All Stories

  1. On the track of the lipid transport pathway of the phospholipid flippase ATP8A2 - Mutation analysis of residues of the transmembrane segments M1, M2, M3 and M4

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, January 2024, Elsevier

    Dr Francesco Tadini Buoninsegni

  2. A bioelectrochemical approach based on a solid supported membrane to evaluate the effect of natural products on Ca2+-ATPase: The case of 6-gingerol

    Article • Electrochimica Acta, August 2023, Elsevier

    Dr Francesco Tadini Buoninsegni

  3. Electrogenic reaction step and phospholipid translocation pathway of the mammalian P4‐ATPase ATP8A2

    Article • FEBS Letters, August 2022, Wiley

    Dr Francesco Tadini Buoninsegni

  4. Stimulation of Ca 2+ ‐ATPase Transport Activity by a Small‐Molecule Drug

    Article • ChemMedChem, August 2021, Wiley

    Dr Francesco Tadini Buoninsegni

  5. Protein Adsorption on Solid Supported Membranes: Monitoring the Transport Activity of P-Type ATPases

    Article • Molecules, September 2020, MDPI AG

    Dr Francesco Tadini Buoninsegni

  6. Label-Free Bioelectrochemical Methods for Evaluation of Anticancer Drug Effects at a Molecular Level

    Article • Sensors, March 2020, MDPI AG

    Dr Francesco Tadini Buoninsegni

  7. Niosomal Formulation of a Lipoyl-Carnosine Derivative Targeting TRPA1 Channels in Brain

    Article • Pharmaceutics, December 2019, MDPI AG

    Dr Francesco Tadini Buoninsegni

  8. Superparamagnetic iron oxide nanoparticles (SPIONs) modulate hERG ion channel activity

    Article • Nanotoxicology, August 2019, Taylor & Francis

    Dr Francesco Tadini Buoninsegni, Roberta Gualdani

  9. Phosphatidylserine flipping by the P4-ATPase ATP8A2 is electrogenic

    Article • Proceedings of the National Academy of Sciences, August 2019, Proceedings of the National Academy of Sciences

    Dr Francesco Tadini Buoninsegni

  10. A Comparative Study of Phosphatidylcholine versus Phosphatidylserine-Based Solid Supported Membranes for the Preparation of Liposome-Rich Interfaces

    Article • Langmuir, September 2018, American Chemical Society (ACS)

    Dr Francesco Tadini Buoninsegni

  11. Drug Interactions With the Ca2+-ATPase From Sarco(Endo)Plasmic Reticulum (SERCA)

    Article • Frontiers in Molecular Biosciences, April 2018, Frontiers

    Dr Francesco Tadini Buoninsegni

  12. Selectivity of the phospholamban ion channel investigated by single channel measurements

    Article • Journal of Electroanalytical Chemistry, March 2018, Elsevier

    Dr Francesco Tadini Buoninsegni

  13. Monitoring Interactions Inside Cells by Advanced Spectroscopies: Overview of Copper Transporters and Cisplatin

    Article • Current Medicinal Chemistry, February 2018, Bentham Science Publishers

    Dr Francesco Tadini Buoninsegni

  14. Molecular Insights into hERG Potassium Channel Blockade by Lubeluzole

    Article • Cellular Physiology and Biochemistry, January 2018, Karger Publishers

    Dr Francesco Tadini Buoninsegni, Giovanni Lentini

  15. Conformational memory in the association of the transmembrane protein phospholamban with the sarcoplasmic reticulum calcium pump SERCA

    Article • Journal of Biological Chemistry, October 2017, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Francesco Tadini Buoninsegni

  16. Lipoyl-Homotaurine Derivative (ADM_12) Reverts Oxaliplatin-Induced Neuropathy and Reduces Cancer Cells Malignancy by Inhibiting Carbonic Anhydrase IX (CAIX)

    Article • Journal of Medicinal Chemistry, October 2017, American Chemical Society (ACS)

    Dr Francesco Tadini Buoninsegni

  17. Discovery of a new mexiletine-derived agonist of the hERG K + channel

    Article • Biophysical Chemistry, October 2017, Elsevier

    Giovanni Lentini, Dr Francesco Tadini Buoninsegni

  18. Mechanisms of charge transfer in human copper ATPases ATP7A and ATP7B

    Article • IUBMB Life, February 2017, Wiley

    Dr Francesco Tadini Buoninsegni

  19. Effect of cisplatin on the transport activity of PII-type ATPases

    Article • Metallomics, January 2017, Oxford University Press (OUP)

