All Stories

  1. The poro-elastic behaviour of the intervertebral disc: A new perspective on diurnal fluid flow

    Article • Journal of Biomechanics, April 2016, Elsevier

    Theodoor Smit

  2. Translational challenges for the development of a novel nucleus pulposus substitute: Experimental results from biomechanical and in vivo studies

    Article • Journal of Biomaterials Applications, October 2015, SAGE Publications

    Theodoor Smit

  3. Mechanics and biology in intervertebral disc degeneration: a vicious circle

    Article • Osteoarthritis and Cartilage, July 2015, Elsevier

    Theodoor Smit

  4. The effect of neighboring segments on the measurement of segmental stiffness in the intact lumbar spine

    Article • The Spine Journal, June 2015, Elsevier

    Theodoor Smit

  5. A Biodegradable Glue for Annulus Closure

    Article • Spine, May 2015, Wolters Kluwer Health

    Theodoor Smit

  6. Adverse effects of stromal vascular fraction during regenerative treatment of the intervertebral disc: observations in a goat model

    Article • European Spine Journal, February 2015, Springer Science + Business Media

    Theodoor Smit

  7. Spinal fusion using adipose stem cells seeded on a radiolucent cage filler: a feasibility study of a single surgical procedure in goats

    Article • European Spine Journal, November 2014, Springer Science + Business Media

    Theodoor Smit

  8. Long-Term Creep Behavior of the Intervertebral Disk: Comparison between Bioreactor Data and Numerical Results

    Article • Frontiers in Bioengineering and Biotechnology, November 2014, Frontiers

    Theodoor Smit

  9. Functional characteristics of vaginal fibroblastic cells from premenopausal women with pelvic organ prolapse

    Article • Molecular Human Reproduction, September 2014, Oxford University Press (OUP)

    Theodoor Smit, Dr Alejandra M. Ruiz-Zapata

  10. MRI T2* mapping correlates with biochemistry and histology in intervertebral disc degeneration in a large animal model

    Article • European Spine Journal, August 2014, Springer Science + Business Media

    Theodoor Smit

  11. Intradiscal pressure depends on recent loading and correlates with disc height and compressive stiffness

    Article • European Spine Journal, July 2014, Springer Science + Business Media

    Theodoor Smit

  12. Relation between radiological assessment and biomechanical stability of lumbar interbody fusion in a large animal model

    Article • European Spine Journal, September 2013, Springer Science + Business Media

    Theodoor Smit

  13. One-Step Surgical Procedure for the Treatment of Osteochondral Defects with Adipose-Derived Stem Cells in a Caprine Knee Defect: A Pilot Study

    Article • BioResearch Open Access, August 2013, Mary Ann Liebert Inc

    Theodoor Smit

  14. Dynamic and Static Overloading Induce Early Degenerative Processes in Caprine Lumbar Intervertebral Discs

    Article • PLoS ONE, April 2013, PLOS

    Theodoor Smit

  15. Fibroblasts from women with pelvic organ prolapse show differential mechanoresponses depending on surface substrates

    Article • International Urogynecology Journal, April 2013, Springer Science + Business Media

    Theodoor Smit, Dr Alejandra M. Ruiz-Zapata

  16. Cell mediated contraction in 3D cell-matrix constructs leads to spatially regulated osteogenic differentiation

    Article • Integrative Biology, January 2013, Oxford University Press (OUP)

    Theodoor Smit

  17. Biomechanical and rheological characterization of mild intervertebral disc degeneration in a large animal model

    Article • Journal of Orthopaedic Research®, December 2012, Wiley

    Theodoor Smit

  18. Changes in Biomechanical, Histological and Quantitative MRI Parameters in Lumbar Caprine Intervertebral Discs Subjected to Chondroïtinase-Induced Degeneration

    Article • Global Spine Journal, September 2012, Thieme Publishing Group

    Theodoor Smit

  19. Biomechanical evaluation of a novel nucleus pulposus prosthesis in canine cadaveric spines

    Article • The Veterinary Journal, May 2012, Elsevier

    Theodoor Smit

  20. Simulated-Physiological Loading Conditions Preserve Biological and Mechanical Properties of Caprine Lumbar Intervertebral Discs in Ex Vivo Culture

