All Stories

  1. The kinetics of E-selectin- and P-selectin-induced intermediate activation of integrin αLβ2 on neutrophils

    Article • Journal of Cell Science, September 2021, The Company of Biologists

    Dr Rodger P McEver

  2. Heightened activation of embryonic megakaryocytes causes aneurysms in the developing brain of mice lacking podoplanin

    Article • Blood, February 2021, American Society of Hematology

    Dr Rodger P McEver

  3. Neutrophils lacking ERM proteins polarize and crawl directionally but have decreased adhesion strength

    Article • Blood Advances, August 2020, American Society of Hematology

    Dr Rodger P McEver

  4. Th1 Cells Rolling on Selectins Trigger DAP12-Dependent Signals That Activate Integrin αLβ2

    Article • The Journal of Immunology, November 2019, The American Association of Immunologists

    Dr Rodger P McEver

  5. Endothelial signaling by neutrophil-released oncostatin M enhances P-selectin–dependent inflammation and thrombosis

    Article • Blood Advances, January 2019, American Society of Hematology

    Dr Rodger P McEver

  6. Cooperative PSGL-1 and CXCR2 signaling in neutrophils promotes deep vein thrombosis in mice

    Article • Blood, August 2018, American Society of Hematology

    Dr Rodger P McEver

  7. Selectins and chemokines use shared and distinct signals to activate β2 integrins in neutrophils

    Article • Blood Advances, March 2018, American Society of Hematology

    Dr Rodger P McEver

  8. Circulating soluble P-selectin must dimerize to promote inflammation and coagulation in mice

    Article • Blood, May 2017, American Society of Hematology

    Dr Rodger P McEver

  9. Glycan Bound to the Selectin Low Affinity State Engages Glu-88 to Stabilize the High Affinity State under Force

    Article • Journal of Biological Chemistry, December 2016, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Rodger P McEver

  10. O-glycans direct selectin ligands to lipid rafts on leukocytes

    Article • Proceedings of the National Academy of Sciences, June 2015, Proceedings of the National Academy of Sciences

    Dr Rodger P McEver

  11. Selectins: initiators of leucocyte adhesion and signalling at the vascular wall

    Article • Cardiovascular Research, May 2015, European Society of Cardiology

    Dr Rodger P McEver

  12. Extracellular MRP8/14 is a regulator of β2 integrin-dependent neutrophil slow rolling and adhesion

    Article • Nature Communications, April 2015, Springer Science + Business Media

    Dr Rodger P McEver

  13. Cytoskeletal Regulation of CD44 Membrane Organization and Interactions with E-selectin

    Article • Journal of Biological Chemistry, October 2014, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Rodger P McEver

  14. Elevated CXCL1 expression in gp130-deficient endothelial cells impairs neutrophil migration in mice

    Article • Blood, September 2013, American Society of Hematology

    Dr Rodger P McEver

  15. Podoplanin maintains high endothelial venule integrity by interacting with platelet CLEC-2

    Article • Nature, September 2013, Springer Science + Business Media

    Dr Rodger P McEver

  16. P-Selectin Glycoprotein Ligand-1 Forms Dimeric Interactions with E-Selectin but Monomeric Interactions with L-Selectin on Cell Surfaces

    Article • PLoS ONE, February 2013, PLOS

    Dr Rodger P McEver

  17. Tyrosine Replacement of PSGL-1 Reduces Association Kinetics with P- and L-Selectin on the Cell Membrane

    Article • Biophysical Journal, August 2012, Elsevier

    Dr Rodger P McEver

  18. Leukocyte ligands for endothelial selectins: specialized glycoconjugates that mediate rolling and signaling under flow

    Article • Blood, October 2011, American Society of Hematology

    Dr Rodger P McEver

  19. Tyrosine Replacement Diminishes Association of PSGL-1 with P- and L-Selectins on the Cell Membrane

    Article • Biophysical Journal, February 2011, Elsevier

    Dr Rodger P McEver

  20. Rolling Cell Adhesion

    Article • Annual Review of Cell and Developmental Biology, November 2010, Annual Reviews

    Dr Rodger P McEver

  21. Triphasic Force Dependence of E-Selectin/Ligand Dissociation Governs Cell Rolling under Flow

    Article • Biophysical Journal, August 2010, Elsevier

    Dr Rodger P McEver

  22. Rolling back neutrophil adhesion

    Article • Nature Immunology, April 2010, Springer Science + Business Media

    Dr Rodger P McEver

  23. Bending rigidities of cell surface molecules P-selectin and PSGL-1

    Article • Journal of Biomechanics, February 2009, Elsevier

    Dr Rodger P McEver

  24. Chapter 7 Biophysical Regulation of Selectin–Ligand Interactions Under Flow

    Article • January 2009, Elsevier

    Dr Rodger P McEver

  25. A role for leukocyte-endothelial adhesion mechanisms in epilepsy

    Article • Nature Reports Stem Cells, November 2008, Springer Science + Business Media

    Dr Rodger P McEver

  26. Platelet glycoprotein Ibα forms catch bonds with human WT vWF but not with type 2B von Willebrand disease vWF

    Article • Journal of Clinical Investigation, August 2008, American Society for Clinical Investigation

    Dr Rodger P McEver

  27. Galectin-1 signaling in leukocytes requires expression of complex-type N-glycans

    Article • Glycobiology, June 2008, Oxford University Press (OUP)

