All Stories

  1. How Much Vitamin D is Too Much? A Case Report and Review of the Literature

    Article • Endocrine Metabolic & Immune Disorders - Drug Targets, September 2021, Bentham Science Publishers

    Professor Vincenzo - Rochira, Manuela Simoni

  2. Lessons Learned in Andrology: Back to the future: making children in bed (at the right time)

    Article • Andrology, April 2014, Wiley

    Manuela Simoni

  3. The PCOS evolutionary paradox: a GWAS-based, in silico, evolutionary explanation

    Article • Endocrine Abstracts, April 2014, Bioscientifica

    Manuela Simoni

  4. GH Deficiency in HIV-infected patients compared to hypopituitary patients

    Article • Endocrine Abstracts, April 2014, Bioscientifica

    Manuela Simoni

  5. The FSHR polymorphism p.N680S mediates different response kinetics to FSH in vitro

    Article • Endocrine Abstracts, April 2014, Bioscientifica

    Manuela Simoni

  6. Gonadal and sexual function in young/middle aged human immunodeficiency virus (HIV)-infected men

    Article • Endocrine Abstracts, April 2014, Bioscientifica

    Manuela Simoni

  7. TERT promoter mutations correlate with a more advanced stage at diagnosis and with a poorer prognosis in differentiated thyroid cancer

    Article • Endocrine Abstracts, April 2014, Bioscientifica

    Manuela Simoni

  8. Reassembly of somatic cells and testicular organogenesis in vitro

    Article • Tissue and Cell, February 2014, Elsevier

    Manuela Simoni

  9. Gene Polymorphisms in Female Reproduction

    Article • January 2014, Springer Science + Business Media

    Manuela Simoni

  10. MECHANISMS IN ENDOCRINOLOGY: Genetics of FSH action: a 2014-and-beyond view

    Article • November 2013, Bioscientifica

    Manuela Simoni

  11. Are pre-miR-146a and PTTG1 associated with papillary thyroid cancer?

    Article • October 2013, Bioscientifica

    Manuela Simoni

  12. The Diagnostic Value of Calcitonin Measurement in Wash-Out Fluid from Fine-Needle Aspiration of Thyroid Nodules in the Diagnosis of Medullary Thyroid Cancer

    Article • Endocrine Practice, September 2013, AACE Corp (American Association of Clinical Endocrinologists)

    Manuela Simoni, Professor Vincenzo - Rochira

  13. The prognostic value of miRNA146a in follicular thyroid carcinoma

    Article • Medical Oncology, August 2013, Springer Science + Business Media

    Manuela Simoni

  14. Effects of treatment for acromegaly on bone mineral density: is pegvisomant protective on lumbar BMD?

    Article • Endocrine Abstracts, April 2013, Bioscientifica

    Manuela Simoni

  15. Pre-miR146a expression profiling of follicular thyroid carcinoma

    Article • Endocrine Abstracts, April 2013, Bioscientifica

    Manuela Simoni

  16. Genotype and phenotype characterization of the cohort of Italian patients with idiopathic central hypogonadism (ICH)

    Article • Endocrine Abstracts, April 2013, Bioscientifica

    Manuela Simoni

  17. The combination of genetic variants in the FSHR and FSHB genes affect serum FSH in women of reproductive age

    Article • Endocrine Abstracts, April 2013, Bioscientifica

    Manuela Simoni, Dr manuela de carlo

  18. Association of pre-miR-146a rs2910164 GG genotype with papillary thyroid cancer: a new case--control study on two adjacent genes on chromosome 5, pre-miR-146a and PTTG1.

    Article • Endocrine Abstracts, April 2013, Bioscientifica

    Manuela Simoni

  19. Mutations and somatic changes in the genotype of rs2910164 in pre-miR146a are frequent in follicular thyroid carcinoma

    Article • Endocrine Abstracts, April 2013, Bioscientifica

    Manuela Simoni

  20. Complete aromatase deficiency in four adult men: detection of a novel mutation and two known mutations in theCYP19A1gene

    Article • Endocrine Abstracts, April 2013, Bioscientifica

    Manuela Simoni

  21. Polymorphisms in gonadotropin and gonadotropin receptor genes as markers of ovarian reserve and response in in vitro fertilization

    Article • Fertility and Sterility, March 2013, Elsevier

    Manuela Simoni

  22. Prevalence of Olfactory and Other Developmental Anomalies in Patients with Central Hypogonadotropic Hypogonadism

    Article • Frontiers in Endocrinology, January 2013, Frontiers

    Manuela Simoni, Professor Vincenzo - Rochira

  23. LH and hCG Action on the Same Receptor Results in Quantitatively and Qualitatively Different Intracellular Signalling

