All Stories

  1. Treatment and management of thyroid storm: analysis of the nationwide surveys

    Article • Clinical Endocrinology, October 2015, Wiley

    Dr Osamu Isozaki

  2. DNA Mismatch Repair Protein (MSH6) Correlated With the Responses of Atypical Pituitary Adenomas and Pituitary Carcinomas to Temozolomide: The National Cooperative Study by the Japan Society for Hypothalamic and Pituitary Tumors

    Article • The Journal of Clinical Endocrinology & Metabolism, March 2013, Endocrine Society

    Dr Osamu Isozaki

  3. Diagnostic Criteria, Clinical Features, and Incidence of Thyroid Storm Based on Nationwide Surveys

    Article • Thyroid, July 2012, Mary Ann Liebert Inc

    Dr Osamu Isozaki

  4. Diagnostic criteria and clinico-epidemiological features of thyroid storm based on a nationwide survey

    Article • Thyroid, April 2012, Mary Ann Liebert Inc

    Dr Osamu Isozaki

  5. 1. Subclinical Thyroid Dysfunctions.

    Article • Nihon Naika Gakkai Zasshi, January 2010, Japanese Society of Internal Medicine

    Dr Osamu Isozaki

  6. Clinical Characteristics of Frequently Recurring Painless Thyroiditis: Contributions of Higher Thyroid Hormone Levels, Younger Onset, Male Gender, Presence of Thyroid Autoantibody and Absence of Goiter to Repeated Recurrence

    Article • Endocrine Journal, January 2009, Japan Endocrine Society

    Dr Osamu Isozaki

  7. Serum Concentrations of BNP and ANP in Patients with Thyrotoxicosis

    Article • Endocrine Journal, January 2009, Japan Endocrine Society

    Dr Osamu Isozaki

  8. Anti-Glutamic Acid Decarboxylase Antibody in Graves' Disease Is A Possible Indicator for The Unlikelihood of Going into Remission with Antithyroid Agents

    Article • Endocrine Journal, January 2009, Japan Endocrine Society

    Dr Osamu Isozaki

  9. Insulinoma with Six Islet Cell Tumors Associated with Severe Hypoglycemia

    Article • Internal Medicine, January 2009, Japanese Society of Internal Medicine

    Dr Osamu Isozaki

  10. Huge Thyroid Uptake of 18 F-FDG in a Patient with Hashimoto's Thyroiditis Referred for a Malignant Thyroid Lesion

    Article • Thyroid, May 2008, Mary Ann Liebert Inc

    Dr Osamu Isozaki

  11. Expression of Type 5 Somatostatin Receptor in TSH-secreting Pituitary Adenomas: A Possible Marker for Predicting Long-term Response to Octreotide Therapy

    Article • Endocrine Journal, January 2007, Japan Endocrine Society

    Dr Osamu Isozaki

  12. P-86 A CASE OF ACROMEGALY ACCOMPANIED BY McCUNE-ALBRIGHT SYNDROME AND PROGRESSIVE SYSTEMIC SCLEROSIS

    Article • Growth Hormone & IGF Research, November 2006, Elsevier

    Dr Osamu Isozaki

  13. Application of cell-sheet engineering for reconstitution of functional thyroid tissue from isolated thyroid cells

    Article • Inflammation and Regeneration, January 2006, Japanese Society of Inflammation and Regeneration

    Dr Osamu Isozaki

  14. Leptin Regulation of the Thyroids: Negative Regulation on Thyroid Hormone Levels in Euthyroid Subjects and Inhibitory Effects on Iodide Uptake and Na+/I– Symporter mRNA Expression in Rat FRTL-5 Cells

    Article • Endocrine Journal, January 2004, Japan Endocrine Society

    Dr Osamu Isozaki

  15. Increased Expression of Phosphorylated p70S6 Kinase and Akt in Papillary Thyroid Cancer Tissues.

    Article • Endocrine Journal, January 2003, Japan Endocrine Society

    Dr Osamu Isozaki

  16. A Man with Interstitial Pneumonia Due to Propylthiouracil

    Article • Internal Medicine, January 2003, Japanese Society of Internal Medicine

    Dr Osamu Isozaki

  17. Serum Leptin Levels and Bioelectrical Impedance Assessment of Body Composition in Patients with Graves' Disease and Hypothyroidism.

