All Stories

  1. Cysteine synthases CYSL-1 and CYSL-2 mediate C. elegans heritable adaptation to P. vranovensis infection

    Article • Nature Communications, April 2020, Springer Science + Business Media

    Dr Albert Koulman

  2. A Combination of Metabolites Predicts Adherence to the Mediterranean Diet Pattern and Its Associations with Insulin Sensitivity and Lipid Homeostasis in the General Population: The Fenland Study, United Kingdom

    Article • Journal of Nutrition, October 2019, Oxford University Press (OUP)

    Dr Albert Koulman

  3. Evidence from 3-month-old infants shows that a combination of postnatal feeding and exposures in utero shape lipid metabolism

    Article • Scientific Reports, October 2019, Springer Science + Business Media

    Dr Albert Koulman

  4. Relationship between the lipid composition of maternal plasma and infant plasma through breast milk

    Article • Metabolomics, September 2019, Springer Science + Business Media

    Dr Albert Koulman

  5. Fermentation of Milk into Yoghurt and Cheese Leads to Contrasting Lipid and Glyceride Profiles

    Article • Nutrients, September 2019, MDPI AG

    Dr Albert Koulman

  6. Compartmentalized Synthesis of Triacylglycerol at the Inner Nuclear Membrane Regulates Nuclear Organization

    Article • Developmental Cell, September 2019, Elsevier

    Dr Albert Koulman

  7. Accelerated phosphatidylcholine turnover in macrophages promotes adipose tissue inflammation in obesity

    Article • eLife, August 2019, eLife

    Dr Albert Koulman

  8. Rapid profiling of triglycerides in human breast milk using liquid extraction surface analysis Fourier transform mass spectrometry reveals new very long chain fatty acids and differences within individuals

    Article • Rapid Communications in Mass Spectrometry, July 2019, Wiley

    Dr Albert Koulman

  9. The Lipid and Glyceride Profiles of Infant Formula Differ by Manufacturer, Region and Date Sold

    Article • Nutrients, May 2019, MDPI AG

    Dr Albert Koulman

  10. Human Milk Short-Chain Fatty Acid Composition is Associated with Adiposity Outcomes in Infants

    Article • Journal of Nutrition, May 2019, Oxford University Press (OUP)

    Dr Albert Koulman

  11. Changes in plasma phospholipid fatty acid profiles over 13 years and correlates of change: European Prospective Investigation into Cancer and Nutrition-Norfolk Study

    Article • American Journal of Clinical Nutrition, April 2019, Oxford University Press (OUP)

    Dr Albert Koulman

  12. Associations of circulating very-long-chain saturated fatty acids and incident type 2 diabetes: a pooled analysis of prospective cohort studies

    Article • American Journal of Clinical Nutrition, April 2019, Oxford University Press (OUP)

    Dr Albert Koulman, Dr Jason Wu

  13. An Unbiased Lipid Phenotyping Approach To Study the Genetic Determinants of Lipids and Their Association with Coronary Heart Disease Risk Factors

    Article • Journal of Proteome Research, March 2019, American Chemical Society (ACS)

    Dr Albert Koulman

  14. Assessing the causal association of glycine with risk of cardio-metabolic diseases

    Article • Nature Communications, March 2019, Springer Science + Business Media

    Dr Albert Koulman

  15. Metabolomic and lipidomic plasma profile changes in human participants ascending to Everest Base Camp

    Article • Scientific Reports, February 2019, Springer Science + Business Media

    Dr Albert Koulman, Hugh Montgomery

  16. Mobilising vitamin D from adipose tissue: The potential impact of exercise

    Article • Nutrition Bulletin, February 2019, Wiley

    Dr Albert Koulman

  17. Altered triglyceride and phospholipid metabolism predates the diagnosis of gestational diabetes in obese pregnancy

    Article • Molecular Omics, January 2019, Royal Society of Chemistry

    Dr Albert Koulman

  18. Sphingolipid dysregulation due to lack of functional KDSR impairs proplatelet formation causing thrombocytopenia

    Article • Haematologica, November 2018, Ferrata Storti Foundation (Haematologica)

    Dr Albert Koulman

  19. The Dietary Total-Fat Content Affects the In Vivo Circulating C15:0 and C17:0 Fatty Acid Levels Independently

    Article • Nutrients, November 2018, MDPI AG

    Dr Albert Koulman

  20. Fatty acid biomarkers of dairy fat consumption and incidence of type 2 diabetes: A pooled analysis of prospective cohort studies

