All Stories

  1. A Focused Screen Identifies Antifolates with Activity on Mycobacterium tuberculosis

    Article • ACS Infectious Diseases, December 2015, American Chemical Society (ACS)

    Dr Luis Ballell

  2. Whole Cell Target Engagement Identifies Novel Inhibitors of Mycobacterium tuberculosis Decaprenylphosphoryl-β- d -ribose Oxidase

    Article • ACS Infectious Diseases, December 2015, American Chemical Society (ACS)

    Dr Luis Ballell

  3. Non-absorbable mesoporous silica for the development of protein sequestration therapies

    Article • Biochemical and Biophysical Research Communications, December 2015, Elsevier

    Dr Luis Ballell

  4. Carbamoyl Triazoles, Known Serine Protease Inhibitors, Are a Potent New Class of Antimalarials

    Article • Journal of Medicinal Chemistry, August 2015, American Chemical Society (ACS)

    Dr Luis Ballell

  5. Hydrolysis of Clavulanate by Mycobacterium tuberculosis β-Lactamase BlaC Harboring a Canonical SDN Motif

    Article • Antimicrobial Agents and Chemotherapy, July 2015, ASM Journals

    Dr Luis Ballell

  6. A Developability-Focused Optimization Approach Allows Identification of in Vivo Fast-Acting Antimalarials: N -[3-[(Benzimidazol-2-yl)amino]propyl]amides

    Article • Journal of Medicinal Chemistry, June 2015, American Chemical Society (ACS)

    Dr Luis Ballell

  7. Combinations of β-Lactam Antibiotics Currently in Clinical Trials Are Efficacious in a DHP-I-Deficient Mouse Model of Tuberculosis Infection

    Article • Antimicrobial Agents and Chemotherapy, May 2015, ASM Journals

    Dr Luis Ballell

  8. Design, Synthesis, and Evaluation of New Thiadiazole-Based Direct Inhibitors of Enoyl Acyl Carrier Protein Reductase (InhA) for the Treatment of Tuberculosis

    Article • Journal of Medicinal Chemistry, January 2015, American Chemical Society (ACS)

    Dr Luis Ballell

  9. Mycobacterium tuberculosis Gyrase Inhibitors as a New Class of Antitubercular Drugs

    Article • Antimicrobial Agents and Chemotherapy, January 2015, ASM Journals

    Miss Esther Perez-Herran, Dr Luis Ballell

  10. Rapid Cytolysis of Mycobacterium tuberculosis by Faropenem, an Orally Bioavailable β-Lactam Antibiotic

    Article • Antimicrobial Agents and Chemotherapy, November 2014, ASM Journals

    Dr Luis Ballell

  11. Biochemical and Structural Characterization of Mycobacterial Aspartyl-tRNA Synthetase AspS, a Promising TB Drug Target

    Article • PLoS ONE, November 2014, PLOS

    Dr Luis Ballell

  12. Testing Tuberculosis Drug Efficacy in a Zebrafish High-Throughput Translational Medicine Screen

    Article • Antimicrobial Agents and Chemotherapy, November 2014, ASM Journals

    Dr Luis Ballell

  13. High-Content Screening Technology Combined with a Human Granuloma Model as a New Approach To Evaluate the Activities of Drugs against Mycobacterium tuberculosis

    Article • Antimicrobial Agents and Chemotherapy, October 2014, ASM Journals

    Dr Luis Ballell

  14. Encapsulation of Anti-Tuberculosis Drugs within Mesoporous Silica and Intracellular Antibacterial Activities

    Article • Nanomaterials, September 2014, MDPI AG

    Dr Luis Ballell

  15. Large pore mesoporous silica induced weight loss in obese mice

    Article • Nanomedicine, July 2014, Future Medicine

    Dr Luis Ballell

  16. Encoded Library Technology as a Source of Hits for the Discovery and Lead Optimization of a Potent and Selective Class of Bactericidal Direct Inhibitors of Mycobacterium tuberculosis InhA

    Article • Journal of Medicinal Chemistry, February 2014, American Chemical Society (ACS)

    Dr Luis Ballell

  17. Collaborative approaches for Target ID in neglected diseases: identifying new antimalarial targets

    Article • Malaria Journal, January 2014, Springer Science + Business Media

    Dr Luis Ballell

  18. Tetrahydropyrazolo[1,5-a]Pyrimidine-3-Carboxamide and N-Benzyl-6′,7′-Dihydrospiro[Piperidine-4,4′-Thieno[3,2-c]Pyran] Analogues with Bactericidal Efficacy against Mycobacterium tuberculosis Targeting MmpL3

