All Stories

  1. Soluble p75 neurotrophic receptor as a reliable biomarker in neurodegenerative diseases: what is the evidence?

    Article • Neural Regeneration Research, July 2023, Medknow

    Dr Marie Lordkipanidzé

  2. Consensus report on flow cytometry for platelet function testing in thrombocytopenic patients: communication from the SSC of the ISTH

    Article • Journal of Thrombosis and Haemostasis, July 2023, Elsevier

    Dr Marie Lordkipanidzé

  3. Assessment of Platelet Function by High-Throughput Screening Light Transmission Aggregometry: Optimul Assay

    Article • January 2023, Springer Science + Business Media

    Dr Marie Lordkipanidzé

  4. Plasminogen Activator Inhibitor-1–Positive Platelet-Derived Extracellular Vesicles Predicts MACE and the Proinflammatory SMC Phenotype

    Article • JACC Basic to Translational Science, October 2022, Elsevier

    Dr Marie Lordkipanidzé

  5. Expert opinion on the use of platelet secretion assay for the diagnosis of inherited platelet function disorders: Communication from the ISTH SSC Subcommittee on Platelet Physiology

    Article • Journal of Thrombosis and Haemostasis, June 2022, Wiley

    Dr Marie Lordkipanidzé

  6. Antiplatelet Therapy in Atherothrombotic Diseases: Similarities and Differences Across Guidelines

    Article • Frontiers in Pharmacology, April 2022, Frontiers

    Dr Marie Lordkipanidzé

  7. Assessing cardiometabolic parameter monitoring in inpatients taking a second-generation antipsychotic: The CAMI-SGA study – a cross-sectional study

    Article • BMJ Open, April 2022, BMJ

    Dr Marie Lordkipanidzé

  8. Aspirin for Primary Cardiovascular Prevention in Patients with Diabetes: Uncertainties and Opportunities

    Article • Thrombosis and Haemostasis, March 2022, Thieme Publishing Group

    Dr Marie Lordkipanidzé

  9. Clinical Correlates Identify ProBDNF and Thrombo-Inflammatory Markers as Key Predictors of Circulating p75NTR Extracellular Domain Levels in Older Adults

    Article • Frontiers in Aging Neuroscience, February 2022, Frontiers

    Dr Marie Lordkipanidzé

  10. Rare missense variants in Tropomyosin‐4 (TPM4) are associated with platelet dysfunction, cytoskeletal defects, and excessive bleeding

    Article • Journal of Thrombosis and Haemostasis, February 2022, Elsevier

    Dr Marie Lordkipanidzé

  11. Editorial: Established and Novel Roles of Platelets in Health and Disease

    Article • Frontiers in Cardiovascular Medicine, January 2022, Frontiers

    Dr Marie Lordkipanidzé

  12. Antiplatelet Therapy for Atherothrombotic Disease in 2022—From Population to Patient-Centered Approaches

    Article • Frontiers in Cardiovascular Medicine, January 2022, Frontiers

    Dr Marie Lordkipanidzé

  13. A randomized double-blind feasibility study comparing cetirizine and diphenhydramine in the prevention of paclitaxel-associated infusion-related reactions: the PREMED-F1 study

    Article • Supportive Care in Cancer, January 2022, Springer Science + Business Media

    Dr Marie Lordkipanidzé

  14. Current and Novel Antiplatelet Therapies for the Treatment of Cardiovascular Diseases

    Article • International Journal of Molecular Sciences, December 2021, MDPI AG

    Dr Marie Lordkipanidzé

  15. Consensus recommendations on flow cytometry for the assessment of inherited and acquired disorders of platelet number and function: Communication from the ISTH SSC Subcommittee on Platelet Physiology

    Article • Journal of Thrombosis and Haemostasis, September 2021, Wiley

    Dr Marie Lordkipanidzé

  16. Differences in platelet‐rich plasma composition influence bone healing

    Article • Journal Of Clinical Periodontology, September 2021, Wiley

    Dr Marie Lordkipanidzé

  17. The brain-derived neurotrophic factor prompts platelet aggregation and secretion

    Article • Blood Advances, September 2021, American Society of Hematology

    Dr Marie Lordkipanidzé

  18. Brain-Derived Neurotrophic Factor Mitigates the Association Between Platelet Dysfunction and Cognitive Impairment

    Article • Frontiers in Cardiovascular Medicine, September 2021, Frontiers

    Dr Marie Lordkipanidzé

  19. Effect of Paper Versus Digital Reading in Health Professional Education: A Systematic Review and Meta-Analysis

    Article • American Journal of Pharmaceutical Education, July 2021, American Journal of Pharmaceutical Education

