All Stories

  1. A Stable Micellar Formulation of RAD001 for Intracerebroventricular Delivery and the Treatment of Alzheimer’s Disease and Other Neurological Disorders
  2. Engineering carrier nanoparticles with biomimetic moieties for improved intracellular targeted delivery of mRNA therapeutics and vaccines
  3. A Thermostable Micellar Formulation of Rapalogs for Intracerebroventricular Delivery and the Therapy of Neurological Disorders
  4. Evaluation of β-Lactamase Enzyme Activity in Outer Membrane Vesicles (OMVs) Isolated from Extended Spectrum β-Lactamase (ESBL) Salmonella Infantis Strains
  5. Boosting Immunity and Management against Wheat Fusarium Diseases by a Sustainable, Circular Nanostructured Delivery Platform
  6. Phospholipid fatty acid remodeling and carbonylated protein increase in extracellular vesicles released by airway epithelial cells exposed to cigarette smoke extract
  7. Preface
  8. Sustainable Protocols for Cellulose Nanocrystals Synthesis from Tomato Waste and Their Antimicrobial Properties against Pseudomonas syringae pv. tomato
  9. Extracellular Vesicles in Aging: An Emerging Hallmark?
  10. Turning Microbial AhR Agonists into Therapeutic Agents via Drug Delivery Systems
  11. Biodrug Delivery Systems: Do mRNA Lipid Nanoparticles Come of Age?
  12. Development of a new indole derivative dry powder for inhalation for the treatment of biofilm-associated lung infections
  13. Pulmonary drug delivery technology enables anakinra repurposing in cystic fibrosis
  14. Development and Pharmacokinetics of a Novel Acetylsalicylic Acid Dry Powder for Pulmonary Administration
  15. Aryl Hydrocarbon Receptor Agonism Antagonizes the Hypoxia-driven Inflammation in Cystic Fibrosis
  16. Pharmaceutically Active Microbial AhR Agonists as Innovative Biodrugs in Inflammation
  17. Circular Hazelnut Protection by Lignocellulosic Waste Valorization for Nanopesticides Development
  18. Optimizing therapeutic outcomes of immune checkpoint blockade by a microbial tryptophan metabolite
  19. Preface
  20. Anakinra restores cellular proteostasis by coupling mitochondrial redox balance to autophagy
  21. Effects of Titanium Dioxide Nanoparticles on Porcine Prepubertal Sertoli Cells: An “In Vitro” Study
  22. SBA15-supported nano-ruthenium catalyst for the oxidative cleavage of alkenes to aldehydes under flow conditions
  23. Drug-Induced Lysosomal Impairment Is Associated with the Release of Extracellular Vesicles Carrying Autophagy Markers
  24. Defective Glyoxalase 1 Contributes to Pathogenic Inflammation in Cystic Fibrosis
  25. Preface
  26. Dry Powder Inhalers in the Digitalization Era: Current Status and Future Perspectives
  27. Development and in vitro-in vivo performances of an inhalable indole-3-carboxaldehyde dry powder to target pulmonary inflammation and infection
  28. Rojo Duro Red Onion Extract Loaded Spray Thermogel as a Sustainable Platform for the Treatment of Oral Mucosa Lesions
  29. A Green Nanostructured Pesticide to Control Tomato Bacterial Speck Disease
  30. Pharyngeal Microbial Signatures Are Predictive of the Risk of Fungal Pneumonia in Hematologic Patients
  31. Indole-3-Carboxaldehyde Restores Gut Mucosal Integrity and Protects from Liver Fibrosis in Murine Sclerosing Cholangitis
  32. Targeted Drug Delivery Technologies Potentiate the Overall Therapeutic Efficacy of an Indole Derivative in a Mouse Cystic Fibrosis Setting
  33. Anakinra Activates Superoxide Dismutase 2 to Mitigate Inflammasome Activity
  34. Regulation of host physiology and immunity by microbial indole-3-aldehyde
  35. Enteric formulated indole-3-carboxaldehyde targets the aryl hydrocarbon receptor for protection in a murine model of metabolic syndrome
