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  1. Fluorescence Lifetime Imaging of Human Sub-RPE Calcification In Vitro Following Chlortetracycline Infusion

    Article • International Journal of Molecular Sciences, March 2023, MDPI AG

    Dr Imre Lengyel

  2. Zinc Supplementation Induced Transcriptional Changes in Primary Human Retinal Pigment Epithelium: A Single-Cell RNA Sequencing Study to Understand Age-Related Macular Degeneration

    Article • Cells, February 2023, MDPI AG

    Dr Imre Lengyel

  3. Zinc supplementation induced transcriptional changes in primary human retinal pigment epithelium: a single cell RNA sequencing study to understand age-related macular degeneration

    Article • September 2022, Cold Spring Harbor Laboratory Press

    Dr Imre Lengyel

  4. A 2,7-dichlorofluorescein derivative to monitor microcalcifications

    Article • Molecular Systems Design & Engineering, January 2022, Royal Society of Chemistry

    Dr Imre Lengyel

  5. A Potential New Role for Zinc in Age-Related Macular Degeneration through Regulation of Endothelial Fenestration

    Article • International Journal of Molecular Sciences, November 2021, MDPI AG

    Dr Imre Lengyel

  6. Characterization of Calcium Phosphate Spherical Particles in the Subretinal Pigment Epithelium–Basal Lamina Space in Aged Human Eyes

    Article • Ophthalmology Science, September 2021, Elsevier

    Dr Imre Lengyel

  7. A Multi-Omics Approach Identifies Key Regulatory Pathways Induced by Long-Term Zinc Supplementation in Human Primary Retinal Pigment Epithelium

    Article • Nutrients, October 2020, MDPI AG

    Dr Imre Lengyel

  8. The Placental Growth Factor Pathway and Its Potential Role in Macular Degenerative Disease

    Article • Current Eye Research, May 2019, Taylor & Francis

    Dr Imre Lengyel

  9. Metabolomics and Age-Related Macular Degeneration

    Article • Metabolites, December 2018, MDPI AG

    Dr Imre Lengyel

  10. The clinical relevance of visualising the peripheral retina

    Article • Progress in Retinal and Eye Research, October 2018, Elsevier

    Dr Imre Lengyel

  11. Precision medicine for age-related macular degeneration: current developments and prospects

    Article • Expert Review of Precision Medicine and Drug Development, July 2018, Taylor & Francis

    Professor Tunde Peto, Dr Imre Lengyel

  12. Genetic differences can cause changes in the level of several proteins in blood samples

    Article • Experimental Eye Research, July 2018, Elsevier

    Dr Imre Lengyel

  13. The effects of zinc supplementation on primary human retinal pigment epithelium

    Article • Journal of Trace Elements in Medicine and Biology, March 2018, Elsevier

    Dr Imre Lengyel

  14. Systemic and ocular fluid compounds as potential biomarkers in age-related macular degeneration

    Article • Survey of Ophthalmology, January 2018, Elsevier

    Dr Imre Lengyel

  15. Localization of the zinc binding tubulin polymerization promoting protein in the mice and human eye

    Article • Journal of Trace Elements in Medicine and Biology, December 2017, Elsevier

    Dr Imre Lengyel

  16. Changes in zinc status and zinc transporters expression in whole blood of patients with Systemic Inflammatory Response Syndrome (SIRS)

    Article • Journal of Trace Elements in Medicine and Biology, November 2017, Elsevier

    Dr Imre Lengyel

  17. Subretinal Pigment Epithelial Deposition of Drusen Components Including Hydroxyapatite in a Primary Cell Culture Model

    Article • Investigative Ophthalmology & Visual Science, February 2017, Association for Research in Vision and Ophthalmology (ARVO)

    Dr Imre Lengyel

  18. Main biomarkers associated with age-related plasma zinc decrease and copper/zinc ratio in healthy elderly from ZincAge study

    Article • Zeitschrift für Ernährungswissenschaft, July 2016, Springer Science + Business Media

