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  1. Natural Products That Changed Society

    Article • Biomedicines, April 2021, MDPI AG

    Professor Søren Brøgger Christensen

  2. Targeting Toxins toward Tumors

    Article • Molecules, February 2021, MDPI AG

    Professor Søren Brøgger Christensen

  3. From Plant to Patient: Thapsigargin, a Tool for Understanding Natural Product Chemistry, Total Syntheses, Biosynthesis, Taxonomy, ATPases, Cell Death, and Drug Development

    Article • January 2021, Springer Science + Business Media

    Professor Søren Brøgger Christensen

  4. Large Scale Conversion of Trilobolide into the Payload of Mipsagargin: 8-O-(12-Aminododecanoyl)-8-O-Debutanoylthapsigargin

    Article • Biomolecules, December 2020, MDPI AG

    Professor Søren Brøgger Christensen

  5. Cell death induced by the ER stressor thapsigargin involves death receptor 5, a non-autophagic function of MAP1LC3B, and distinct contributions from unfolded protein response components

    Article • Cell Communication and Signaling, January 2020, Springer Science + Business Media

    Professor Søren Brøgger Christensen

  6. Missing Selectivity of Targeted 4β-Phorbol Prodrugs Expected to be Potential Chemotherapeutics

    Article • ACS Medicinal Chemistry Letters, December 2019, American Chemical Society (ACS)

    Virpi Talman, Professor Søren Brøgger Christensen

  7. Biosynthesis of tovarol and other sesquiterpenoids in Thapsia laciniata Rouy

    Article • Phytochemistry, January 2019, Elsevier

    Professor Søren Brøgger Christensen

  8. Nonlinear relationship between ER Ca2+ depletion versus induction of the unfolded protein response, autophagy inhibition, and cell death

    Article • Cell Calcium, December 2018, Elsevier

    Professor Søren Brøgger Christensen

  9. Phorbol Rearrangements

    Article • Journal of Natural Products, September 2018, American Chemical Society (ACS)

    Professor Søren Brøgger Christensen

  10. Preparation of Enzyme-Activated Thapsigargin Prodrugs by Solid-Phase Synthesis

    Article • Molecules, June 2018, MDPI AG

    Professor Søren Brøgger Christensen

  11. A new flavonol glycoside and other flavonoids from the aerial parts of Taverniera aegyptiaca

    Article • Natural Product Research, April 2018, Taylor & Francis

    Professor Søren Brøgger Christensen

  12. Cover Feature: LEGO-Inspired Drug Design: Unveiling a Class of Benzo[d ]thiazoles Containing a 3,4-Dihydroxyphenyl Moiety as Plasma Membrane H+ -ATPase Inhibitors (ChemMedChem 1/2018)

    Article • ChemMedChem, January 2018, Wiley

    Professor Søren Brøgger Christensen, Professor Anja Thoe Fuglsang

  13. LEGO-Inspired Drug Design: Unveiling a Class of Benzo[d ]thiazoles Containing a 3,4-Dihydroxyphenyl Moiety as Plasma Membrane H+ -ATPase Inhibitors

    Article • ChemMedChem, December 2017, Wiley

    Professor Søren Brøgger Christensen, Professor Anja Thoe Fuglsang

  14. Cover Feature: Difluoroacetic Acid as a New Reagent for Direct C−H Difluoromethylation of Heteroaromatic Compounds (Chem. Eur. J. 72/2017)

    Article • Chemistry - A European Journal, October 2017, Wiley

    Professor Søren Brøgger Christensen

  15. Difluoroacetic Acid as a New Reagent for Direct C−H Difluoromethylation of Heteroaromatic Compounds

    Article • Chemistry - A European Journal, October 2017, Wiley

    Professor Søren Brøgger Christensen

  16. Inhibition of the sarco/endoplasmic reticulum (ER) Ca2+-ATPase by thapsigargin analogs induces cell death via ER Ca2+depletion and the unfolded protein response

    Article • Journal of Biological Chemistry, September 2017, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Søren Brøgger Christensen

  17. Metformin, an Anthropogenic Contaminant of Seidlitzia rosmarinus Collected in a Desert Region near the Gulf of Aqaba, Sinai Peninsula

    Article • Journal of Natural Products, September 2017, American Chemical Society (ACS)

    Professor Søren Brøgger Christensen

  18. Accelerating the Domestication of New Crops: Feasibility and Approaches

    Article • Trends in Plant Science, May 2017, Elsevier

    Professor Søren Brøgger Christensen

  19. Cranberry Juice and Combinations of Its Organic Acids Are Effective against Experimental Urinary Tract Infection

    Article • Frontiers in Microbiology, April 2017, Frontiers

    Professor Søren Brøgger Christensen

  20. Localization and in-Vivo Characterization of Thapsia garganica CYP76AE2 Indicates a Role in Thapsigargin Biosynthesis

    Article • PLANT PHYSIOLOGY, March 2017, American Society of Plant Biologists (ASPB)

    Professor Søren Brøgger Christensen

  21. Structure/activity relationship of thapsigargin inhibition on the purified Golgi/secretory pathway Ca 2+ /Mn 2+ -transport ATPase (SPCA1a)

    Article • Journal of Biological Chemistry, March 2017, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Søren Brøgger Christensen