    Dr Marie Lordkipanidzé

  20. The effect of aging on the bone healing properties of blood plasma

    Article • Injury, July 2021, Elsevier

    Dr Marie Lordkipanidzé

  21. Differential modulation of polyunsaturated fatty acids in patients with myocardial infarction treated with ticagrelor or clopidogrel

    Article • Cell Reports Medicine, June 2021, Elsevier

    Dr Marie Lordkipanidzé

  22. The ISTH bleeding assessment tool as predictor of bleeding events in inherited platelet disorders: Communication from the ISTH SSC Subcommittee on Platelet Physiology

    Article • Journal of Thrombosis and Haemostasis, May 2021, Elsevier

    Dr Marie Lordkipanidzé

  23. Dual antiplatelet therapy (PEGASUS) vs. dual pathway (COMPASS): a head-to-head in vitro comparison

    Article • Platelets, April 2021, Taylor & Francis

    Dr Marie Lordkipanidzé

  24. Platelet Function in Viral Immunity and SARS-CoV-2 Infection

    Article • Seminars in Thrombosis and Hemostasis, April 2021, Thieme Publishing Group

    Dr Marie Lordkipanidzé

  25. Platelet Quiescence in Patients With Acute Coronary Syndrome Undergoing Coronary Artery Bypass Graft Surgery

    Article • Journal of the American Heart Association, February 2021, Wolters Kluwer Health

    Dr Marie Lordkipanidzé

  26. Tissue-Specificity of Antibodies Raised Against TrkB and p75NTR Receptors; Implications for Platelets as Models of Neurodegenerative Diseases

    Article • Frontiers in Immunology, February 2021, Frontiers

    Dr Marie Lordkipanidzé

  27. Severity of Megakaryocyte‐Driven Osteosclerosis in Mpig6b ‐Deficient Mice Is Sex‐Linked

    Article • Journal of Bone and Mineral Research, February 2021, Wiley

    Dr Marie Lordkipanidzé

  28. Acetylcholinesterase inhibitors and risk of bleeding and acute ischemic events in non‐hypertensive Alzheimer's patients

    Article • Alzheimer s & Dementia Translational Research & Clinical Interventions, January 2021, Wiley

    Dr Marie Lordkipanidzé

  29. Implications of the Antiplatelet Therapy Gap Left with Discontinuation of Prasugrel in Canada

    Article • CJC Open, December 2020, Elsevier

    Dr Marie Lordkipanidzé

  30. Platelets Selectively Regulate the Release of BDNF, But Not That of Its Precursor Protein, proBDNF

    Article • Frontiers in Immunology, November 2020, Frontiers

    Dr Marie Lordkipanidzé

  31. Postoperative Administration of the Acetylcholinesterase Inhibitor, Donepezil, Interferes with Bone Healing and Implant Osseointegration in a Rat Model

    Article • Biomolecules, September 2020, MDPI AG

    Dr Marie Lordkipanidzé

  32. Advances in Platelet Function Testing—Light Transmission Aggregometry and Beyond

    Article • Journal of Clinical Medicine, August 2020, MDPI AG

    Dr Marie Lordkipanidzé

  33. Platelet count and disease – editorial policy

    Article • Platelets, August 2020, Taylor & Francis

    Dr Marie Lordkipanidzé

  34. Effects of reading media on reading comprehension in health professional education

    Article • JBI Evidence Synthesis, July 2020, Wolters Kluwer Health

    Dr Marie Lordkipanidzé

  35. Differential correlation of serum BDNF and microRNA content in rats with rapid or late onset of heavy alcohol use

    Article • Addiction Biology, March 2020, Wiley

    Dr Marie Lordkipanidzé

  36. Head-to-Head Comparison of Consensus-Recommended Platelet Function Tests to Assess P2Y12 Inhibition—Insights for Multi-Center Trials

