All Stories

  1. Use of Monte Carlo simulation to determine pharmacodynamic cutoffs of amoxicillin to establish a breakpoint for antimicrobial susceptibility testing in pigs

    Article • American Journal of Veterinary Research, February 2014, American Veterinary Medical Association (AVMA)

    Alain BOUSQUET-MELOU

  2. Low or High Doses of Cefquinome Targeting Low or High Bacterial Inocula Cure Klebsiella pneumoniae Lung Infections but Differentially Impact the Levels of Antibiotic Resistance in Fecal Flora

    Article • Antimicrobial Agents and Chemotherapy, January 2014, ASM Journals

    Alain BOUSQUET-MELOU

  3. Interpreting Bisphenol A Absorption in the Canine Oral Cavity: Gayrard et al. Respond

    Article • Environmental Health Perspectives, December 2013, Environmental Health Perspectives

    Alain BOUSQUET-MELOU

  4. Pharmacokinetic/pharmacodynamic assessment of the effects of parenteral administration of a fluoroquinolone on the intestinal microbiota: Comparison of bactericidal activity at the gut versus the systemic level in a pig model

    Article • International Journal of Antimicrobial Agents, November 2013, Elsevier

    Alain BOUSQUET-MELOU

  5. Persistence and prevalence of pathogenic and extended-spectrum beta-lactamase-producing Escherichia coli in municipal wastewater treatment plant receiving slaughterhouse wastewater

    Article • Water Research, September 2013, Elsevier

    Alain BOUSQUET-MELOU

  6. High Bioavailability of Bisphenol A from Sublingual Exposure

    Article • Environmental Health Perspectives, June 2013, Environmental Health Perspectives

    Alain BOUSQUET-MELOU

  7. The consequences of generic marketing on antibiotic consumption and the spread of microbial resistance: the need for new antibiotics

    Article • Journal of Veterinary Pharmacology and Therapeutics, May 2013, Wiley

    Alain BOUSQUET-MELOU

  8. Should licking behavior be considered in the bioavailability evaluation of transdermal products?

    Article • Journal of Veterinary Pharmacology and Therapeutics, March 2012, Wiley

    Alain BOUSQUET-MELOU

  9. Assessment of the genotoxicity of quinolone and fluoroquinolones contaminated soil with the Vicia faba micronucleus test

    Article • Ecotoxicology and Environmental Safety, February 2012, Elsevier

    Alain BOUSQUET-MELOU

  10. Laparoscopic‐Assisted Colopexy and Sterilization in Male Dogs: Short‐Term Results and Physiologic Consequences

    Article • Veterinary Surgery, April 2011, Wiley

    Alain BOUSQUET-MELOU

  11. Licking behaviour induces partial anthelmintic efficacy of ivermectin pour-on formulation in untreated cattle

    Article • International Journal for Parasitology, April 2011, Elsevier

    Alain BOUSQUET-MELOU

  12. Impact of early versus later fluoroquinolone treatment on the clinical; microbiological and resistance outcomes in a mouse-lung model of Pasteurella multocida infection

    Article • Veterinary Microbiology, March 2011, Elsevier

    Alain BOUSQUET-MELOU

  13. Emergence of Resistant Klebsiella pneumoniae in the Intestinal Tract during Successful Treatment of Klebsiella pneumoniae Lung Infection in Rats

    Article • Antimicrobial Agents and Chemotherapy, May 2010, ASM Journals

    Alain BOUSQUET-MELOU

  14. Species Differences in Pharmacokinetics and Pharmacodynamics

    Article • January 2010, Springer Science + Business Media

    Alain BOUSQUET-MELOU

  15. Influence of Inoculum Size and Marbofloxacin Plasma Exposure on the Amplification of Resistant Subpopulations of Klebsiella pneumoniae in a Rat Lung Infection Model