  22. Fusaric acid and analogues as Gram-negative bacterial quorum sensing inhibitors

    Article • European Journal of Medicinal Chemistry, January 2017, Elsevier

    Professor Søren Brøgger Christensen, Professor Anja Thoe Fuglsang

  23. Demethoxycurcumin Is A Potent Inhibitor of P-Type ATPases from Diverse Kingdoms of Life

    Article • PLoS ONE, September 2016, PLOS

    Professor Søren Brøgger Christensen, Professor Anja Thoe Fuglsang

  24. Iminolactones as tools for inversion of the absolute configuration of α-amino acids and as inhibitors of cancer cell proliferation

    Article • European Journal of Medicinal Chemistry, May 2016, Elsevier

    Professor Søren Brøgger Christensen

  25. Meet Our Editorial Board Member

    Article • Anti-Cancer Agents in Medicinal Chemistry, February 2016, Bentham Science Publishers

    Professor Søren Brøgger Christensen

  26. Thapsigargin, origin, chemistry, structure-activity relationships and prodrug development

    Article • Current Pharmaceutical Design, November 2015, Bentham Science Publishers

    Professor Søren Brøgger Christensen

  27. Concise synthesis of thapsigargin from nortrilobolide

    Article • Tetrahedron Letters, October 2015, Elsevier

    Professor Søren Brøgger Christensen

  28. Chemo- and Regioselective Functionalization of Nortrilobolide: Application for Semisynthesis of the Natural Product 2-Acetoxytrilobolide

    Article • Journal of Natural Products, June 2015, American Chemical Society (ACS)

    Professor Søren Brøgger Christensen

  29. Iminolactones from Schizophyllum commune

    Article • Journal of Natural Products, May 2015, American Chemical Society (ACS)

    Professor Søren Brøgger Christensen

  30. Targeting thapsigargin towards tumors

    Article • Steroids, May 2015, Elsevier

    Professor Søren Brøgger Christensen

  31. Are we ready for back-to-nature crop breeding?

    Article • Trends in Plant Science, March 2015, Elsevier

    Professor Søren Brøgger Christensen

  32. Drugs and Drug Leads Based on Natural Products for Treatment and Prophylaxis of Malaria

    Article • January 2015, Elsevier

    Professor Søren Brøgger Christensen

  33. Contributors

    Article • January 2015, Elsevier

    Professor Søren Brøgger Christensen

  34. Differential effects of thapsigargin analogues on apoptosis of prostate cancer cells

    Article • FEBS Journal, September 2013, Wiley

    Professor Søren Brøgger Christensen

  35. Serotonin transporter protein (SERT) and P-glycoprotein (P-gp) binding activity of montanine and coccinine from three species of Haemanthus L. (Amaryllidaceae)

    Article • South African Journal of Botany, September 2013, Elsevier

    Professor Søren Brøgger Christensen

  36. Water-Mediated Interactions Influence the Binding of Thapsigargin to Sarco/Endoplasmic Reticulum Calcium Adenosinetriphosphatase

    Article • Journal of Medicinal Chemistry, May 2013, American Chemical Society (ACS)

    Professor Søren Brøgger Christensen

  37. Guaianolide Sesquiterpenoids: Pharmacology and Biosynthesis

    Article • January 2013, Springer Science + Business Media

    Professor Søren Brøgger Christensen

  38. Alkaloid analysis by high-performance liquid chromatography-solid phase extraction-nuclear magnetic resonance: New strategies going beyond the standard

    Article • Journal of Chromatography A, December 2012, Elsevier

    Professor Søren Brøgger Christensen

  39. A Correction to the Research Article Titled: "Engineering a Prostate-Specific Membrane Antigen-Activated Tumor Endothelial Cell Prodrug for Cancer Therapy" by S. R. Denmeade, A. M. Mhaka, D. Marc Rosen, W. N. Brennen, S. Dalrymple, I. Dach, C. Olesen, ...

    Article • Science Translational Medicine, July 2012, American Association for the Advancement of Science

    Professor Søren Brøgger Christensen

  40. Chalcone inhibitors of the NorA efflux pump in Staphylococcus aureus whole cells and enriched everted membrane vesicles

    Article • Bioorganic & Medicinal Chemistry, July 2012, Elsevier

    Professor Søren Brøgger Christensen

  41. Engineering a Prostate-Specific Membrane Antigen-Activated Tumor Endothelial Cell Prodrug for Cancer Therapy

    Article • Science Translational Medicine, June 2012, American Association for the Advancement of Science

    Professor Søren Brøgger Christensen

  42. Novel inhibitory activity of the Staphylococcus aureus NorA efflux pump by a kaempferol rhamnoside isolated from Persea lingue Nees

    Article • Journal of Antimicrobial Chemotherapy, February 2012, Oxford University Press (OUP)

    Professor Søren Brøgger Christensen

  43. 6-O-Methylkrigeine, a new Amaryllidaceae alkaloid fromNerine huttoniaeSchönland

    Article • Natural Product Research, January 2012, Taylor & Francis

    Professor Søren Brøgger Christensen

  44. Can phylogeny predict chemical diversity and potential medicinal activity of plants? A case study of amaryllidaceae

    Article • BMC Evolutionary Biology, January 2012, Springer Science + Business Media

    Dr Alan W Meerow, Professor Søren Brøgger Christensen

  45. Obituary – Professor Dr. Jerzy Jaroszewski

    Article • Planta Medica, November 2011, Thieme Publishing Group

    Professor Søren Brøgger Christensen

  46. Oleic and linoleic acids are active principles in Nigella sativa and stabilize an E2P conformation of the Na,K-ATPase. Fatty acids differentially regulate cardiac glycoside interaction with the pump