  36. Ethidium bromide exposure unmasks an antibiotic efflux system in Rhodococcus equi
  37. Tackling Immune Pathogenesis of COVID-19 through Molecular Pharmaceutics
  38. Lipotoxic stress alters the membrane lipid profile of extracellular vesicles released by Huh-7 hepatocarcinoma cells
  39. Optimized Extraction of Amikacin from Murine Whole Blood
  40. Initial In Vivo Evaluation of a Novel Amikacin-Deoxycholate Hydrophobic Salt Delivers New Insights on Amikacin Partition in Blood and Tissues
  41. In “Vitro” Lps-Stimulated Sertoli Cells Pre-Loaded With Microparticles: Intracellular Activation Pathways
  42. Selectively targeting key inflammatory pathways in cystic fibrosis
  43. Evolutionary Algorithms in Modeling Aerodynamic Properties of Spray-Dried Microparticulate Systems
  44. Meet Our Editorial Board Member
  45. Preface
  46. Redox-Sensitive Glyoxalase 1 Up-Regulation Is Crucial for Protecting Human Lung Cells from Gold Nanoparticles Toxicity
  47. Postbiotic-Enabled Targeting of the Host-Microbiota-Pathogen Interface: Hints of Antibiotic Decline?
  48. Tryptophan as a Central Hub for Host/Microbial Symbiosis
  49. An Inhalable Theranostic System for Local Tuberculosis Treatment Containing an Isoniazid Loaded Metal Organic Framework Fe-MIL-101-NH2—From Raw MOF to Drug Delivery System
  50. Phenotypic Characterization of Rhodococcus equi Biofilm Grown In Vitro and Inhibiting and Dissolving Activity of Azithromycin/Rifampicin Treatment
  51. Development and characterization of mucoadhesive-thermoresponsive gels for the treatment of oral mucosa diseases
  52. Preface
  53. Meeting the unmet: from traditional to cutting-edge techniques for poly lactide and poly lactide-co-glycolide microparticle manufacturing
  54. Exploring the Nano Spray-Drying Technology as an Innovative Manufacturing Method for Solid Lipid Nanoparticle Dry Powders
  55. Early intrathecal infusion of everolimus restores cognitive function and mood in a murine model of Alzheimer's disease
  56. Probing Internalization Effects and Biocompatibility of Ultrasmall Zirconium Metal-Organic Frameworks UiO-66 NP in U251 Glioblastoma Cancer Cells
  57. A Novel Stabilizing Approach to Improve the Manufacturing of Biodegradable Microparticles Entrapping Plasticizing Active Molecules: the Case of 4-Methoxychalcone
  58. Development of Novel Indole-3-Aldehyde–Loaded Gastro-Resistant Spray-Dried Microparticles for Postbiotic Small Intestine Local Delivery
  59. In vitro performances of novel co-spray-dried azithromycin/rifampicin microparticles for Rhodococcus equi disease treatment
  60. Reply to ‘F508del-CFTR is not corrected by thymosin α1’
  61. Testosterone and FSH modulate Sertoli cell extracellular secretion: Proteomic analysis
  62. Crystallization
  63. Physical Properties Characterization
  64. Biopharmaceutical Processes
  65. Particle Size Measurement
  66. Pharmaceutical Powder and Particles
  67. Solid-State Chemistry
  68. General Conclusion
  69. Introduction
  70. Towards Targeting the Aryl Hydrocarbon Receptor in Cystic Fibrosis
  71. Fundamentals of Particle Interactions
  72. Particle Size and Distribution
  73. Recent and Evolving Manufacturing Processes
  74. Extracellular vesicles released by fibroblasts undergoing H-Ras induced senescence show changes in lipid profile
  75. Reshaping antibiotics through hydrophobic drug-bile acid ionic complexation enhances activity against Staphylococcus aureus biofilms
  76. TFEB activation restores migration ability to Tsc1-deficient adult neural stem/progenitor cells
  77. The long and winding road to inhaled TB therapy: not only the bug’s fault
  78. Extremely Active, Tunable, and pH-Responsive Iridium Water Oxidation Catalysts
  79. Ion Pairing for Controlling Drug Delivery