    Dr Francesco Tadini Buoninsegni

  20. Global Analysis of Type Three Secretion System and Quorum Sensing Inhibition of Pseudomonas savastanoi by Polyphenols Extracts from Vegetable Residues

    Article • PLoS ONE, September 2016, PLOS

    Dr Francesco Tadini Buoninsegni

  21. Phospholamban spontaneously reconstitutes into giant unilamellar vesicles where it generates a cation selective channel

    Article • Physical Chemistry Chemical Physics, January 2016, Royal Society of Chemistry

    Dr Francesco Tadini Buoninsegni

  22. Antimony-Phosphomolybdate ATPase Assay

    Article • January 2016, Springer Science + Business Media

    Dr Francesco Tadini Buoninsegni

  23. Electrophysiological Measurements on Solid Supported Membranes

    Article • January 2016, Springer Science + Business Media

    Dr Francesco Tadini Buoninsegni

  24. Hofmeister effect of anions on calcium translocation by sarcoplasmic reticulum Ca2+-ATPase

    Article • Scientific Reports, October 2015, Nature

    Dr Francesco Tadini Buoninsegni

  25. Recording of Pump and Transporter Activity Using Solid-Supported Membranes (SSM-Based Electrophysiology)

    Article • September 2015, Wiley

    Dr Francesco Tadini Buoninsegni

  26. Inhibition of hERG potassium channel by the antiarrhythmic agent mexiletine and its metabolite m-hydroxymexiletine

    Article • Pharmacology Research & Perspectives, July 2015, Wiley

    Dr Francesco Tadini Buoninsegni, Giovanni Lentini

  27. A sulfur-based transport pathway in Cu+-ATPases

    Article • EMBO Reports, May 2015, EMBO

    Dr Francesco Tadini Buoninsegni

  28. Insights on Molecular Determinants of hERG K+ Channel Inhibition: Design, Synthesis, and Biological Evaluation of Lubeluzole Derivatives

    Article • Biophysical Journal, January 2015, Elsevier

    Dr Francesco Tadini Buoninsegni

  29. Biochemical characterization of P-type copper ATPases

    Article • Biochemical Journal, October 2014, Portland Press Ltd.

    Dr Francesco Tadini Buoninsegni

  30. Binding of a Monoclonal Antibody to the Phospholamban Cytoplasmic Domain Interferes with the Channel Activity of Phospholamban Reconstituted in a Tethered Bilayer Lipid Membrane

    Article • Langmuir, September 2014, American Chemical Society (ACS)

    Dr Francesco Tadini Buoninsegni

  31. Anticancer Ruthenium(III) Complex KP1019 Interferes with ATP-Dependent Ca2+Translocation by Sarco-Endoplasmic Reticulum Ca2+-ATPase (SERCA)

    Article • ChemMedChem, June 2014, Wiley

    Dr Francesco Tadini Buoninsegni

  32. Translocation of Platinum Anticancer Drugs by Human Copper ATPases ATP7A and ATP7B

    Article • Angewandte Chemie, December 2013, Wiley

    Dr Francesco Tadini Buoninsegni

  33. Translocation of Platinum Anticancer Drugs by Human Copper ATPases ATP7A and ATP7B

    Article • Angewandte Chemie International Edition, December 2013, Wiley

    Dr Francesco Tadini Buoninsegni

  34. Ca2+/H+ exchange, lumenal Ca2+ release and Ca2+/ATP coupling ratios in the sarcoplasmic reticulum ATPase

    Article • Journal of Cell Communication and Signaling, December 2013, Springer Science + Business Media

    Dr Francesco Tadini Buoninsegni

  35. Enhanced Adsorption of Ca-ATPase Containing Vesicles on a Negatively Charged Solid-Supported-Membrane for the Investigation of Membrane Transporters

    Article • Langmuir, November 2013, American Chemical Society (ACS)

