All Stories

  1. Cotinine Enhances Fear Extinction and Astrocyte Survival by Mechanisms Involving the Nicotinic Acetylcholine Receptors Signaling

    Article • Frontiers in Pharmacology, April 2020, Frontiers

    Dr Valentina Echeverria

  2. Strategies for the Treatment of Parkinson’s Disease: Beyond Dopamine

    Article • Frontiers in Aging Neuroscience, January 2020, Frontiers

    Dr Valentina Echeverria

  3. Lipotoxicity, neuroinflammation, glial cells and oestrogenic compounds

    Article • Journal of Neuroendocrinology, August 2019, Wiley

    Dr Valentina Echeverria

  4. Secretome of Mesenchymal Stem Cells and Its Potential Protective Effects on Brain Pathologies

    Article • Molecular Neurobiology, April 2019, Springer Science + Business Media

    Dr Valentina Echeverria

  5. Tibolone attenuates inflammatory response by palmitic acid and preserves mitochondrial membrane potential in astrocytic cells through estrogen receptor beta

    Article • Molecular and Cellular Endocrinology, February 2019, Elsevier

    Professor Diego A Forero, Dr Valentina Echeverria

  6. Molecular mechanisms involved in the protective actions of Selective Estrogen Receptor Modulators in brain cells

    Article • Frontiers in Neuroendocrinology, January 2019, Elsevier

    Dr Valentina Echeverria

  7. Mitochondrial Neuroglobin Is Necessary for Protection Induced by Conditioned Medium from Human Adipose-Derived Mesenchymal Stem Cells in Astrocytic Cells Subjected to Scratch and Metabolic Injury

    Article • Molecular Neurobiology, December 2018, Springer Science + Business Media

    Dr Valentina Echeverria

  8. Astrocytes Mediate Protective Actions of Estrogenic Compounds after Traumatic Brain Injury

    Article • Neuroendocrinology, November 2018, Karger Publishers

    Dr Valentina Echeverria

  9. Raloxifene attenuates oxidative stress and preserves mitochondrial function in astrocytic cells upon glucose deprivation

    Article • Journal of Cellular Physiology, September 2018, Wiley

    Dr Valentina Echeverria

  10. Correction to: Growth Factors and Neuroglobin in Astrocyte Protection Against Neurodegeneration and Oxidative Stress

    Article • Molecular Neurobiology, July 2018, Springer Science + Business Media

    Dr Valentina Echeverria

  11. Growth Factors and Neuroglobin in Astrocyte Protection Against Neurodegeneration and Oxidative Stress

    Article • Molecular Neurobiology, July 2018, Springer Science + Business Media

    Dr Valentina Echeverria

  12. (E)-Nicotinaldehyde O-Cinnamyloxime, a Nicotine Analog, Attenuates Neuronal Cells Death Against Rotenone-Induced Neurotoxicity

    Article • Molecular Neurobiology, June 2018, Springer Science + Business Media

    Dr Valentina Echeverria

  13. Correction to: Intranasal Cotinine Plus Krill Oil Facilitates Fear Extinction, Decreases Depressive-Like Behavior, and Increases Hippocampal Calcineurin A Levels in Mice

    Article • Molecular Neurobiology, April 2018, Springer Science + Business Media

    Dr Valentina Echeverria

  14. Correction to: Cotinine: A Therapy for Memory Extinction in Post-traumatic Stress Disorder

    Article • Molecular Neurobiology, April 2018, Springer Science + Business Media

    Dr Valentina Echeverria, Gjumrakch Aliev

  15. Intranasal Cotinine Plus Krill Oil Facilitates Fear Extinction, Decreases Depressive-Like Behavior, and Increases Hippocampal Calcineurin A Levels in Mice

    Article • Molecular Neurobiology, February 2018, Springer Science + Business Media