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, October 2011, Elsevier

    Professor Søren Brøgger Christensen

  47. Amaryllidaceae alkaloids from Rauhia multiflora (Kunth) Ravenna

    Article • Planta Medica, August 2011, Thieme Publishing Group

    Professor Søren Brøgger Christensen

  48. Thapsigargin affinity purification of intracellular P2A-type Ca2+ ATPases

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, May 2011, Elsevier

    Professor Søren Brøgger Christensen

  49. Amaryllidaceae alkaloids from the Australasian tribe Calostemmateae with acetylcholinesterase inhibitory activity

    Article • Biochemical Systematics and Ecology, April 2011, Elsevier

    Professor Søren Brøgger Christensen

  50. Isolation of immunomodulatory triterpene acids from a standardized rose hip powder (Rosa canina L.)

    Article • Phytotherapy Research, February 2011, Wiley

    Professor Søren Brøgger Christensen

  51. Characterization of anti-inflammatory triterpene acids from rose hip powder (Rosa canina L.)

    Article • Planta Medica, August 2010, Thieme Publishing Group

    Professor Søren Brøgger Christensen

  52. The pharmacophore of thapsigargin

    Article • Planta Medica, August 2010, Thieme Publishing Group

    Professor Søren Brøgger Christensen

  53. Elucidation of the topography of the thapsigargin binding site in the sarco-endoplasmic calcium ATPase

    Article • Bioorganic & Medicinal Chemistry, August 2010, Elsevier

    Professor Søren Brøgger Christensen

  54. Critical Roles of Hydrophobicity and Orientation of Side Chains for Inactivation of Sarcoplasmic Reticulum Ca2+-ATPase with Thapsigargin and Thapsigargin Analogs

    Article • Journal of Biological Chemistry, June 2010, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Søren Brøgger Christensen

  55. Structure–activity relationships of a small-molecule inhibitor of the PDZ domain of PICK1

    Article • Organic & Biomolecular Chemistry, January 2010, Royal Society of Chemistry

    Professor Søren Brøgger Christensen

  56. A Phenylpropanoid, a Slovenolide, Two Sulphur-Containing Germacranes and Ca2+-ATPase Inhibitors fromThapsia villosa

    Article • Planta Medica, August 2009, Thieme Publishing Group

    Professor Søren Brøgger Christensen

  57. 19α-Hydroxy-3-oxo-ursa-1,12-dien-28-oic acid, an antiplasmodial triterpenoid isolated fromCanthium multiflorum

    Article • Natural Product Research, August 2009, Taylor & Francis

    Professor Søren Brøgger Christensen

  58. Amino acid containing thapsigargin analogues deplete androgen receptor protein via synthesis inhibition and induce the death of prostate cancer cells

    Article • Molecular Cancer Therapeutics, May 2009, American Association for Cancer Research (AACR)

    Professor Søren Brøgger Christensen, Dr. Donald Vander Griend

  59. A Trojan Horse in Drug Development: Targeting of Thapsigargins Towards Prostate Cancer Cells

    Article • Anti-Cancer Agents in Medicinal Chemistry, March 2009, Bentham Science Publishers

    Professor Søren Brøgger Christensen

  60. Systemic 7-methylxanthine in retarding axial eye growth and myopia progression: a 36-month pilot study

    Article • Journal of Ocular Biology Diseases and Informatics, November 2008, Springer Science + Business Media

    Professor Søren Brøgger Christensen

  61. S-petasin and butterbur lactones dilate vessels through blockage of voltage gated calcium channels and block DNA synthesis

    Article • European Journal of Pharmacology, September 2008, Elsevier

    Professor Søren Brøgger Christensen

  62. Isolation of the MAO-inhibitor naringenin from Mentha aquatica L.

    Article • Journal of Ethnopharmacology, May 2008, Elsevier

    Professor Søren Brøgger Christensen

  63. Isolation of linoleic andα-linolenic acids as COX-1 and -2 inhibitors in rose hip

    Article • Phytotherapy Research, April 2008, Wiley

    Professor Søren Brøgger Christensen

  64. A New Oxygenated Ursane Derivative from Canthium multiflorum

    Article • Planta Medica, April 2008, Thieme Publishing Group

    Professor Søren Brøgger Christensen

  65. Mild psychoactive constituents of Mentha aquatica L.

    Article • South African Journal of Botany, April 2008, Elsevier

    Professor Søren Brøgger Christensen

  66. Carroll rearrangement to construct the norneolignan skeleton

    Article • Natural Product Research, January 2008, Taylor & Francis

    Professor Søren Brøgger Christensen

  67. A configurational and conformational study of aframodial and its diasteriomers via experimental and theoretical VA and VCD spectroscopies

    Article • Theoretical Chemistry Accounts, October 2007, Springer Science + Business Media

    Professor Søren Brøgger Christensen

  68. Prenylated acetophenones from Melicope obscura and Melicope obtusifolia ssp. obtusifolia var. arborea and their distribution in Rutaceae

    Article • Biochemical Systematics and Ecology, July 2007, Elsevier

    Professor Søren Brøgger Christensen

  69. Isolation and characterization of pristimerin as the antiplasmodial and antileishmanial agent of Maytenus senegalensis (Lam.) Exell.

    Article • ARKIVOC, January 2007, ARKAT USA, Inc.

