Article • Pediatric Pulmonology, January 2010, Wiley

    Dr Lucas Hoffman

  29. Pseudomonas aeruginosa lasR mutants are associated with cystic fibrosis lung disease progression

    Article • Journal of Cystic Fibrosis, January 2009, Elsevier

    Dr Lucas Hoffman

  30. Growth phenotypes of Pseudomonas aeruginosa lasR mutants adapted to the airways of cystic fibrosis patients

    Article • Molecular Microbiology, April 2007, Wiley

    Prof Eric Déziel, Dr Lucas Hoffman, Dr Robert Ernst

  31. Did Bacterial Sensing of Host Environments Evolve from Sensing within Microbial Communities?

    Article • Cell Host & Microbe, April 2007, Elsevier

    Dr Lucas Hoffman

  32. Lipoid Pneumonia Due to Mexican Folk Remedies

    Article • Archives of Pediatrics and Adolescent Medicine, November 2005, American Medical Association (AMA)

    Dr Lucas Hoffman

  33. Aminoglycoside antibiotics induce bacterial biofilm formation

    Article • August 2005, Nature

    Dr Lucas Hoffman

  34. Specific Single or Double Proline Substitutions in the “Spring-loaded” Coiled-Coil Region of the Influenza Hemagglutinin Impair or Abolish Membrane Fusion Activity

    Article • The Journal of Cell Biology, June 1998, Rockefeller University Press

    Dr Lucas Hoffman

  35. The discovery, characterization and crystallographically determined binding mode of an FMOC-containing inhibitor of HIV-1 protease

    Article • Bioorganic & Medicinal Chemistry, July 1997, Elsevier

    Dr Lucas Hoffman