All Stories

  1. Endogenous Two-Photon Fluorescence Imaging Elucidates Metabolic Changes Related to Enhanced Glycolysis and Glutamine Consumption in Precancerous Epithelial Tissues

    Article • Cancer Research, May 2014, American Association for Cancer Research (AACR)

    Karl Munger

  2. Human Viral Oncogenesis: A Cancer Hallmarks Analysis

    Article • Cell Host & Microbe, March 2014, Elsevier

    Karl Munger

  3. Are Selective Estrogen Receptor Modulators (SERMs) a Therapeutic Option for HPV-Associated Cervical Lesions and Cancers?

    Article • American Journal Of Pathology, February 2014, Elsevier

    Karl Munger

  4. The LKB1 tumor suppressor differentially affects anchorage independent growth of HPV positive cervical cancer cell lines

    Article • Virology, November 2013, Elsevier

    Karl Munger

  5. Human papillomavirus type 16 E7 oncoprotein inhibits the anaphase promoting complex/cyclosome activity by dysregulating EMI1 expression in mitosis

    Article • Virology, November 2013, Elsevier

    Karl Munger

  6. The papillomavirus E7 proteins

    Article • Virology, October 2013, Elsevier

    Karl Munger

  7. Tumor suppressor p16 INK4A is necessary for survival of cervical carcinoma cell lines

    Article • Proceedings of the National Academy of Sciences, September 2013, Proceedings of the National Academy of Sciences

    Karl Munger

  8. Biochemical and Functional Interactions of Human Papillomavirus Proteins with Polycomb Group Proteins

    Article • Viruses, May 2013, MDPI AG

    Karl Munger

  9. The HPV16 E6 Oncoprotein Causes Prolonged Receptor Protein Tyrosine Kinase Signaling and Enhances Internalization of Phosphorylated Receptor Species

    Article • PLoS Pathogens, March 2013, PLOS

    Karl Munger

  10. The Human Papillomavirus Type 8 E6 Protein Interferes with NOTCH Activation during Keratinocyte Differentiation

    Article • Journal of Virology, January 2013, ASM Journals

    Karl Munger

  11. Human papillomavirus type 16 E7 oncoprotein engages but does not abrogate the mitotic spindle assembly checkpoint

    Article • Virology, October 2012, Elsevier

    Karl Munger

  12. Cancer associated human papillomaviruses

    Article • Current Opinion in Virology, August 2012, Elsevier

    Karl Munger

  13. Viral Perturbations of Host Networks Reflect Disease Etiology

    Article • PLoS Computational Biology, June 2012, PLOS

    Karl Munger

  14. Modulation of Autophagy-Like Processes by Tumor Viruses

    Article • Cells, June 2012, MDPI AG

    Karl Munger

  15. A discrete population of squamocolumnar junction cells implicated in the pathogenesis of cervical cancer

    Article • Proceedings of the National Academy of Sciences, June 2012, Proceedings of the National Academy of Sciences

    Karl Munger

  16. Systematic identification of interactions between host cell proteins and E7 oncoproteins from diverse human papillomaviruses

    Article • Proceedings of the National Academy of Sciences, January 2012, Proceedings of the National Academy of Sciences

    Karl Munger

  17. Elucidating metabolic, subcellular, and tissue-level changes induced by HPV-related oncoproteins

    Article • January 2012, Optical Society of America (OSA)

    Karl Munger

  18. Automated Biochemical, Morphological, and Organizational Assessment of Precancerous Changes from Endogenous Two-Photon Fluorescence Images

    Article • PLoS ONE, September 2011, PLOS

    Karl Munger

  19. Human papillomavirus E7 oncoprotein induces KDM6A and KDM6B histone demethylase expression and causes epigenetic reprogramming

    Article • Proceedings of the National Academy of Sciences, January 2011, Proceedings of the National Academy of Sciences

    Karl Munger

  20. Prognostic Implications of HPV in Oropharyngeal Cancer

    Article • New England Journal of Medicine, July 2010, New England Journal of Medicine (NEJM/MMS)

    Karl Munger

  21. Kinase requirements in human cells: V. Synthetic lethal interactions between p53 and the protein kinases SGK2 and PAK3

    Article • Proceedings of the National Academy of Sciences, June 2010, Proceedings of the National Academy of Sciences

    Karl Munger

  22. Molecular Basis of Gynecologic Diseases

    Article • January 2010, Elsevier

    Karl Munger

  23. Human Papillomaviruses and Associated Malignancies

    Article • December 2009, World Scientific Pub Co Pte Lt

    Karl Munger

  24. Oncogenic activities of human papillomaviruses

    Article • Virus Research, August 2009, Elsevier

    Karl Munger

  25. HPV16 E7 oncogene expression in normal human epithelial cells causes molecular changes indicative of an epithelial to mesenchymal transition

    Article • Virology, August 2009, Elsevier

    Karl Munger

  26. Expression of a viral oncoprotein in normal human epithelial cells triggers an autophagy-related process: Is autophagy an “Achilles’ heel” of human cancers?