    Dr Imre Lengyel

  19. RETINAL IMAGING IN POSTERIOR CORTICAL ATROPHY AND TYPICAL ALZHEIMER’S DISEASE

    Article • Alzheimer s & Dementia, July 2016, Elsevier

    Dr Imre Lengyel

  20. A Population-Based Ultra-Widefield Digital Image Grading Study for Age-Related Macular Degeneration–Like Lesions at the Peripheral Retina

    Article • Ophthalmology, July 2015, Elsevier

    Dr Imre Lengyel

  21. Retinal imaging in early-onset Alzheimer’s disease

    Article • Alzheimer s & Dementia, July 2015, Elsevier

    Dr Imre Lengyel

  22. Retinal nerve fibre layer (RNFL) thinning in genetic ftd

    Article • Alzheimer s & Dementia, July 2015, Elsevier

    Dr Imre Lengyel

  23. Identification of hydroxyapatite spherules provides new insight into subretinal pigment epithelial deposit formation in the aging eye

    Article • Proceedings of the National Academy of Sciences, January 2015, Proceedings of the National Academy of Sciences

    Dr Imre Lengyel

  24. Metals in age-related macular degeneration

    Article • Metallomics, January 2014, Oxford University Press (OUP)

    Dr Imre Lengyel

  25. Zinc-induced self-association of complement C3b and Factor H: Implications for inflammation and age-related macular degeneration

    Article • Molecular Immunology, December 2013, Elsevier

    Dr Imre Lengyel

  26. Zinc-induced Self-association of Complement C3b and Factor H: IMPLICATIONS FOR INFLAMMATION AND AGE-RELATED MACULAR DEGENERATION

    Article • Journal of Biological Chemistry, May 2013, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Imre Lengyel

  27. Zinc Binding to the Tyr402 and His402 Allotypes of Complement Factor H: Possible Implications for Age-Related Macular Degeneration

    Article • Journal of Molecular Biology, May 2011, Elsevier

    Dr Imre Lengyel

  28. The His402 allotype of complement factor H show similar self-association to the Tyr402 allotype but exhibits greater self-association in the presence of zinc

    Article • Molecular Immunology, August 2010, Elsevier

    Dr Imre Lengyel

  29. Agreement between image grading of conventional (45°) and ultra wide-angle (200°) digital images in the macula in the Reykjavik eye study

    Article • Eye, June 2010, Nature

    Dr Imre Lengyel

  30. Bruch's membrane changes in transgenic mice overexpressing the human biglycan and apolipoprotein b-100 genes

    Article • Experimental Eye Research, August 2009, Elsevier

    Dr Imre Lengyel

  31. Uncontrolled Zinc- and Copper-Induced Oligomerisation of the Human Complement Regulator Factor H and Its Possible Implications for Function and Disease

    Article • Journal of Molecular Biology, December 2008, Elsevier

    Dr Imre Lengyel

  32. Uncontrolled zinc- and copper-induced oligomerisation of human complement factor H and its implications for age-related macular degeneration

    Article • Molecular Immunology, October 2008, Elsevier

    Dr Imre Lengyel

  33. Reply to “Comment on: “High concentration of zinc in sub-retinal pigment epithelial deposits” (Lengyel et al.) (Exp. Eye Res. 772–780, 84/4, 2007)”

    Article • Experimental Eye Research, May 2008, Elsevier

    Dr Imre Lengyel

  34. Comment on: “High concentration of zinc in sub-retinal pigment epithelial deposits” (Lengyel et al.) (Exp. Eye Res. 772–780, 84/4, 2007)

    Article • Experimental Eye Research, May 2008, Elsevier

    Dr Imre Lengyel

  35. Cure or cause: opposing roles for zinc in age-related macular degeneration

    Article • Expert Review of Ophthalmology, February 2008, Taylor & Francis

    Dr Imre Lengyel

  36. Bio‐avalibale zinc in the outer segments of short wavelength cones

    Article • Acta Ophthalmologica Scandinavica, September 2007, Wiley

    Dr Imre Lengyel

  37. High concentration of zinc in sub-retinal pigment epithelial deposits

    Article • Experimental Eye Research, April 2007, Elsevier

    Dr Imre Lengyel

  38. Partial and full agonism in endomorphin derivatives: Comparison by null and operational model

    Article • Peptides, June 2006, Elsevier

    Dr Imre Lengyel

  39. Autonomous activity of CaMKII is only transiently increased following the induction of long-term potentiation in the rat hippocampus