    Article • Journal of Clinical Medicine, January 2020, MDPI AG

    Dr Marie Lordkipanidzé

  37. Differential Correlation of Serum BDNF and microRNA Content in Rats with Rapid or Late Onset of Heavy Alcohol Use

    Article • December 2019, Cold Spring Harbor Laboratory Press

    Dr Marie Lordkipanidzé

  38. Validation of the ISTH/SSC bleeding assessment tool for inherited platelet disorders: A communication from the Platelet Physiology SSC

    Article • Journal of Thrombosis and Haemostasis, December 2019, Wiley

    Dr Marie Lordkipanidzé, Marie-Christine Morel-Kopp

  39. A Critical Comparison of Canadian and International Guidelines Recommendations for Antiplatelet Therapy in Coronary Artery Disease

    Article • Canadian Journal of Cardiology, December 2019, Elsevier

    Dr Marie Lordkipanidzé

  40. Platelet Function in Aging

    Article • Frontiers in Cardiovascular Medicine, August 2019, Frontiers

    Dr Marie Lordkipanidzé

  41. Study of the bioaccumulation of tinzaparin in renally impaired patients when given at prophylactic doses - The STRIP study

    Article • Thrombosis Research, February 2019, Elsevier

    Dr Marie Lordkipanidzé

  42. Clinical Tests of Platelet Function

    Article • January 2019, Elsevier

    Dr Marie Lordkipanidzé

  43. 750

    Article • Critical Care Medicine, January 2019, Wolters Kluwer Health

    Dr Marie Lordkipanidzé

  44. Increased platelet reactivity and platelet–leukocyte aggregation after elective coronary bypass surgery

    Article • Platelets, November 2018, Taylor & Francis

    Dr Marie Lordkipanidzé

  45. An interview with Professor Gus Born

    Article • Platelets, October 2018, Taylor & Francis

    Dr Marie Lordkipanidzé

  46. Clinical importance of thrombocytopenia in patients with acute coronary syndromes: a systematic review and meta-analysis

    Article • Platelets, October 2018, Taylor & Francis

    Dr Marie Lordkipanidzé

  47. 2018 Canadian Cardiovascular Society/Canadian Association of Interventional Cardiology Focused Update of the Guidelines for the Use of Antiplatelet Therapy

    Article • Canadian Journal of Cardiology, March 2018, Elsevier

    Dr Marie Lordkipanidzé

  48. Platelets at the heart of therapy

    Article • Platelets, February 2018, Taylor & Francis

    Dr Marie Lordkipanidzé

  49. Ischemic and bleeding outcomes after coronary artery bypass grafting among patients initially treated with a P2Y12 receptor antagonist for acute coronary syndromes: Insights on timing of discontinuation of ticagrelor and clopidogrel prior to surgery

    Article • European Heart Journal Acute Cardiovascular Care, January 2018, SAGE Publications

    Dr Marie Lordkipanidzé

  50. Personalizing antiplatelet therapies: What have we learned from recent trials?

    Article • Platelets, June 2017, Taylor & Francis

    Dr Marie Lordkipanidzé

  51. Tailored antiplatelet therapy in high-risk ACS patients treated with PCI stenting: lessons from the ANTARCTIC trial

    Article • Journal of Thoracic Disease, May 2017, AME Publishing Company

    Dr Marie Lordkipanidzé

  52. Mice Lacking the Inhibitory Collagen Receptor LAIR-1 Exhibit a Mild Thrombocytosis and Hyperactive PlateletsHighlights

    Article • Arteriosclerosis Thrombosis and Vascular Biology, March 2017, Wolters Kluwer Health

    Dr Marie Lordkipanidzé

  53. PREVALENCE AND CLINICAL IMPACT OF THROMBOCYTOPENIA IN PATIENTS WITH ACUTE CORONARY SYNDROMES: A SYSTEMATIC REVIEW AND META-ANALYSIS

    Article • Journal of the American College of Cardiology, March 2017, Elsevier

    Dr Marie Lordkipanidzé

  54. Platelet function one and three months after coronary bypass surgery in relation to once or twice daily dosing of acetylsalicylic acid