    Article • PLoS ONE, March 2012, PLOS

    Theodoor Smit

  21. In vivo models of regenerative medicine in the spine

    Article • January 2012, Elsevier

    Theodoor Smit

  22. The feasibility of modal testing for measurement of the dynamic characteristics of goat vertebral motion segments

    Article • Journal of Biomechanics, May 2011, Elsevier

    Theodoor Smit

  23. The Use of Poly(L -lactide-co -caprolactone) as a Scaffold for Adipose Stem Cells in Bone Tissue Engineering: Application in a Spinal Fusion Model

    Article • Macromolecular Bioscience, March 2011, Wiley

    Theodoor Smit

  24. Quantifying intervertebral disc mechanics: a new definition of the neutral zone

    Article • BMC Musculoskeletal Disorders, February 2011, Springer Science + Business Media

    Theodoor Smit

  25. Posterior lumbar interbody fusion using non resorbable poly-ether-ether-ketone versus resorbable poly-l-lactide-co-d,l-lactide fusion devices. Clinical outcome at a minimum of 2-year follow-up

    Article • European Spine Journal, September 2010, Springer Science + Business Media

    Theodoor Smit

  26. The effect of ethylene oxide, glow discharge and electron beam on the surface characteristics of poly(l-lactide-co-caprolactone) and the corresponding cellular response of adipose stem cells

    Article • Acta Biomaterialia, June 2010, Elsevier

    Theodoor Smit

  27. Biomechanical and in vivo evaluation of experimental closure devices of the annulus fibrosus designed for a goat nucleus replacement model

    Article • European Spine Journal, April 2010, Springer Science + Business Media

    Theodoor Smit

  28. Is BMU-Coupling a Strain-Regulated Phenomenon? A Finite Element Analysis

    Article • Journal of Bone and Mineral Research, February 2010, Wiley

    Theodoor Smit

  29. Inorganic Phosphate Stimulates DMP1 Expression in Human Periodontal Ligament Fibroblasts Embedded in Three-Dimensional Collagen Gels

    Article • Cells Tissues Organs, January 2010, Karger Publishers

    Theodoor Smit

  30. Three-Dimensional Loading Model for Periodontal Ligament Regeneration In Vitro

    Article • Tissue Engineering Part C Methods, December 2009, Mary Ann Liebert Inc

    Theodoor Smit

  31. Osteocyte morphology in human tibiae of different bone pathologies with different bone mineral density — Is there a role for mechanosensing?

    Article • Bone, August 2009, Elsevier

    Theodoor Smit

  32. Biodegradable Polymers in Bone Tissue Engineering

    Article • Materials, July 2009, MDPI AG

    Theodoor Smit

  33. PLDLA mesh and 60/40 biphasic calcium phosphate in iliac crest regeneration in the goat

    Article • Journal of Biomedical Materials Research Part B Applied Biomaterials, April 2009, Wiley

    Theodoor Smit

  34. Collagen type V modulates fibroblast behavior dependent on substrate stiffness

    Article • Biochemical and Biophysical Research Communications, March 2009, Elsevier

    Theodoor Smit

  35. Posterior Lumbar Interbody Fusion Using Nonresorbable Poly-Ether-Ether-Ketone Versus Resorbable Poly-l-Lactide-Co-d,l-Lactide Fusion Devices

    Article • Spine, February 2009, Wolters Kluwer Health

    Theodoor Smit

  36. Repair, regenerative and supportive therapies of the annulus fibrosus: achievements and challenges

    Article • European Spine Journal, December 2008, Springer Science + Business Media

    Theodoor Smit

  37. Paxillin localisation in osteocytes—Is it determined by the direction of loading?

    Article • Biochemical and Biophysical Research Communications, December 2008, Elsevier

    Theodoor Smit

  38. Osteocyte morphology in fibula and calvaria — Is there a role for mechanosensing?

    Article • Bone, September 2008, Elsevier

    Theodoor Smit

  39. Erratum to “Round versus flat: Bone cell morphology, elasticity, and mechanosensing” [J. Biomech. 41 (2008) 1590–1598]