    Article • Endocrine Journal, January 1999, Japan Endocrine Society

    Dr Osamu Isozaki

  18. Interaction between Leptin and Growth Hormone (GH)/IGF-I Axis

    Article • Endocrine Journal, January 1999, Japan Endocrine Society

    Dr Osamu Isozaki

  19. Effect of Cytokines on Production of Insulin-like Growth Factor Binding Proteins (IGFBPs) from Human Fibroblasts in Culture

    Article • Endocrine Journal, January 1999, Japan Endocrine Society

    Dr Osamu Isozaki

  20. High Prevalence of T354P Sodium/Iodide Symporter Gene Mutation in Japanese Patients with Iodide Transport Defect Who Have Heterogeneous Clinical Pictures1

    Article • The Journal of Clinical Endocrinology & Metabolism, November 1998, Endocrine Society

    Dr Osamu Isozaki

  21. Effect of Growth Hormone (GH) on Serum Concentrations of Leptin: Study in Patients with Acromegaly and GH Deficiency1

    Article • The Journal of Clinical Endocrinology & Metabolism, October 1998, Endocrine Society

    Dr Osamu Isozaki

  22. Effects of Growth Hormone on Leptin Gene Expression in Rats

    Article • Endocrine Journal, January 1998, Japan Endocrine Society

    Dr Osamu Isozaki

  23. Protein Kinase C (PKC)-Mediated Growth Hormone (GH) Actions

    Article • Endocrine Journal, January 1998, Japan Endocrine Society

    Dr Osamu Isozaki

  24. Oncostatin M: A New Potent Inhibitor of Iodine Metabolism Inhibits Thyroid Peroxidase Gene Expression But Not DNA Synthesis in Porcine Thyroid Cells in Culture

    Article • Thyroid, February 1997, Mary Ann Liebert Inc

    Dr Osamu Isozaki

  25. Expression of Insulin-Like Growth Factor Binding Proteins (IGFBPs) in Human Thyroid Papillary Cancer Tissues.

    Article • Endocrine Journal, January 1996, Japan Endocrine Society

    Dr Osamu Isozaki

  26. Degradation of Cell Surface Heparan Sulfates Decreases the High Affinity Binding of Basic FGF to Endothelial Cells, but Not to FRTL-5 Rat Thyroid Cells

    Article • Thyroid, December 1995, Mary Ann Liebert Inc

    Dr Osamu Isozaki

  27. Effects of transforming growth factor   (TGF- ) on DNA synthesis and thyrotropin-induced iodine metabolism in cultured porcine thyroid cells

    Article • February 1995

    Dr Osamu Isozaki

  28. Big Insulin-like Growth Factor II-producing Hepatocellular Carcinoma Associated with Hypoglycemia.

    Article • Internal Medicine, January 1995, Japanese Society of Internal Medicine

    Dr Osamu Isozaki

  29. Interaction of endothelin-1 with porcine thyroid cells in culture: a possible autocrine factor regulating iodine metabolism

    Article • September 1994, Bioscientifica

    Dr Osamu Isozaki

  30. Mechanism of inhibitory actions of minocycline and doxycycline on ascitic fluid production induced by mouse fibrosarcoma cells

    Article • Life Sciences, January 1994, Elsevier

    Dr Osamu Isozaki

  31. Iodine Regulation of Endothelin-1 Gene Expression in Cultured Porcine Thyroid Cells: Possible Involvement in Autoregulation of the Thyroid

    Article • Thyroid, January 1993, Mary Ann Liebert Inc

    Dr Osamu Isozaki

  32. Opposite regulation of deoxyribonucleic acid synthesis and iodide uptake in rat thyroid cells by basic fibroblast growth factor: correlation with opposite regulation of c-fos and thyrotropin receptor gene expression

    Article • Endocrinology, December 1992, Endocrine Society

    Dr Osamu Isozaki

  33. Opposite regulation of deoxyribonucleic acid synthesis and iodide uptake in rat thyroid cells by basic fibroblast growth factor: correlation with opposite regulation of c-fos and thyrotropin receptor gene expression.

    Article • Endocrinology, December 1992, Endocrine Society

    Dr Osamu Isozaki

  34. Endothelin-1 stimulates c-fos mRNA expression and acts as a modulator on cell proliferation of rat FRTL5 thyroid cells

    Article • Biochemical and Biophysical Research Communications, April 1992, Elsevier

    Dr Osamu Isozaki

  35. Thyroid ultrasonography related to clinical and laboratory findings in patients with silent thyroiditis

    Article • Journal of Endocrinological Investigation, April 1992, Springer Science + Business Media

    Dr Osamu Isozaki

  36. Autocrine role of insulin-like growth factor (IGF)-I in a human thyroid cancer cell line

    Article • European Journal of Cancer, January 1992, Elsevier

    Dr Osamu Isozaki

  37. Effects of Retinoids on Iodine Metabolism, Thyroid Peroxidase Gene Expression, and Deoxyribonucleic Acid Synthesis in Porcine Thyroid Cells in Culture*