    Professor Søren Brøgger Christensen

  70. Identification of Natural Products Using HPLC-SPE Combined with CapNMR

    Article • Analytical Chemistry, January 2007, American Chemical Society (ACS)

    Professor Søren Brøgger Christensen

  71. Cytotoxic kurubasch aldehyde fromTrichilia emetica

    Article • Natural Product Research, January 2007, Taylor & Francis

    Professor Søren Brøgger Christensen

  72. Psychotropic constituents of Mentha aquatica L.

    Article • Planta Medica, January 2007, Thieme Publishing Group

    Professor Søren Brøgger Christensen

  73. Cytotoxic phenylpropanoids and an additional thapsigargin analogue isolated from Thapsia garganica

    Article • Phytochemistry, December 2006, Elsevier

    Professor Søren Brøgger Christensen

  74. Ancistrocladinium A and B, the First N,C-Coupled Naphthyldihydroisoquinoline Alkaloids, from a Congolese Ancistrocladus Species

    Article • The Journal of Organic Chemistry, November 2006, American Chemical Society (ACS)

    Professor Søren Brøgger Christensen

  75. Sesquiterpenes from Thapsia nitida var. meridionalis and Thapsia nitida var. nitida

    Article • Journal of Natural Products, November 2006, American Chemical Society (ACS)

    Professor Søren Brøgger Christensen

  76. Ethnopharmacological evaluation of radal (leaves of Lomatia hirsuta) and isolation of 2-methoxyjuglone

    Article • BMC Complementary and Alternative Medicine, August 2006, Springer Science + Business Media

    Professor Søren Brøgger Christensen

  77. Identification and evaluation of Peruvian plants used to treat malaria and leishmaniasis

    Article • Journal of Ethnopharmacology, July 2006, Elsevier

    Professor Søren Brøgger Christensen

  78. Natural products as starting materials for development of second-generation SERCA inhibitors targeted towards prostate cancer cells

    Article • Bioorganic & Medicinal Chemistry, April 2006, Elsevier

    Professor Søren Brøgger Christensen

  79. Pharmacokinetics, biodistribution, and antitumor efficacy of a human glandular kallikrein 2 (hK2)-activated thapsigargin prodrug

    Article • The Prostate, March 2006, Wiley

    Professor Søren Brøgger Christensen

  80. Antimalarial and Antiplasmodial Activities of Norneolignans. Syntheses and SAR

    Article • Journal of Medicinal Chemistry, January 2006, American Chemical Society (ACS)

    Professor Søren Brøgger Christensen

  81. Total Synthesis of Two Novel Subpicomolar Sarco/Endoplasmatic Reticulum Ca 2+ -ATPase Inhibitors Designed by an Analysis of the Binding Site of Thapsigargin

    Article • Journal of Medicinal Chemistry, November 2005, American Chemical Society (ACS)

    Professor Søren Brøgger Christensen

  82. Structure and Absolute Configuration of Nyasol and Hinokiresinol via Synthesis and Vibrational Circular Dichroism Spectroscopy

    Article • Journal of Natural Products, November 2005, American Chemical Society (ACS)

    Professor Søren Brøgger Christensen

  83. Applying Linear Interaction Energy Method for Rational Design of Noncompetitive Allosteric Inhibitors of the Sarco- and Endoplasmic Reticulum Calcium-ATPase

    Article • Journal of Medicinal Chemistry, April 2005, American Chemical Society (ACS)

    Professor Søren Brøgger Christensen

  84. The Antiparasitic Compound Licochalcone A Is a Potent Echinocytogenic Agent That Modifies the Erythrocyte Membrane in the Concentration Range Where Antiplasmodial Activity Is Observed

    Article • Antimicrobial Agents and Chemotherapy, October 2004, ASM Journals

    Professor Søren Brøgger Christensen

  85. Tethered Lipids fromThapsiagarganica

    Article • Journal of Natural Products, September 2004, American Chemical Society (ACS)

    Professor Søren Brøgger Christensen

  86. Synthesis of the thapsigargins

    Article • Proceedings of the National Academy of Sciences, June 2004, Proceedings of the National Academy of Sciences

    Professor Søren Brøgger Christensen

  87. Ancistrotanzanine C and Related 5,1‘- and 7,3‘-Coupled Naphthylisoquinoline Alkaloids fromAncistrocladustanzaniensis1

    Article • Journal of Natural Products, May 2004, American Chemical Society (ACS)

    Professor Søren Brøgger Christensen

  88. Antiplasmodial constituents ofCajanus cajan

    Article • Phytotherapy Research, February 2004, Wiley

    Professor Søren Brøgger Christensen

  89. Ancistrotanzanine A, the First 5,3‘-Coupled Naphthylisoquinoline Alkaloid, and Two Further, 5,8‘-Linked Related Compounds from the Newly Described SpeciesAncistrocladus tanzaniensis#,1

    Article • Journal of Natural Products, September 2003, American Chemical Society (ACS)

    Professor Søren Brøgger Christensen

  90. Prostate-Specific Antigen-Activated Thapsigargin Prodrug as Targeted Therapy for Prostate Cancer

    Article • JNCI Journal of the National Cancer Institute, July 2003, Oxford University Press (OUP)

    Professor Søren Brøgger Christensen

  91. An Antiinflammatory Galactolipid from Rose Hip (Rosacanina) that Inhibits Chemotaxis of Human Peripheral Blood Neutrophils in Vitro

    Article • Journal of Natural Products, July 2003, American Chemical Society (ACS)

    Professor Søren Brøgger Christensen

  92. An Antiplasmodial Lignan fromEuterpeprecatoria

    Article • Journal of Natural Products, December 2002, American Chemical Society (ACS)