    Dr Francesco Tadini Buoninsegni

  36. Istaroxime stimulates SERCA2a and accelerates calcium cycling in heart failure by relieving phospholamban inhibition

    Article • British Journal of Pharmacology, July 2013, Wiley

    Dr Francesco Tadini Buoninsegni

  37. A Method to Measure Hydrolytic Activity of Adenosinetriphosphatases (ATPases)

    Article • PLoS ONE, March 2013, PLOS

    Dr Francesco Tadini Buoninsegni

  38. Mimicking the Intramolecular Hydrogen Bond: Synthesis, Biological Evaluation, and Molecular Modeling of Benzoxazines and Quinazolines as Potential Antimalarial Agents

    Article • Journal of Medicinal Chemistry, December 2012, American Chemical Society (ACS)

    Dr sandra gemma, Dr Simone Brogi, Dr Stefania Butini, Dr Francesco Tadini Buoninsegni

  39. Distinctive Features of Catalytic and Transport Mechanisms in Mammalian Sarco-endoplasmic Reticulum Ca2+ ATPase (SERCA) and Cu+ (ATP7A/B) ATPases

    Article • Journal of Biological Chemistry, August 2012, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Francesco Tadini Buoninsegni

  40. The Ca2+-ATPase (SERCA1) Is Inhibited by 4-Aminoquinoline Derivatives through Interference with Catalytic Activation by Ca2+, Whereas the ATPase E2 State Remains Functional

    Article • Journal of Biological Chemistry, September 2011, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Francesco Tadini Buoninsegni, Dr sandra gemma, Dr Stefania Butini

  41. The Sodium Pump is Confined in a Phosphoenzyme Form by Lead(II) Ions

    Article • Biophysical Journal, February 2011, Elsevier

    Dr Francesco Tadini Buoninsegni

  42. Charge Movement in Recombinant Copper ATPase is Investigated on a Solid Supported Membrane

    Article • Biophysical Journal, February 2011, Elsevier

    Dr Francesco Tadini Buoninsegni

  43. ATP dependent charge movement in ATP7B Cu+-ATPase is demonstrated by pre-steady state electrical measurements

    Article • FEBS Letters, October 2010, Wiley

    Dr Francesco Tadini Buoninsegni

  44. Confining the Sodium Pump in a Phosphoenzyme Form: The Effect of Lead(II) Ions

    Article • Biophysical Journal, October 2010, Elsevier

    Dr Francesco Tadini Buoninsegni

  45. Inhibition of SERCA1 by a Novel Antimalarial Compound

    Article • Biophysical Journal, January 2010, Elsevier

    Dr sandra gemma, Dr Stefania Butini, Dr Francesco Tadini Buoninsegni

  46. Inhibitory Effect of Pb 2+ on the Transport Cycle of the Na + ,K + -ATPase

    Article • Chemical Research in Toxicology, October 2009, American Chemical Society (ACS)

    Dr Francesco Tadini Buoninsegni

  47. Electrogenic Ion Pumps Investigated on a Solid Supported Membrane: Comparison of Current and Voltage Measurements

    Article • Langmuir, September 2009, American Chemical Society (ACS)

    Dr Francesco Tadini Buoninsegni

  48. High-yield Heterologous Expression of Wild Type and Mutant Ca2+ ATPase: Characterization of Ca2+ Binding Sites by Charge Transfer

    Article • Journal of Molecular Biology, September 2009, Elsevier

    Dr Francesco Tadini Buoninsegni

  49. Charge transfer in P-type ATPases investigated on planar membranes

    Article • Archives of Biochemistry and Biophysics, August 2008, Elsevier

    Dr Francesco Tadini Buoninsegni

  50. Effect of Clotrimazole on the Pump Cycle of the Na,K-ATPase

    Article • Biophysical Journal, August 2008, Elsevier

    Dr Francesco Tadini Buoninsegni

  51. Electrogenic steps of the SR Ca-ATPase enzymatic cycle and the effect of curcumin

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, February 2008, Elsevier

    Dr Francesco Tadini Buoninsegni

  52. Effects of High-Affinity Inhibitors on Partial Reactions, Charge Movements, and Conformational States of the Ca2+ Transport ATPase (Sarco-Endoplasmic Reticulum Ca2+ ATPase)

    Article • Molecular Pharmacology, January 2008, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Dr Francesco Tadini Buoninsegni

  53. Pre-steady State Electrogenic Events of Ca2+/H+ Exchange and Transport by the Ca2+-ATPase

    Article • Journal of Biological Chemistry, October 2006, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Francesco Tadini Buoninsegni