    Article • Thrombosis Research, January 2017, Elsevier

    Dr Marie Lordkipanidzé

  55. Platelet Function Tests

    Article • January 2017, Springer Science + Business Media

    Dr Marie Lordkipanidzé

  56. Tests of Platelet Function

    Article • November 2016, Wiley

    Dr Marie Lordkipanidzé

  57. ISCHEMIC AND BLEEDING OUTCOMES AFTER CORONARY ARTERY BYPASS GRAFTING AMONG PATIENTS INITIALLY TREATED WITH A P2Y12 RECEPTOR ANTAGONIST FOR ACUTE CORONARY SYNDROMES - INSIGHTS ON THE USE OF TICAGRELOR VERSUS CLOPIDOGREL PRIOR TO SURGERY

    Article • Canadian Journal of Cardiology, October 2016, Elsevier

    Dr Marie Lordkipanidzé

  58. ISCHEMIC AND BLEEDING OUTCOMES AFTER CORONARY ARTERY BYPASS GRAFTING AMONG PATIENTS INITIALLY TREATED WITH A P2Y12 RECEPTOR ANTAGONIST FOR ACUTE CORONARY SYNDROMES - INSIGHTS ON TIMING OF DISCONTINUATION OF TICAGRELOR AND CLOPIDOGREL PRIOR TO SURGERY

    Article • Canadian Journal of Cardiology, October 2016, Elsevier

    Dr Marie Lordkipanidzé

  59. The Effects of Different Aspirin Dosing Frequencies and the Timing of Aspirin Intake in Primary and Secondary Prevention of Cardiovascular Disease: A Systematic Review

    Article • Clinical Pharmacology & Therapeutics, September 2016, Wiley

    Dr Marie Lordkipanidzé

  60. Platelet function testing as a biomarker for efficacy of antiplatelet drugs

    Article • Biomarkers in Medicine, August 2016, Future Medicine

    Dr Marie Lordkipanidzé

  61. Whole exome sequencing identifies genetic variants in inherited thrombocytopenia with secondary qualitative function defects

    Article • Haematologica, June 2016, Ferrata Storti Foundation (Haematologica)

    Dr Marie Lordkipanidzé

  62. Platelet function tests

    Article • Seminars in Thrombosis and Hemostasis, February 2016, Thieme Publishing Group

    Dr Marie Lordkipanidzé

  63. Vorapaxar and diplopia: Possible off-target PAR-receptor mismodulation

    Article • Thrombosis and Haemostasis, February 2016, Schattauer GmbH

    Dr Marie Lordkipanidzé

  64. Is platelet transfusion the solution to reverse platelet inhibition in patients on triple antiplatelet therapy?

    Article • Thrombosis Research, December 2015, Elsevier

    Dr Marie Lordkipanidzé

  65. SLFN14 mutations underlie thrombocytopenia with excessive bleeding and platelet secretion defects

    Article • Journal of Clinical Investigation, August 2015, American Society for Clinical Investigation

    Dr Marie Lordkipanidzé

  66. The role of platelets in the recruitment of leukocytes during vascular disease

    Article • Platelets, July 2015, Taylor & Francis

    Dr Marie Lordkipanidzé, Matthew Harrison

  67. Investigating the effectiveness of different aspirin dosing regimens and the timing of aspirin intake in primary and secondary prevention of cardiovascular disease: protocol for a systematic review

    Article • Systematic Reviews, June 2015, Springer Science + Business Media

    Dr Marie Lordkipanidzé

  68. Impact of preoperative use of P2Y12 receptor inhibitors on clinical outcomes in cardiac and non-cardiac surgery: A systematic review and meta-analysis

    Article • European Heart Journal Acute Cardiovascular Care, May 2015, SAGE Publications

    Professor Jolanta M Siller-Matula, Dr Marie Lordkipanidzé

  69. The prognostic utility of tests of platelet function for the detection of ‘aspirin resistance’ in patients with established cardiovascular or cerebrovascular disease: a systematic review and economic evaluation

    Article • Health Technology Assessment, May 2015, National Institute for Health Research

    Dr Marie Lordkipanidzé

  70. Use of next‐generation sequencing and candidate gene analysis to identify underlying defects in patients with inherited platelet function disorders

