All Stories

  1. Review of Published Bitter Orange Extract and p-Synephrine Adverse Event Clinical Study Case Reports
  2. How a polyphenolic mixture reduces hyperglycemic effects generated by Streptozotocin in vivo?
  3. Anti‐diabetic and Anti‐hyperlipidemic Effects and Safety of Salacia reticulata and Related Species
  4. Metal Antagonists
  5. Hepatocellular carcinoma and microRNA: New perspectives on therapeutics and diagnostics
  6. Preface
  7. ADRs, ADEs and SEDs
  8. Antiprotozoal Drugs
  9. Corticotrophins, Corticosteroids, and Prostaglandins
  10. Antiviral Drugs
  11. Cytostatic Agents
  12. Preface
  13. Metal Antagonists
  14. Associate Editors
  15. Doxorubicin-Induced In Vivo Nephrotoxicity Involves Oxidative Stress- Mediated Multiple Pro- and Anti-Apoptotic Signaling Pathways
  16. A Review and Evaluation of the Efficacy and Safety ofCissus quadrangularisExtracts
  17. Vendor Management – How Do You Score Your Vendors?
  18. Matrix metalloproteinase-9, -10, and -12, MDM2 and p53 expression in mouse liver during dimethylnitrosamine-induced oxidative stress and genomic injury
  19. Curcumin Exposure Modulates Multiple Pro-Apoptotic and Anti-Apoptotic Signaling Pathways to Antagonize Acetaminophen-Induced Toxicity
  20. Oxidative Toxicity in Neurodegenerative Diseases: Role of Mitochondrial Dysfunction and Therapeutic Strategies
  21. Silymarin modulates doxorubicin-induced oxidative stress, Bcl-xL and p53 expression while preventing apoptotic and necrotic cell death in the liver
  22. The Degree of Oxidative Stress Induced by Bioactivation-dependent Hepatotoxins Presage the Mediation of Caspase-activated DNAse (CAD)-dependent DNA Fragmentation and Cyt c Release to Propel Apoptotic and Necrotic Cell Deaths in the Liver in vivo
  23. A Novel Dietary Supplement Containing Multiple Phytochemicals and Vitamins Elevates Hepatorenal and Cardiac Antioxidant Enzymes in the Absence of Significant Serum Chemistry and Genomic Changes
  24. Cell Death and Apoptosis
  25. Bicarbonate Plus Epinephrine Shortens the Onset and Prolongs the Duration of Sciatic Block Using Chloroprocaine Followed by Bupivacaine in Sprague-Dawley Rats
  26. Synergy of pancratistatin and tamoxifen in inducing apoptosis in breast cancer cells
  27. Long term exposure effect of a unique metabolic nutrition system containing a diverse group of phytochemicals on serum chemistry and genomic and non-genomic changes in the liver of female B6C3F1 mice
  28. Pre-exposure to a novel nutritional mixture containing a series of phytochemicals prevents acetaminophen-induced programmed and unprogrammed cell deaths by enhancing BCL-XL expression and minimizing oxidative stress in the liver
  29. Prevention of Drug-Induced Programmed and Unprogrammed Cell Death by Citrus Flavonoids
  30. Proanthocyanidin exposure to B6C3F1 mice significantly attenuates dimethylnitrosamine-induced liver tumor induction and mortality by differentially modulating programmed and unprogrammed cell deaths
  31. Short-term and long-term in vivo exposure to an ephedra- and caffeine-containing metabolic nutrition system does not induce cardiotoxicity in B6C3F1 mice
  32. Apoptosis
  33. N-Nitrosodimethylamine
  34. Roles of Polyphenols, Flavonoids, and Oligomeric Proanthocyanidins in Cancer Chemoprevention
  35. Molecular mechanisms of cardioprotection by a novel grape seed proanthocyanidin extract
  36. Cellular Protection with Proanthocyanidins Derived from Grape Seeds
  37. Ca2+-calmodulin antagonist chlorpromazine and poly(ADP-ribose) polymerase modulators 4-aminobenzamide and nicotinamide influence hepatic expression of BCL-XL and P53 and protect against acetaminophen-induced programmed and unprogrammed cell death in mice
  38. Free radicals and grape seed proanthocyanidin extract: importance in human health and disease prevention
  39. A hepatotoxic dose of acetaminophen modulates expression of BCL-2, BCL-X L , and BCL-X S during apoptotic and necrotic death of mouse liver cells in vivo
  40. A Novel Proanthocyanidin IH636 Grape Seed Extract Increases in Vivo Bcl-Xl Expression and Prevents Acetaminophen-Induced Programmed and Unprogrammed Cell Death in Mouse Liver
  41. Protective effects of zinc salts on TPA-induced hepatic and brain lipid peroxidation, glutathione depletion, DNA damage and peritoneal macrophage activation in mice
  42. Cholesteryl hemisuccinate treatment protects rodents from the toxic effects of acetaminophen, adriamycin, carbon tetrachloride, chloroform and galactosamine
  43. Tetrahydroaminoacridine-induced ribosomal changes and inhibition of protein synthesis in rat hepatocyte suspensions
  44. Induction of P4502E1 by acetone in isolated rabbit hepatocytes
  45. DMBA Induces Programmed Cell Death (Apoptosis) in the A20.1 Murine B Cell Lymphoma
  46. The role of the nucleus and other compartments in toxic cell death produced by alkylating hepatotoxicants
  47. DMBA-induced cytotoxicity in lymphoid and nonlymphoid organs of B6C3F1 mice: Relation of cell death to target cell intracellular calcium and DNA damage
  48. Acetaminophen-induced cytotoxicity in cultured mouse hepatocytes: Effects of Ca2+-endonuclease, DNA repair, and glutathione depletion inhibitors on DNA fragmentation and cell death
  49. Acetaminophen-induced cytotoxicity in cultured mouse hepatocytes: Correlation of nuclear Ca2+ accumulation and early DNA fragmentation with cell death
  50. Extensive Alteration of Genomic DNA and Rise in Nuclear Ca2+ in Vivo Early after Hepatotoxic Acetaminophen Overdose in Mice
  51. Early loss of large genomic DNA in vivo with accumulation of Ca2+ in the nucleus during acetaminophen-induced liver injury
  52. Potentiation of CCl 4 and CHCl 3 Hepatotoxicity and Lethality by Various Alcohols
  53. Reversible and irreversible inhibition of hepatic mitochondrial respiration by acetaminophen and its toxic metabolite, N-acetyl-p-benzoquinoneimine (NAPQI)