  54. Clotrimazole Inhibits the Ca2+-ATPase (SERCA) by Interfering with Ca2+ Binding and Favoring the E2 Conformation

    Article • Journal of Biological Chemistry, February 2006, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Francesco Tadini Buoninsegni

  55. Photoinduced Electroreduction of Chlorophyllide on Alkanethiol-Coated Mercury

    Article • Journal of the American Chemical Society, February 2005, American Chemical Society (ACS)

    Dr Francesco Tadini Buoninsegni

  56. Time-Resolved Charge Translocation by Sarcoplasmic Reticulum Ca-ATPase Measured on a Solid Supported Membrane

    Article • Biophysical Journal, June 2004, Elsevier

    Dr Francesco Tadini Buoninsegni

  57. Calcium transport by sarcoplasmic reticulum Ca-ATPase can be investigated on a solid-supported membrane

    Article • Bioelectrochemistry, June 2004, Elsevier

    Dr Francesco Tadini Buoninsegni

  58. Two Photobioelectrochemical Applications of Self-Assembled Films on Mercury

    Article • Collection of Czechoslovak Chemical Communications, January 2004, Institute of Organic Chemistry & Biochemistry

    Dr Francesco Tadini Buoninsegni

  59. Electrochemical and photoelectrochemical behavior of chlorophyll a films adsorbed on mercury

    Article • Journal of Electroanalytical Chemistry, July 2003, Elsevier

    Dr Francesco Tadini Buoninsegni

  60. Investigation of Na+,K+-ATPase on a solid supported membrane: the role of acylphosphatase on the ion transport mechanism

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, April 2003, Elsevier

    Dr Francesco Tadini Buoninsegni, Chiara Nediani

  61. Some bioelectrochemical applications of self-assembled films on mercury

    Article • Solid State Ionics, September 2002, Elsevier

    Dr Francesco Tadini Buoninsegni

  62. Photocurrents Generated by Bacteriorhodopsin Adsorbed on Thiol/Lipid Bilayers Supported by Mercury

    Article • Langmuir, August 2002, American Chemical Society (ACS)

    Dr Francesco Tadini Buoninsegni

  63. Monolayers and multilayers of chlorophyl a on a mercury electrode

    Article • Bioelectrochemistry, May 2002, Elsevier

    Dr Francesco Tadini Buoninsegni

  64. DC photoelectric signals from bacteriorhodopsin adsorbed on lipid monolayers and thiol/lipid bilayers supported by mercury

    Article • Bioelectrochemistry, May 2002, Elsevier

    Dr Francesco Tadini Buoninsegni

  65. Bioelectrochemistry at metal∣water interfaces

    Article • Journal of Electroanalytical Chemistry, May 2001, Elsevier

    Dr Francesco Tadini Buoninsegni

  66. Total and free charge densities on mercury coated with self-assembled phosphatidylcholine and octadecanethiol monolayers and octadecanethiol/phosphatidylcholine bilayers

    Article • Journal of Electroanalytical Chemistry, March 2001, Elsevier

    Dr Francesco Tadini Buoninsegni

  67. A voltammetric study of monolayers and bilayers self-assembled on metal electrodes

    Article • Electrochimica Acta, February 2000, Elsevier

    Dr Francesco Tadini Buoninsegni

  68. Bacteriorhodopsin-containing membrane fragments adsorbed on mercury-supported biomimetic membranes

    Article • Electrochemistry Communications, March 1999, Elsevier

    Dr Francesco Tadini Buoninsegni

  69. Alkanethiol monolayers and alkanethiol|phospholipid bilayers supported by mercury: an electrochemical characterization

    Article • Journal of Electroanalytical Chemistry, July 1998, Elsevier

    Dr Francesco Tadini Buoninsegni

  70. Surface Dipole Potential at the Interface between Water and Self-Assembled Monolayers of Phosphatidylserine and Phosphatidic Acid

    Article • Biophysical Journal, May 1998, Elsevier

    Dr Francesco Tadini Buoninsegni

  71. Electron and proton transferring properties of vitamin K1 across a self-assembled phospholipid monolayer

    Article • Journal of Electroanalytical Chemistry, March 1998, Elsevier

    Dr Francesco Tadini Buoninsegni