All Stories

  1. Recent advances in understanding the roles of whole genome duplications in evolution

    Article • F1000Research, August 2017, Faculty of 1000, Ltd.

    Carol MacKintosh

  2. GARNL1/RalGAPa1 mediates insulin-stimulated RalA activation and GLUT4 trafficking in muscle

    Article • Cellular Signalling, August 2014, Elsevier

    Carol MacKintosh

  3. Cancer mutations in 2R-gene families

    Article • Open Biology, May 2014, Royal Society Publishing

    Carol MacKintosh

  4. Effect of IRS4 Levels on PI 3-Kinase Signalling

    Article • PLoS ONE, September 2013, PLOS

    Carol MacKintosh

  5. AS160 deficiency causes whole-body insulin resistance via composite effects in multiple tissues

    Article • Biochemical Journal, January 2013, Portland Press Ltd.

    Carol MacKintosh

  6. Identification of the Amino Acids 300–600 of IRS-2 as 14-3-3 Binding Region with the Importance of IGF-1/Insulin-Regulated Phosphorylation of Ser-573

    Article • PLoS ONE, August 2012, PLOS

    Carol MacKintosh

  7. Human cell signalling networks

    Article • Open Biology, July 2012, Royal Society Publishing

    Carol MacKintosh

  8. The capture of phosphoproteins by 14-3-3 proteins mediates actions of insulin

    Article • Trends in Endocrinology and Metabolism, November 2011, Elsevier

    Carol MacKintosh

  9. ERK/p90 RSK /14-3-3 signalling has an impact on expression of PEA3 Ets transcription factors via the transcriptional repressor capicúa

    Article • Biochemical Journal, February 2011, Portland Press Ltd.

    Carol MacKintosh

  10. Mice with AS160/TBC1D4-Thr649Ala Knockin Mutation Are Glucose Intolerant with Reduced Insulin Sensitivity and Altered GLUT4 Trafficking

    Article • Cell Metabolism, January 2011, Elsevier

    Carol MacKintosh

  11. Mechanism of Activation of PKB/Akt by the Protein Phosphatase Inhibitor Calyculin A

    Article • Cell Biochemistry and Biophysics, August 2010, Springer Science + Business Media

    Carol MacKintosh

  12. Bioinformatic and experimental survey of 14-3-3-binding sites

    Article • Biochemical Journal, April 2010, Portland Press Ltd.

    Carol MacKintosh

  13. Naturally Occurring Inhibitors of Protein Serine/Threonine Phosphatases

    Article • January 2010, Elsevier

    Carol MacKintosh

  14. Differential regulation of NHE1 phosphorylation and glucose uptake by inhibitors of the ERK pathway and p90RSK in 3T3-L1 adipocytes

    Article • Cellular Signalling, December 2009, Elsevier

    Carol MacKintosh

  15. 14‐3‐3 Binding to Pim‐phosphorylated Ser166 and Ser186 of human Mdm2 – Potential interplay with the PKB/Akt pathway and p14ARF

    Article • FEBS Letters, January 2009, Wiley

    Carol MacKintosh

  16. Complementary regulation of TBC1D1 and AS160 by growth factors, insulin and AMPK activators

    Article • Biochemical Journal, January 2008, Portland Press Ltd.

    Carol MacKintosh

  17. Regulation of multisite phosphorylation and 14-3-3 binding of AS160 in response to IGF-1, EGF, PMA and AICAR

    Article • Biochemical Journal, October 2007, Portland Press Ltd.

    Carol MacKintosh

  18. Proteomic screen in the simple metazoan Hydra identifies 14-3-3 binding proteins implicated in cellular metabolism, cytoskeletal organisation and Ca2+ signalling

    Article • BMC Cell Biology, July 2007, Springer Science + Business Media

    Carol MacKintosh

  19. Phosphorylation and 14‐3‐3 binding of Arabidopsis trehalose‐phosphate synthase  5 in response to 2‐deoxyglucose

    Article • The Plant Journal, June 2006, Wiley

    Carol MacKintosh

  20. Chromatography: from colour writing to separation science

    Article • Biochemical Journal, January 2006, Portland Press Ltd.

    Carol MacKintosh

  21. Phosphodiesterase 3A binds to 14-3-3 proteins in response to PMA-induced phosphorylation of Ser 428

    Article • Biochemical Journal, November 2005, Portland Press Ltd.

    Carol MacKintosh

  22. Dynamic interactions between 14-3-3 proteins and phosphoproteins regulate diverse cellular processes

    Article • Biochemical Journal, July 2004, Portland Press Ltd.

    Carol MacKintosh

  23. 14-3-3-affinity purification of over 200 human phosphoproteins reveals new links to regulation of cellular metabolism, proliferation and trafficking

    Article • Biochemical Journal, April 2004, Portland Press Ltd.