    Article • PLoS Medicine, October 2018, PLOS

    Dr Albert Koulman, Dr Jason Wu

  21. The Dietary Total-Fat Content Affects the In Vivo Circulating C15:0 and C17:0 Fatty Acid Concentrations Independently to the Dietary Fatty Acid Compositions; Highlighting Dietary Routes that may Attenuate the Development of Metabolic Disease

    Article • September 2018, MDPI AG

    Dr Albert Koulman

  22. Associations between the maternal circulating lipid profile in pregnancy and fetal imprinted gene alleles: a cohort study

    Article • Reproductive Biology and Endocrinology, August 2018, Springer Science + Business Media

    Dr Albert Koulman

  23. The validation of biomarkers of metabolic efficacy in infant nutrition

    Article • Nutrition Bulletin, August 2018, Wiley

    Dr Albert Koulman

  24. Peroxisome Proliferator-Activated Receptor γ2 Controls the Rate of Adipose Tissue Lipid Storage and Determines Metabolic Flexibility

    Article • Cell Reports, August 2018, Elsevier

    Dr Albert Koulman

  25. Placental polyamine metabolism differs by fetal sex, fetal growth restriction, and preeclampsia

    Article • JCI Insight, July 2018, American Society for Clinical Investigation

    Dr Albert Koulman, Dr Ulla Sovio

  26. Hepatic steatosis risk is partly driven by increased de novo lipogenesis following carbohydrate consumption

    Article • June 2018, Springer Science + Business Media

    Dr Albert Koulman

  27. PCYT1A Regulates Phosphatidylcholine Homeostasis from the Inner Nuclear Membrane in Response to Membrane Stored Curvature Elastic Stress

    Article • Developmental Cell, May 2018, Elsevier

    Dr Albert Koulman

  28. Risk thresholds for alcohol consumption: combined analysis of individual-participant data for 599 912 current drinkers in 83 prospective studies

    Article • The Lancet, April 2018, Elsevier

    Dr Albert Koulman

  29. Metabolomics and Lipidomics Study of Mouse Models of Type 1 Diabetes Highlights Divergent Metabolism in Purine and Tryptophan Metabolism Prior to Disease Onset

    Article • Journal of Proteome Research, February 2018, American Chemical Society (ACS)

    Dr Albert Koulman

  30. Compositional marker in vivo reveals intramyocellular lipid turnover during fasting-induced lipolysis

    Article • Scientific Reports, February 2018, Nature

    Dr Albert Koulman

  31. Association between plasma phospholipid saturated fatty acids and metabolic markers of lipid, hepatic, inflammation and glycaemic pathways in eight European countries: a cross-sectional analysis in the EPIC-InterAct study

    Article • BMC Medicine, November 2017, Springer Science + Business Media

    Dr Albert Koulman

  32. Peroxisomal 2-Hydroxyacyl-CoA Lyase Is Involved in Endogenous Biosynthesis of Heptadecanoic Acid

    Article • Molecules, October 2017, MDPI AG

    Dr Albert Koulman

  33. A combination of plasma phospholipid fatty acids and its association with incidence of type 2 diabetes: The EPIC-InterAct case-cohort study

    Article • PLoS Medicine, October 2017, PLOS

    Dr Albert Koulman

  34. massPix: an R package for annotation and interpretation of mass spectrometry imaging data for lipidomics

    Article • Metabolomics, September 2017, Springer Science + Business Media

    Dr Albert Koulman

  35. Lipidomic profiling of human adipose tissue identifies a pattern of lipids associated with fish oil supplementation

    Article • Journal of Proteome Research, June 2017, American Chemical Society (ACS)

    Dr Albert Koulman

  36. Plasma phospholipid fatty acid profile confirms compliance to a novel saturated fat-reduced, monounsaturated fat-enriched dairy product intervention in adults at moderate cardiovascular risk: a randomized controlled trial

    Article • Nutrition Journal, May 2017, Springer Science + Business Media

    Dr Albert Koulman

  37. Odd Chain Fatty Acids; New Insights of the Relationship Between the Gut Microbiota, Dietary Intake, Biosynthesis and Glucose Intolerance

    Article • Scientific Reports, March 2017, Nature

    Dr Albert Koulman

  38. Lipid zonation and phospholipid remodeling in nonalcoholic fatty liver disease

    Article • Hepatology, February 2017, Wiley

    Dr susan e Davies, Michael Allison, Dr Albert Koulman

  39. The translation of lipid profiles to nutritional biomarkers in the study of infant metabolism

    Article • Metabolomics, January 2017, Springer Science + Business Media

    Dr Albert Koulman

  40. Interlaboratory Reproducibility of a Targeted Metabolomics Platform for Analysis of Human Serum and Plasma

    Article • Analytical Chemistry, January 2017, American Chemical Society (ACS)