    Dr Valentina Echeverria

  16. Cotinine: A Therapy for Memory Extinction in Post-traumatic Stress Disorder

    Article • Molecular Neurobiology, January 2018, Springer Science + Business Media

    Dr Valentina Echeverria, Gjumrakch Aliev

  17. Approaches of the Transcriptomic Analysis in Astrocytes: Potential Pharmacological Targets

    Article • Current Pharmaceutical Design, November 2017, Bentham Science Publishers

    Professor Diego A Forero, Gjumrakch Aliev, Dr Valentina Echeverria, jerzy leszek

  18. Medicinal Plants as Protective Strategies Against Parkinson's Disease

    Article • Current Pharmaceutical Design, November 2017, Bentham Science Publishers

    Dr Valentina Echeverria, Gjumrakch Aliev

  19. Is VEGF a Key Target of Cotinine and Other Potential Therapies Against Alzheimer Disease?

    Article • Current Alzheimer Research, October 2017, Bentham Science Publishers

    Gjumrakch Aliev, Dr Valentina Echeverria

  20. Intranasal cotinine improves memory, and reduces depressive-like behavior, and GFAP + cells loss induced by restraint stress in mice

    Article • Experimental Neurology, September 2017, Elsevier

    Dr Valentina Echeverria

  21. Cotinine improves visual recognition memory and decreases cortical Tau phosphorylation in the Tg6799 mice

    Article • Progress in Neuro-Psychopharmacology and Biological Psychiatry, August 2017, Elsevier

    Dr Valentina Echeverria

  22. Post-treatment with cotinine improved memory and decreased depressive-like behavior after chemotherapy in rats

    Article • Cancer Chemotherapy and Pharmacology, October 2016, Springer Science + Business Media

    Dr Valentina Echeverria

  23. Role of neuroinflammation and sex hormones in war-related PTSD

    Article • Molecular and Cellular Endocrinology, October 2016, Elsevier

    Dr Valentina Echeverria

  24. Positive modulators of the α7 nicotinic receptor against neuroinflammation and cognitive impairment in Alzheimer's disease

    Article • Progress in Neurobiology, September 2016, Elsevier

    Dr Valentina Echeverria, Gjumrakch Aliev

  25. Growth Factors and Astrocytes Metabolism: Possible Roles for Platelet Derived Growth Factor

    Article • Medicinal Chemistry, March 2016, Bentham Science Publishers

    Dr Valentina Echeverria, Gjumrakch Aliev

  26. Implication of Green Tea as a Possible Therapeutic Approach for Parkinson Disease

    Article • CNS & Neurological Disorders - Drug Targets, March 2016, Bentham Science Publishers

    Dr Valentina Echeverria

  27. Neuroinflammation: A Therapeutic Target of Cotinine for the Treatment of Psychiatric Disorders?

    Article • Current Pharmaceutical Design, March 2016, Bentham Science Publishers

    Dr Valentina Echeverria

  28. Targeting the Nicotinic Acetylcholine Receptors (nAChRs) in Astrocytes as a Potential Therapeutic Target in Parkinson's Disease

    Article • Current Pharmaceutical Design, March 2016, Bentham Science Publishers

    Dr Valentina Echeverria

  29. Editorial (Thematic Issue: Neuroinflammation a Common Link in Neurodegenerative Neurological and Psychiatric Disorders)

    Article • Current Pharmaceutical Design, March 2016, Bentham Science Publishers

    Dr Valentina Echeverria

  30. Microglial dependent protective effects of neuroactive steroids

    Article • CNS & Neurological Disorders - Drug Targets, February 2016, Bentham Science Publishers

    Dr Valentina Echeverria

  31. Nanoparticles as Alternative Strategies for Drug Delivery to the Alzheimer Brain: Electron Microscopy Ultrastructural Analysis

    Article • CNS & Neurological Disorders - Drug Targets, November 2015, Bentham Science Publishers