    Professor Søren Brøgger Christensen

  93. Hydrophilic Carboxylic Acids and Iridoid Glycosides in the Juice of American and European Cranberries (Vaccinium macrocarpon and V. oxycoccos), Lingonberries (V. vitis-idaea), and Blueberries (V. myrtillus)

    Article • Journal of Agricultural and Food Chemistry, October 2002, American Chemical Society (ACS)

    karen a krogfelt, Professor Søren Brøgger Christensen

  94. Antiplasmodial Compounds fromCochlospermumtinctorium

    Article • Journal of Natural Products, September 2002, American Chemical Society (ACS)

    Professor Søren Brøgger Christensen

  95. Antiplasmodial Activity of Labdanes from Aframomum latifolium and Aframomum sceptrum

    Article • Planta Medica, July 2002, Thieme Publishing Group

    Professor Søren Brøgger Christensen

  96. Incorporation of the CrossFire Beilstein Database into the Organic Chemistry Curriculum at the Royal Danish School of Pharmacy

    Article • Journal of Chemical Education, June 2002, American Chemical Society (ACS)

    Professor Søren Brøgger Christensen

  97. In Vitro Antimycobacterial and Antilegionella Activity of Licochalcone A from Chinese Licorice Roots

    Article • Planta Medica, May 2002, Thieme Publishing Group

    Professor Søren Brøgger Christensen

  98. Design, Synthesis, and Pharmacological Evaluation of Thapsigargin Analogues for Targeting Apoptosis to Prostatic Cancer Cells

    Article • Journal of Medicinal Chemistry, December 2001, American Chemical Society (ACS)

    Professor Søren Brøgger Christensen

  99. Inhibition of Fumarate Reductase inLeishmania major and L. donovani by Chalcones

    Article • Antimicrobial Agents and Chemotherapy, July 2001, ASM Journals

    Professor Søren Brøgger Christensen

  100. Absolute Configuration and Antiprotozoal Activity of Minquartynoic Acid

    Article • Journal of Natural Products, September 2000, American Chemical Society (ACS)

    Professor Søren Brøgger Christensen

  101. A Simple and Efficient Separation of the Curcumins, the Antiprotozoal Constituents of Curcuma longa

    Article • Planta Medica, May 2000, Thieme Publishing Group

    Professor Søren Brøgger Christensen

  102. Thapsigargin analogues for targeting programmed death of androgen-Independent prostate cancer cells

    Article • Bioorganic & Medicinal Chemistry, July 1999, Elsevier

    Professor Søren Brøgger Christensen

  103. The antileishmanial activity of novel oxygenated chalcones and their mechanism of action

    Article • Journal of Antimicrobial Chemotherapy, June 1999, Oxford University Press (OUP)

    Professor Søren Brøgger Christensen

  104. ACTA, a fluorescent analogue of thapsigargin, is a potent inhibitor and a conformational probe of skeletal muscle Ca2+ -ATPase

    Article • FEBS Letters, November 1998, Wiley

    Professor Søren Brøgger Christensen

  105. Antileishmanial Chalcones:  Statistical Design, Synthesis, and Three-Dimensional Quantitative Structure−Activity Relationship Analysis

    Article • Journal of Medicinal Chemistry, November 1998, American Chemical Society (ACS)

    Professor Søren Brøgger Christensen

  106. limonoids from Khaya senegalensis

    Article • Phytochemistry, November 1998, Elsevier

    Professor Søren Brøgger Christensen

  107. Colouring agents in yellow and white flowered papaver radicatum in Northern Greenland

    Article • Biochemical Systematics and Ecology, October 1998, Elsevier

    Professor Søren Brøgger Christensen

  108. Modifications of the α,β-Double bond in chalcones only Marginally affect the antiprotozoal activities

    Article • Bioorganic & Medicinal Chemistry, July 1998, Elsevier

    Professor Søren Brøgger Christensen

  109. A tool coming of age: thapsigargin as an inhibitor of sarco-endoplasmic reticulum Ca2+-ATPases

    Article • Trends in Pharmacological Sciences, April 1998, Elsevier

    Professor Søren Brøgger Christensen

  110. The Novel Oxygenated Chalcone, 2,4‐Dimethoxy‐4'‐Butoxychalcone, Exhibits Potent Activity against Human Malaria ParasitePlasmodium falciparumIn Vitro and Rodent ParasitesPlasmodium bergheiandPlasmodium yoeliiIn Vivo

    Article • The Journal of Infectious Diseases, November 1997, Oxford University Press (OUP)

    Professor Søren Brøgger Christensen

  111. Antiprotozoal Compounds fromAsparagus africanus

    Article • Journal of Natural Products, October 1997, American Chemical Society (ACS)

    Professor Søren Brøgger Christensen

  112. New Anti-HIV-1, Antimalarial, and Antifungal Compounds fromTerminalia bellerica

    Article • Journal of Natural Products, July 1997, American Chemical Society (ACS)

    Professor Søren Brøgger Christensen

  113. Two New Antiprotozoal 5-Methylcoumarins fromVernonia brachycalyx

    Article • Journal of Natural Products, May 1997, American Chemical Society (ACS)

    Professor Søren Brøgger Christensen

  114. Lewis or brønsted acid provoked rearrangements in ortho-(1,1-dimethylpropenyl)phenols

    Article • Tetrahedron, April 1997, Elsevier

    Professor Søren Brøgger Christensen

  115. Discovery of oxygentade chalcones as novel antimalarial agents

    Article • Annals of Tropical Medicine and Parasitology, March 1997, Taylor & Francis