    Article • Journal of Thrombosis and Haemostasis, January 2015, Wiley

    Dr Marie Lordkipanidzé

  71. Diversity and impact of rare variants in genes encoding the platelet G protein-coupled receptors

    Article • Thrombosis and Haemostasis, January 2015, Schattauer GmbH

    Dr Marie Lordkipanidzé

  72. Methodological issues and recommendations for systematic reviews of prognostic studies: an example from cardiovascular disease

    Article • Systematic Reviews, December 2014, Springer Science + Business Media

    Dr Marie Lordkipanidzé

  73. Evidence of platelet sensitization to ADP following discontinuation of clopidogrel therapy in patients with stable coronary artery disease

    Article • Platelets, August 2014, Informa Healthcare

    Dr Marie Lordkipanidzé

  74. A novel mutation in the P2Y12 receptor and a function‐reducing polymorphism in protease‐activated receptor 1 in a patient with chronic bleeding

    Article • Journal of Thrombosis and Haemostasis, May 2014, Elsevier

    Dr Marie Lordkipanidzé

  75. Evaluation of a whole blood remote platelet function test for the diagnosis of mild bleeding disorders

    Article • Journal of Thrombosis and Haemostasis, May 2014, Wiley

    Dr Marie Lordkipanidzé

  76. Characterization of multiple platelet activation pathways in patients with bleeding as a high-throughput screening option: use of 96-well Optimul assay

    Article • Blood, January 2014, American Society of Hematology

    Dr Marie Lordkipanidzé

  77. A novel thromboxane A2 receptor N42S variant results in reduced surface expression and platelet dysfunction

    Article • Thrombosis and Haemostasis, January 2014, Schattauer GmbH

    Dr Marie Lordkipanidzé

  78. Enrichment of FLI1 and RUNX1 mutations in families with excessive bleeding and platelet dense granule secretion defects

    Article • Blood, October 2013, American Society of Hematology

    Dr Marie Lordkipanidzé

  79. Utility of the ISTH bleeding assessment tool in predicting platelet defects in participants with suspected inherited platelet function disorders

    Article • Journal of Thrombosis and Haemostasis, September 2013, Wiley

    Dr Marie Lordkipanidzé

  80. Pharmacogenomics in cardiovascular disease: focus on aspirin and ADP receptor antagonists

    Article • Journal of Thrombosis and Haemostasis, September 2013, Wiley

    Dr Marie Lordkipanidzé

  81. Genotyping and phenotyping of platelet function disorders

    Article • Journal of Thrombosis and Haemostasis, June 2013, Elsevier

    Dr Marie Lordkipanidzé

  82. Testing Platelet Function

    Article • Hematology/Oncology Clinics of North America, June 2013, Elsevier

    Dr Marie Lordkipanidzé

  83. Simultaneous measurement of ATP release and LTA does not potentiate platelet aggregation to epinephrine

    Article • Thrombosis and Haemostasis, May 2013, Schattauer GmbH

    Dr Marie Lordkipanidzé

  84. Microsatellite markers as a rapid approach for autozygosity mapping in Hermansky-Pudlak syndrome: Identification of the second HPS7 mutation in a patient presenting late in life

    Article • Thrombosis and Haemostasis, January 2013, Schattauer GmbH

    Dr Marie Lordkipanidzé

  85. OC-13 Investigation of underlying platelet function defects in patients with unexplained menorrhagia

    Article • Thrombosis Research, January 2013, Elsevier

    Dr Marie Lordkipanidzé

  86. Protocol for a systematic review of the diagnostic and prognostic utility of tests currently available for the detection of aspirin resistance in patients with established cardiovascular or cerebrovascular disease

    Article • Systematic Reviews, January 2013, Springer Science + Business Media

    Dr Marie Lordkipanidzé

  87. Clinical Tests of Platelet Function

    Article • January 2013, Elsevier

    Dr Marie Lordkipanidzé

  88. G6f-Like Is an ITAM-Containing Collagen Receptor in Thrombocytes

    Article • PLoS ONE, December 2012, PLOS

    Dr Marie Lordkipanidzé

  89. Platelet Turnover in Atherothrombotic Disease

    Article • Current Pharmaceutical Design, September 2012, Bentham Science Publishers

    Dr Marie Lordkipanidzé

  90. Evaluation of participants with suspected heritable platelet function disorders including recommendation and validation of a streamlined agonist panel