    Article • PLoS ONE, October 2012, PLOS

    Manuela Simoni

  24. Aromatase expression in human peripheral blood leucocytes (PBLs) and in various tissues in primates: studies in elderly humans and cynomolgus monkeys

    Article • Journal of Medical Primatology, September 2012, Wiley

    Manuela Simoni

  25. Effect of sphingosine 1-phosphate (S1P) receptor agonists FTY720 and CYM5442 on atherosclerosis development in LDL receptor deficient (LDL-R−/−) mice

    Article • Vascular Pharmacology, August 2012, Elsevier

    Manuela Simoni

  26. Methodology for measuring testosterone, dihydrotestosterone and sex hormone-binding globulin in a clinical setting

    Article • July 2012, Cambridge University Press

    Manuela Simoni

  27. Testosterone-Induced Prostate Growth Is Blocked by Co- and Preadministration of Norethisterone Enanthate in Castrated Cynomolgus Monkeys

    Article • Urologia Internationalis, January 2012, Karger Publishers

    Manuela Simoni

  28. Effects of polymorphisms in gonadotropin and gonadotropin receptor genes on reproductive function

    Article • Reviews in Endocrine and Metabolic Disorders, September 2011, Springer Science + Business Media

    Manuela Simoni

  29. Effects of the FSH receptor gene polymorphism p.N680S on cAMP and steroid production in cultured primary human granulosa cells

    Article • Reproductive BioMedicine Online, August 2011, Elsevier

    Manuela Simoni, Professor Martin Götte

  30. Copy Number Variants in Patients with Severe Oligozoospermia and Sertoli-Cell-Only Syndrome

    Article • PLoS ONE, April 2011, PLOS

    Manuela Simoni

  31. Pharmacogenetics of ovarian stimulation in the twenty-first century

    Article • March 2011, Cambridge University Press

    Manuela Simoni

  32. Genetic screening for infertility: When should it be done?

    Article • Middle East Fertility Society Journal, July 2010, Springer Science + Business Media

    Manuela Simoni

  33. Male 41, XXY* Mice as a Model for Klinefelter Syndrome: Hyperactivation of Leydig Cells

    Article • Endocrinology, June 2010, Endocrine Society

    Manuela Simoni

  34. Endocrine Laboratory Diagnosis

    Article • January 2010, Springer Science + Business Media

    Manuela Simoni

  35. Cytogenetic and Molecular Genetic Investigations

    Article • January 2010, Springer Science + Business Media

    Manuela Simoni

  36. Physiology of Testicular Function

    Article • January 2010, Springer Science + Business Media

    Manuela Simoni

  37. Diseases of the Hypothalamus and the Pituitary Gland

    Article • January 2010, Springer Science + Business Media

    Manuela Simoni

  38. Anti-Müllerian hormone in men with normal and reduced sperm concentration and men with maldescended testes

    Article • Fertility and Sterility, May 2009, Elsevier

    Manuela Simoni

  39. Endokrine Labordiagnostik

    Article • January 2009, Springer Science + Business Media

    Manuela Simoni

  40. Zytogenetische und molekulargenetische Untersuchungen

    Article • January 2009, Springer Science + Business Media

    Manuela Simoni

  41. Physiologie der Hodenfunktion

    Article • January 2009, Springer Science + Business Media

    Manuela Simoni

  42. Störungen im Bereich des Hypothalamus und der Hypophyse

    Article • January 2009, Springer Science + Business Media

    Manuela Simoni

  43. Impaired recognition memory in male mice with a supernumerary X chromosome

    Article • Physiology & Behavior, January 2009, Elsevier

    Manuela Simoni

  44. Follicle-stimulating hormone receptor and DAZL gene polymorphisms do not affect the age of menopause

    Article • Fertility and Sterility, December 2008, Elsevier

    Manuela Simoni

  45. Mutations in a Novel, Cryptic Exon of the Luteinizing Hormone/Chorionic Gonadotropin Receptor Gene Cause Male Pseudohermaphroditism

    Article • PLoS Medicine, April 2008, PLOS

    Manuela Simoni

  46. Complete Spermatogenesis in Orthotopic But Not in Ectopic Transplants of Autologously Grafted Marmoset Testicular Tissue

    Article • Endocrinology, April 2008, Endocrine Society

    Manuela Simoni

  47. Krüppel-like factor 4 is involved in functional differentiation of testicular Sertoli cells

    Article • Developmental Biology, March 2008, Elsevier

    Manuela Simoni

  48. Polymorphisms of the luteinizing hormone/chorionic gonadotropin receptor gene: association with maldescended testes and male infertility