    Article • European Journal of Neuroscience, December 2004, Wiley

    Dr Imre Lengyel

  40. Association of Drusen Deposition with Choroidal Intercapillary Pillars in the Aging Human Eye

    Article • Investigative Ophthalmology & Visual Science, September 2004, Association for Research in Vision and Ophthalmology (ARVO)

    Dr Imre Lengyel

  41. Enhancement of NMDA responses by β-amyloid peptides in the hippocampus in vivo

    Article • Neuroreport, July 2004, Wolters Kluwer Health

    Dr Imre Lengyel

  42. Enhanced G-protein activation by a mixture of Abeta(25-35), Abeta(1-40/42) and zinc

    Article • Journal of Neurochemistry, June 2004, Wiley

    Dr Imre Lengyel, Professor Zoltan Molnar

  43. S100B-Mediated Inhibition of the Phosphorylation of GFAP Is Prevented by TRTK-12

    Article • Neurochemical Research, April 2004, Springer Science + Business Media

    Dr Imre Lengyel

  44. Molecular pathomechanisms of Alzheimer's disease

    Article • Journal of Molecular Structure THEOCHEM, December 2003, Elsevier

    Dr Imre Lengyel, Professor Zoltan Molnar

  45. Side Chain Modifications Change the Binding and Agonist Properties of Endomorphin 2

    Article • Biochemical and Biophysical Research Communications, January 2002, Elsevier

    Dr Imre Lengyel

  46. Influence of Degradation on Binding Properties and Biological Activity of Endomorphin 1

    Article • Biochemical and Biophysical Research Communications, June 2001, Elsevier

    Dr Imre Lengyel

  47. Receptor constants for endomorphin-1 and endomorphin-1-ol indicate differences in efficacy and receptor occupancy

    Article • European Journal of Pharmacology, June 2001, Elsevier

    Dr Imre Lengyel

  48. Preparation of specifically tritiated endomorphins

    Article • Journal of Labelled Compounds and Radiopharmaceuticals, April 2001, Wiley

    Dr Imre Lengyel

  49. Auto‐inhibition of Ca2+/calmodulin‐dependent protein kinase II by its ATP‐binding domain

    Article • Journal of Neurochemistry, February 2001, Wiley

    Dr Imre Lengyel

  50. Modulation of the Phosphorylation and Activity of Calcium/Calmodulin‐Dependent Protein Kinase II by Zinc

    Article • Journal of Neurochemistry, August 2000, Wiley

    Dr Imre Lengyel

  51. Simultaneous measurement of tyrosine hydroxylase activity and phosphorylation in bovine adrenal chromaffin cells

    Article • Journal of Neuroscience Methods, March 1999, Elsevier

    Dr Imre Lengyel

  52. α and β subunits of CaM-kinase II are localized in different neurons in chick ciliary ganglion

    Article • Neuroreport, August 1998, Wolters Kluwer Health

    Dr Imre Lengyel

  53. Calcium/Calmodulin‐Stimulated Protein Kinase II Is Present in Primary Cultures of Cerebral Endothelial Cells

    Article • Journal of Neurochemistry, May 1993, Wiley

    Dr Imre Lengyel, Dr Maria A Deli

  54. Pathological Phosphorylation Causes Neuronal Death: Effect of Okadaic Acid in Primary Culture of Cerebellar Granule Cells

    Article • Journal of Neurochemistry, October 1992, Wiley

    Dr Imre Lengyel

  55. Zinc can modulate the phosphorylation and activity of CAMK in freshly isolated rat brain capillaries

    Article • Neurochemistry International, January 1992, Elsevier

    Dr Imre Lengyel