    Dr Albert Koulman

  41. Computational tools and workflows in metabolomics: An international survey highlights the opportunity for harmonisation through Galaxy

    Article • Metabolomics, December 2016, Springer Science + Business Media

    Dr Albert Koulman, Prof. Markus Ralser

  42. Genetic Predisposition to an Impaired Metabolism of the Branched-Chain Amino Acids and Risk of Type 2 Diabetes: A Mendelian Randomisation Analysis

    Article • PLoS Medicine, November 2016, PLOS

    Dr Albert Koulman

  43. UPLC-MS/MS Determination of Deuterated 25-Hydroxyvitamin D (d3-25OHD3) and Other Vitamin D Metabolites for the Measurement of 25OHD Half-Life

    Article • November 2016, Springer Science + Business Media

    Dr Albert Koulman

  44. An Unbiased Lipidomics Approach Identifies Early Second Trimester Lipids Predictive of Maternal Glycemic Traits and Gestational Diabetes Mellitus

    Article • Diabetes Care, October 2016, American Diabetes Association

    Dr Albert Koulman

  45. Association of Plasma Phospholipid n-3 and n-6 Polyunsaturated Fatty Acids with Type 2 Diabetes: The EPIC-InterAct Case-Cohort Study

    Article • PLoS Medicine, July 2016, PLOS

    Dr Albert Koulman

  46. Myc Expression Drives Aberrant Lipid Metabolism in Lung Cancer

    Article • Cancer Research, June 2016, American Association for Cancer Research (AACR)

    Dr Albert Koulman

  47. A novel family of cyclic oligopeptides derived from ribosomal peptide synthesis of an in planta-induced gene, gigA, in Epichloë endophytes of grasses

    Article • Fungal Genetics and Biology, December 2015, Elsevier

    Dr Albert Koulman

  48. Data standards can boost metabolomics research, and if there is a will, there is a way

    Article • Metabolomics, November 2015, Springer Science + Business Media

    Dr Albert Koulman

  49. Hyphenating size‐exclusion chromatography with electrospray mass spectrometry; using on‐line liquid‐liquid extraction to study the lipid composition of lipoprotein particles

    Article • Rapid Communications in Mass Spectrometry, October 2015, Wiley

    Dr Albert Koulman

  50. A QTL analysis of host plant effects on fungal endophyte biomass and alkaloid expression in perennial ryegrass

    Article • Molecular Breeding, July 2015, Springer Science + Business Media

    Dr Albert Koulman

  51. Mechanistic insights revealed by lipid profiling in monogenic insulin resistance syndromes

    Article • Genome Medicine, June 2015, Springer Science + Business Media

    Dr Albert Koulman

  52. Lipidomic Analyses, Breast- and Formula-Feeding, and Growth in Infants

    Article • The Journal of Pediatrics, February 2015, Elsevier

    Dr Albert Koulman

  53. A Review of Odd-Chain Fatty Acid Metabolism and the Role of Pentadecanoic Acid (C15:0) and Heptadecanoic Acid (C17:0) in Health and Disease

    Article • Molecules, January 2015, MDPI AG

    Dr Albert Koulman

  54. Differences in the prospective association between individual plasma phospholipid saturated fatty acids and incident type 2 diabetes: the EPIC-InterAct case-cohort study

    Article • The Lancet Diabetes & Endocrinology, October 2014, Elsevier

    Dr Albert Koulman, Francesca Crowe

  55. The development and validation of a fast and robust dried blood spot based lipid profiling method to study infant metabolism

    Article • Metabolomics, February 2014, Springer Science + Business Media

    Dr Albert Koulman

  56. Towards metabolic biomarkers of insulin resistance and type 2 diabetes: progress from the metabolome

    Article • The Lancet Diabetes & Endocrinology, January 2014, Elsevier

    Dr Albert Koulman

  57. Omega-3 PUFA supplementation and the response to evoked endotoxemia in healthy volunteers

    Article • Molecular Nutrition & Food Research, November 2013, Wiley

    Dr Albert Koulman

  58. Deletion and Gene Expression Analyses Define the Paxilline Biosynthetic Gene Cluster in Penicillium paxilli

    Article • Toxins, August 2013, MDPI AG

    Dr Albert Koulman

  59. An Extracellular Siderophore Is Required to Maintain the Mutualistic Interaction of Epichloë festucae with Lolium perenne

