All Stories

  1. A machine learning model trained on a high-throughput antibacterial screen increases the hit rate of drug discovery

    Article • PLoS Computational Biology, October 2022, PLOS

    Dr Silvia T Cardona

  2. Competitive Fitness of Essential Gene Knockdowns Reveals a Broad-Spectrum Antibacterial Inhibitor of the Cell Division Protein FtsZ

    Article • Antimicrobial Agents and Chemotherapy, October 2018, ASM Journals

    Dr Silvia Buroni, Dr Silvia T Cardona

  3. Competitive Growth Enhances Conditional Growth Mutant Sensitivity to Antibiotics and Exposes a Two-Component System as an Emerging Antibacterial Target in Burkholderia cenocepacia

    Article • Antimicrobial Agents and Chemotherapy, October 2016, ASM Journals

    Dr Silvia T Cardona

  4. Draft Genome Sequences of Burkholderia contaminans FFI-28, a Strain Isolated from a Contaminated Pharmaceutical Solution

    Article • Genome Announcements, October 2016, ASM Journals

    Dr Silvia T Cardona

  5. An electron transfer flavoprotein is essential for viability and its depletion causes a rod-to-sphere change in Burkholderia cenocepacia

    Article • Microbiology, October 2015, Society for General Microbiology

    Dr Silvia T Cardona

  6. Draft Genome Sequences of Burkholderia contaminans , a Burkholderia cepacia Complex Species That Is Increasingly Recovered from Cystic Fibrosis Patients

    Article • Genome Announcements, August 2015, ASM Journals

    Dr Silvia T Cardona

  7. A Pipeline for Screening Small Molecules with Growth Inhibitory Activity against Burkholderia cenocepacia

    Article • PLoS ONE, June 2015, PLOS

    Dr Silvia T Cardona

  8. Chemical Inhibition of Bacterial Ribosome Biogenesis Shows Efficacy in a Worm Infection Model

    Article • Antimicrobial Agents and Chemotherapy, February 2015, ASM Journals

    Mr Jonathan M Stokes, Professor Eric D Brown, Dr Silvia T Cardona

  9. The attenuated virulence of aBurkholderia cenocepacia paaABCDEmutant is due to inhibition of quorum sensing by release of phenylacetic acid

    Article • Molecular Microbiology, September 2014, Wiley

    Dr Silvia T Cardona, Prof Brijesh Kumar

  10. Genomic tools to profile antibiotic mode of action

    Article • Critical Reviews in Microbiology, March 2014, Taylor & Francis

    Dr Silvia T Cardona

  11. B urkholderia cenocepacia conditional growth mutant library created by random promoter replacement of essential genes

    Article • MicrobiologyOpen, February 2013, Wiley

    Dr Silvia T Cardona

  12. Recombinant human DNase I decreases biofilm and increases antimicrobial susceptibility in staphylococci

    Article • The Journal of Antibiotics, December 2011, Springer Science + Business Media

    Dr Silvia T Cardona

  13. Phenylalanine induces Burkholderia cenocepacia phenylacetic acid catabolism through degradation to phenylacetyl-CoA in synthetic cystic fibrosis sputum medium

    Article • Microbial Pathogenesis, September 2011, Elsevier

    Dr Silvia T Cardona

  14. 3-Hydroxyphenylacetic Acid Induces the Burkholderia cenocepacia Phenylacetic Acid Degradation Pathway ? Toward Understanding the Contribution of Aromatic Catabolism to Pathogenesis

    Article • Frontiers in Cellular and Infection Microbiology, January 2011, Frontiers

    Dr Silvia T Cardona

  15. Regulation of phenylacetic acid degradation genes of Burkholderia cenocepacia K56-2

    Article • BMC Microbiology, January 2009, Springer Science + Business Media

    Dr Silvia T Cardona

  16. A Putative Gene Cluster for Aminoarabinose Biosynthesis Is Essential for Burkholderia cenocepacia Viability

    Article • Journal of Bacteriology, March 2007, ASM Journals

    Dr Silvia T Cardona

  17. Identification of Essential Operons with a Rhamnose-Inducible Promoter in Burkholderia cenocepacia

    Article • Applied and Environmental Microbiology, April 2006, ASM Journals

    Dr Silvia T Cardona

  18. A Quorum-Quenching Approach To Investigate the Conservation of Quorum-Sensing-Regulated Functions within the Burkholderia cepacia Complex

    Article • Applied and Environmental Microbiology, February 2006, ASM Journals

    Dr Silvia T Cardona

  19. An expression vector containing a rhamnose-inducible promoter provides tightly regulated gene expression in Burkholderia cenocepacia

    Article • Plasmid, November 2005, Elsevier

    Dr Silvia T Cardona

  20. Diverse pathogenicity ofBurkholderia cepaciacomplex strains in theCaenorhabditis eleganshost model

    Article • FEMS Microbiology Letters, September 2005, Oxford University Press (OUP)

    Professor Leo Eberl, Dr Silvia T Cardona

  21. Survival and persistence of opportunistic Burkholderia species in host cells

    Article • Current Opinion in Microbiology, February 2005, Elsevier

    Dr Silvia T Cardona

  22. The Exopolyphosphatase Gene from Sulfolobus solfataricus: Characterization of the First Gene Found To Be Involved in Polyphosphate Metabolism in Archaea

    Article • Applied and Environmental Microbiology, October 2002, ASM Journals

    Dr Silvia T Cardona, Dr Francisco P. Chavez

  23. The Glycogen-Bound Polyphosphate Kinase fromSulfolobus acidocaldarius Is Actually a Glycogen Synthase

    Article • Applied and Environmental Microbiology, October 2001, ASM Journals

    Dr Silvia T Cardona

  24. Thermal Stability of Invertase in Reduced-Moisture Amorphous Matrices in Relation to Glassy State and Trehalose Crystallization

    Article • Journal of Food Science, January 1997, Wiley

    Dr Silvia T Cardona