All Stories

  1. USP14 regulates DNA damage repair by targeting RNF168-dependent ubiquitination
  2. Autophagy as a mechanism of Apo2L/TRAIL resistance
  3. Development of venetoclax for therapy of lymphoid malignancies
  4. Idelalisib therapy of indolent B-cell malignancies: chronic lymphocytic leukemia and small lymphocytic or follicular lymphomas
  5. miR-377-dependent BCL-xL regulation drives chemotherapeutic resistance in B-cell lymphoid malignancies
  6. Cyclin E/Cdk2-dependent phosphorylation of Mcl-1 determines its stability and cellular sensitivity to BH3 mimetics
  7. Surface Levels of CD20 Determine Anti-CD20 Antibodies Mediated Cell Death In Vitro
  8. Caspase-3 Activation Is a Critical Determinant of Genotoxic Stress-Induced Apoptosis
  9. New agents for the treatment of lymphoid leukemia and lymphoma: focus on recent FDA approvals
  10. Autophagic flux determines cell death and survival in response to Apo2L/TRAIL (dulanermin)
  11. Defective chromatin recruitment and retention of NHEJ core components in human tumor cells expressing a Cyclin E fragment
  12. The phosphatidylinositol 3‐kinases (PI3K) inhibitor GS‐1101 synergistically potentiates histone deacetylase inhibitor‐induced proliferation inhibition and apoptosis through the inactivation of PI3K...
  13. BECN1 and BIM interactions with MCL-1 determine fludarabine resistance in leukemic B cells
  14. PARP Inhibition Sensitizes to Low Dose-Rate Radiation TMPRSS2-ERG Fusion Gene-Expressing and PTEN-Deficient Prostate Cancer Cells
  15. The Investigational Aurora Kinase A Inhibitor MLN8237 Induces Defects in Cell Viability and Cell-Cycle Progression in Malignant Bladder Cancer Cells In Vitro and In Vivo
  16. Hyperammonemia-mediated autophagy in skeletal muscle contributes to sarcopenia of cirrhosis
  17. Mcl-1 Phosphorylation Defines ABT-737 Resistance That Can Be Overcome by Increased NOXA Expression in Leukemic B cells
  18. Analysis of apoptosis methods recently used in Cancer Research and Cell Death & Disease publications
  19. Autophagy-dependent senescence in response to DNA damage and chronic apoptotic stress
  20. Histone H2AX Phosphorylation: A Marker for DNA Damage
  21. Future of radiation therapy for malignant melanoma in an era of newer, more effective biological agents
  22. An antiapoptotic BCL-2 family expression index predicts the response of chronic lymphocytic leukemia to ABT-737
  23. The Evolving Role of Radiation Therapy in the Management of Malignant Melanoma
  24. HDAC inhibitors potentiate the apoptotic effect of enzastaurin in lymphoma cells
  25. Anti-malaria drug blocks proteotoxic stress response: Anti-cancer implications
  26. Combining 2-deoxy-D-glucose with electron transport chain blockers: A double-edged sword
  27. A C-terminal Fragment of Cyclin E, Generated by Caspase-mediated Cleavage, Is Degraded in the Absence of a Recognizable Phosphodegron
  28. Regulation of CD20 expression by radiation-induced changes in intracellular redox status
  29. IFN- γ Induces Apoptosis in HL-60 Cells Through Decreased Bcl-2 and Increased Bak Expression
  30. Caspase-3 Activation is a Critical Determinant of Genotoxic Stress-Induced Apoptosis
  31. Chapter 6 DNA Damage Response and Apoptosis
  32. Requirement of Catalytically Active Tyk2 and Accessory Signals for the Induction of TRAIL mRNA by IFN- β
  33. A Jekyll and Hyde Role of Cyclin E in the Genotoxic Stress Response: Switching from Cell Cycle Control to Apoptosis Regulation
  34. E2F4 Function in G2 Maintaining G2-arrest to Prevent Mitotic Entry with Damaged DNA
  35. S-phase checkpoints regulate Apo2 ligand/TRAIL and CPT-11–induced apoptosis of prostate cancer cells
  36. Interaction of a Cyclin E Fragment with Ku70 Regulates Bax-Mediated Apoptosis
  37. E2F4 regulates a stable G2 arrest response to genotoxic stress in prostate carcinoma