    Article • Pharmacogenetics and Genomics, March 2008, Wolters Kluwer Health

    Manuela Simoni

  49. Clinical consequences of microdeletions of the Y chromosome: the extended Münster experience

    Article • Reproductive BioMedicine Online, January 2008, Elsevier

    Manuela Simoni

  50. LHR splicing variants and gene expression in the marmoset monkey

    Article • Molecular and Cellular Endocrinology, December 2007, Elsevier

    Manuela Simoni

  51. Chorionic Gonadotropin β-Subunit Gene Expression in the Marmoset Pituitary Is Controlled by Steroidogenic Factor 1, Early Growth Response Protein 1, and Pituitary Homeobox Factor 1

    Article • Endocrinology, December 2007, Endocrine Society

    Manuela Simoni

  52. Genomic Checkpoints for Exon 10 Usage in the Luteinizing Hormone Receptor Type 1 and Type 2

    Article • Molecular Endocrinology, August 2007, Endocrine Society

    Manuela Simoni

  53. Replacement of connexin43 by connexin26 in transgenic mice leads to dysfunctional reproductive organs and slowed ventricular conduction in the heart

    Article • BMC Developmental Biology, April 2007, Springer Science + Business Media

    Manuela Simoni

  54. Genetics of Hypogonadotropic Hypogonadism

    Article • Hormone Research in Paediatrics, January 2007, Karger Publishers

    Manuela Simoni

  55. Gene polymorphisms and male infertility – a meta-analysis and literature review

    Article • Reproductive BioMedicine Online, January 2007, Elsevier

    Manuela Simoni

  56. Elevated follicle-stimulating hormone levels and the chances for azoospermic men to become fathers after retrieval of elongated spermatids from cryopreserved testicular tissue

    Article • Fertility and Sterility, August 2006, Elsevier

    Manuela Simoni

  57. Hypothalamic and Gonadal Components of Hypogonadism in Boys with Prader-Labhart- Willi Syndrome

    Article • The Journal of Clinical Endocrinology & Metabolism, March 2006, Endocrine Society

    Manuela Simoni

  58. Endogenous Progesterone and the Exogenous Progestin Norethisterone Enanthate Are Associated with a Proinflammatory Profile in Healthy Men

    Article • The Journal of Clinical Endocrinology & Metabolism, December 2005, Endocrine Society

    Manuela Simoni, Professor Eberhard Nieschlag

  59. Genetic complexity of FSH receptor function

    Article • Trends in Endocrinology and Metabolism, October 2005, Elsevier

    Manuela Simoni

  60. Single-nucleotide polymorphisms in the promoter region influence the expression of the human follicle-stimulating hormone receptor

    Article • Fertility and Sterility, August 2005, Elsevier

    Manuela Simoni

  61. Pharmacokinetics and pharmacodynamics of injectable testosterone undecanoate in castrated cynomolgus monkeys (Macaca fascicularis) are independent of different oil vehicles

    Article • Journal of Medical Primatology, June 2005, Wiley

    Manuela Simoni

  62. Pharmacogenetics in ovarian stimulation – current concepts and future options

    Article • Reproductive BioMedicine Online, January 2005, Elsevier

    Manuela Simoni

  63. Serum adiponectin levels in hypogonadal males: influence of testosterone replacement therapy

    Article • Clinical Endocrinology, March 2004, Wiley

    Manuela Simoni

  64. Gene expression profiling of mouse Sertoli cell lines

    Article • Cell and Tissue Research, February 2004, Springer Science + Business Media

    Manuela Simoni, Professor Premendu Prakash Mathur

  65. Follicle-stimulating hormone receptor polymorphisms in women with normogonadotropic anovulatory infertility

    Article • Fertility and Sterility, October 2003, Elsevier

    Manuela Simoni

  66. Absence of Exon 10 of the Human Luteinizing Hormone (LH) Receptor Impairs LH, But Not Human Chorionic Gonadotropin Action

    Article • The Journal of Clinical Endocrinology & Metabolism, May 2003, Endocrine Society

    Manuela Simoni

  67. An Activated Human Follicle-Stimulating Hormone (FSH) Receptor Stimulates FSH-Like Activity in Gonadotropin-Deficient Transgenic Mice

    Article • Molecular Endocrinology, November 2002, Endocrine Society

    Manuela Simoni

  68. CAG repeat length in the androgen receptor gene and gonadotrophin suppression influence the effectiveness of hormonal male contraception

    Article • Clinical Endocrinology, October 2002, Wiley

    Manuela Simoni

  69. Association of basal follicle stimulating hormone (FSH) levels with FSH receptor variants in subfertile women with normal menstrual cycle: implications for ovarian sensitivity to FSH

    Article • Fertility and Sterility, September 2002, Elsevier

    Manuela Simoni

  70. Inverse Correlation between Sperm Concentration and Number of Androgen Receptor CAG Repeats in Normal Men1

    Article • The Journal of Clinical Endocrinology & Metabolism, June 2001, Endocrine Society