    Article • PLoS ONE, April 2013, PLOS

    Dr Luis Ballell

  19. Discovery of novel InhA reductase inhibitors: application of pharmacophore- and shape-based screening approach

    Article • Future Medicinal Chemistry, March 2013, Future Science

    Dr Luis Ballell

  20. Improved BM212 MmpL3 Inhibitor Analogue Shows Efficacy in Acute Murine Model of Tuberculosis Infection

    Article • PLoS ONE, February 2013, PLOS

    Dr Luis Ballell

  21. Fueling Open-Source Drug Discovery: 177 Small-Molecule Leads against Tuberculosis

    Article • ChemMedChem, January 2013, Wiley

    Dr Luis Ballell

  22. In vivo oral toxicological evaluation of mesoporous silica particles

    Article • Nanomedicine, January 2013, Future Medicine

    Dr Luis Ballell

  23. Identification of Novel Imidazo[1,2-a]pyridine Inhibitors Targeting M. tuberculosis QcrB

    Article • PLoS ONE, December 2012, PLOS

    Dr Luis Ballell

  24. In vivo Enhancement in Bioavailability of Atazanavir in the Presence of Proton-Pump Inhibitors using Mesoporous Materials

    Article • ChemMedChem, December 2011, Wiley

    Dr Luis Ballell

  25. 4-Substituted Thioquinolines and Thiazoloquinolines: Potent, Selective, and Tween-80 in vitro Dependent Families of Antitubercular Agents with Moderate in vivo Activity

    Article • ChemMedChem, September 2011, Wiley

    Dr Luis Ballell

  26. ChemInform Abstract: Iodine and Its Interhalogen Compounds. Versatile Reagents in Carbohydrate Chemistry. Part 14. Glycosylated Amino Acid Synthesis.

    Article • ChemInform, May 2010, Wiley

    Dr Luis Ballell

  27. Synthesis and Evaluation of New Thiodigalactoside-Based Chemical Probes to Label Galectin-3

    Article • ChemBioChem, July 2009, Wiley

    Dr Luis Ballell

  28. New Thiopyrazolo[3,4-d]pyrimidine Derivatives as Antimycobacterial Agents.

    Article • ChemInform, July 2007, Wiley

    Dr Luis Ballell

  29. New Small-Molecule Synthetic Antimycobacterials

    Article • Antimicrobial Agents and Chemotherapy, May 2007, ASM Journals

    Dr Luis Ballell

  30. New thiopyrazolo[3,4-d]pyrimidine derivatives as anti-mycobacterial agents

    Article • Bioorganic & Medicinal Chemistry Letters, March 2007, Elsevier

    Dr Luis Ballell

  31. A new chemical probe for the detection of the cancer-linked galectin-3

    Article • Organic & Biomolecular Chemistry, January 2006, Royal Society of Chemistry

    Dr Luis Ballell

  32. New Small-Molecule Synthetic Antimycobacterials

    Article • Antimicrobial Agents and Chemotherapy, May 2005, ASM Journals

    Dr Luis Ballell

  33. Cover Picture: A New Chemical Probe for Proteomics of Carbohydrate-Binding Proteins (ChemBioChem 2/2005)

    Article • ChemBioChem, January 2005, Wiley

    Dr Luis Ballell

  34. Synthesis and evaluation of mimetics of UDP and UDP-α-d-galactose, dTDP and dTDP-α-d-glucose with monosaccharides replacing the key pyrophosphate unit

    Article • Organic & Biomolecular Chemistry, January 2005, Royal Society of Chemistry

    Dr Luis Ballell

  35. Microwave-Assisted, Tin-Mediated, Regioselective 3-O-Alkylation of Galactosides.

    Article • ChemInform, December 2004, Wiley

    Dr Luis Ballell

  36. A New Chemical Probe for Proteomics of Carbohydrate-Binding Proteins

    Article • ChemBioChem, December 2004, Wiley

    Dr Luis Ballell

  37. Microwave-assisted, tin-mediated, regioselective 3-O-alkylation of galactosides

    Article • Tetrahedron Letters, August 2004, Elsevier

    Dr Luis Ballell

  38. Amino alditols as inhibitors of mycobacterial cell wall biosynthesis

    Article • Biochemical Society Transactions, February 2002, Portland Press Ltd.

    Dr Luis Ballell

  39. Iodine and its interhalogen compounds: versatile reagents in carbohydrate chemistry. XIV. Glycosylated amino acid synthesis

    Article • Journal of the Chemical Society Perkin Transactions 1, January 2001, Royal Society of Chemistry

    Dr Luis Ballell