All Stories

  1. Redox mechanisms and their pathological role in prion diseases: The road to ruin

    Article • PLoS Pathogens, April 2023, PLOS

    Dr Joern R Steinert

  2. Finding targets and strategies to fight neurodegeneration

    Article • Proceedings of the National Academy of Sciences, March 2021, Proceedings of the National Academy of Sciences

    Dr Joern R Steinert

  3. The C terminus of p73 is essential for hippocampal development

    Article • Proceedings of the National Academy of Sciences, June 2020, Proceedings of the National Academy of Sciences

    Dr Joern R Steinert

  4. Kv3.1 and Kv3.3 subunits differentially contribute to Kv3 channels and action potential repolarization in principal neurons of the auditory brainstem

    Article • The Journal of Physiology, May 2020, Wiley

    Dr Joern R Steinert

  5. Inhibition of neuroinflammatory nitric oxide signalling supresses protein glycation and recovers neuronal dysfunction in prion disease

    Article • April 2020, Research Square

    Dr Joern R Steinert

  6. Drosophila Nrf2/Keap1 Mediated Redox Signaling Supports Synaptic Function and Longevity and Impacts on Circadian Activity

    Article • Frontiers in Molecular Neuroscience, April 2019, Frontiers

    Dr Joern R Steinert

  7. Alterations in neuronal metabolism contribute to the pathogenesis of prion disease

    Article • Cell Death and Differentiation, June 2018, Springer Science + Business Media

    Dr Joern R Steinert

  8. Nitric oxide-mediated posttranslational modifications control neurotransmitter release by modulating complexin farnesylation and enhancing its clamping ability

    Article • PLoS Biology, April 2018, PLOS

    Dr Joern R Steinert

  9. Myostatin-like proteins regulate synaptic function and neuronal morphology

    Article • Development, May 2017, The Company of Biologists

    Dr Joern R Steinert

  10. Activated inhibition in regulating excitability

    Article • The Journal of Physiology, April 2017, Wiley

    Dr Joern R Steinert

  11. M1 muscarinic allosteric modulators slow prion neurodegeneration and restore memory loss

    Article • Journal of Clinical Investigation, December 2016, American Society for Clinical Investigation

    Dr Joern R Steinert

  12. The Amino Acid Transporter JhI-21 Coevolves with Glutamate Receptors, Impacts NMJ Physiology and Influences Locomotor Activity in Drosophila Larvae

    Article • Scientific Reports, January 2016, Springer Science + Business Media

    Dr Joern R Steinert

  13. Nitric Oxide-Mediated Posttranslational Modifications: Impacts at the Synapse

    Article • Oxidative Medicine and Cellular Longevity, January 2016, Hindawi Publishing Corporation

    Dr Joern R Steinert

  14. Nitric Oxide: A Regulator of Cellular Function in Health and Disease

    Article • Oxidative Medicine and Cellular Longevity, January 2016, Hindawi Publishing Corporation

    Dr Joern R Steinert

  15. Synapses and ��-synuclein signalling in disease

    Article • Cogent Biology, September 2015, Taylor & Francis

    Dr Joern R Steinert

  16. Prion protein as a mediator of synaptic transmission

    Article • Communicative & Integrative Biology, July 2015, Taylor & Francis

    Dr Joern R Steinert

  17. Characterisation and comparison of temporal release profiles of nitric oxide generating donors

    Article • Journal of Neuroscience Methods, April 2015, Elsevier

    Dr Joern R Steinert

  18. RBM3 mediates structural plasticity and protective effects of cooling in neurodegeneration

    Article • Nature, January 2015, Nature

    Dr Joern R Steinert

  19. Rab11 modulates  -synuclein-mediated defects in synaptic transmission and behaviour

    Article • Human Molecular Genetics, October 2014, Oxford University Press (OUP)

    Dr Joern R Steinert

  20. Erratum: Corrigendum: Sustained translational repression by eIF2α-P mediates prion neurodegeneration

    Article • Nature, July 2014, Springer Science + Business Media

    Dr Joern R Steinert

  21. Prion protein facilitates synaptic vesicle release by enhancing release probability

    Article • Human Molecular Genetics, April 2014, Oxford University Press (OUP)

    Dr Joern R Steinert

  22. Rab11 as a modulator of synaptic transmission

    Article • Communicative & Integrative Biology, November 2013, Taylor & Francis

    Dr Joern R Steinert

  23. TAp73 knockout mice show morphological and functional nervous system defects associated with loss of p75 neurotrophin receptor

    Article • Proceedings of the National Academy of Sciences, November 2013, Proceedings of the National Academy of Sciences