    Article • Autophagy, May 2009, Taylor & Francis

    Karl Munger

  27. Expression of the human papillomavirus type 16 E7 oncoprotein induces an autophagy-related process and sensitizes normal human keratinocytes to cell death in response to growth factor deprivation

    Article • Virology, March 2009, Elsevier

    Karl Munger

  28. The human papillomavirus E7 oncoprotein

    Article • Virology, February 2009, Elsevier

    Karl Munger

  29. Delocalization of the Microtubule Motor Dynein from Mitotic Spindles by the Human Papillomavirus E7 Oncoprotein Is Not Sufficient for Induction of Multipolar Mitoses

    Article • Cancer Research, October 2008, American Association for Cancer Research (AACR)

    Karl Munger

  30. Kinase requirements in human cells: I. Comparing kinase requirements across various cell types

    Article • Proceedings of the National Academy of Sciences, October 2008, Proceedings of the National Academy of Sciences

    Karl Munger

  31. Kinase requirements in human cells: II. Genetic interaction screens identify kinase requirements following HPV16 E7 expression in cancer cells

    Article • Proceedings of the National Academy of Sciences, October 2008, Proceedings of the National Academy of Sciences

    Karl Munger

  32. Direct association of the HPV16 E7 oncoprotein with cyclin A/CDK2 and cyclin E/CDK2 complexes

    Article • Virology, October 2008, Elsevier

    Karl Munger

  33. The Human Papillomavirus Type 8 E2 Gene Encodes a Transforming Activity Sufficient for Skin Tumor Formation in Transgenic Mice

    Article • Journal of Investigative Dermatology, September 2008, Elsevier

    Karl Munger

  34. Human Papillomavirus Type 16 E7 Oncoprotein Associates with E2F6

    Article • Journal of Virology, June 2008, ASM Journals

    Karl Munger

  35. Viruses associated with human cancer

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, March 2008, Elsevier

    Karl Munger

  36. Biochemical and Morphological Assessment of Normal and Pre-Cancerous Engineered Tissue Using Two-Photon Excited Autofluorescence

    Article • January 2008, Optical Society of America (OSA)

    Karl Munger

  37. Endogenous optical biomarkers of normal and human papillomavirus immortalized epithelial cells

    Article • International Journal of Cancer, November 2007, Wiley

    Karl Munger

  38. Diagnostic cellular organization features extracted from autofluorescence images

    Article • Optics Letters, November 2007, Optical Society of America (OSA)

    Karl Munger

  39. Ring-Opening and Ring-Closing Reactions of a Shikimic Acid-Derived Substrate Leading to Diverse Small Molecules

    Article • Journal of Combinatorial Chemistry, January 2007, American Chemical Society (ACS)

    Karl Munger

  40. Human Papillomavirus E6 and E7 Oncogenes

    Article • January 2007, Springer Science + Business Media

    Karl Munger

  41. American Idol and NIH Grant Review—Redux

    Article • Cell, November 2006, Elsevier

    Karl Munger

  42. Oncogenes

    Article • September 2006, Wiley

    Karl Munger

  43. Increased In Vitro Lifespan of Primary Human Keratinocytes Correlates with Decreased Migration

    Article • Journal of Investigative Dermatology, May 2006, Elsevier

    Karl Munger

  44. Intrinsic fluorescence changes associated with apoptosis of human epithelial keratinocytes

    Article • Gynecologic Oncology, December 2005, Elsevier

    Karl Munger

  45. Bovine papillomavirus E7 transformation function correlates with cellular p600 protein binding

    Article • Proceedings of the National Academy of Sciences, August 2005, Proceedings of the National Academy of Sciences

    Karl Munger

  46. Association of the human papillomavirus type 16 E7 oncoprotein with the 600-kDa retinoblastoma protein-associated factor, p600

    Article • Proceedings of the National Academy of Sciences, August 2005, Proceedings of the National Academy of Sciences

    Karl Munger

  47. Long-Term Maintenance of Human Keratinocytes In Vitro

    Article • Journal of Investigative Dermatology, February 2005, Elsevier

    Karl Munger

  48. Cyclin-dependent kinase inhibitor indirubin-3′-oxime selectively inhibits human papillomavirus type 16 E7-induced numerical centrosome anomalies