    Article • Antimicrobial Agents and Chemotherapy, September 2009, ASM Journals

    Alain BOUSQUET-MELOU

  16. Pharmacokinetic/Pharmacodynamic Analysis of the Influence of Inoculum Size on the Selection of Resistance in Escherichia coli by a Quinolone in a Mouse Thigh Bacterial Infection Model

    Article • Antimicrobial Agents and Chemotherapy, June 2009, ASM Journals

    Alain BOUSQUET-MELOU

  17. Relatedness of Escherichia coli Strains with Different Susceptibility Phenotypes Isolated from Swine Feces during Ampicillin Treatment

    Article • Applied and Environmental Microbiology, March 2009, ASM Journals

    Alain BOUSQUET-MELOU

  18. New antibiotics in orphan food-producing animals: What is the responsibility of a Journal regarding good veterinary practice?

    Article • The Veterinary Journal, February 2009, Elsevier

    Alain BOUSQUET-MELOU

  19. Pharmacokinetics of eight anticoagulant rodenticides in mice after single oral administration

    Article • Journal of Veterinary Pharmacology and Therapeutics, September 2008, Wiley

    Alain BOUSQUET-MELOU

  20. Oral absorption of ampicillin: role of paracellular route vs. PepT1 transporter

    Article • Fundamental and Clinical Pharmacology, March 2008, Wiley

    Alain BOUSQUET-MELOU

  21. Induction of the Carrier State in Pigeons Infected with Salmonella enterica Subspecies enterica Serovar Typhimurium PT99 by Treatment with Florfenicol: a Matter of Pharmacokinetics

    Article • Antimicrobial Agents and Chemotherapy, January 2008, ASM Journals

    Alain BOUSQUET-MELOU, Professor Freddy Haesebrouck

  22. AUC/MIC: a PK/PD index for antibiotics with a time dimension or simply a dimensionless scoring factor?

    Article • Journal of Antimicrobial Chemotherapy, October 2007, Oxford University Press (OUP)

    Alain BOUSQUET-MELOU

  23. Influence of Inoculum Size on the Selection of Resistant Mutants of Escherichia coli in Relation to Mutant Prevention Concentrations of Marbofloxacin

    Article • Antimicrobial Agents and Chemotherapy, August 2007, ASM Journals

    Alain BOUSQUET-MELOU

  24. Estimation of absolute oral bioavailability of moxidectin in dogs using a semi‐simultaneous method: influence of lipid co‐administration

    Article • Journal of Veterinary Pharmacology and Therapeutics, July 2007, Wiley

    Alain BOUSQUET-MELOU

  25. Impact of Three Ampicillin Dosage Regimens on Selection of Ampicillin Resistance in Enterobacteriaceae and Excretion of blaTEM Genes in Swine Feces

    Article • Applied and Environmental Microbiology, June 2007, ASM Journals

    Alain BOUSQUET-MELOU

  26. Enrofloxacin and marbofloxacin in horses: comparison of pharmacokinetic parameters, use of urinary and metabolite data to estimate first‐pass effect and absorbed fraction

    Article • Journal of Veterinary Pharmacology and Therapeutics, September 2006, Wiley

    Alain BOUSQUET-MELOU

  27. The Adrenocorticotropin Stimulation Test: Contribution of a Physiologically Based Model Developed in Horse for Its Interpretation in Different Pathophysiological Situations Encountered in Man

    Article • Endocrinology, September 2006, Endocrine Society

    Alain BOUSQUET-MELOU

  28. Contribution of lymphatic transport to the systemic exposure of orally administered moxidectin in conscious lymph duct-cannulated dogs

    Article • European Journal of Pharmaceutical Sciences, January 2006, Elsevier

    Alain BOUSQUET-MELOU

  29. Pharmacokinetics and pharmacodynamics of a therapeutic dose of unfractionated heparin (200 U/kg) administered subcutaneously or intravenously to healthy dogs

    Article • Veterinary Clinical Pathology, September 2005, Wiley

    Alain BOUSQUET-MELOU

  30. Plasma clearance

    Article • Journal of Veterinary Pharmacology and Therapeutics, December 2004, Wiley