    Article • PLoS Pathogens, May 2013, PLOS

    Dr Albert Koulman

  60. Development and validation of a robust automated analysis of plasma phospholipid fatty acids for metabolic phenotyping of large epidemiological studies

    Article • Genome Medicine, January 2013, Springer Science + Business Media

    Dr Albert Koulman

  61. Identification of extracellular siderophores and a related peptide from the endophytic fungus Epichloë festucae in culture and endophyte-infected Lolium perenne

    Article • Phytochemistry, March 2012, Elsevier

    Dr Albert Koulman, Shaun Lott

  62. Design and cohort description of the InterAct Project: an examination of the interaction of genetic and lifestyle factors on the incidence of type 2 diabetes in the EPIC Study

    Article • Diabetologia, June 2011, Springer Science + Business Media

    Dr Albert Koulman, Francesca Crowe

  63. Reduced Coniferin and Enhanced 6-Methoxypodophyllotoxin Production in Linum flavum Cell Cultures

    Article • Pharmacognosy Journal, December 2010, EManuscript Services

    Dr Albert Koulman

  64. Comprehensive Lipidomics Analysis of Bioactive Lipids in Complex Regulatory Networks

    Article • Analytical Chemistry, September 2010, American Chemical Society (ACS)

    Dietrich Volmer, Dr Albert Koulman

  65. Quantitative determination of vitamin D metabolites in plasma using UHPLC-MS/MS

    Article • Analytical and Bioanalytical Chemistry, July 2010, Springer Science + Business Media

    Dietrich Volmer, Dr Albert Koulman

  66. Structure of a Eukaryotic Nonribosomal Peptide Synthetase Adenylation Domain That Activates a Large Hydroxamate Amino Acid in Siderophore Biosynthesis

    Article • Journal of Biological Chemistry, November 2009, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Albert Koulman, Shaun Lott

  67. Identification of Two Aflatrem Biosynthesis Gene Loci in Aspergillus flavus and Metabolic Engineering of Penicillium paxilli To Elucidate Their Function

    Article • Applied and Environmental Microbiology, October 2009, ASM Journals

    Dr Albert Koulman

  68. Comparative High-Speed Profiling of Carboxylic Acid Metabolite Levels by Differential Isotope-Coded MALDI Mass Spectrometry

    Article • Analytical Chemistry, August 2009, American Chemical Society (ACS)

    Dietrich Volmer, Dr Albert Koulman

  69. Semi-quantitative and structural metabolic phenotyping by direct infusion ion trap mass spectrometry and its application in genetical metabolomics

    Article • Rapid Communications in Mass Spectrometry, June 2009, Wiley

    Dr Albert Koulman

  70. High‐resolution extracted ion chromatography, a new tool for metabolomics and lipidomics using a second‐generation orbitrap mass spectrometer

    Article • Rapid Communications in Mass Spectrometry, April 2009, Wiley

    Dietrich Volmer, Dr Albert Koulman

  71. From differentiating metabolites to biomarkers

    Article • Analytical and Bioanalytical Chemistry, March 2009, Springer Science + Business Media

    Dietrich Volmer, Dr Albert Koulman

  72. Perspectives for metabolomics in human nutrition: an overview

    Article • Nutrition Bulletin, November 2008, Wiley

    Dietrich Volmer, Dr Albert Koulman

  73. Bioconversion of deoxypodophyllotoxin into epipodophyllotoxin in E. coli using human cytochrome P450 3A4

    Article • Planta Medica, July 2008, Thieme Publishing Group

    Dr Albert Koulman

  74. E/Z-Thesinine-O-4′-α-rhamnoside, pyrrolizidine conjugates produced by grasses (Poaceae)

    Article • Phytochemistry, June 2008, Elsevier

    Dr Albert Koulman

  75. Advanced Data-Mining Strategies for the Analysis of Direct-Infusion Ion Trap Mass Spectrometry Data from the Association of Perennial Ryegrass with Its Endophytic Fungus, Neotyphodium lolii

    Article • PLANT PHYSIOLOGY, April 2008, American Society of Plant Biologists (ASPB)

    Dr Albert Koulman

  76. Defining Paxilline Biosynthesis inPenicillium paxilli

    Article • Journal of Biological Chemistry, April 2007, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Albert Koulman

