All Stories

  1. An Insight to the Toxic Effect of Sulfamerazine on Porcine Pancreatic Amylase and Lactate Dehydrogenase Activity: An In Vitro Study
  2. Structures, antimicrobial activity, DNA interaction and molecular docking studies of sulfamethoxazolyl-azo-acetylacetone and its nickel(II) complex
  3. MAP2c prevents arachidonic acid-induced fibril formation of tau: Role of chaperone activity and phosphorylation
  4. Delineation of Current Development of Antimitotic Compounds Targeting Cytoskeletal Protein Tubulin and Microtubule in the Cancer Therapy
  5. Editorial (Thematic Issue: “An Overview on Proteins of Biomedical Importance in Targeted Therapy of Cancer, Duchenne Muscular Dystrophy and Protein Misfolding Associated Neuropathy: Structure Function Relationship, Mechanism of Action, Role of Small Mo...
  6. Cytotoxic biphenyl-4-carboxylic acid targets the tubulin–microtubule system and inhibits cellular migration in HeLa cells
  7. Production and characterization of thermostable alkaline protease ofBacillus subtilis(ATCC 6633) from optimized solid-state fermentation
  8. Nanomaterial Mediated Drug Delivery, Image-Guided Therapy and Multifaceted Theranostic Systems in Cancer
  9. Production and Partial Purification of Alpha Amylase fromBacillus subtilis(MTCC 121) Using Solid State Fermentation
  10. Optimization of Amylase Production fromB. amyloliquefaciens(MTCC 1270) Using Solid State Fermentation
  11. Discrimination of Ligands with Different Flexibilities Resulting from the Plasticity of the Binding Site in Tubulin
  12. Binding of Indanocine to the Colchicine Site on Tubulin Promotes Fluorescence, and Its Binding Parameters Resemble Those of the Colchicine Analogue AC †
  13. Anti-mitotic activity of colchicine and the structural basis for its interaction with tubulin
  14. Oxalone and Lactone Moieties of Podophyllotoxin Exhibit Properties of Both the B and C Rings of Colchicine in Its Binding with Tubulin †
  15. Biphasic Kinetics of the Colchicine−Tubulin Interaction: Role of Amino Acids Surrounding the A ring of Bound Colchicine Molecule†
  16. -NH-Dansyl Isocolchicine Exhibits a Significantly Improved Tubulin-Binding Affinity and Microtubule Inhibition in Comparison to Isocolchicine by Binding Tubulin through Its A and B Rings †
  17. The B-ring substituent at C-7 of colchicine and the α-C-terminus of tubulin communicate through the “tail-body” interaction
  18. MAP2 prevents protein aggregation and facilitates reactivation of unfolded enzymes. Implications for the chaperone-like activity of MAP2
  19. BisANS binding to tubulin: Isothermal titration calorimetry and the site-specific proteolysis reveal the GTP-induced structural stability of tubulin