    Dr Joern R Steinert

  24. Protection from Noise-Induced Hearing Loss by Kv2.2 Potassium Currents in the Central Medial Olivocochlear System

    Article • Journal of Neuroscience, May 2013, Society for Neuroscience

    Dr Joern R Steinert

  25. A gas that ignites a bright spark

    Article • The Journal of Physiology, July 2012, Wiley

    Dr Joern R Steinert

  26. Sustained translational repression by eIF2α-P mediates prion neurodegeneration

    Article • Nature, May 2012, Springer Science + Business Media

    Dr Joern R Steinert

  27. Rab11 rescues synaptic dysfunction and behavioural deficits in a Drosophila model of Huntington's disease

    Article • Human Molecular Genetics, March 2012, Oxford University Press (OUP)

    Dr Joern R Steinert

  28. Nitric Oxide Signalling Augments Neuronal Voltage-Gated L-Type (CaV1) and P/Q-Type (CaV2.1) Channels in the Mouse Medial Nucleus of the Trapezoid Body

    Article • PLoS ONE, February 2012, PLOS

    Dr Joern R Steinert

  29. microRNA-34a regulates neurite outgrowth, spinal morphology, and function

    Article • Proceedings of the National Academy of Sciences, December 2011, Proceedings of the National Academy of Sciences

    Dr Joern R Steinert

  30. Targeting of the Arpc3 actin nucleation factor by miR-29a/b regulates dendritic spine morphology

    Article • The Journal of Cell Biology, September 2011, Rockefeller University Press

    Dr Joern R Steinert

  31. Modulation and control of synaptic transmission across the MNTB

    Article • Hearing Research, September 2011, Elsevier

    Dr Joern R Steinert

  32. Nitric Oxide Is an Activity-Dependent Regulator of Target Neuron Intrinsic Excitability

    Article • Neuron, July 2011, Elsevier

    Dr Joern R Steinert

  33. Early Failure of N-Methyl-d-aspartate Receptors and Deficient Spine Formation Induced by Reduction of Regulatory Heme in Neurons

    Article • Molecular Pharmacology, February 2011, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Dr Joern R Steinert

  34. Acute hyperbilirubinaemia induces presynaptic neurodegeneration at a central glutamatergic synapse

    Article • The Journal of Physiology, November 2010, Wiley

    Dr Joern R Steinert

  35. Mevastatin accelerates loss of synaptic proteins and neurite degeneration in aging cortical neurons in a heme-independent manner

    Article • Neurobiology of Aging, September 2010, Elsevier

    Dr Joern R Steinert

  36. Nitric Oxide Signaling in Brain Function, Dysfunction, and Dementia

    Article • The Neuroscientist, August 2010, SAGE Publications

    Dr Joern R Steinert

  37. Regulation of Kv channel expression and neuronal excitability in rat medial nucleus of the trapezoid body maintained in organotypic culture

    Article • The Journal of Physiology, April 2010, Wiley

    Dr Joern R Steinert

  38. Presynaptic and postsynaptic origin of multicomponent extracellular waveforms at the endbulb of Held-spherical bushy cell synapse

    Article • European Journal of Neuroscience, April 2010, Wiley

    Dr Joern R Steinert

  39. NMDAR-mediated EPSCs are maintained and accelerate in time course during maturation of mouse and rat auditory brainstemin vitro

    Article • The Journal of Physiology, January 2010, Wiley

    Dr Joern R Steinert

  40. Redox Modulation of Ca2+ Signaling in Human Endothelial and Smooth Muscle Cells in Pre-Eclampsia

    Article • Antioxidants & Redox Signaling, May 2009, Mary Ann Liebert Inc

    Dr Joern R Steinert

  41. Nitric Oxide Is a Volume Transmitter Regulating Postsynaptic Excitability at a Glutamatergic Synapse

    Article • Neuron, November 2008, Elsevier

    Dr Joern R Steinert

  42. The hangover gene negatively regulates bouton addition at the Drosophila neuromuscular junction

    Article • Mechanisms of Development, August 2008, Elsevier

    Dr Joern R Steinert

  43. Neurite Degeneration Induced by Heme Deficiency Mediated via Inhibition of NMDA Receptor-Dependent Extracellular Signal-Regulated Kinase 1/2 Activation

    Article • Journal of Neuroscience, August 2007, Society for Neuroscience

    Dr Joern R Steinert

  44. Acceleration of AMPA receptor kinetics underlies temperature-dependent changes in synaptic strength at the rat calyx of Held

    Article • The Journal of Physiology, February 2007, Wiley

    Dr Joern R Steinert

  45. Experience-Dependent Formation and Recruitment of Large Vesicles from Reserve Pool

    Article • Neuron, June 2006, Elsevier

    Dr Joern R Steinert

  46. Early activation of the p42/p44MAPK pathway mediates adenosine-induced nitric oxide production in human endothelial cells: a novel calcium-insensitive mechanism

    Article • The FASEB Journal, October 2002, Federation of American Societies For Experimental Biology (FASEB)

    Dr Joern R Steinert

  47. Growth inhibitory activity of indapamide on vascular smooth muscle cells

    Article • European Journal of Pharmacology, September 2001, Elsevier

    Dr Joern R Steinert