  38. Sensitization of prostate carcinoma cells to Apo2L/TRAIL by a Bcl-2 family protein inhibitor
  39. Proteolytic Cleavage of the p65-RelA Subunit of NF-κB during Poliovirus Infection
  40. Superoxide Dismutase Inactivation in Pathophysiology of Asthmatic Airway Remodeling and Reactivity
  41. Expression and Regulation of Death Receptors in Multiple Myeloma and Prostate Carcinoma
  42. Opposing roles of E2Fs in cell proliferation and death
  43. Apoptosis of Multiple Myeloma
  44. Effects of resveratrol on gene expression in renal cell carcinoma
  45. Microarray gene expression profiling and analysis in renal cell carcinoma
  46. A Dual Role of Cyclin E in Cell Proliferation and Apotosis May Provide a Target for Cancer Therapy
  47. p53 Binding to Target Sites Is Dynamically Regulated Before and After Ionizing Radiation-Mediated DNA Damage
  48. Essential role of the voltage-dependent anion channel (VDAC) in mitochondrial permeability transition pore opening and cytochrome c release induced by arsenic trioxide
  49. Sustained apoptosis in human cardiac allografts despite histologic resolution of rejection1
  50. Apo2L/TRAIL: apoptosis signaling, biology, and potential for cancer therapy
  51. The late increase in intracellular free radical oxygen species during apoptosis is associated with cytochrome c release, caspase activation, and mitochondrial dysfunction
  52. Redox regulation of apoptosis before and after cytochrome C release
  53. Role of Apo2L/TRAIL and Bcl-2-family Proteins in Apoptosis of Multiple Myeloma
  54. Proteolytic Cleavage of Cyclin E Leads to Inactivation of Associated Kinase Activity and Amplification of Apoptosis in Hematopoietic Cells
  55. Inositol hexakisphosphate kinase 2 sensitizes ovarian carcinoma cells to multiple cancer therapeutics
  56. Is Caspase-8 a Neuroendocrine Lung Tumor Suppressor?
  57. Apoptosis in cardiac allograft rejection and its response to treatment
  58. The Late Increase of Free Radicals During Genotoxic-Stress Induced Apoptosis is Associated with Cytochrome C Release From Mitochondria Induced by Caspase-Mediated Feedback Loop Amplification
  59. Genomic Organization and Transcriptional Regulation of Human Apo2/TRAIL Gene
  60. Cyclin E induction by genotoxic stress leads to apoptosis of hematopoietic cells
  61. Cellular Commitment to Radiation-Induced Apoptosis
  62. Distinct stages of cytochrome c release from mitochondria: evidence for a feedback amplification loop linking caspase activation to mitochondrial dysfunction in genotoxic stress induced apoptosis
  63. Ionizing Radiation Stimulates Mitochondrial Gene Expression and Activity
  64. Gene Amplification in a p53-Deficient Cell Line Requires Cell Cycle Progression under Conditions That Generate DNA Breakage
  65. 87 BCL-2 activation by ionizing radiation in a glioblastoma cell line
  66. Lack of functional retinoblastoma protein mediates increased resistance to antimetabolites in human sarcoma cell lines.
  67. Deficiency of retinoblastoma protein leads to inappropriate S-phase entry, activation of E2F-responsive genes, and apoptosis.
  68. Genetic instability as a consequence of inappropriate entry into and Progression through S-phase
  69. Chromosomal Localization of the Human Retinoid X Receptors
  70. Recombination by sequence repeats with formation of suppressive or residual mitochondrial DNA in Neurospora.
  71. Characterization of a novel plasmid-like element in Neurospora crassa derived mostly from the mitochondrial DNA
  72. Apoptosis Assays
  73. Caspase-3 Activation is a Critical Determinant of Genotoxic Stress-Induced Apoptosis
  74. Targeting Cyclins to Cause Cancer Cell Apoptosis
  75. Novel strategies for protecting mitochondria (the cellular powerhouse) against low-LET radiation: a review.