All Stories

  1. SLE‐DAS remission and low disease activity states discriminate drug from placebo and better health‐related quality of life

    Article • Arthritis Care & Research, January 2024, Wiley

    Prof. Luís Sousa Ines

  2. EULAR recommendations for the management of systemic lupus erythematosus: 2023 update

    Article • Annals of the Rheumatic Diseases, October 2023, BMJ

    Prof. Luís Sousa Ines

  3. What is the best instrument to measure disease activity in SLE? – SLE-DAS vs Easy BILAG

    Article • Autoimmunity Reviews, August 2023, Elsevier

    Prof. Luís Sousa Ines

  4. The SLE-DAS provides an accurate and feasible flare tool in the clinical setting: a validation study

    Article • Rheumatology, July 2023, Oxford University Press (OUP)

    Prof. Luís Sousa Ines

  5. Does remission in systemic lupus erythematosus according to the 2021 DORIS definition match the treating rheumatologist’s judgement?

    Article • Rheumatology, April 2023, Oxford University Press (OUP)

    Prof. Luís Sousa Ines

  6. Predictors of flare in SLE patients fulfilling lupus low disease activity state: a cohort study of 292 patients with 36-month follow-up

    Article • Rheumatology, February 2023, Oxford University Press (OUP)

    Prof. Luís Sousa Ines

  7. Meeting report: the ALPHA project: a stakeholder meeting on lupus clinical trial outcome measures and the patient perspective

    Article • Lupus Science & Medicine, February 2023, BMJ

    Dr. Zahi Touma, Prof. Luís Sousa Ines

  8. Anti-Ku antibody syndrome: is it a distinct clinical entity? A cross-sectional study of 75 patients

    Article • Rheumatology, January 2023, Oxford University Press (OUP)

    Prof. Luís Sousa Ines

  9. Creation and Validation of the European Portuguese Version of the Systemic Lupus Erythematous Quality of Life Questionnaire

    Article • International Journal of Environmental Research and Public Health, January 2023, MDPI AG

    Prof. Luís Sousa Ines

  10. Does expert opinion match the definition of lupus low disease activity state? Prospective analysis of 500 patients from a Spanish multicentre cohort

    Article • Rheumatology, August 2022, Oxford University Press (OUP)

    Prof. Luís Sousa Ines

  11. Predictors of hospitalization in patients with systemic lupus erythematosus: a 10-year cohort study

    Article • Clinical Rheumatology, June 2022, Springer Science + Business Media

    Prof. Luís Sousa Ines

  12. Physician Global Assessment International Standardisation COnsensus in Systemic Lupus Erythematosus: the PISCOS study

    Article • The Lancet Rheumatology, June 2022, Elsevier

    Dr. Zahi Touma, Prof. Luís Sousa Ines

  13. POS0861 ANTI-Ku ANTIBODY SYNDROME: IS IT A DISTINCT CLINICAL ENTITY? A CLUSTER ANALYSIS OF 75 PATIENTS.

    Article • Annals of the Rheumatic Diseases, May 2022, BMJ

    Prof. Luís Sousa Ines

  14. POS0759 DOES LLDAS DEFINITION MATCH THE RHEUMATOLOGIST OPINION? THE FIRST VISIT EVALUATION OF A LONGITUDINAL SPANISH MULTICENTER STUDY TO ASSESS REASONS OF DISAGREEMENT.

    Article • Annals of the Rheumatic Diseases, May 2022, BMJ

    Prof. Luís Sousa Ines

  15. POS0119 SLE-DAS REMISSION AND LOW DISEASE ACTIVITY STATES ARE ASSOCIATED WITH IMPROVED HEALTH-RELATED QUALITY OF LIFE AND FATIGUE: POST-HOC ANALYSIS OF THE BLISS-52 AND BLISS-76 PHASE III TRIALS.

    Article • Annals of the Rheumatic Diseases, May 2022, BMJ

    Prof. Luís Sousa Ines

  16. OP0147 THE SLE-DAS REMISSION AND LOW DISEASE ACTIVITY STATES DISCRIMINATE DRUG FROM PLACEBO AND BETTER HEALTH-RELATED QUALITY OF LIFE: POST-HOC ANALYSIS OF THE BLISS-52 AND BLISS-76 PHASE III TRIALS.