    Article • Endocrinology, December 1991, Endocrine Society

    Dr Osamu Isozaki

  38. An Immunoneutralizing Anti-Basic-FGF Antibody Potentiates the Effect of Basic FGF on the Growth of FRTL-5 Thyroid Cells

    Article • Annals of the New York Academy of Sciences, December 1991, Wiley

    Dr Osamu Isozaki

  39. Effects of Glucocorticoids and Calcitonin on Parathyroid Hormone-related Protein (PTHrP) Gene Expression and PTHrP Release in Human Cancer Cells Causing Humoral Hypercalcemia1

    Article • Japanese Journal of Cancer Research, September 1991, Wiley

    Dr Osamu Isozaki

  40. Methimazole Regulation of Thyroglobulin Biosynthesis and Gene Transcription in Rat FRTL-5 Thyroid Cells*

    Article • Endocrinology, June 1991, Endocrine Society

    Dr Osamu Isozaki

  41. Phorbol ester, not growth hormone releasing factor, consistently stimulates growth hormone release from somatotroph adenomas in culture

    Article • Clinical Endocrinology, May 1991, Wiley

    Dr Osamu Isozaki

  42. Identification and Characterization of Basic Fibroblast Growth Factor in Porcine Thyroids*

    Article • Endocrinology, January 1991, Endocrine Society

    Dr Osamu Isozaki

  43. Effect of Lithium on Deoxyribonucleic Acid Synthesis and Iodide Uptake in Porcine Thyroid Cells in Culture*

    Article • Endocrinology, January 1990, Endocrine Society

    Dr Osamu Isozaki

  44. Thyroid Peroxidase: Rat cDNA Sequence, Chromosomal Localization in Mouse, and Regulation of Gene Expression by Comparison to Thyroglobulin in Rat FRTL-5 Cells

    Article • Molecular Endocrinology, November 1989, Endocrine Society

    Dr Osamu Isozaki

  45. Receptors of the Thyroid: The Thyrotropin Receptor is Only the First Violinist of a Symphony Orchestra

    Article • January 1989, Springer Science + Business Media

    Dr Osamu Isozaki

  46. Antibodies to the Thyrotropin (TSH) Receptor and Autoimmune Thyroid Disease

    Article • January 1989, Springer Science + Business Media

    Dr Osamu Isozaki

  47. The inhibitory effect of iodide on growth of rat thyroid (FRTL-5) cells

    Article • September 1988

    Dr Osamu Isozaki

  48. Control of c-fos and c-myc Proto-Oncogene Induction in Rat Thyroid Cells in Culture

    Article • Molecular Endocrinology, November 1987, Endocrine Society

    Dr Osamu Isozaki

  49. TSH and biogenic amine signals in the regulation of thyroid function: Independent regulation by protein kinase C and G proteins

    Article • August 1987

    Dr Osamu Isozaki

  50. Interaction of Insulin-Like Growth Factor I with Porcine Thyroid Cells Cultured in Monolayer*

    Article • Endocrinology, August 1987, Endocrine Society

    Dr Osamu Isozaki

  51. Nature of Thyroid Autoantigens: The TSH Receptor

    Article • January 1987, Springer Science + Business Media

    Dr Osamu Isozaki

  52. An Unusual Type of Familial Dysalbuminemic Hyperthyroxinemia in a Japanese Family

    Article • January 1986, Springer Science + Business Media

    Dr Osamu Isozaki

  53. Thyroid-Stimulating Antibody Bioassay Using Porcine Thyroid Cells Cultured in Follicles*

    Article • The Journal of Clinical Endocrinology & Metabolism, December 1985, Endocrine Society

    Dr Osamu Isozaki

  54. Triiodothyronine binding immunoglobulin in a euthyroid man without apparent thyroid disease; its properties and effects on triiodothyronine metabolism

    Article • April 1985

    Dr Osamu Isozaki

  55. Processing of Human Growth Hormone by Rat Hepatocytes in Monolayer Culture*

    Article • Endocrinology, May 1984, Endocrine Society

    Dr Osamu Isozaki

  56. A patient of short stature with idiopathic hypoparathyroidism round face and metacarpal signs.

    Article • Endocrinologia Japonica, January 1984, Japan Endocrine Society

    Dr Osamu Isozaki

  57. A case of pachygyria associated with total hemiatrophy and partial epilepsy.

    Article • Nihon Naika Gakkai Zasshi, January 1984, Japanese Society of Internal Medicine

    Dr Osamu Isozaki

  58. Analysis of hepatic growth hormone binding sites of pregnant rabbit crosslinked to 125 I-labelled human growth hormone

    Article • FEBS Letters, October 1982, Wiley

    Dr Osamu Isozaki