All Stories

  1. Recent Advances in Structural Modification Strategies for Lead Optimization of Tyrosine Kinase Inhibitors to Explore Novel Anticancer Agents
  2. Aldehyde oxidase at the crossroad of metabolism and preclinical screening
  3. Characterization of the novel anti-TNF-α single-chain fragment antibodies using experimental and computational approaches
  4. Involvement of CD24 in Multiple Cancer Related Pathways Makes It an Interesting New Target for Cancer Therapy
  5. Identification of Novel Single-Domain Antibodies against FGF7 Using Phage Display Technology
  6. GPCRTOP v.1.0: One-Step Web Server for Both Predicting Helical Transmembrane Segments and Identifying G Protein-Coupled Receptors
  7. Identifying key interactions stabilizing DOF zinc finger–DNA complexes using in silico approaches
  8. A Simple and Rapid Method for Expression and Purification of Functional TNF-α Using GST Fusion System
  9. Applying random forest and subtractive fuzzy c-means clustering techniques for the development of a novel G protein-coupled receptor discrimination method using pseudo amino acid compositions
  10. Design, Synthesis and in vitro Cytotoxicity Evaluation of New 3',4'-bis (3,4,5-trisubstituted)-4'H-spiro[indene-2,5'-isoxazol]-1(3H)-one Derivatives as Promising Anticancer Agents
  11. GPCRTOP: A Novel G Protein-Coupled Receptor Topology Prediction Method Based on Hidden Markov Model Approach Using Viterbi Algorithm
  12. In VitroandIn SilicoStudies to Explore Structural Features of Flavonoids for Aldehyde Oxidase Inhibition
  13. Phage display as a technology delivering on the promise of peptide drug discovery
  14. Preparation and Characterization of Chitosan/β-cyclodextrin Nanoparticles Containing Plasmid DNA Encoding Interleukin-12
  15. Structure-based investigation of rat aldehyde oxidase inhibition by flavonoids
  16. Solution structure of a tethered Lmo2LIM2/Ldb1LIDcomplex
  17. Comparison of 4-chloro-2-nitrophenol adsorption on single-walled and multi-walled carbon nanotubes
  18. New 5-(nitroheteroaryl)-1,3,4-thiadiazols containing acyclic amines at C-2: synthesis and SAR study for their antileishmanial activity
  19. Synthesis and anti-leishmanial activity of 5-(5-nitrofuran-2-yl)-1,3,4-thiadiazol-2-amines containing N-[(1-benzyl-1H-1,2,3-triazol-4-yl)methyl] moieties
  20. Prevalence of bacteriocin activities and bacteriocin-encoding genes in enterococcal clinical isolates in Iran
  21. Removal of 4-chloro-2-nitrophenol occurring in drug and pesticide waste by adsorption onto nano-titanium dioxide
  22. Structural modelling and dynamics of proteins for insights into drug interactions
  23. Identification of New Peptide Ligands for Epidermal Growth Factor Receptor Using Phage Display and Computationally Modeling their Mode of Binding
  24. 2D and 3D Quantitative Structure Activity Relationship studies of Human Microsomal Epoxide Hydrolase Inhibitors
  25. Structural basis of simultaneous recruitment of the transcriptional regulators LMO2 and FOG1/ZFPM1 by the transcription factor GATA1
  26. Synthesis and antileishmanial activity of novel 5-(5-nitrofuran-2-y1)-1,3,4-thiadiazoles with piperazinyl-linked benzamidine substituents
  27. Naproxen–eudragit® RS100 nanoparticles: Preparation and physicochemical characterization
  28. Solution structure of LMO2(LIM2)-Ldb1(LID)
  29. 1H, 15N and 13C assignments of an intramolecular Lmo2-LIM2/Ldb1-LID complex
  30. Degradation of trace aqueous 4-chloro-2-nitrophenol occurring in pharmaceutical industrial wastewater by ozone
  31. Rhodopsin: Structure, signal transduction and oligomerisation
  32. Non-specific translocation of peptide-displaying bacteriophage particles across the gastrointestinal barrier
  33. Modelling the structures of G protein-coupled receptors aided by three-dimensional validation
  34. Molecular modeling of histamine H3 receptor and QSAR studies on arylbenzofuran derived H3 antagonists
  35. Prediction of rotational orientation of transmembrane helical segments of integral membrane proteins using new environment-based propensities for amino acids derived from structural analyses
  36. Kinetic Analysis of Chlorpropamide Dissolution from Solid Dispersions
  37. QSPR models for the prediction of apparent volume of distribution
  38. Presence of transient helical segments in the galanin-like peptide evident from 1H NMR, circular dichroism, and prediction studies
  39. Comparison of the transmembrane helices of bovine rhodopsin in the crystal structure and the C α template based on cryo-electron microscopy maps and sequence analysis of the G protein-coupled receptors
  40. Enhancement of Dissolution Rate and Anti-inflammatory Effects of Piroxicam Using Solvent Deposition Technique
  41. Modeling of the structural features of integral-membrane proteins reverse-environment prediction of integral membrane protein structure (REPIMPS)
  42. Solubility Prediction for Furosemide in Water-Cosolvent Mixtures Using the Minimum Number of Experiments
  43. Relationship between potency and boiling point of general anesthetics: a thermodynamic consideration
  44. Structural and Computational Approaches in Drug Design for G Protein-Coupled Receptors
  45. An Introduction to the Basic Concepts in QSAR-Aided Drug Design