    Professor Søren Brøgger Christensen

  116. Synthesis, isolation and identification of glucuronides and mercapturic acids of a novel antiparasitic agent, licochalcone A

    Article • Xenobiotica, January 1997, Taylor & Francis

    Professor Søren Brøgger Christensen

  117. Isolation of an angiotensin converting enzyme (ACE) inhibitor from Olea europaea and Olea lancea

    Article • Phytomedicine, March 1996, Elsevier

    Professor Søren Brøgger Christensen

  118. Syntheses of 11-Hydroxylated Guaianolides.

    Article • Acta Chemica Scandinavica, January 1996, Danish Chemical Society

    Professor Søren Brøgger Christensen

  119. The antileishmanial agent licochalcone A interferes with the function of parasite mitochondria

    Article • Antimicrobial Agents and Chemotherapy, December 1995, ASM Journals

    Professor Søren Brøgger Christensen

  120. Synthesis of antiparasitic licorice chalcones

    Article • Bioorganic & Medicinal Chemistry Letters, March 1995, Elsevier

    Professor Søren Brøgger Christensen

  121. Structure-Activity Relationships of Analogs of Thapsigargin Modified at O-11 and O-12

    Article • Journal of Medicinal Chemistry, January 1995, American Chemical Society (ACS)

    Professor Søren Brøgger Christensen

  122. Thapsigargin, a novel molecular probe for studying intracellular calcium release and storage

    Article • Agents and Actions, December 1994, Springer Science + Business Media

    Professor Søren Brøgger Christensen

  123. Licochalcone A, a new antimalarial agent, inhibits in vitro growth of the human malaria parasite Plasmodium falciparum and protects mice from P. yoelii infection.

    Article • Antimicrobial Agents and Chemotherapy, July 1994, ASM Journals

    Professor Søren Brøgger Christensen

  124. Antileishmanial activity of licochalcone A in mice infected with Leishmania major and in hamsters infected with Leishmania donovani.

    Article • Antimicrobial Agents and Chemotherapy, June 1994, ASM Journals

    Professor Søren Brøgger Christensen

  125. Molluscicidal saponins from a zimbabwean strain of Phytolacca dodecandra

    Article • Phytochemistry, June 1994, Elsevier

    Professor Søren Brøgger Christensen

  126. Ca2+-ATPase inhibitory activity of a locked analogue of thapsigargin

    Article • Bioorganic & Medicinal Chemistry Letters, March 1994, Elsevier

    Professor Søren Brøgger Christensen

  127. Selective Transformations of the Ca2+ Pump Inhibitor Thapsigargin.

    Article • Acta Chemica Scandinavica, January 1994, Danish Chemical Society

    Professor Søren Brøgger Christensen

  128. Derivatives of thapsigargin as probes of its binding site on endoplasmic reticulum Ca2+ATPase

    Article • FEBS Letters, December 1993, Wiley

    Professor Søren Brøgger Christensen

  129. Licochalcone A, a novel antiparasitic agent with potent activity against human pathogenic protozoan species of Leishmania.

    Article • Antimicrobial Agents and Chemotherapy, December 1993, ASM Journals

    Professor Søren Brøgger Christensen

  130. Localization of the Acyl Groups in Proazulene Guaianolides from Thapsia transtagana and Thapsia garganica

    Article • Journal of Natural Products, March 1993, American Chemical Society (ACS)

    Professor Søren Brøgger Christensen

  131. Molluscicidal saponins from Phytolacca dodecandra

    Article • Phytochemistry, March 1993, Elsevier

    Professor Søren Brøgger Christensen

  132. Calcium entry in Xenopus oocytes: effects of inositol trisphosphate, thapsigargin and DMSO

    Article • Cell Calcium, February 1993, Elsevier

    Professor Søren Brøgger Christensen

  133. The Molluscicidal Activity of Coumarins from Ethulia conyzoides and of Dicumarol

    Article • Planta Medica, August 1992, Thieme Publishing Group

    Professor Søren Brøgger Christensen

  134. Toxicodynamics of tumour promoters of mouse skin III. Specific binding of the tumour promoter thapsigargin as measured by the cold-acetone filter assay

    Article • Journal of Cancer Research and Clinical Oncology, May 1992, Springer Science + Business Media

    Professor Søren Brøgger Christensen

  135. Comparison of the Effects of Thapsigargin and BAY K 8644 on Spontaneous Mechanical Activity in Rat Portal Vein and Contractile Responses of Rat Cardiac Muscle

    Article • Pharmacology & Toxicology, February 1992, Wiley

    Professor Søren Brøgger Christensen

  136. The Absolute and Relative Configuration of the Molluscicides Ethuliacoumarin A and Isoethuliacoumarin A.

    Article • Acta Chemica Scandinavica, January 1992, Danish Chemical Society

    Professor Søren Brøgger Christensen

  137. Thapsigargin-Induced Increase in Cytoplasmic Ca2+Concentration and Aldosterone Production in Rat Adrenal Glomerulosa Cells: Interaction with Potassium and Angiotensin-II

    Article • Endocrinology, May 1991, Endocrine Society

    Professor Søren Brøgger Christensen

  138. Guaiane esters from Thapsia villosa

    Article • Phytochemistry, January 1991, Elsevier

    Professor Søren Brøgger Christensen

  139. Exciton Coupling in Circular Dichroic Spectroscopy as a Tool for Establishing the Absolute Configuration of alpha,beta-Unsaturated Esters of Allylic Alcohols.