    Article • Oncogene, September 2004, Springer Science + Business Media

    Karl Munger

  49. Human Papillomavirus Infection and Centrosome Anomalies in Cervical Cancer

    Article • July 2004, Wiley

    Karl Munger

  50. Depletion of physiological levels of the human TID1 protein renders cancer cell lines resistant to apoptosis mediated by multiple exogenous stimuli

    Article • Oncogene, May 2004, Springer Science + Business Media

    Karl Munger

  51. Make WARTS, not cancer!

    Article • Oncogene, May 2004, Springer Science + Business Media

    Karl Munger

  52. The helix–loop–helix protein ID1 localizes to centrosomes and rapidly induces abnormal centrosome numbers

    Article • Oncogene, February 2004, Springer Science + Business Media

    Karl Munger

  53. Molecular pathways executing the “trophic sentinel” response in HPV-16 E7-expressing normal human diploid fibroblasts upon growth factor deprivation

    Article • Virology, February 2004, Elsevier

    Karl Munger

  54. Spectroscopic diagnosis and imaging of invisible pre-cancer

    Article • Faraday Discussions, January 2004, Royal Society of Chemistry

    Karl Munger

  55. TID1, a mammalian homologue of the drosophila tumor suppressor lethal(2) tumorous imaginal discs, regulates activation-induced cell death in Th2 cells

    Article • Oncogene, July 2003, Springer Science + Business Media

    Karl Munger

  56. Centrosomes, Genomic Instability, and Cervical Carcinogenesis

    Article • Critical Reviews in Eukaryotic Gene Expression, January 2003, Begell House

    Karl Munger

  57. Human papillomavirus immortalization and transformation functions

    Article • Virus Research, November 2002, Elsevier

    Karl Munger

  58. Human papillomaviruses and centrosome duplication errors: modeling the origins of genomic instability

    Article • Oncogene, September 2002, Springer Science + Business Media

    Karl Munger

  59. Stabilization and Functional Impairment of the Tumor Suppressor p53 by the Human Papillomavirus Type 16 E7 Oncoprotein

    Article • Virology, March 2002, Elsevier

    Karl Munger

  60. Aberrations in the MTS1 tumor suppressor locus in oral squamous cell carcinoma lines preferentially affect the INK4A gene and result in increased cdk6 activity

    Article • Oral Oncology, February 2002, Elsevier

    Karl Munger

  61. Papillomaviruses

    Article • January 2002, Elsevier

    Karl Munger

  62. The role of human papillomaviruses in human cancers

    Article • Frontiers in Bioscience, January 2002, Frontiers in Bioscience

    Karl Munger

  63. Disruption of Oncogene/Tumor Suppressor Networks During Human Carcinogenesis

    Article • Cancer Investigation, January 2002, Taylor & Francis

    Karl Munger

  64. Biological activities and molecular targets of the human papillomavirus E7 oncoprotein

    Article • Oncogene, November 2001, Springer Science + Business Media

    Karl Munger

  65. Ki-67, Cyclin E, and p16 INK4 Are Complimentary Surrogate Biomarkers for Human Papilloma Virus-Related Cervical Neoplasia

    Article • The American Journal of Surgical Pathology, July 2001, Wolters Kluwer Health

    Karl Munger

  66. The HPV E7 oncoprotein inhibits tumor necrosis factor α-mediated apoptosis in normal human fibroblasts

    Article • Oncogene, June 2001, Springer Science + Business Media

    Karl Munger

  67. Participation of Survivin in mitotic and apoptotic activities of normal and tumor‐derived cells*

    Article • Journal of Cellular Biochemistry, January 2001, Wiley

    Karl Munger

  68. Centrosome abnormalities, genomic instability and carcinogenic progression

    Article • Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, January 2001, Elsevier

    Karl Munger

  69. Expression of the HPV E7 Oncoprotein Mimics but Does Not Evoke a p53-Dependent Cellular DNA Damage Response Pathway

    Article • Virology, June 1999, Elsevier

    Karl Munger

  70. Re-expression of endogenous p16ink4a in oral squamous cell carcinoma lines by 5-aza-2′-deoxycytidine treatment induces a senescence-like state

    Article • Oncogene, December 1998, Springer Science + Business Media

    Karl Munger

  71. A Novel Human DnaJ Protein, hTid-1, a Homolog of the Drosophila Tumor Suppressor Protein Tid56, Can Interact with the Human Papillomavirus Type 16 E7 Oncoprotein

    Article • Virology, July 1998, Elsevier

    Karl Munger

  72. The human papillomavirus-16 E6 oncoprotein decreases the vigilance of mitotic checkpoints

    Article • Oncogene, December 1997, Springer Science + Business Media

    Karl Munger

  73. Destabilization of the RB Tumor Suppressor Protein and Stabilization of p53 Contribute to HPV Type 16 E7-Induced Apoptosis