    Dr Valentina Echeverria, Gjumrakch Aliev

  32. Smoking and PTSD

    Article • Current Pharmaceutical Design, August 2015, Bentham Science Publishers

    Dr Valentina Echeverria, Gjumrakch Aliev

  33. Beneficial effects of nicotine, cotinine and its metabolites as potential agents for Parkinson’s disease

    Article • Frontiers in Aging Neuroscience, January 2015, Frontiers

    Dr Valentina Echeverria

  34. Cotinine prevents memory loss and diminishes Alzheimer's disease-like pathology

    Article • Frontiers in Cellular Neuroscience, January 2015, Frontiers

    Dr Valentina Echeverria

  35. Nicotine analogues as potential therapeutic agents in Parkinson’s disease by targeting nicotinic acetylcholine receptors (nAChRs) in astrocytes

    Article • Frontiers in Cellular Neuroscience, January 2015, Frontiers

    Dr Valentina Echeverria

  36. Cotinine halts the advance of Alzheimer's disease-like pathology and associated depressive-like behavior in Tg6799 mice

    Article • Frontiers in Aging Neuroscience, July 2014, Frontiers

    Dr Valentina Echeverria

  37. Cotinine reduces depressive-like behavior, working memory deficits, and synaptic loss associated with chronic stress in mice

    Article • Behavioural Brain Research, July 2014, Elsevier

    Dr Valentina Echeverria

  38. New Insights into the Mechanisms of Action of Cotinine and its Distinctive Effects from Nicotine

    Article • Neurochemical Research, June 2014, Springer Science + Business Media

    Dr Valentina Echeverria

  39. Cotinine reduces depressive-like behavior and hippocampal vascular endothelial growth factor downregulation after forced swim stress in mice.

    Article • Behavioral Neuroscience, January 2014, American Psychological Association (APA)

    Dr Valentina Echeverria

  40. Brain effects of Nicotine and derived compounds

    Article • January 2013, Frontiers

    Dr Valentina Echeverria

  41. Brain effects of nicotine and derived compounds

    Article • Frontiers in Pharmacology, January 2013, Frontiers

    Dr Valentina Echeverria

  42. Cotinine: A Potential New Therapeutic Agent against Alzheimer's disease

    Article • CNS Neuroscience & Therapeutics, April 2012, Wiley

    Dr Valentina Echeverria

  43. Cotinine enhances the extinction of contextual fear memory and reduces anxiety after fear conditioning

    Article • Behavioural Brain Research, March 2012, Elsevier

    Dr Valentina Echeverria

  44. Cotinine: Beyond that Expected, More than a Biomarker of Tobacco Consumption

    Article • Frontiers in Pharmacology, January 2012, Frontiers

    Dr Valentina Echeverria

  45. Caffeine induces beneficial changes in PKA signaling and JNK and ERK activities in the striatum and cortex of Alzheimer's transgenic mice

    Article • Brain Research, October 2011, Elsevier

    Dr Valentina Echeverria

  46. Cotinine Reduces Amyloid-β Aggregation and Improves Memory in Alzheimer's Disease Mice

    Article • Journal of Alzheimer s Disease, May 2011, IOS Press

    Dr Valentina Echeverria

  47. Cotinine: A dual-action drug with multiple benefits against Alzheimer's disease

    Article • Alzheimer s & Dementia, July 2010, Elsevier

    Dr Valentina Echeverria

  48. Raf Inhibitors as Therapeutic Agents Against Neurodegenerative Diseases

    Article • CNS & Neurological Disorders - Drug Targets, March 2010, Bentham Science Publishers

    Dr Valentina Echeverria

  49. Sorafenib inhibits nuclear factor kappa B, decreases inducible nitric oxide synthase and cyclooxygenase-2 expression, and restores working memory in APPswe mice