  77. Peramine and other fungal alkaloids are exuded in the guttation fluid of endophyte-infected grasses

    Article • Phytochemistry, February 2007, Elsevier

    Dr Albert Koulman

  78. HPLC-photodiode array detection analysis of curcuminoids inCurcuma species indigenous to Indonesia

    Article • Phytochemical Analysis, January 2007, Wiley

    Dr Albert Koulman

  79. High-throughput direct-infusion ion trap mass spectrometry: a new method for metabolomics

    Article • Rapid Communications in Mass Spectrometry, January 2007, Wiley

    Dr Albert Koulman

  80. Analytical methods from the perspective of method standardization

    Article • January 2007, Springer Science + Business Media

    Dr Albert Koulman

  81. The Seasonal Variations of Lignan Profiles in Anthriscus sylvestris (L.) Hoffm

    Article • Planta Medica, January 2007, Thieme Publishing Group

    Dr Albert Koulman

  82. Combinatorial biosynthesis of medicinal plant secondary metabolites

    Article • Biomolecular Engineering, December 2006, Elsevier

    Dr Albert Koulman

  83. Bioconversion of deoxypodophyllotoxin into epipodophyllotoxin in E. coli using human cytochrome P450 3A4

    Article • Journal of Biotechnology, November 2006, Elsevier

    Dr Albert Koulman

  84. Four gene products are required for the fungal synthesis of the indole-diterpene, paspaline

    Article • FEBS Letters, February 2006, Wiley

    Dr Albert Koulman

  85. Lignans from Cell Suspension Cultures ofPhyllanthusniruri, an Indonesian Medicinal Plant

    Article • Journal of Natural Products, January 2006, American Chemical Society (ACS)

    Dr Albert Koulman

  86. Volatile components of the aerial parts ofArtemisia pontica L. grown in Bulgaria

    Article • Flavour and Fragrance Journal, January 2005, Wiley

    Dr Albert Koulman

  87. Aryltetralin Lignans from Linum mucronatum Bertol. ssp. mucronatum

    Article • Chemistry of Natural Compounds, January 2005, Springer Science + Business Media

    Dr Albert Koulman

  88. Chemical characterisation of three haemolytic compounds from the microalgal species Fibrocapsa japonica (Raphidophyceae)

    Article • Toxicon, March 2004, Elsevier

    Dr Albert Koulman

  89. Lignan profile of Linum meletonis

    Article • Biochemical Systematics and Ecology, January 2004, Elsevier

    Dr Albert Koulman

  90. Lignan Profiles of Indoor-Cultivated Anthriscus sylvestris

    Article • Planta Medica, October 2003, Thieme Publishing Group

    Dr Albert Koulman

  91. The Bioconversion Process of Deoxypodophyllotoxin with Linum flavum Cell Cultures

    Article • Planta Medica, August 2003, Thieme Publishing Group

    Dr Albert Koulman

  92. A Phytochemical Study of Lignans in Whole Plants and Cell Suspension Cultures of Anthriscus sylvestris

    Article • Planta Medica, August 2003, Thieme Publishing Group

    Dr Albert Koulman

  93. Realizing the promises of marine biotechnology

    Article • Biomolecular Engineering, July 2003, Elsevier

    Dr Albert Koulman

  94. Volatile components from Anthriscus sylvestris (L.) Hoffm.

    Article • Journal of Chromatography A, August 2002, Elsevier

    Dr Albert Koulman

  95. A Fast and Simple GC MS Method for Lignan Profiling in Anthriscus sylvestris and Biosynthetically Related Plant Species

    Article • Planta Medica, December 2001, Thieme Publishing Group

    Dr Albert Koulman

  96. The pharmaceutical exploration of cold water ascidians from the Netherlands: a possible source of new cytotoxic natural products

    Article • Journal of Biotechnology, April 1999, Elsevier

    Dr Albert Koulman

  97. Cytotoxicity of Natural Ginseng Glycosides and Semisynthetic Analogues

    Article • Planta Medica, February 1999, Thieme Publishing Group

    Dr Albert Koulman

  98. The pharmaceutical exploration of cold water ascidians from the Netherlands: a possible source of new cytotoxic natural products

    Article • January 1999, Elsevier

    Dr Albert Koulman

  99. Cytoxicity and Mode of Action of Aeroplysinin-1 and a Related Dienone from the SpongeAplysina aerophoba

    Article • Journal of Natural Products, January 1996, American Chemical Society (ACS)

    Dr Albert Koulman