All Stories

  1. Structure and kinase activity of bacterial cell cycle regulator CcrZ

    Article • PLoS Genetics, May 2022, PLOS

    Lyle Simmons

  2. DNA damage checkpoint activation affects peptidoglycan synthesis and late divisome components in Bacillus subtilis

    Article • Molecular Microbiology, June 2021, Wiley

    Lyle Simmons

  3. RnhP is a plasmid‐borne RNase HI that contributes to genome maintenance in the ancestral strain Bacillus subtilis NCIB 3610

    Article • Molecular Microbiology, September 2020, Wiley

    Lyle Simmons

  4. The roles of replication-transcription conflict in mutagenesis and evolution of genome organization

    Article • PLoS Genetics, August 2020, PLOS

    Professor Jue D Wang, Lyle Simmons

  5. A bacterial DNA repair pathway specific to a natural antibiotic

    Article • Molecular Microbiology, October 2018, Wiley

    Lyle Simmons

  6. DdcA antagonizes a bacterial DNA damage checkpoint

    Article • Molecular Microbiology, October 2018, Wiley

    Lyle Simmons

  7. Cryptic protein interactions regulate DNA replication initiation

    Article • Molecular Microbiology, October 2018, Wiley

    Lyle Simmons

  8. Sources of spontaneous mutagenesis in bacteria

    Article • Critical Reviews in Biochemistry and Molecular Biology, November 2017, Taylor & Francis

    Lyle Simmons, Professor Jue D Wang

  9. Substrate Specificity for Bacterial RNases HII and HIII Is Influenced by Metal Availability

    Article • Journal of Bacteriology, October 2017, ASM Journals

    Lyle Simmons

  10. Complete Genome Sequence of Undomesticated Bacillus subtilis Strain NCIB 3610

    Article • Genome Announcements, May 2017, ASM Journals

    Lyle Simmons

  11. MutS2 Promotes Homologous Recombination in Bacillus subtilis

    Article • Journal of Bacteriology, October 2016, ASM Journals

    Lyle Simmons

  12. Implementation and Data Analysis of Tn-seq, Whole-Genome Resequencing, and Single-Molecule Real-Time Sequencing for Bacterial Genetics

    Article • Journal of Bacteriology, September 2016, ASM Journals

    Lyle Simmons

  13. Bacterial Nonhomologous End Joining Requires Teamwork

    Article • Journal of Bacteriology, July 2014, ASM Journals

    Lyle Simmons

  14. RecO and RecR Are Necessary for RecA Loading in Response to DNA Damage and Replication Fork Stress

    Article • Journal of Bacteriology, June 2014, ASM Journals

    Lyle Simmons

  15. RecD2 Helicase Limits Replication Fork Stress in Bacillus subtilis

    Article • Journal of Bacteriology, January 2014, ASM Journals

    Lyle Simmons

  16. Finished genome sequence of Bacillus subtilis

    Article • Genome Announcements, December 2013, ASM Journals

    Lyle Simmons

  17. Trapping and visualizing intermediate steps in the mismatch repair pathway in vivo

    Article • Molecular Microbiology, September 2013, Wiley

    Lyle Simmons

  18. Protein Interactions in Genome Maintenance as Novel Antibacterial Targets

    Article • PLoS ONE, March 2013, PLOS

    Lyle Simmons

  19. In Vivo Visualization of Mismatch Repair in Bacillus Subtilis using Single-Molecule Fluorescence Microscopy

    Article • Biophysical Journal, January 2013, Elsevier

    Lyle Simmons

  20. DnaN clamp zones provide a platform for spatiotemporal coupling of mismatch detection to DNA replication

    Article • Molecular Microbiology, December 2012, Wiley

    Lyle Simmons

  21. Far Western Blotting as a Rapid and Efficient Method for Detecting Interactions Between DNA Replication and DNA Repair Proteins

    Article • January 2012, Springer Science + Business Media

    Lyle Simmons

  22. Mismatch repair causes the dynamic release of an essential DNA polymerase from the replication fork

    Article • Molecular Microbiology, September 2011, Wiley

    Lyle Simmons

  23. DNA Damage and Reactive Nitrogen Species are Barriers to Vibrio cholerae Colonization of the Infant Mouse Intestine

    Article • PLoS Pathogens, February 2011, PLOS

    Lyle Simmons

  24. Role of Escherichia coli YbeY, a highly conserved protein, in rRNA processing

    Article • Molecular Microbiology, September 2010, Wiley

    Lyle Simmons

  25. Structure of the Endonuclease Domain of MutL: Unlicensed to Cut

    Article • Molecular Cell, July 2010, Elsevier

    Lyle Simmons

  26. Imaging Mismatch Repair and Cellular Responses to DNA Damage in Bacillus subtilis

    Article • Journal of Visualized Experiments, February 2010, MyJove Corporation

    Lyle Simmons

  27. Hydroxyurea Induces Hydroxyl Radical-Mediated Cell Death in Escherichia coli

    Article • Molecular Cell, December 2009, Elsevier

    Lyle Simmons

  28. Sinorhizobium meliloti CpdR1 is critical for co‐ordinating cell cycle progression and the symbiotic chronic infection

    Article • Molecular Microbiology, August 2009, Wiley

    Lyle Simmons

  29. The SOS Regulatory Network

    Article • EcoSal Plus, September 2008, ASM Journals

    Lyle Simmons

  30. β Clamp Directs Localization of Mismatch Repair in Bacillus subtilis

    Article • Molecular Cell, February 2008, Elsevier

    Lyle Simmons

  31. Multiple Ku orthologues mediate DNA non‐homologous end‐joining in the free‐living form and during chronic infection of Sinorhizobium meliloti

    Article • Molecular Microbiology, December 2007, Wiley

    Lyle Simmons

  32. Y-family DNA polymerases respond to DNA damage-independent inhibition of replication fork progression

    Article • The EMBO Journal, February 2006, Springer Science + Business Media

    Lyle Simmons

  33. Hyperinitiation of DNA replication in Escherichia coli leads to replication fork collapse and inviability

    Article • Molecular Microbiology, January 2004, Wiley

    Lyle Simmons

  34. DnaA Protein of Escherichia coli: oligomerization at the E. coli chromosomal origin is required for initiation and involves specific N‐terminal amino acids

    Article • Molecular Microbiology, August 2003, Wiley

    Lyle Simmons

  35. The dnaAcos allele of Escherichia coli: hyperactive initiation is caused by substitution of A184V and Y271H, resulting in defective ATP binding and aberrant DNA replication control

    Article • Molecular Microbiology, January 2003, Wiley

    Lyle Simmons