    Article • Neuroscience, September 2009, Elsevier

    Dr Valentina Echeverria

  50. Caffeine Reverses Cognitive Impairment and Decreases Brain Amyloid-β Levels in Aged Alzheimer's Disease Mice

    Article • Journal of Alzheimer s Disease, July 2009, IOS Press

    Dr Valentina Echeverria

  51. Raf inhibition protects cortical cells against β-amyloid toxicity

    Article • Neuroscience Letters, October 2008, Elsevier

    Dr Valentina Echeverria

  52. Transcription factor Sp1 dysregulation in Alzheimer's disease

    Article • Journal of Neuroscience Research, August 2008, Wiley

    Dr Valentina Echeverria

  53. P2-319: Cotinine is neuroprotective against beta-amyloid toxicity

    Article • Alzheimer s & Dementia, July 2008, Elsevier

    Dr Valentina Echeverria

  54. P4-303: Sorafenib as a therapeutic agent against Alzheimer's disease

    Article • Alzheimer s & Dementia, July 2008, Elsevier

    Dr Valentina Echeverria

  55. Expression of Prostaglandin E2 Synthases in Mouse Postnatal Cortical Neurons

    Article • Annals of the New York Academy of Sciences, June 2008, Wiley

    Dr Valentina Echeverria

  56. Oligomers of β-Amyloid Peptide Inhibit BDNF-Induced Arc Expression in Cultured Cortical Neurons

    Article • Current Alzheimer Research, December 2007, Bentham Science Publishers

    Dr Valentina Echeverria

  57. Stimulation of Prostaglandin EP2 Receptors Prevents NMDA-Induced Excitotoxicity

    Article • Journal of Neurotrauma, December 2006, Mary Ann Liebert Inc

    Dr Valentina Echeverria, Sylvain Dore

  58. 1-HydroxyPGE1reduces infarction volume in mouse transient cerebral ischemia

    Article • European Journal of Neuroscience, January 2006, Wiley

    Dr Valentina Echeverria, Sylvain Dore

  59. Stimulation of PGE2receptors EP2 and EP4 protects cultured neurons against oxidative stress and cell death following β-amyloid exposure

    Article • European Journal of Neuroscience, November 2005, Wiley

    Dr Valentina Echeverria, Sylvain Dore

  60. Expression of Prostaglandin E2 Synthases in Mouse Postnatal Cortical Neurons

    Article • Annals of the New York Academy of Sciences, August 2005, Wiley

    Dr Valentina Echeverria, Sylvain Dore

  61. Endogenous β-amyloid peptide synthesis modulates cAMP response element-regulated gene expression in PC12 cells

    Article • Neuroscience, January 2005, Elsevier

    Dr Valentina Echeverria

  62. Altered mitogen-activated protein kinase signaling, tau hyperphosphorylation and mild spatial learning dysfunction in transgenic rats expressing the β-amyloid peptide intracellularly in hippocampal and cortical neurons

    Article • Neuroscience, January 2004, Elsevier

    Dr Valentina Echeverria

  63. Intracellular A-Beta Amyloid, A Sign for Worse Things to Come?

    Article • Molecular Neurobiology, January 2002, Springer Science + Business Media

    Dr Valentina Echeverria

  64. The DREAM–DRE interaction: key nucleotides and dominant negative mutants

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, December 2000, Elsevier

    Dr Valentina Echeverria, Jose Naranjo

  65. Mutagenesis in the switch IV of the helical domain of the human Gsα reduces its GDP/GTP exchange rate

    Article • Journal of Cellular Biochemistry, March 2000, Wiley

    Dr Valentina Echeverria

  66. The C2 cytosolic loop of adenylyl cyclase interacts with the activated form of Gαs

    Article • FEBS Letters, December 1998, Wiley

    Dr Valentina Echeverria

  67. Molecular cloning and expression of an adenylyl cyclase from Xenopus laevis oocytes 1

    Article • FEBS Letters, March 1997, Wiley

    Dr Valentina Echeverria