    Article • Annals of the Rheumatic Diseases, May 2022, BMJ

    Prof. Luís Sousa Ines

  17. Definition of low disease activity state based on the SLE-DAS: derivation and validation in a multicentre real-life cohort

    Article • Rheumatology, December 2021, Oxford University Press (OUP)

    Prof. Luís Sousa Ines

  18. Antimalarial treatment and minimizing prednisolone are associated with lower risk of infection in SLE: a 24-month prospective cohort study

    Article • Clinical Rheumatology, November 2021, Springer Science + Business Media

    Prof. Luís Sousa Ines

  19. Systemic Lupus Erythematosus Disease Activity Score (SLE-DAS) enables accurate and user-friendly definitions of clinical remission and categories of disease activity

    Article • Annals of the Rheumatic Diseases, August 2021, BMJ

    Prof. Luís Sousa Ines

  20. POS0762 CAN THE SLE-DAS SUBSTITUTE BILAG TO MEASURE LUPUS DISEASE ACTIVITY IN CLINICAL TRIALS? POST-HOC ANALYSIS OF THE BLISS-76 TRIAL

    Article • Annals of the Rheumatic Diseases, May 2021, BMJ

    Prof. Luís Sousa Ines

  21. OP0293 OPTIMIZING A TOOL TO IDENTIFY LUPUS FLARES IN DAILY CLINICAL PRACTICE: SLE-DAS FLARE VERSUS SELENA FLARE INDEX

    Article • Annals of the Rheumatic Diseases, May 2021, BMJ

    Prof. Luís Sousa Ines

  22. POS0713 PREDICTORS OF HOSPITALIZATION IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS: A 10-YEAR COHORT STUDY OF 398 PATIENTS FROM A TERTIARY CENTRE

    Article • Annals of the Rheumatic Diseases, May 2021, BMJ

    Prof. Luís Sousa Ines

  23. What are the topics you care about making trials in lupus more effective? Results of an Open Space meeting of international lupus experts

    Article • Lupus Science & Medicine, May 2021, BMJ

    Prof. Luís Sousa Ines

  24. Early predictors of renal outcome in patients with proliferative lupus nephritis: a 36-month cohort study

    Article • Rheumatology, February 2021, Oxford University Press (OUP)

    Prof. Luís Sousa Ines

  25. Effectiveness of reproductive health counseling of women with systemic lupus erythematosus: observational cross-sectional study at an academic lupus clinic

    Article • Rheumatology International, August 2020, Springer Science + Business Media

    Prof. Luís Sousa Ines

  26. FRI0155 Α MULTICENTER “AT-RISK” COHORT FOR THE DISCOVERY OF ENVIRONMENTAL, CLINICAL AND MOLECULAR PREDICTORS FOR THE TRANSITION INTO SYSTEMIC LUPUS ERYTHEMATOSUS (SLE)

    Article • Annals of the Rheumatic Diseases, June 2020, BMJ

    Prof. Luís Sousa Ines

  27. SAT0184 MAINTENANCE THERAPY WITH AZATHIOPRINE ASSOCIATED WITH HIGHER RISK OF FLARE IN PROLIFERATIVE LUPUS NEPHRITIS

    Article • Annals of the Rheumatic Diseases, June 2020, BMJ

    Prof. Luís Sousa Ines

  28. OP0092 OPTIMIZING A DEFINITION OF LUPUS LOW DISEASE ACTIVITY STATE (LDA) FOR DAILY CLINICAL PRACTICE: SLE-DAS LDA VS LLDAS

    Article • Annals of the Rheumatic Diseases, June 2020, BMJ

    Prof. Luís Sousa Ines

  29. SAT0185 PREDICTORS OF POOR RENAL OUTCOME IN PATIENTS WITH PROLIFERATIVE LUPUS NEPHRITIS: A 36-MONTHS COHORT STUDY

    Article • Annals of the Rheumatic Diseases, June 2020, BMJ

    Prof. Luís Sousa Ines

  30. FRI0165 RISK OF CKD IN MEMBRANOUS AND PROLIFERATIVE LUPUS NEPHRITIS - ANALYSIS OF A NATIONWIDE MULTICENTRE COHORT

    Article • Annals of the Rheumatic Diseases, June 2020, BMJ

    Prof. Luís Sousa Ines

  31. Response to: ‘Performance of the systemic lupus erythematosus disease activity score (SLE-DAS) in a Latin American population’ by Rodríguez-González et al