    Article • Journal of Biomechanics, August 2008, Elsevier

    Theodoor Smit

  40. Corrigendum to “Contribution of vertebral bodies, endplates, and intervertebral discs to the compression creep of spinal motion segments”

    Article • Journal of Biomechanics, July 2008, Elsevier

    Theodoor Smit

  41. SUBSTRATE RIGIDITY AND EXTRACELLULAR MATRIX COMPOSITION INTERACT TO DETERMINE CELL BEHAVIOR

    Article • Journal of Biomechanics, July 2008, Elsevier

    Theodoor Smit

  42. Scaffold Stiffness Influences Cell Behavior: Opportunities for Skeletal Tissue Engineering

    Article • The Open Orthopaedics Journal, June 2008, Bentham Science Publishers

    Theodoor Smit

  43. Tissue identification with micro-magnetic resonance imaging in a caprine spinal fusion model

    Article • European Spine Journal, May 2008, Springer Science + Business Media

    Theodoor Smit

  44. Bone Remodeling

    Article • May 2008, Taylor & Francis

    Theodoor Smit

  45. Adjacent Segment Degeneration

    Article • Spine, May 2008, Wolters Kluwer Health

    Theodoor Smit

  46. Reproducible Long-term Disc Degeneration in a Large Animal Model

    Article • Spine, April 2008, Wolters Kluwer Health

    Theodoor Smit

  47. Effect of long-term preservation on the mechanical properties of cortical bone in goats

    Article • Acta Orthopaedica, January 2008, Taylor & Francis

    Theodoor Smit

  48. Time-Dependent Mechanical Strength of 70/30 Poly(l,dl-lactide)

    Article • Spine, January 2008, Wolters Kluwer Health

    Theodoor Smit

  49. Round versus flat: Bone cell morphology, elasticity, and mechanosensing

    Article • Journal of Biomechanics, January 2008, Elsevier

    Theodoor Smit

  50. Contribution of verftebral bodies, endplates, and intervertebral discs to the compression creep of spinal motion segments

    Article • Journal of Biomechanics, January 2008, Elsevier

    Theodoor Smit

  51. Effectiveness of preoperative planning in the restoration of balance and view in ankylosing spondylitis

    Article • Neurosurgical FOCUS, January 2008, Journal of Neurosurgery Publishing Group (JNSPG)

    Theodoor Smit

  52. Paul Wuisman

    Article • Spine, December 2007, Wolters Kluwer Health

    Theodoor Smit

  53. Effects of Dorsal Versus Ventral Shear Loads on the Rotational Stability of the Thoracic Spine

    Article • Spine, November 2007, Wolters Kluwer Health

    Theodoor Smit

  54. Microgravity and bone cell mechanosensitivity: FLOW experiment during the DELTA mission

    Article • Microgravity Science and Technology, September 2007, Springer Science + Business Media

    Theodoor Smit

  55. Experimental Intervertebral Disc Degeneration Induced by Chondroitinase ABC in the Goat

    Article • Spine, August 2007, Wolters Kluwer Health

    Theodoor Smit

  56. Alkaline phosphatase-induced mineral deposition to anchor collagen fibrils to a solid surface

    Article • Biomaterials, August 2007, Elsevier

    Theodoor Smit

  57. ASKyphoplan: a program for deformity planning in ankylosing spondylitis

    Article • European Spine Journal, April 2007, Springer Science + Business Media

    Theodoor Smit

  58. Sterilization and Strength of 70/30 Polylactide Cages

    Article • Spine, April 2007, Wolters Kluwer Health

    Theodoor Smit

  59. A biomechanical analysis of the self-retaining pedicle hook device in posterior spinal fixation

    Article • European Spine Journal, January 2007, Springer Science + Business Media

