All Stories

  1. A phase I, randomized, controlled, dose-ranging study of investigational acellular pertussis (aP) and reduced tetanus-diphtheria-acellular pertussis (TdaP) booster vaccines in adults

    Article • Human Vaccines & Immunotherapeutics, November 2017, Taylor & Francis

    Professor Geert Leroux-Roels, Dr Sylvie Bertholet

  2. Induction of Broad-Based Immunity and Protective Efficacy by Self-amplifying mRNA Vaccines Encoding Influenza Virus Hemagglutinin

    Article • Journal of Virology, October 2015, ASM Journals

    Dr Sylvie Bertholet

  3. MF59- and Al(OH)3-Adjuvanted Staphylococcus aureus (4C-Staph) Vaccines Induce Sustained Protective Humoral and Cellular Immune Responses, with a Critical Role for Effector CD4 T Cells at Low Antibody Titers

    Article • Frontiers in Immunology, September 2015, Frontiers

    Dr Sylvie Bertholet

  4. Expression and Characterization of Recombinant, Tetrameric and Enzymatically Active Influenza Neuraminidase for the Setup of an Enzyme-Linked Lectin-Based Assay

    Article • PLoS ONE, August 2015, PLOS

    Dr Sylvie Bertholet

  5. An Innovative Pseudotypes-Based Enzyme-Linked Lectin Assay for the Measurement of Functional Anti-Neuraminidase Antibodies

    Article • PLoS ONE, August 2015, PLOS

    Dr Sylvie Bertholet

  6. B Cells and Functional Antibody Responses to Combat Influenza

    Article • Frontiers in Immunology, June 2015, Frontiers

    Dr Sylvie Bertholet

  7. Innate Response Activator (IRA) B Cells Reside in Human Tonsils and Internalize Bacteria In Vitro

    Article • PLoS ONE, June 2015, PLOS

    Dr Sylvie Bertholet

  8. Gaps in knowledge and prospects for research of adjuvanted vaccines

    Article • Vaccine, June 2015, Elsevier

    Dr Sylvie Bertholet

  9. Four-Component Staphylococcus aureus Vaccine 4C-Staph Enhances Fcγ Receptor Expression in Neutrophils and Monocytes and Mitigates S. aureus Infection in Neutropenic Mice

    Article • Infection and Immunity, May 2015, ASM Journals

    Dr Sylvie Bertholet

  10. Phagocyte subsets and lymphocyte clonal deletion behind ineffective immune response to Staphylococcus aureus

    Article • FEMS Microbiology Reviews, May 2015, Oxford University Press (OUP)

    Dr Sylvie Bertholet

  11. Vaccine composition formulated with a novel TLR7-dependent adjuvant induces high and broad protection against Staphylococcus aureus

    Article • Proceedings of the National Academy of Sciences, March 2015, Proceedings of the National Academy of Sciences

    Dr Sylvie Bertholet, Dr Ravi PN Mishra

  12. Evaluating the efficiency of isotope transmission for improved panel design and a comparison of the detection sensitivities of mass cytometer instruments

    Article • Cytometry Part A, February 2015, Wiley

    Dr Sylvie Bertholet

  13. Sublingual immunization with a subunit influenza vaccine elicits comparable systemic immune response as intramuscular immunization, but also induces local IgA and TH17 responses

    Article • Vaccine, April 2014, Elsevier

    Dr Sylvie Bertholet

  14. Rapidly produced SAM® vaccine against H7N9 influenza is immunogenic in mice

    Article • Emerging Microbes & Infections, August 2013, Nature

    Dr Sylvie Bertholet

  15. The adjuvant effect of MF59 is due to the oil-in-water emulsion formulation, none of the individual components induce a comparable adjuvant effect

    Article • Vaccine, July 2013, Elsevier

    Dr Sylvie Bertholet

  16. Vaccine-mediated B cells responses to S. aureus hemolysin, and effect of different boosting intervals on functional humoral responses

    Article • Frontiers in Immunology, January 2013, Frontiers

    Dr Sylvie Bertholet

  17. Impact of vaccination route and chosen adjuvant on immune responses and host-pathogen interplay during influenza infection.

    Article • Frontiers in Immunology, January 2013, Frontiers

    Dr Sylvie Bertholet

  18. Evaluation of immune responses to a Plasmodium vivax CSP-based recombinant protein vaccine candidate in combination with second-generation adjuvants in mice

    Article • Vaccine, May 2012, Elsevier

    Dr Sylvie Bertholet

  19. Inferring Reasons for the Failure of Staphylococcus aureus Vaccines in Clinical Trials

    Article • Frontiers in Cellular and Infection Microbiology, January 2012, Frontiers

    Dr Sylvie Bertholet

  20. Malaria vaccine candidate: Design of a multivalent subunit α-helical coiled coil poly-epitope

    Article • Vaccine, September 2011, Elsevier

    Dr Sylvie Bertholet

  21. Development and Characterization of Synthetic Glucopyranosyl Lipid Adjuvant System as a Vaccine Adjuvant

    Article • PLoS ONE, January 2011, PLOS

    Dr Sylvie Bertholet

  22. A Synthetic Adjuvant to Enhance and Expand Immune Responses to Influenza Vaccines

    Article • PLoS ONE, October 2010, PLOS

    Dr Robert E Hancock, Dr Sylvie Bertholet

  23. A clinical trial to evaluate the safety and immunogenicity of the LEISH-F1+MPL-SE vaccine when used in combination with sodium stibogluconate for the treatment of mucosal leishmaniasis

    Article • Vaccine, October 2010, Elsevier

    Dr Sylvie Bertholet

  24. Optimized subunit vaccine protects against experimental leishmaniasis

    Article • Vaccine, November 2009, Elsevier

    Dr Sylvie Bertholet

  25. Enhanced humoral and Type 1 cellular immune responses with Fluzone® adjuvanted with a synthetic TLR4 agonist formulated in an emulsion

    Article • Vaccine, October 2009, Elsevier

    Dr Sylvie Bertholet

  26. Intradermal immunization improves protective efficacy of a novel TB vaccine candidate

    Article • Vaccine, May 2009, Elsevier

    Dr Sylvie Bertholet

  27. Leishmania infantum sterol 24-c-methyltransferase formulated with MPL-SE induces cross-protection against L. major infection

    Article • Vaccine, May 2009, Elsevier

    Dr Sylvie Bertholet

  28. New horizons in adjuvants for vaccine development

    Article • Trends in Immunology, January 2009, Elsevier

    Dr Sylvie Bertholet

  29. Protective immunization against visceral leishmaniasis using Leishmania sterol 24-c-methyltransferase formulated in adjuvant

    Article • Vaccine, October 2007, Elsevier

    Dr Sylvie Bertholet

  30. Impairment of Brucella growth in human macrophagic cells that produce nitric oxide

    Article • Microbial Pathogenesis, February 2004, Elsevier

    Dr Sylvie Bertholet

  31. Phagosomes are competent organelles for antigen cross-presentation

    Article • September 2003, Nature

    Dr Sylvie Bertholet

  32. Programmed cell death in trypanosomatids and other unicellular organisms

    Article • International Journal for Parasitology, March 2003, Elsevier

    Dr Sylvie Bertholet

  33. Rubella Virus Capsid Protein Induces Apoptosis in Transfected RK13 Cells

    Article • Virology, September 2000, Elsevier

    Dr Sylvie Bertholet

  34. Cytotoxic T lymphocyte responses to wild-type and mutant mouse p53 peptides

    Article • European Journal of Immunology, March 1997, Wiley

    Dr Sylvie Bertholet