All Stories

  1. Chloro-s-triazines-toxicokinetic, Toxicodynamic, Human Exposure, and Regulatory Considerations

    Article • Current Drug Metabolism, July 2021, Bentham Science Publishers

    Professor Olavi Pelkonen

  2. Cytochrome P450 Induction and Xeno-Sensing Receptors Pregnane X Receptor, Constitutive Androstane Receptor, Aryl Hydrocarbon Receptor and Peroxisome Proliferator-Activated Receptor α at the Crossroads of Toxicokinetics and Toxicodynamics

    Article • Basic & Clinical Pharmacology & Toxicology, April 2018, Wiley

    Professor Olavi Pelkonen

  3. TTC and herbal preparations

    Article • Toxicology Letters, September 2016, Elsevier

    Professor Olavi Pelkonen

  4. Cardiac safety of ophthalmic timolol

    Article • Expert Opinion on Drug Safety, August 2016, Taylor & Francis

    Jukka Mäenpää, Professor Olavi Pelkonen

  5. Drug Metabolism - FromIn VitrotoIn Vivo, From Simple to Complex

    Article • Basic & Clinical Pharmacology & Toxicology, July 2015, Wiley

    Professor Olavi Pelkonen

  6. Reactive Metabolites in Early Drug Development: Predictive In vitro Tools

    Article • Current Medicinal Chemistry, December 2014, Bentham Science Publishers

    Professor Olavi Pelkonen

  7. Differentiation-Promoting Medium Additives for Hepatocyte Cultivation and Cryopreservation

    Article • November 2014, Springer Science + Business Media

    Professor Olavi Pelkonen

  8. Human variation and CYP enzyme contribution in benfuracarb metabolism in human in vitro hepatic models

    Article • Toxicology Letters, January 2014, Elsevier

    Professor Olavi Pelkonen

  9. Metabolism of α-thujone in human hepatic preparationsin vitro

    Article • Xenobiotica, November 2010, Informa Healthcare

    Professor Olavi Pelkonen

  10. Chapter 5. The CYP2A Subfamily

    Article • January 2008, Royal Society of Chemistry

    Professor Olavi Pelkonen

  11. In Vitro Metabolism in Preclinical Drug Development

    Article • August 2007, Wiley

    Professor Olavi Pelkonen

  12. In vitro metabolism and interactions of the fungicide metalaxyl in human liver preparations

    Article • Environmental Toxicology and Pharmacology, January 2007, Elsevier

    Professor Olavi Pelkonen

  13. The Functional Role of CYP2B6 in Human Drug Metabolism: Substrates and Inhibitors In Vitro, In Vivo and In Silico

    Article • Current Drug Metabolism, October 2006, Bentham Science Publishers

    Professor Olavi Pelkonen

  14. Placental Toxicity of Organophosphate and Carbamate Pesticides

    Article • January 2006, Elsevier

    Professor Olavi Pelkonen

  15. Regulation of CYP3A genes in the human respiratory tract

    Article • Chemico-Biological Interactions, January 2005, Elsevier

    Professor Olavi Pelkonen

  16. Expression of CYP3A4 in human breast tumour and non-tumour tissues

    Article • Cancer Letters, December 2003, Elsevier

    Professor Olavi Pelkonen

  17. Dual action of oestrogens on the mouse constitutive androstane receptor

    Article • Biochemical Journal, December 2003, Portland Press Ltd.

    Professor Olavi Pelkonen

  18. Lack of association between CYP2A5 induction and apoptosis in mouse primary hepatocytes

    Article • Biochemical Pharmacology, February 2002, Elsevier

    Professor Olavi Pelkonen

  19. CYP2A6: a human coumarin 7-hydroxylase

    Article • Toxicology, April 2000, Elsevier

    Professor Olavi Pelkonen

  20. Metabolic Activation of Toxins: Tissue-Specific Expression and Metabolism in Target Organs

    Article • Environmental Health Perspectives, June 1997, JSTOR

    Professor Olavi Pelkonen

  21. Metabolic interactions of methoxsalen and coumarin in humans and mice

    Article • Biochemical Pharmacology, October 1994, Elsevier

    Professor Olavi Pelkonen

  22. Cytochrome P450 isoforms in human fetal tissues related to phenobarbital-inducible forms in the mouse

    Article • Biochemical Pharmacology, February 1993, Elsevier

    Professor Olavi Pelkonen

  23. Comparative studies on coumarin and testosterone metabolism in mouse and human livers

    Article • Biochemical Pharmacology, August 1991, Elsevier

    Professor Olavi Pelkonen

  24. Neonatal pharmacology

    Article • Current Opinion in Pediatrics, April 1990, Wolters Kluwer Health

    Professor Olavi Pelkonen

  25. Environmental factors of enzyme induction and inhibition

    Article • Pharmacology & Therapeutics, January 1987, Elsevier

    Professor Olavi Pelkonen

  26. Effect of five structurally diverse H2-receptor antagonists on drug metabolism

    Article • Biochemical Pharmacology, December 1986, Elsevier

    Professor Olavi Pelkonen

  27. Enzymology and regulation of xenobiotic and steroid metabolism in placenta

    Article • Biochemical Society Transactions, February 1984, Portland Press Ltd.

    Professor Olavi Pelkonen

  28. Cigarette smoking and drug metabolism

    Article • Clinical Pharmacology & Therapeutics, March 1983, Nature

    Professor Olavi Pelkonen

  29. Drug metabolism in alcoholics

    Article • Pharmacology & Therapeutics, January 1982, Elsevier

    Professor Olavi Pelkonen

  30. Biotransformation of xenobiotics in the fetus

    Article • Pharmacology & Therapeutics, January 1980, Elsevier

    Professor Olavi Pelkonen

  31. Drug metabolism in human fetal tissues

    Article • Life Sciences, November 1973, Elsevier

    Professor Olavi Pelkonen

  32. Drug metabolism and drug-induced spectral interactions in human fetal liver microsomes

    Article • Biochemical Pharmacology, October 1973, Elsevier

    Professor Olavi Pelkonen

  33. Host Variations in Carcinogen Metabolism and DNA Repair

    Article • Karger Publishers

    Professor Olavi Pelkonen