  80. Rapamycin-loaded solid lipid nanoparticles: Morphology and impact of the drug loading on the phase transition between lipid polymorphs
  81. Rapamycin Loaded Solid Lipid Nanoparticles as a New Tool to Deliver mTOR Inhibitors: Formulation and in Vitro Characterization
  82. Intraperitoneal injection of microencapsulated Sertoli cells restores muscle morphology and performance in dystrophic mice
  83. β-cyclodextrin hinders PLGA plasticization during microparticle manufacturing
  84. Effects of intraperitoneal injection of microencapsulated Sertoli cells on chronic and presymptomatic dystrophic mice
  85. Drug delivery system innovation and Health Technology Assessment: Upgrading from Clinical to Technological Assessment
  86. Alginate beads as a carrier for omeprazole/SBA-15 inclusion compound: A step towards the development of personalized paediatric dosage forms
  87. Alginates in Pharmaceutics and Biomedicine: Is the Future so Bright?
  88. Powder, capsule and device: An imperative ménage à trois for respirable dry powders
  89. Long-term stability, functional competence, and safety of microencapsulated specific pathogen-free neonatal porcine Sertoli cells: a potential product for cell transplant therapy
  90. Silica nanoparticles assisted photodegradation of acridine orange in aqueous suspensions
  91. Stem cells from human amniotic fluid exert immunoregulatory function via secreted indoleamine 2,3‐dioxygenase1
  92. Evaluation of a LC–MS method for everolimus preclinical determination in brain by using [13C2D4]RAD001 internal standard
  93. Reaction kinetics and targeting to cellular glutathione S-transferase of the glutathione peroxidase mimetic PhSeZnCl and its d,l-polylactide microparticle formulation
  94. In vitro–in vivo correlation from lactide-co-glycolide polymeric dosage forms
  95. Microparticle-loaded neonatal porcine Sertoli cells for cell-based therapeutic and drug delivery system
  96. Chitosan films containing mesoporous SBA-15 supported silver nanoparticles for wound dressing
  97. Capreomycin inhalable powders prepared with an innovative spray-drying technique
  98. The Influence of Feedstock and Process Variables on the Encapsulation of Drug Suspensions by Spray‐Drying in Fast Drying Regime: The Case of Novel Antitubercular Drug–Palladium Complex Containing Polymeric Microparticles
  99. Development of Risperidone PLGA Microspheres
  100. IVIVC from Long Acting Olanzapine Microspheres
  101. Synthesis, characterization and in vitro extracellular and intracellular activity against Mycobacterium tuberculosis infection of new second-line antitubercular drug-palladium complexes
  102. Lipid nanoparticles for brain targeting II. Technological characterization
  103. Preparation, Characterization, and In Vivo Evaluation of Olanzapine Poly(D,L-lactide-co-glycolide) Microspheres
  104. Capreomycin supergenerics for pulmonary tuberculosis treatment: Preparation, in vitro, and in vivo characterization
  105. Colloidal nickel(0)-carboxymethyl cellulose particles: A biopolymer-inorganic catalyst for hydrogenation of nitro-aromatics and carbonyl compounds
  106. Development of a spray-drying method for the formulation of respirable microparticles containing ofloxacin–palladium complex
  107. Conformal polymer coatings for pancreatic islets transplantation
  108. Response to Comment on Blasi et al. (2011) “Lipid nanoparticles for brain targeting I. Formulation optimization”
  109. Synthesis of colloidal dispersions of NiAl, ZnAl, NiCr, ZnCr, NiFe, and MgFe hydrotalcite-like nanoparticles
  110. The real value of novel particulate carriers for sunscreen formulation
  111. Lipid nanoparticles for brain targeting I. Formulation optimization