    Article • Acta Chemica Scandinavica, January 1991, Danish Chemical Society

    Professor Søren Brøgger Christensen

  140. New Proazulene Guaianolides from Thapsia villosa

    Article • Journal of Natural Products, November 1990, American Chemical Society (ACS)

    Professor Søren Brøgger Christensen

  141. Ca2+ influx in human T lymphocytes is induced independently of inositol phosphate production by mobilization of intracellular Ca2+ stores. A study with the Ca2+ endoplasmic reticulum-ATPase inhibitor thapsigargin

    Article • European Journal of Immunology, October 1990, Wiley

    Professor Søren Brøgger Christensen

  142. Inositol trisphosphate and thapsigargin discriminate endoplasmic reticulum stores of calcium in rat brain

    Article • Biochemical and Biophysical Research Communications, October 1990, Elsevier

    Professor Søren Brøgger Christensen

  143. Hydroindene sesquiterpenes from Thapsia villosa

    Article • Phytochemistry, January 1990, Elsevier

    Professor Søren Brøgger Christensen

  144. Thapsigargin, a novel molecular probe for studying intracellular calcium release and storage

    Article • Agents and Actions, April 1989, Springer Science + Business Media

    Professor Søren Brøgger Christensen

  145. Effect of thapsigargin on cytoplasmic Ca2+ and proliferation of human lymphocytes in relation to AIDS

    Article • Biochimica et Biophysica Acta (BBA) - Bioenergetics, December 1988, Elsevier

    Professor Søren Brøgger Christensen

  146. Effect of thapsigargin on cytoplasmic Ca2+ and proliferation of human lymphocytes in relations to AIDS

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, December 1988, Elsevier

    Professor Søren Brøgger Christensen

  147. Analysis of the stimulative effect of thapsigargin, a non-TPA-type tumour promoter, on arachidonic acid metabolism in rat peritoneal macrophages

    Article • British Journal of Pharmacology, July 1988, Wiley

    Professor Søren Brøgger Christensen

  148. Dimethyl sulfoxide decreases the fluorescence yield of the reaction between histamine and ortho-phthalaldehyde and may influence histamine release

    Article • Agents and Actions, June 1988, Springer Science + Business Media

    Professor Søren Brøgger Christensen

  149. Interpretation of the NMR and Circular Dichroic Data of the Sesquiterpene Lactone Thapsigargin.

    Article • Acta Chemica Scandinavica, January 1988, Danish Chemical Society

    Professor Søren Brøgger Christensen

  150. Effects of Thapsigargin in Isolated Rat Thoracic Aorta

    Article • Pharmacology & Toxicology, January 1988, Wiley

    Professor Søren Brøgger Christensen

  151. A New Sesquiterpene from Laserpitium latifolium

    Article • Journal of Natural Products, September 1987, American Chemical Society (ACS)

    Professor Søren Brøgger Christensen

  152. Stimulation of arachidonic acid metabolism in rat peritoneal macrophages by thapsigargin, a non-(12-O-tetradecanoylphorbol-13-acetate) (TPA)-type tumor promoter

    Article • Journal of Cancer Research and Clinical Oncology, June 1987, Springer Science + Business Media

    Professor Søren Brøgger Christensen

  153. The inflammatory and tumor-promoting sesquiterpene lactone, thapsigargin, activates platelets by selective mobilization of calcium as shown by protein phosphorylations

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, January 1987, Elsevier

    Professor Søren Brøgger Christensen

  154. Natural Products and Drug Development, Alfred Benzon Symposium 20Edited by P. Krogsgaard-Larsen, S. Brogger Christensen, and Helmer Kofod

    Article • The Journal of Clinical Pharmacology, January 1987, Wiley

    Professor Søren Brøgger Christensen

  155. Isorhamnetin3-(2,6-dirhamnosylgalactoside)-7-rhamnoside and 3-(6-rhamnosylgalactoside)-7-rhamnoside from Rhazya stricta

    Article • Phytochemistry, December 1986, Elsevier

    Professor Søren Brøgger Christensen

  156. Synergistic stimulation of histamine release from rat peritoneal mast cells by 12-O-tetradecanoylphorbol 13-acetate (TPA)-type and non-TPA-type tumor promoters

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, June 1986, Elsevier

    Professor Søren Brøgger Christensen

  157. Thapsigargin, a histamine secretagogue, is a non-12-O-tetradecanolphorbol-13-acetate (TPA) type tumor promoter in two-stage mouse skin carcinogenesis

    Article • Journal of Cancer Research and Clinical Oncology, June 1986, Springer Science + Business Media

    Professor Søren Brøgger Christensen

  158. Structure of a Pro-1,4-dimethylazulene Guaianolide from Thapsia garganica L.

    Article • Acta Chemica Scandinavica, January 1986, Danish Chemical Society

    Professor Søren Brøgger Christensen

  159. Natural Products and Drug Development

    Article • Journal of Pharmaceutical Sciences, August 1985, Elsevier

    Professor Søren Brøgger Christensen

  160. The ability of thapsigargin and thapsigargicin to activate cells involved in the inflammatory response

    Article • British Journal of Pharmacology, July 1985, Wiley

    Professor Søren Brøgger Christensen

  161. Analogues of the Histamine Liberating Dihydroxysesquiterpene Lactone Thapsigargin. Synthesis, X-Ray Analysis and Chemistry.