    Article • Virology, December 1997, Elsevier

    Karl Munger

  74. The carboxyl-terminal zinc-binding domain of the human papillomavirus E7 protein can be functionally replaced by the homologous sequences of the E6 protein

    Article • Virus Research, November 1997, Elsevier

    Karl Munger

  75. Interactions of the human papillomavirus E7 protein with cell cycle regulators

    Article • Seminars in Cancer Biology, December 1996, Elsevier

    Karl Munger

  76. Dimerization of the Human Papillomavirus E7 Oncoproteinin Vivo

    Article • Virology, December 1995, Elsevier

    Karl Munger

  77. The molecular biology of cervical cancer

    Article • Journal of Cellular Biochemistry, January 1995, Wiley

    Karl Munger

  78. A Mutational Analysis of the Amino Terminal Domain of the Human Papillomavirus Type 16 E7 Oncoprotein

    Article • Virology, December 1994, Elsevier

    Karl Munger

  79. Functions of Human Papillomavirus Proteins

    Article • January 1994, Springer Science + Business Media

    Karl Munger

  80. The human papillomavirus E7 protein as a transforming and transactivating factor

    Article • Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, May 1993, Elsevier

    Karl Munger

  81. Efficiency of binding the retinoblastoma protein correlates with the transforming capacity of the E7 oncoproteins of the human papillomaviruses.

    Article • Proceedings of the National Academy of Sciences, May 1992, Proceedings of the National Academy of Sciences

    Karl Munger

  82. Adenovirus E1A, simian virus 40 tumor antigen, and human papillomavirus E7 protein share the capacity to disrupt the interaction between transcription factor E2F and the retinoblastoma gene product.

    Article • Proceedings of the National Academy of Sciences, May 1992, Proceedings of the National Academy of Sciences

    Karl Munger

  83. Factor-binding element in the human c-myc promoter involved in transcriptional regulation by transforming growth factor beta 1 and by the retinoblastoma gene product.

    Article • Proceedings of the National Academy of Sciences, November 1991, Proceedings of the National Academy of Sciences

    Karl Munger

  84. The state of the p53 and retinoblastoma genes in human cervical carcinoma cell lines.

    Article • Proceedings of the National Academy of Sciences, July 1991, Proceedings of the National Academy of Sciences

    Karl Munger

  85. c-myc and pRB: Role in TGF- 1 Inhibition of Keratinocyte Proliferation

    Article • Cold Spring Harbor Symposia on Quantitative Biology, January 1991, Cold Spring Harbor Laboratory Press

    Karl Munger

  86. Oncoproteins Encoded by the Cancer-associated Human Papillomaviruses Target the Products of the Retinoblastoma and p53 Tumor Suppressor Genes

    Article • Cold Spring Harbor Symposia on Quantitative Biology, January 1991, Cold Spring Harbor Laboratory Press

    Karl Munger

  87. TGF-β1 inhibition of c-myc transcription and growth in keratinocytes is abrogated by viral transforming proteins with pRB binding domains

    Article • Cell, June 1990, Elsevier

    Karl Munger

  88. The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product

    Article • Science, February 1989, American Association for the Advancement of Science

    Karl Munger

  89. Functional and Sequence Similarities Between HPV16 E7 and Adenovirus E1A

    Article • January 1989, Springer Science + Business Media

    Karl Munger

  90. The human papillomavirus type 16 E7 gene encodes transactivation and transformation functions similar to those of adenovirus E1A

    Article • Cell, May 1988, Elsevier

    Karl Munger

  91. Peptide mapping of vertebrate and invertebrate metallothioneins

    Article • Inorganica Chimica Acta, January 1988, Elsevier

    Karl Munger

  92. Expression of the synthetic gene of an artificial DDT-binding polypeptide in Escherichia coli

    Article • Protein Engineering Design and Selection, January 1987, Oxford University Press (OUP)

    Karl Munger

  93. Isolation and Regulation of Expression of the Neurospora Crassa Copper Metallothionein Gene

    Article • January 1987, Springer Science + Business Media

    Karl Munger

  94. Luminescence Emission from the Cu(I)-Thiolate Complex in Metallothioneins

    Article • January 1987, Springer Science + Business Media

    Karl Munger

  95. Metal accumulation inAgaricus bisporus: Influence of Cd and Cu on growth and tyrosinase activity

    Article • Cellular and Molecular Life Sciences, September 1982, Springer Science + Business Media

    Karl Munger

  96. Viral carcinogenesis and genomic instability

    Article • Springer Science + Business Media

    Karl Munger