    Alain BOUSQUET-MELOU

  31. Bioavailability and its assessment

    Article • Journal of Veterinary Pharmacology and Therapeutics, December 2004, Wiley

    Alain BOUSQUET-MELOU

  32. Volumes of distribution

    Article • Journal of Veterinary Pharmacology and Therapeutics, December 2004, Wiley

    Alain BOUSQUET-MELOU

  33. Plasma terminal half‐life

    Article • Journal of Veterinary Pharmacology and Therapeutics, December 2004, Wiley

    Alain BOUSQUET-MELOU

  34. Endectocide exchanges between grazing cattle after pour-on administration of doramectin, ivermectin and moxidectin

    Article • International Journal for Parasitology, October 2004, Elsevier

    Alain BOUSQUET-MELOU

  35. Population pharmacokinetics of marbofloxacin in horses: preliminary analysis

    Article • Journal of Veterinary Pharmacology and Therapeutics, October 2004, Wiley

    Alain BOUSQUET-MELOU

  36. A pharmacokinetic model to document the actual disposition of topical ivermectin in cattle

    Article • Veterinary Research, July 2003, EDP Sciences

    Alain BOUSQUET-MELOU

  37. Free drug fraction vs. free drug concentration: a matter of frequent confusion

    Article • Journal of Veterinary Pharmacology and Therapeutics, December 2002, Wiley

    Alain BOUSQUET-MELOU

  38. The pharmacokinetic–pharmacodynamic approach to a rational dosage regimen for antibiotics

    Article • Research in Veterinary Science, October 2002, Elsevier

    Alain BOUSQUET-MELOU

  39. Pharmacokinetics of marbofloxacin in horses

    Article • Equine Veterinary Journal, July 2002, Wiley

    Alain BOUSQUET-MELOU

  40. Letter to the Editor

    Article • Journal of Veterinary Pharmacology and Therapeutics, June 2002, Wiley

    Alain BOUSQUET-MELOU

  41. Modelling the loss of metabolic capacities of cultured hepatocytes: application to measurement of Michaelis-Menten kinetic parameters inin vitrosystems

    Article • Xenobiotica, January 2002, Taylor & Francis

    Alain BOUSQUET-MELOU

  42. Licking behaviour and environmental contamination arising from pour-on ivermectin for cattle

    Article • International Journal for Parasitology, December 2001, Elsevier

    Alain BOUSQUET-MELOU

  43. Lipolytic Effects of β1‐, β2‐, and β3‐Adrenergic Agonists in White Adipose Tissue of Mammals

    Article • Annals of the New York Academy of Sciences, May 1998, Wiley

    Alain BOUSQUET-MELOU

  44. Adrenergic regulation of adipocyte metabolism

    Article • Human Reproduction, October 1997, Oxford University Press (OUP)

    Alain BOUSQUET-MELOU

  45. Evidence for numerous brown adipocytes lacking functional beta 3-adrenoceptors in fat pads from nonhuman primates.

    Article • The Journal of Clinical Endocrinology & Metabolism, January 1996, Endocrine Society

    Alain BOUSQUET-MELOU

  46. Adrenergic Receptors and Fat Cells: Differential Recruitment by Physiological Amines and Homologous Regulation

    Article • Obesity Research, November 1995, Wiley

    Alain BOUSQUET-MELOU

  47. Differential activation of β1‐, β2‐ and β3‐adrenoceptors by catecholamines in white and brown adipocytes

    Article • Fundamental and Clinical Pharmacology, July 1995, Wiley

    Alain BOUSQUET-MELOU

  48. Desensitization of β-adrenergic responses in adipocytes involves receptor subtypes and cAMP phosphodiesterase

    Article • European Journal of Pharmacology Molecular Pharmacology, April 1995, Elsevier

    Alain BOUSQUET-MELOU