    Article • Acta Chemica Scandinavica, January 1985, Danish Chemical Society

    Professor Søren Brøgger Christensen

  162. Atriplex nummularia, a Source for the Two Molluscicide Saponins: Hederagenin-3-O-β-D-Glucuronopyranoside and Calenduloside E

    Article • Journal of Natural Products, January 1985, American Chemical Society (ACS)

    Professor Søren Brøgger Christensen

  163. Absolute configurations of the histamine liberating sesquiterpene lactones thapsigargin and trilobolide

    Article • Tetrahedron Letters, January 1985, Elsevier

    Professor Søren Brøgger Christensen

  164. Structure of histamine releasing guaianolides from Thapsia species

    Article • Phytochemistry, January 1984, Elsevier

    Professor Søren Brøgger Christensen

  165. Determination of cyanogenic compounds by thin-layer chromatography. 1. A densitometric method for quantification of cyanogenic glycosides, employing enzyme preparations (.beta.-glucuronidase) from Helix pomatia and picrate-impregnated ion-exchange sheets

    Article • Journal of Agricultural and Food Chemistry, July 1983, American Chemical Society (ACS)

    Professor Søren Brøgger Christensen

  166. Stereochemistry and carbon-13 nuclear magnetic resonance of the histamineliberating sesquiterpene lactone thapsigargin. A modification of Horeau's method

    Article • The Journal of Organic Chemistry, February 1983, American Chemical Society (ACS)

    Professor Søren Brøgger Christensen

  167. Thapsigargin and thapsigargicin, two histamine liberating sesquiterpene lactones from Thapsia garganica. X-ray analysis of the 7,11-epoxide of thapsigargin

    Article • The Journal of Organic Chemistry, February 1982, American Chemical Society (ACS)

    Professor Søren Brøgger Christensen

  168. 2-β-d-Glucopyranosyloxy-2-methylpropanol in Acacia sieberana var. woodii

    Article • Phytochemistry, January 1982, Elsevier

    Professor Søren Brøgger Christensen

  169. 1-β-vicianosyl-(S)-2-methylbutyrate, a 1-O-acylglycoside from Acacia sieberana var. Woodii

    Article • Phytochemistry, January 1982, Elsevier

    Professor Søren Brøgger Christensen

  170. Proacaciberin, A cyanogenic glycoside from Acacia sieberiana var. Woodii

    Article • Phytochemistry, January 1981, Elsevier

    Professor Søren Brøgger Christensen

  171. Structural elucidation and partial synthesis of 3-hydroxyheterodendrin, a cyanogenic glucoside from Acacia sieberiana var. woodii

    Article • Phytochemistry, January 1981, Elsevier

    Professor Søren Brøgger Christensen

  172. Preparations of deuterium labelled guvacine and isoguvacine

    Article • Journal of Labelled Compounds and Radiopharmaceuticals, March 1980, Wiley

    Professor Søren Brøgger Christensen

  173. Thapsigargin, constitution of a sesquiterpene lactone histamine liberator from thapsia garganica

    Article • Tetrahedron Letters, January 1980, Elsevier

    Professor Søren Brøgger Christensen

  174. Muscimol Analogues. I. Syntheses of 4- and 8-Aminocyclohepteno[1,2-d]isoxazol-3-ols and 4-(3-Aminopropyl)-5-methyl-3-isoxazolol.

    Article • Acta Chemica Scandinavica, January 1977, Danish Chemical Society

    Professor Søren Brøgger Christensen

  175. Structural Analogues of GABA. A New Convenient Synthesis of Muscimol.

    Article • Acta Chemica Scandinavica, January 1976, Danish Chemical Society

    Professor Søren Brøgger Christensen

  176. Organic Hydroxylamine Derivatives. XIII. The Configurations of a Series of Stereoisomeric 3-Methoxy-5-acylisoxazole Ketoximes.

    Article • Acta Chemica Scandinavica, January 1975, Danish Chemical Society

    Professor Søren Brøgger Christensen

  177. Organic Hydroxylamine Derivatives. XII. Structural Analogues of gamma-Aminobutyric Acid (GABA) of the Isoxazole Enol-betaine Type. Synthesis of Some 3-Hydroxy-5-(1-aminoalkyl)isoxazole Zwitterions.

    Article • Acta Chemica Scandinavica, January 1974, Danish Chemical Society

    Professor Søren Brøgger Christensen

  178. Organic Hydroxylamine Derivatives. VIII. Structural Analogues of GABA of the Isoxazole Enol-Betaine Type. Synthesis of 5,6,7,8-Tetrahydro-4H-isoxazolo[3,4-d]azepin-3-ol Zwitterion and Some Derivatives.

    Article • Acta Chemica Scandinavica, January 1973, Danish Chemical Society

    Professor Søren Brøgger Christensen

  179. Conformational Analysis. VIII. Separation and PMR Spectra of Some 4-Oxo-1,3-dioxans Derived from Diastereoisomeric 3-Hydroxy-2-methylbutyric Acids.

    Article • Acta Chemica Scandinavica, January 1973, Danish Chemical Society

    Professor Søren Brøgger Christensen

  180. Organic Hydroxylamine Derivatives. VII. Isoxazolin-5-ones. An Investigation of a Reaction Sequence Previously Stated to Give 3-Hydroxyisoxazoles.

    Article • Acta Chemica Scandinavica, January 1973, Danish Chemical Society

    Professor Søren Brøgger Christensen