    Article • Blood, September 2012, American Society of Hematology

    Dr Marie Lordkipanidzé

  91. Advances in monitoring of aspirin therapy

    Article • Platelets, August 2012, Taylor & Francis

    Dr Marie Lordkipanidzé

  92. Aspirin twice a day keeps new COX-1 at bay

    Article • Journal of Thrombosis and Haemostasis, July 2012, Wiley

    Dr Marie Lordkipanidzé

  93. 50th anniversary of the discovery of ibuprofen: an interview with Dr Stewart Adams

    Article • Platelets, November 2011, Taylor & Francis

    Dr Marie Lordkipanidzé

  94. Genetic determinants of response to aspirin: Appraisal of 4 candidate genes

    Article • Thrombosis Research, July 2011, Elsevier

    Dr Marie Lordkipanidzé

  95. Heterogeneity in platelet cyclooxygenase inhibition by aspirin in coronary artery disease

    Article • International Journal of Cardiology, July 2011, Elsevier

    Dr Marie Lordkipanidzé

  96. Beware of being caught on the rebound

    Article • Journal of Thrombosis and Haemostasis, January 2011, Wiley

    Dr Marie Lordkipanidzé

  97. Why an aspirin a day no longer keeps the doctor away …

    Article • Thrombosis and Haemostasis, December 2010, Schattauer GmbH

    Dr Marie Lordkipanidzé

  98. Platelet count, not oxidative stress, may contribute to inadequate platelet inhibition by aspirin

    Article • International Journal of Cardiology, August 2010, Elsevier

    Dr Marie Lordkipanidzé

  99. Insights into the interpretation of light transmission aggregometry for evaluation of platelet aggregation inhibition by clopidogrel

    Article • Thrombosis Research, November 2009, Elsevier

    Dr Marie Lordkipanidzé

  100. Prevalence of Unresponsiveness to Aspirin and/or Clopidogrel in Patients With Stable Coronary Heart Disease

    Article • The American Journal of Cardiology, November 2009, Elsevier

    Dr Marie Lordkipanidzé

  101. Evaluation of the platelet count drop method for assessment of platelet function in comparison with “gold standard” light transmission aggregometry

    Article • Thrombosis Research, September 2009, Elsevier

    Dr Marie Lordkipanidzé

  102. Week-Long High-Maintenance Dose Clopidogrel Regimen Achieves Better Platelet Aggregation Inhibition than a Standard Loading Dose before Percutaneous Coronary Intervention: Results of a Double-Blind, Randomized Clinical Trial

    Article • Journal of Interventional Cardiology, August 2009, Wiley

    Dr Marie Lordkipanidzé

  103. Possibility of a rebound phenomenon following antiplatelet therapy withdrawal: A look at the clinical and pharmacological evidence

    Article • Pharmacology & Therapeutics, August 2009, Elsevier

    Dr Marie Lordkipanidzé

  104. Response to aspirin in healthy individuals. Cross-comparison of light transmission aggregometry, VerifyNow system, platelet count drop, thromboelastography (TEG) and urinary 11-dehydrothromboxane B2

    Article • Thrombosis and Haemostasis, May 2009, Schattauer GmbH

    Dr Marie Lordkipanidzé

  105. Comparison of four tests to assess inhibition of platelet function by clopidogrel in stable coronary artery disease patients

    Article • European Heart Journal, October 2008, European Society of Cardiology

    Dr Marie Lordkipanidzé

  106. Assessment of VerifyNow P2Y12 Assay Accuracy in Evaluating Clopidogrel-Induced Platelet Inhibition

    Article • Therapeutic Drug Monitoring, June 2008, Wolters Kluwer Health

    Dr Marie Lordkipanidzé

  107. Comparison of different methods of measurement of aspirin resistance: using the appropriate statistic: reply

    Article • European Heart Journal, December 2007, European Society of Cardiology

    Dr Marie Lordkipanidzé

  108. A comparison of six major platelet function tests to determine the prevalence of aspirin resistance in patients with stable coronary artery disease

    Article • European Heart Journal, March 2007, European Society of Cardiology

    Dr Marie Lordkipanidzé

  109. Aspirin resistance: Truth or dare

    Article • Pharmacology & Therapeutics, December 2006, Elsevier

    Dr Marie Lordkipanidzé