    Carol MacKintosh

  24. Phosphorylation and 14‐3‐3 binding of Arabidopsis 6‐phosphofructo‐2‐kinase/fructose‐2,6‐bisphosphatase

    Article • The Plant Journal, January 2004, Wiley

    Carol MacKintosh

  25. Purification of a plant nucleotide pyrophosphatase as a protein that interferes with nitrate reductase and glutamine synthetase assays

    Article • European Journal of Biochemistry, March 2003, Wiley

    Carol MacKintosh, Dr Dave Bridges, Dave Bridges

  26. Naturally Occurring Inhibitors of Protein Serine/Threonine Phosphatases

    Article • January 2003, Elsevier

    Carol MacKintosh

  27. Do 14‐3‐3s regulate‘Resource Allocation in Crops’?

    Article • Annals of Applied Biology, February 2001, Wiley

    Carol MacKintosh

  28. Cytosolic glutamine synthetase and not nitrate reductase from the green alga Chlamydomonas reinhardtii is phosphorylated and binds 14-3-3 proteins

    Article • Planta, January 2001, Springer Science + Business Media

    Carol MacKintosh

  29. Microcystin affinity purification of plant protein phosphatases: PP1C, PP5 and a regulatory A‐subunit of PP2A

    Article • FEBS Letters, September 1999, Wiley

    Carol MacKintosh

  30. Phosphorylation‐dependent interactions between enzymes of plant metabolism and 14‐3‐3 proteins

    Article • The Plant Journal, April 1999, Wiley

    Carol MacKintosh

  31. Purification of a nitrate reductase kinase from Spinacea oleracea leaves, and its identification as a calmodulin-domain protein kinase

    Article • Planta, August 1998, Springer Science + Business Media

    Carol MacKintosh

  32. Regulation of cytosolic enzymes in primary metabolism by reversible protein phosphorylation

    Article • Current Opinion in Plant Biology, June 1998, Elsevier

    Carol MacKintosh

  33. Regulation of plant nitrate assimilation: from ecophysiology to brain proteins

    Article • New Phytologist, May 1998, Wiley

    Carol MacKintosh

  34. Further evidence that inhibitor‐2 acts like a chaperone to fold PP1 into its native conformation

    Article • FEBS Letters, November 1996, Wiley

    Carol MacKintosh

  35. Phosphorylated nitrate reductase from spinach leaves is inhibited by 14-3-3 proteins and activated by fusicoccin

    Article • Current Biology, September 1996, Elsevier

    Carol MacKintosh

  36. Identification of a regulatory phosphorylation site in the hinge 1 region of nitrate reductase from spinach (Spinacea oleracea) leaves

    Article • FEBS Letters, December 1995, Wiley

    Carol MacKintosh

  37. The cyanobacterial toxin microcystin binds covalently to cysteine‐273 on protein phosphatase 1

    Article • FEBS Letters, September 1995, Wiley

    Carol MacKintosh

  38. Protein histidine phosphatase activity in rat liver and spinach leaves

    Article • FEBS Letters, May 1995, Wiley

    Carol MacKintosh

  39. Purification of the hepatic glycogen‐associated form of protein phosphatase‐1 by microcystin‐Sepharose affinity chromatography

    Article • FEBS Letters, April 1995, Wiley

    Carol MacKintosh

  40. Purification of type 1 protein (serine/threonine) phosphatases by microcystin‐Sepharose affinity chromatography

    Article • FEBS Letters, December 1994, Wiley

    Carol MacKintosh

  41. Inhibitors of protein kinases and phosphatases

    Article • Trends in Biochemical Sciences, November 1994, Elsevier

    Carol MacKintosh

  42. Protein phosphatase inhibitors activate anti‐fungal defence responses of soybean cotyledons and cell cultures

    Article • The Plant Journal, January 1994, Wiley

    Carol MacKintosh

  43. The Inhibition of Protein Phosphatases by Toxins: Implications for Health and an Extremely Sensitive and Rapid Bioassay for Toxin Detection

    Article • January 1994, Elsevier

    Carol MacKintosh

  44. Protein phosphatase 2A and its [3H]cantharidin/[3H]endothall thioanhydride binding site

    Article • Biochemical Pharmacology, October 1993, Elsevier

    Carol MacKintosh

  45. A myofibrillar protein phosphatase from rabbit skeletal muscle contains the β isoform of protein phosphatase‐1 complexed to a regulatory subunit which greatly enhances the dephosphorylation of myosin

    Article • European Journal of Biochemistry, December 1992, Wiley

    Carol MacKintosh

  46. Regulation of spinach-leaf nitrate reductase by reversible phosphorylation

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, October 1992, Elsevier

    Carol MacKintosh

  47. Characterization of the major phosphofructokinase — dephosphorylating protein phosphatases from Ascaris suum muscle

    Article • Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, July 1992, Elsevier

    Carol MacKintosh

  48. Illumination increases the phosphorylation state of maize leaf phospho enolpyruvate car☐ylase by causing an increase in the activity of a protein kinase

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, July 1991, Elsevier

    Carol MacKintosh

  49. Tautomycin from the bacterium Streptomyces verticillatus

    Article • FEBS Letters, December 1990, Wiley

    Carol MacKintosh

  50. Sucrose‐phosphate synthase is dephosphorylated by protein phosphatase 2A in spinach leaves

    Article • FEBS Letters, September 1990, Wiley

    Carol MacKintosh

  51. Cyanobacterial microcystin‐LR is a potent and specific inhibitor of protein phosphatases 1 and 2A from both mammals and higher plants

    Article • FEBS Letters, May 1990, Wiley

    Carol MacKintosh

  52. Phosphorylation of the glycogen‐binding subunit of protein phosphatase‐1G in response to adrenalin

    Article • FEBS Letters, July 1988, Wiley

    Carol MacKintosh

  53. Affinity Methods for Phosphorylation-Dependent Interactions

    Article • Springer Science + Business Media

    Carol MacKintosh

  54. Synthesis and Use of the Protein Phosphatase Affinity Matrices Microcystin-Sepharose and Microcystin-Biotin-Sepharose

    Article • Springer Science + Business Media

    Carol MacKintosh