    Article • Annals of the Rheumatic Diseases, August 2019, BMJ

    Prof. Luís Sousa Ines

  32. How to investigate: Very early inflammatory rheumatic diseases

    Article • Best Practice & Research Clinical Rheumatology, August 2019, Elsevier

    Prof. Luís Sousa Ines

  33. Response to: ‘SLE-DAS: ready for routine use’ by Mathew et al

    Article • Annals of the Rheumatic Diseases, June 2019, BMJ

    Prof. Luís Sousa Ines

  34. THU0267 THE SLE DISEASE ACTIVITY SCORE (SLE-DAS) ENABLES ACCURATE DEFINITIONS OF SLE REMISSION AND LDA AS ACHIEVABLE TARGETS IN DISEASE MANAGEMENT

    Article • June 2019, BMJ

    Prof. Luís Sousa Ines

  35. Response to: ‘Assessment of responsiveness of the musculoskeletal component of SLE-DAS in an independent cohort’, by Hassan et al

    Article • Annals of the Rheumatic Diseases, April 2019, BMJ

    Prof. Luís Sousa Ines

  36. Performance of SLEDAI-2K to detect a clinically meaningful change in SLE disease activity: a 36–month prospective cohort study of 334 patients

    Article • Lupus, March 2019, SAGE Publications

    Prof. Luís Sousa Ines

  37. IL-12 and IL-23/Th17 axis in systemic lupus erythematosus

    Article • Experimental Biology and Medicine, January 2019, SAGE Publications

    Prof. Luís Sousa Ines

  38. Derivation and validation of the SLE Disease Activity Score (SLE-DAS): a new SLE continuous measure with high sensitivity for changes in disease activity

    Article • Annals of the Rheumatic Diseases, January 2019, BMJ

    Prof. Luís Sousa Ines

  39. AB0215 Association of rheumatoid factor immunoglobulin a seropositivity with risk of erosive arthritis in patients with rheumatoid arthritis: an observational study

    Article • June 2018, BMJ

    Prof. Luís Sousa Ines

  40. FRI0641 Detection of changes in sle disease activity is highly improved with sle-das as compared to sledai: derivation and preliminary validation of the sle disease activity score (SLE-DAS)

    Article • June 2018, BMJ

    Prof. Luís Sousa Ines

  41. Asymptomatic Rhabdomyolysis and Digital Necrosis—Clues for a Rheumatic Disease

    Article • JCR Journal of Clinical Rheumatology, May 2018, Wolters Kluwer Health

    Prof. Luís Sousa Ines

  42. Multitarget therapy of mycophenolate mofetil and cyclosporine A for induction treatment of refractory lupus nephritis

    Article • Lupus, February 2018, SAGE Publications

    Diogo Jesus, Prof. Luís Sousa Ines

  43. Risk of damage and mortality in SLE patients fulfilling the ACR or only the SLICC classification criteria. A 10-year, inception cohort study

    Article • Lupus, September 2017, SAGE Publications

    Prof. Luís Sousa Ines

  44. THU0362 Effect of biotechnological drugs on extra-articular manifestations of ankylosing spondylitis: systematic review

    Article • June 2017, BMJ

    Prof. Luís Sousa Ines

  45. OP0206 Performance of SLEDAI-2K to detect a clinically meaningful change in SLE disease activity: a 36-month prospective cohort study of 334 patients

    Article • June 2017, BMJ

    Prof. Luís Sousa Ines

  46. Central nervous system vasculitis in systemic lupus erythematosus: a case series report in a tertiary referral centre

    Article • Lupus, February 2017, SAGE Publications

    Prof. Luís Sousa Ines

  47. Clinical features and long-term outcomes of systemic lupus erythematosus: comparative data of childhood, adult and late-onset disease in a national register

    Article • Rheumatology International, March 2016, Springer Science + Business Media

    Prof. Luís Sousa Ines

  48. The weaker sex: Characterization of gender disparities in a nationwide lupus register (Reuma.pt/SLE)

    Article • Joint Bone Spine, October 2015, Elsevier

    Prof. Luís Sousa Ines

  49. Performance of SLE Classification Criteria: Are the new SLICC criteria better?

    Article • Arthritis Care & Research, July 2015, Wiley

    Prof. Luís Sousa Ines

  50. AB0608 Greater Organ Involvement and Disease Activity in Childhood-Onset than Adult-Onset With SLE (DATA from Reuma.Pt/Les): Table 1.

