All Stories

  1. Ex Vivo Expansion of CD34+ CD90+ CD49f+ Hematopoietic Stem and Progenitor Cells from Non-enriched Umbilical Cord Blood with Azole Compounds

    Article • Stem Cells Translational Medicine, February 2018, Wiley

    Dr Gigi N Chiu, SHANG LI

  2. Mitochondrial superoxide reduction and cytokine secretion skewing by carbon nanotube scaffolds enhance ex vivo expansion of human cord blood hematopoietic progenitors

    Article • Nanomedicine Nanotechnology Biology and Medicine, October 2015, Elsevier

    Dr Gigi N Chiu

  3. Dual-functionalized poly(amidoamine) dendrimers with poly(ethylene glycol) conjugation and thiolation improved blood compatibility

    Article • Journal of Pharmacy and Pharmacology, August 2015, Wiley

    Dr Gigi N Chiu

  4. Synthesis and biological activity of fluorinated 7-benzylamino-2-phenyl-1,2,4-triazolo[1,5-a][1,3,5]triazin-5-amines

    Article • Journal of Fluorine Chemistry, July 2015, Elsevier

    Dr Gigi N Chiu

  5. Dendrimers in Oral Drug Delivery Application: Current Explorations, Toxicity Issues and Strategies for Improvement

    Article • Current Pharmaceutical Design, May 2015, Bentham Science Publishers

    Dr Gigi N Chiu

  6. Liposomal codelivery of a synergistic combination of bioactive lipids in the treatment of acute myeloid leukemia

    Article • Nanomedicine, August 2014, Future Medicine

    Dr Gigi N Chiu

  7. Discovery of mixed type thymidine phosphorylase inhibitors endowed with antiangiogenic properties: Synthesis, pharmacological evaluation and molecular docking study of 2-thioxo-pyrazolo[1,5-a][1,3,5]triazin-4-ones. Part II

    Article • European Journal of Medicinal Chemistry, May 2014, Elsevier

    Dr Gigi N Chiu

  8. Dual-Functionalized PAMAM Dendrimers with Improved P-Glycoprotein Inhibition and Tight Junction Modulating Effect

    Article • Biomacromolecules, December 2013, American Chemical Society (ACS)

    Dr Gigi N Chiu

  9. Fragment-based approach to the design of 5-chlorouracil-linked-pyrazolo[1,5-a][1,3,5]triazines as thymidine phosphorylase inhibitors

    Article • European Journal of Medicinal Chemistry, December 2013, Elsevier

    Dr Gigi N Chiu

  10. Liposome co-encapsulation of synergistic combination of irinotecan and doxorubicin for the treatment of intraperitoneally grown ovarian tumor xenograft

    Article • Journal of Controlled Release, December 2013, Elsevier

    Dr Gigi N Chiu

  11. Protective role of functionalized single walled carbon nanotubes enhance ex vivo expansion of hematopoietic stem and progenitor cells in human umbilical cord blood

    Article • Nanomedicine Nanotechnology Biology and Medicine, November 2013, Elsevier

    Dr Gigi N Chiu

  12. A structure–activity relationship study of 1,2,4-triazolo[1,5-a][1,3,5]triazin-5,7-dione and its 5-thioxo analogues on anti-thymidine phosphorylase and associated anti-angiogenic activities

    Article • European Journal of Medicinal Chemistry, September 2013, Elsevier

    Dr Gigi N Chiu

  13. Liposomes as sterile preparations and limitations of sterilisation techniques in liposomal manufacturing

    Article • Asian Journal of Pharmaceutical Sciences, April 2013, Elsevier

    Dr Gigi N Chiu

  14. Role of oxidative stress, endoplasmic reticulum stress and ERK activation in triptolide-induced apoptosis

    Article • International Journal of Oncology, March 2013, Spandidos Publications

    Dr Gigi N Chiu

  15. Intercellular cytosolic transfer correlates with mesenchymal stromal cell rescue of umbilical cord blood cell viability during ex vivo expansion

    Article • Cytotherapy, September 2012, Elsevier

    Dr Gigi N Chiu

  16. Lyophilization of cholesterol-free PEGylated liposomes and its impact on drug loading by passive equilibration

    Article • International Journal of Pharmaceutics, July 2012, Elsevier

    Dr Gigi N Chiu

  17. In vivo efficacy of a novel liposomal formulation of safingol in the treatment of acute myeloid leukemia

    Article • Journal of Controlled Release, June 2012, Elsevier

    Dr Gigi N Chiu

  18. Perorally active nanomicellar formulation of quercetin in the treatment of lung cancer

    Article • International Journal of Nanomedicine, February 2012, Taylor & Francis

    Dr Gigi N Chiu

  19. Potent therapeutic activity of folate receptor-targeted liposomal carboplatin in the localized treatment of intraperitoneally grown human ovarian tumor xenograft

    Article • International Journal of Nanomedicine, February 2012, Taylor & Francis

    Dr Gigi N Chiu, Ralph Bunte

  20. Liposome formulation of co-encapsulated vincristine and quercetin enhanced antitumor activity in a trastuzumab-insensitive breast tumor xenograft model

    Article • Nanomedicine Nanotechnology Biology and Medicine, December 2011, Elsevier

    Dr Gigi N Chiu

  21. Increased ERK activation and cellular drug accumulation in the enhanced cytotoxicity of folate receptor-targeted liposomal carboplatin