    Manuela Simoni

  71. Follicle-stimulating-hormone receptor and twinning

    Article • The Lancet, January 2001, Elsevier

    Manuela Simoni

  72. Ovarian Response to Follicle-Stimulating Hormone (FSH) Stimulation Depends on the FSH Receptor Genotype1

    Article • The Journal of Clinical Endocrinology & Metabolism, September 2000, Endocrine Society

    Manuela Simoni

  73. Male Hypogonadism Caused by Homozygous Deletion of Exon 10 of the Luteinizing Hormone (LH) Receptor: Differential Action of Human Chorionic Gonadotropin and LH

    Article • The Journal of Clinical Endocrinology & Metabolism, June 2000, Endocrine Society

    Manuela Simoni

  74. Repeated intramuscular injections of testosterone undecanoate for substitution therapy in hypogonadal men

    Article • Clinical Endocrinology, December 1999, Wiley

    Manuela Simoni

  75. Constitutively Active Mutations of G Protein-Coupled Receptors

    Article • Archives of Medical Research, November 1999, Elsevier

    Manuela Simoni

  76. Cloning and expression of cynomolgus monkey (Macaca fascicularis) gonadotropins luteinizing hormone and follicle-stimulating hormone and identification of two polymorphic sites in the luteinizing hormone β subunit

    Article • Molecular and Cellular Endocrinology, October 1999, Elsevier

    Manuela Simoni

  77. Clinical Trial of Transdermal Testosterone and Oral Levonorgestrel for Male Contraception1

    Article • The Journal of Clinical Endocrinology & Metabolism, April 1999, Endocrine Society

    Manuela Simoni

  78. Mutational Analysis of the Follicle-Stimulating Hormone (FSH) Receptor in Normal and Infertile Men: Identification and Characterization of Two Discrete FSH Receptor Isoforms1

    Article • The Journal of Clinical Endocrinology & Metabolism, February 1999, Endocrine Society

    Manuela Simoni

  79. The EAA International Quality Control Programme for Y‐Chromosomal Microdeletions

    Article • International Journal of Andrology, December 1998, Wiley

    Manuela Simoni

  80. Molecular Pathophysiology and Clinical Manifestations of Gonadotropin Receptor Defects

    Article • Steroids, May 1998, Elsevier

    Manuela Simoni

  81. A Mutation in the First Transmembrane Domain of the Lutropin Receptor Causes Male Precocious Puberty

    Article • The Journal of Clinical Endocrinology & Metabolism, February 1998, Endocrine Society

    Manuela Simoni

  82. The Follicle-Stimulating Hormone Receptor: Biochemistry, Molecular Biology, Physiology, and Pathophysiology1

    Article • Endocrine Reviews, December 1997, Endocrine Society

    Manuela Simoni

  83. Strong association between serum levels of leptin and testosterone in men

    Article • Clinical Endocrinology, August 1997, Wiley

    Manuela Simoni

  84. Effect of Testosterone and Estradiol in a Man with Aromatase Deficiency

    Article • New England Journal of Medicine, July 1997, New England Journal of Medicine (NEJM/MMS)

    Manuela Simoni

  85. Screening for deletions of the Y chromosome involving the DAZ (Deleted in AZoospermia) gene in azoospermia and severe oligozoospermia

    Article • Fertility and Sterility, March 1997, Elsevier

    Manuela Simoni

  86. Functional and clinical consequences of mutations in the FSH receptor

    Article • Molecular and Cellular Endocrinology, December 1996, Elsevier

    Manuela Simoni

  87. FSH in therapy: physiological basis, new preparations and clinical use

    Article • Reproductive Medicine Review, October 1995, Cambridge University Press

    Manuela Simoni

  88. In Vitro Sertoli Cell Bioassay of Follicle-Stimulating Hormone (FSH): Serum from Different Animal Species Alters the Morphology of Rat Sertoli Cells without Affecting Their Response to FSH

    Article • General and Comparative Endocrinology, July 1994, Elsevier

    Manuela Simoni

  89. Transgenic animals in male reproduction research

    Article • Experimental and Clinical Endocrinology & Diabetes, January 1994, Thieme Publishing Group

    Manuela Simoni

  90. Molecular heterogeneity of serum follicle‐stimulating hormone in hypogonadal patients before and during androgen replacement therapy and in normal men

    Article • Clinical Endocrinology, August 1993, Wiley

    Manuela Simoni

  91. Effects of antiandrogens and ethane dimethane sulphonate (EDS) on gene expression, free subunits, bioactivity and secretion of pituitary gonadotrophins in male rats

    Article • Molecular and Cellular Endocrinology, February 1993, Elsevier

    Manuela Simoni

  92. Serum Bioactive Follicle-Stimulating Hormone-Like Activity in Human Pregnancy Is a Methodological Artifact*

    Article • The Journal of Clinical Endocrinology & Metabolism, November 1991, Endocrine Society

    Manuela Simoni