    Article • Annals of the Rheumatic Diseases, June 2015, BMJ

    Prof. Luís Sousa Ines

  51. Sera from patients with active systemic lupus erythematosus patients enhance the toll-like receptor 4 response in monocyte subsets

    Article • Journal of Inflammation, May 2015, Springer Science + Business Media

    Prof. Luís Sousa Ines

  52. CD38, CD81 and BAFFR combined expression by transitional B cells distinguishes active from inactive systemic lupus erythematosus

    Article • Clinical and Experimental Medicine, April 2015, Springer Science + Business Media

    Prof. Luís Sousa Ines

  53. Characterization of damage in Portuguese lupus patients: analysis of a national lupus registry

    Article • Lupus, October 2014, SAGE Publications

    Prof. Luís Sousa Ines

  54. THU0026 Greater Diagnostic Delay in Early-Onset than in Late-Onset Systemic Lupus Erythematosus - Data from Reuma.Pt/Les: Table 1.

    Article • Annals of the Rheumatic Diseases, June 2014, BMJ

    Prof. Luís Sousa Ines

  55. THU0011 The SLICC 2012 Classification Criteria Have Higher Sensitivity for SLE than the ACR 1997 Criteria: A Study of 2055 Patients from A Real-Life, Multicenter, International SLE Cohort

    Article • Annals of the Rheumatic Diseases, June 2014, BMJ

    Prof. Luís Sousa Ines

  56. FRI0428 The Weaker Sex: Characterization of Gender Disparities in A Nationwide Lupus Registry (REUMA.PT LES): Table 1.

    Article • Annals of the Rheumatic Diseases, June 2014, BMJ

    Prof. Luís Sousa Ines

  57. Identification of clinical predictors of flare in systemic lupus erythematosus patients: a 24-month prospective cohort study

    Article • Rheumatology, September 2013, Oxford University Press (OUP)

    Prof. Luís Sousa Ines

  58. A5.3 Alterations on Peripheral Blood B Cell Compartments in Systemic Lupus Erythematosus: Relevance For Monitoring Lupus Activity and Therapy

    Article • Annals of the Rheumatic Diseases, February 2013, BMJ

    Prof. Luís Sousa Ines

  59. NK cells dysfunction in systemic lupus erythematosus: relation to disease activity

    Article • Clinical Rheumatology, February 2013, Springer Science + Business Media

    Prof. Luís Sousa Ines

  60. Tolerogenic versus Inflammatory Activity of Peripheral Blood Monocytes and Dendritic Cells Subpopulations in Systemic Lupus Erythematosus

    Article • Clinical and Developmental Immunology, January 2012, Hindawi Publishing Corporation

    Prof. Luís Sousa Ines

  61. PMS30 Cost-Effectiveness of Tocilizumab Compared to Standard Therapeutic Sequences for the Treatment of Moderate/Severe Rheumatoid Arthritis (RA) Patients in Portugal

    Article • Value in Health, November 2011, Elsevier

    Prof. Luís Sousa Ines

  62. Th17 cells in systemic lupus erythematosus share functional features with Th17 cells from normal bone marrow and peripheral tissues

    Article • Clinical Rheumatology, October 2011, Springer Science + Business Media

    Prof. Luís Sousa Ines

  63. The development of a simple questionnaire to screen patients with SLE for the presence of neuropsychiatric symptoms in routine clinical practice

    Article • Lupus, February 2011, SAGE Publications

    Prof. Luís Sousa Ines

  64. Functional characterization of peripheral blood dendritic cells and monocytes in systemic lupus erythematosus

    Article • Rheumatology International, January 2011, Springer Science + Business Media

    Prof. Luís Sousa Ines

  65. Epidemiology of Systemic Lupus Erythematosus

    Article • January 2011, Elsevier

    Prof. Luís Sousa Ines

  66. Frequency and functional activity of Th17, Tc17 and other T-cell subsets in Systemic Lupus Erythematosus

    Article • Cellular Immunology, January 2010, Elsevier

    Prof. Luís Sousa Ines

  67. Undifferentiated connective tissue disease: a seven-center cross-sectional study of 184 patients

    Article • Clinical Rheumatology, April 2009, Springer Science + Business Media

    Prof. Luís Sousa Ines

  68. Soft tissue injections

    Article • Best Practice & Research Clinical Rheumatology, June 2005, Elsevier

    Prof. Luís Sousa Ines

  69. Epidemiology of systemic lupus erythematosus

    Article • January 2004, Elsevier

    Prof. Luís Sousa Ines

  70. Differential Male and Female Adrenal Cortical Steroid Hormone and Cortisol Responses to Interleukin‐6 in Humans

    Article • Annals of the New York Academy of Sciences, June 2002, Wiley

    Prof. Luís Sousa Ines