    Theodoor Smit

  60. Extracellular NO signalling from a mechanically stimulated osteocyte

    Article • Journal of Biomechanics, January 2007, Elsevier

    Theodoor Smit

  61. Intervertebral disc recovery after dynamic or static loading in vitro: Is there a role for the endplate?

    Article • Journal of Biomechanics, January 2007, Elsevier

    Theodoor Smit

  62. Application of polylactides in spinal cages: Studies in a goat model

    Article • Journal of Materials Science Materials in Medicine, December 2006, Springer Science + Business Media

    Theodoor Smit

  63. Collagen type V enhances matrix contraction by human periodontal ligament fibroblasts seeded in three-dimensional collagen gels

    Article • Matrix Biology, October 2006, Elsevier

    Theodoor Smit

  64. Biomechanical comparison of hard and soft hip protectors, and the influence of soft tissue

    Article • Bone, August 2006, Elsevier

    Theodoor Smit

  65. Bio Imaging of Intracellular NO Production in Single Bone Cells After Mechanical Stimulation

    Article • Journal of Bone and Mineral Research, July 2006, Wiley

    Theodoor Smit

  66. Does Bioresorbable Cage Material Influence Segment Stability in Spinal Interbody Fusion?

    Article • Clinical Orthopaedics and Related Research, July 2006, Wolters Kluwer Health

    Theodoor Smit

  67. Radiographic, Histologic, and Chemical Evaluation of Bioresorbable 70/30 Poly-L-lactide-CO-D, L-lactide Interbody Fusion Cages in a Goat Model

    Article • Spine, June 2006, Wolters Kluwer Health

    Theodoor Smit

  68. Heparine perfusiondoes not improve mechanical recovery of intervertebral discs in vitro

    Article • Journal of Biomechanics, January 2006, Elsevier

    Theodoor Smit

  69. Primary spinal segment stability with a stand-alone cage: In vitro evaluation of a successful goat model

    Article • Acta Orthopaedica, January 2006, Taylor & Francis

    Theodoor Smit

  70. Lumbar body fusion with a bioresorbable cage in a goat model is delayed by the use of a carboxymethylcellulose-stabilized collagenous rhOP-1 device

    Article • Journal of Orthopaedic Research®, January 2006, Wiley

    Theodoor Smit

  71. Microheology and force traction of mechanosensitive bone cells

    Article • Journal of Biomechanics, January 2006, Elsevier

    Theodoor Smit

  72. Noise-enhanced response of bone cells to fluid shear stress

    Article • Journal of Biomechanics, January 2006, Elsevier

    Theodoor Smit

  73. Bioresorbable polymers: heading for a new generation of spinal cages

    Article • European Spine Journal, November 2005, Springer Science + Business Media

    Theodoor Smit

  74. The effect of the antimicrobial peptide, Dhvar-5, on gentamicin release from a polymethyl methacrylate bone cement

    Article • Biomaterials, October 2005, Elsevier

    Theodoor Smit

  75. The role of osteocytes in bone mechanotransduction

    Article • Current Opinion in Orthopedics, October 2005, Wolters Kluwer Health

    Theodoor Smit

  76. Transpedicular wedge resection osteotomy for the treatment of a kyphotic Andersson lesion-complicating ankylosing spondylitis

    Article • European Spine Journal, September 2005, Springer Science + Business Media

    Theodoor Smit

  77. Letters

    Article • Spine, September 2005, Wolters Kluwer Health

    Theodoor Smit

  78. Flow-Related Mechanics of the Intervertebral Disc: The Validity of an In Vitro Model

    Article • Spine, September 2005, Wolters Kluwer Health

    Theodoor Smit

  79. A Bioresorbable Molding Mesh for Impaction Grafting Revision Hip Surgery

    Article • Clinical Orthopaedics and Related Research, March 2005, Springer Science + Business Media

    Theodoor Smit

  80. Four-Year Follow-Up of Poly-L-Lactic Acid Cages for Lumbar Interbody Fusion in Goats

    Article • Journal of Long-Term Effects of Medical Implants, January 2005, Begell House

    Theodoor Smit

  81. Dynamic shear stress in parallel-plate flow chambers

    Article • Journal of Biomechanics, January 2005, Elsevier

    Theodoor Smit

  82. Initial Stress-Kick Is Required for Fluid Shear Stress-Induced Rate Dependent Activation of Bone Cells

    Article • Annals of Biomedical Engineering, January 2005, Springer Science + Business Media