  112. Solid Lipid Nanoparticles to Improve Brain Drug Delivery
  113. Development of a scalable procedure for fine calcium alginate particle preparation
  114. Formulation and Release Behavior of Doxycycline–Alginate Hydrogel Microparticles Embedded into Pluronic F127 Thermogels as a Potential New Vehicle for Doxycycline Intradermal Sustained Delivery
  115. Simple and scalable method for peptide inhalable powder production
  116. Bioactive Long-Term Release from Biodegradable Microspheres Preserves Implanted ALG-PLO-ALG Microcapsules from In Vivo Response to Purified Alginate
  117. Fighting tuberculosis: old drugs, new formulations
  118. Lipid Nanoparticles for Drug Delivery to the Brain: In Vivo Veritas
  119. Formulation studies of benzydamine mucoadhesive formulations for vaginal administration
  120. Novel composite microparticles for protein stabilization and delivery
  121. Eudragit® and hydrotalcite-like anionic clay composite system for diclofenac colonic delivery
  122. Influence of Compression Force on The Behavior of Mucoadhesive Buccal Tablets
  123. Physicochemical characterization and release mechanism of a novel prednisone biodegradable microsphere formulation
  124. Solid Lipid Nanoparticles for Targeted Brain Drug Delivery
  125. Improvement of dissolution rate of piroxicam by inclusion into MCM-41 mesoporous silicate
  126. Mucoadhesive bilayered tablets for buccal sustained release of flurbiprofen
  127. Modification of theophylline release with alginate gel formed in hard capsules
  128. Solid lipid nanoparticles for targeted brain drug delivery☆
  129. Ketoprofen poly(lactide-co-glycolide) physical interaction
  130. Preparation of large porous biodegradable microspheres by using a simple double-emulsion method for capreomycin sulfate pulmonary delivery
  131. Preparation and in vitro and in vivo characterization of composite microcapsules for cell encapsulation
  132. Delivering Drugs to the Central Nervous System: A Medicinal Chemistry or a Pharmaceutical Technology Issue?
  133. Development of liposomal capreomycin sulfate formulations: Effects of formulation variables on peptide encapsulation
  134. Evaluation and Optimization of the Conditions for an Improved Ferulic Acid Intercalation into a Synthetic Lamellar Anionic Clay
  135. Ketoprofen controlled release from composite microcapsules for cell encapsulation: Effect on post-transplant acute inflammation
  136. Long-term delivery of superoxide dismutase and catalase entrapped in poly(lactide-co-glycolide) microspheres: In vitro effects on isolated neonatal porcine pancreatic cell clusters
  137. Evaluation of Indomethacin Percutaneous Absorption from Nanostructured Lipid Carriers (NLC): In Vitro and In Vivo Studies
  138. Biodegradable microspheres as carriers for native superoxide dismutase and catalase delivery
  139. UV spectroscopy and reverse-phase HPLC as novel methods to determine Capreomycin of liposomal fomulations
  140. Development of mucoadhesive patches for buccal administration of ibuprofen
  141. Potential prodrugs of non-steroidal anti-inflammatory agents for targeted drug delivery to the CNS
  142. Leucinostatin-A loaded nanospheres: characterization and in vivo toxicity and efficacy evaluation
  143. Novel mucoadhesive buccal formulation containing metronidazole for the treatment of periodontal disease
  144. Unilamellar vesicles as potential capreomycin sulfate carriers: Preparation and physicochemical characterization
  145. Multifunctional microcapsules for pancreatic islet cell entrapment: design, preparation and in vitro characterization
  146. Preparation and characterization of poly(D,L-lactide-co-glycolide) microspheres for controlled release of human growth hormone