All Stories

  1. The role of canonical and non-canonical Hedgehog signaling in tumor progression in a mouse model of small cell lung cancer
  2. SnapShot: Phosphoregulation of Mitosis
  3. The role of MDM2 and MDM4 in breast cancer development and prevention
  4. The E3 ubiquitin ligase UBR5 regulates centriolar satellite stability and primary cilia formation via ubiquitylation of CSPP-L.
  5. Mechanisms regulating phosphatase specificity and the removal of individual phosphorylation sites during mitotic exit
  6. PP1 initiates the dephosphorylation of MASTL, triggering mitotic exit and bistability in human cells
  7. Cdc25 Family Phosphatases in Cancer
  8. Dataset from the global phosphoproteomic mapping of early mitotic exit in human cells
  9. How phosphatases generate specificity for substrates
  10. Motifs Regulate Dephosphorylation During Early Mitotic Exit
  11. Degrading Claspin away with Cdh1 and Cyclin A
  12. How common stresses affect mitosis
  13. Partial inhibition of Cdk1 in G2phase overrides the SAC and decouples mitotic events
  14. Quantitative Live Imaging of Endogenous DNA Replication in Mammalian Cells
  15. Greatwall, un nouveau gardien de la mitose
  16. Greatwall, un nouveau gardien de la mitose
  17. Characterization of the Mechanisms Controlling Greatwall Activity
  18. The Substrate of Greatwall Kinase, Arpp19, Controls Mitosis by Inhibiting Protein Phosphatase 2A
  19. Constant regulation of both the MPF amplification loop and the Greatwall-PP2A pathway is required for metaphase II arrest and correct entry into the first embryonic cell cycle
  20. Loss of human Greatwall results in G2 arrest and multiple mitotic defects due to deregulation of the cyclin B-Cdc2/PP2A balance
  21. RSK2 is a kinetochore-associated protein that participates in the spindle assembly checkpoint
  22. Greatwall maintains mitosis through regulation of PP2A
  23. Chfr interacts and colocalizes with TCTP to the mitotic spindle
  24. Pin1 stabilizes Emi1 during G2 phase by preventing its association with SCF βtrcp
  25. Inhibition of S/G2 phase CDK4 reduces mitotic fidelity
  26. Inhibition of S/G2 Phase CDK4 Reduces Mitotic Fidelity
  27. Defining the Chemotherapeutic Targets of Histone Deacetylase Inhibitors
  28. Histone deacetylase inhibitors specifically kill nonproliferating tumour cells
  29. Mechanism of Mitosis-specific Activation of MEK1
  30. Histone Hyperacetylation Induced by Histone Deacetylase Inhibitors Is Not Sufficient to Cause Growth Inhibition in Human Dermal Fibroblasts
  31. Histone Deacetylase Inhibitors Trigger a G2 Checkpoint in Normal Cells That Is Defective in Tumor Cells