    Theodoor Smit

  83. The role of dorsal shear forces in the pathogenesis of adolescent idiopathic scoliosis – A hypothesis

    Article • Medical Hypotheses, January 2005, Elsevier

    Theodoor Smit

  84. The use of high-resolution magnetic resonance imaging for monitoring interbody fusion and bioabsorbable cages: an ex vivo pilot study

    Article • Neurosurgical FOCUS, March 2004, Journal of Neurosurgery Publishing Group (JNSPG)

    Theodoor Smit

  85. Nitric oxide production by bone cells is fluid shear stress rate dependent

    Article • Biochemical and Biophysical Research Communications, March 2004, Elsevier

    Theodoor Smit

  86. Three-Year Follow-up of Bioabsorbable PLLA Cages for Lumbar Interbody Fusion: In Vitro and In Vivo Degradation

    Article • January 2004, Springer Science + Business Media

    Theodoor Smit

  87. Tricalcium-Phosphate/Hydroxyapatite Bone Graft Extender for Use in Impaction Grafting Revision Surgery – an In Vitro Study in Human Femora

    Article • Key Engineering Materials, January 2004, Trans Tech Publications

    Theodoor Smit

  88. Strain-derived canalicular fluid flow regulates osteoclast activity in a remodelling osteon—a proposal

    Article • Journal of Biomechanics, October 2003, Elsevier

    Theodoor Smit

  89. Changes in Bone Architecture During Spinal Fusion: Three Years Follow-up and the Role of Cage Stiffness

    Article • Spine, August 2003, Wolters Kluwer Health

    Theodoor Smit

  90. Bioabsorbable Poly-L-Lactic Acid Cages for Lumbar Interbody Fusion

    Article • Spine, December 2002, Wolters Kluwer Health

    Theodoor Smit

  91. Resorbable cages for spinal fusion: an experimental goat model

    Article • Journal of Neurosurgery Spine, November 2002, Journal of Neurosurgery Publishing Group (JNSPG)

    Theodoor Smit

  92. A Case for Strain-Induced Fluid Flow as a Regulator of BMU-Coupling and Osteonal Alignment

    Article • Journal of Bone and Mineral Research, November 2002, Wiley

    Theodoor Smit

  93. Bone histomorphometric evaluation of a clinically fused titanium tumour cage in a child

    Article • European Spine Journal, October 2002, Springer Science + Business Media

    Theodoor Smit

  94. The Effect of Cage Stiffness on the Rate of Lumbar Interbody Fusion

    Article • Spine, April 2002, Wolters Kluwer Health

    Theodoor Smit

  95. The use of a quadruped as an in vivo model for the study of the spine – biomechanical considerations

    Article • European Spine Journal, April 2002, Springer Science + Business Media

    Theodoor Smit

  96. In vitro andin vivo degradation of bioabsorbable PLLA spinal fusion cages

    Article • Journal of Biomedical Materials Research, January 2002, Wiley

    Theodoor Smit

  97. Polyurethane Real-Size Models Used in Planning Complex Spinal Surgery

    Article • Spine, September 2001, Wolters Kluwer Health

    Theodoor Smit

  98. Mechanical Loading 1

    Article • Journal of Biomechanics, September 2001, Elsevier

    Theodoor Smit

  99. Disorders in trunk rotation during walking in patients with low back pain: a dynamical systems approach

    Article • Clinical Biomechanics, March 2001, Elsevier

    Theodoor Smit

  100. Deformity planning for sagittal plane corrective osteotomies of the spine in ankylosing spondylitis

    Article • European Spine Journal, December 2000, Springer Science + Business Media

    Theodoor Smit

  101. Imaging artifacts in mechanically driven ultrasound catheters

    Article • The International Journal of Cardiovascular Imaging, June 1989, Springer Science + Business Media

    Theodoor Smit

  102. Imaging artifacts in mechanically driven ultrasound catheters

    Article • January 1989, Springer Science + Business Media

    Theodoor Smit