    Article • International Journal of Oncology, November 2011, Spandidos Publications

    Dr Gigi N Chiu

  22. Multivalent rituximab lipid nanoparticles as improved lymphoma therapies: indirect mechanisms of action andin vivoactivity

    Article • Nanomedicine, November 2011, Future Medicine

    Dr Gigi N Chiu

  23. Functionalized carbon nanomaterials: exploring the interactions with Caco-2 cells for potential oral drug delivery

    Article • International Journal of Nanomedicine, October 2011, Taylor & Francis

    Dr Gigi N Chiu

  24. Effect of triptolide on focal adhesion kinase and survival in MCF-7 breast cancer cells

    Article • Oncology Reports, July 2011, Spandidos Publications

    Dr Gigi N Chiu

  25. Role of reactive oxygen species in the synergistic cytotoxicity of safingol-based combination regimens with conventional chemotherapeutics

    Article • Oncology Letters, June 2011, Spandidos Publications

    Dr Gigi N Chiu

  26. The functional roles of poly(ethylene glycol)‐lipid and lysolipid in the drug retention and release from lysolipid‐containing thermosensitive liposomes in vitro and in vivo

    Article • Journal of Pharmaceutical Sciences, May 2010, Elsevier

    Dr Gigi N Chiu

  27. Simultaneous liposomal delivery of quercetin and vincristine for enhanced estrogen-receptor-negative breast cancer treatment

    Article • Anti-Cancer Drugs, April 2010, Wolters Kluwer Health

    Dr Gigi N Chiu

  28. ChemInform Abstract: Fused Heterocyclic Systems with s-Triazine Ring. Part 14. Synthesis and Heterocyclizations of 3,4-Dihydroquinazolin-2-yl Guanidine in the Search of New Anticancer Agents.

    Article • ChemInform, November 2009, Wiley

    Dr Gigi N Chiu

  29. Lipid-Based Nanoparticulate Systems for the Delivery of Anti-Cancer Drug Cocktails: Implications on Pharmacokinetics and Drug Toxicities

    Article • Current Drug Metabolism, October 2009, Bentham Science Publishers

    Dr Gigi N Chiu

  30. DEVELOPMENT AND CHARACTERIZATION OF A NANOCARRIER FOR QUERCETIN

    Article • International Journal of Nanoscience, February 2009, World Scientific Pub Co Pte Lt

    Dr Gigi N Chiu

  31. Synthesis and Heterocyclizations of 3,4-Dihydroquinazolin-2-yl Guanidine in the Search of New Anticancer Agents

    Article • Heterocycles, January 2009, Japan Institute of Heterocyclic Chemistry

    Dr Gigi N Chiu

  32. ChemInform Abstract: Fused Heterocyclic Systems with s-Triazine Ring. Part 10. Synthesis and Biological Activity of Fluorinated 7-Aryl-2-pyridyl-6,7-dihydro[1,2,4]triazolo[1,5-a] [1,3,5]triazin-5-amines.

    Article • ChemInform, September 2008, Wiley

    Dr Gigi N Chiu

  33. Synthesis and biological activity of fluorinated 7-aryl-2-pyridyl-6,7-dihydro[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-amines

    Article • Journal of Fluorine Chemistry, May 2008, Elsevier

    Dr Gigi N Chiu

  34. Use of a passive equilibration methodology to encapsulate cisplatin into preformed thermosensitive liposomes

    Article • International Journal of Pharmaceutics, February 2008, Elsevier

    Dr Gigi N Chiu

  35. A Cationic Liposomal Vincristine Formulation with Improved Vincristine Retention, Extended Circulation Lifetime and Increased Anti-Tumor Activity

    Article • Letters in Drug Design & Discovery, September 2007, Bentham Science Publishers

    Dr Gigi N Chiu

  36. Optimization and Therapeutic Activity of Liposome-Conjugated Monoclonal Antibodies Against the ErbB family of Receptor Tyrosine Kinases: First Step in the Development of Therapeutic Antibody/Liposomal Anticancer Drug Combinations

    Article • Letters in Drug Design & Discovery, December 2006, Bentham Science Publishers

    Dr Gigi N Chiu

  37. Encapsulation of doxorubicin into thermosensitive liposomes via complexation with the transition metal manganese

    Article • Journal of Controlled Release, May 2005, Elsevier

    Dr Gigi N Chiu

  38. Targeting of antibody conjugated, phosphatidylserine-containing liposomes to vascular cell adhesion molecule 1 for controlled thrombogenesis

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, June 2003, Elsevier

    Dr Gigi N Chiu

  39. Application of purging biotinylated liposomes from plasma to elucidate influx and efflux processes associated with accumulation of liposomes in solid tumors

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, April 2003, Elsevier

    Dr Gigi N Chiu

  40. Development of an in vitro drug release assay that accurately predicts in vivo drug retention for liposome-based delivery systems

    Article • Journal of Controlled Release, December 2002, Elsevier

    Dr Gigi N Chiu

  41. Effects of phosphatidylserine on membrane incorporation and surface protection properties of exchangeable poly(ethylene glycol)-conjugated lipids

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, February 2002, Elsevier

    Dr Gigi N Chiu

  42. Selective protein interactions with phosphatidylserine containing liposomes alter the steric stabilization properties of poly(ethylene glycol)

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, February 2001, Elsevier

    Dr Gigi N Chiu