    Dr Rodger P McEver

  28. Mechanisms for Flow-Enhanced Cell Adhesion

    Article • Annals of Biomedical Engineering, February 2008, Springer Science + Business Media

    Dr Rodger P McEver

  29. A nonsynonymous functional variant in integrin-αM (encoded by ITGAM) is associated with systemic lupus erythematosus

    Article • Nature Genetics, January 2008, Springer Science + Business Media

    Dr Rodger P McEver

  30. Monitoring Receptor-Ligand Interactions between Surfaces by Thermal Fluctuations

    Article • Biophysical Journal, January 2008, Elsevier

    Dr Rodger P McEver

  31. Clustering endothelial E-selectin in clathrin-coated pits and lipid rafts enhances leukocyte adhesion under flow

    Article • Blood, November 2007, American Society of Hematology

    Dr Rodger P McEver

  32. A catch to integrin activation

    Article • Nature Immunology, October 2007, Springer Science + Business Media

    Dr Rodger P McEver

  33. The Sliding–Rebinding Mechanism for Catch Bonds *

    Article • Japanese Journal of Applied Physics, August 2007, Japan Society of Applied Physics

    Dr Rodger P McEver

  34. IDENTIFYING THE MECHANISMS OF FLOW-ENHANCED CELL ADHESION VIA DIMENSIONAL ANALYSIS

    Article • June 2007, World Scientific Pub Co Pte Lt

    Dr Rodger P McEver

  35. A SLIDING-REBINDING MECHANISM FOR CATCH BONDS

    Article • June 2007, World Scientific Pub Co Pte Lt

    Dr Rodger P McEver

  36. Transport Governs Flow-Enhanced Cell Tethering through L-Selectin at Threshold Shear

    Article • Biophysical Journal, January 2007, Elsevier

    Dr Rodger P McEver

  37. P-Selectin/PSGL-1 and Other Interactions between Platelets, Leukocytes, and Endothelium

    Article • January 2007, Elsevier

    Dr Rodger P McEver

  38. Characterization of a sialic acid- and P-selectin glycoprotein ligand-1-independent adhesin activity in the granulocytotropic bacterium Anaplasma phagocytophilum

    Article • Cellular Microbiology, December 2006, Wiley

    Dr Rodger P McEver

  39. Probabilistic Modeling of Rosette Formation

    Article • Biophysical Journal, July 2006, Elsevier

    Dr Rodger P McEver

  40. Molecular and Cellular Contributions to Selectin-Dependent Leukocyte Adhesion Under Flow

    Article • May 2006, Wiley

    Dr Rodger P McEver

  41. Measuring Molecular Elasticity by Atomic Force Microscope Cantilever Fluctuations

    Article • Biophysical Journal, January 2006, Elsevier

    Dr Rodger P McEver

  42. Targeted Disruption of the Gene Encoding Core 1 β1‐3‐Galactosyltransferase (T‐Synthase) Causes Embryonic Lethality and Defective Angiogenesis in Mice

    Article • January 2006, Elsevier

    Dr Rodger P McEver

  43. A sulfated address for lymphocyte homing

    Article • Nature Immunology, November 2005, Springer Science + Business Media

    Dr Rodger P McEver

  44. Contributions of Ca2+ to Galectin-1-induced Exposure of Phosphatidylserine on Activated Neutrophils

    Article • Journal of Biological Chemistry, June 2005, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Rodger P McEver

  45. Force History Dependence of Receptor-Ligand Dissociation

    Article • Biophysical Journal, February 2005, Elsevier

    Dr Rodger P McEver

  46. Bone Marrow Is a Major Reservoir and Site of Recruitment for Central Memory CD8+ T Cells

    Article • Immunity, February 2005, Elsevier

    Dr Rodger P McEver

  47. Interactions of Selectins with PSGL-1 and Other Ligands

    Article • January 2004, Springer Science + Business Media

    Dr Rodger P McEver

  48. Interaction of P-selectin and PSGL-1 generates microparticles that correct hemostasis in a mouse model of hemophilia A

    Article • Nature Reports Stem Cells, July 2003, Springer Science + Business Media

    Dr Rodger P McEver

  49. Direct observation of catch bonds involving cell-adhesion molecules

    Article • Nature, May 2003, Springer Science + Business Media

    Dr Rodger P McEver

  50. Selectins: lectins that initiate cell adhesion under flow

    Article • Current Opinion in Cell Biology, October 2002, Elsevier

    Dr Rodger P McEver

  51. P-selectin glycoprotein ligand-1–deficient mice have impaired leukocyte tethering to E-selectin under flow

    Article • Journal of Clinical Investigation, April 2002, American Society for Clinical Investigation

    Dr Rodger P McEver

  52. P-selectin glycoprotein ligand-1–deficient mice have impaired leukocyte tethering to E-selectin under flow

    Article • Journal of Clinical Investigation, April 2002, American Society for Clinical Investigation

    Dr Rodger P McEver

  53. P-selectin glycoprotein ligand-1–deficient mice have impaired leukocyte tethering to E-selectin under flow

    Article • Journal of Clinical Investigation, April 2002, American Society for Clinical Investigation

    Dr Rodger P McEver

  54. AP-3 Adaptor Functions in Targeting P-Selectin to Secretory Granules in Endothelial Cells

    Article • Traffic, June 2001, Wiley

    Dr Rodger P McEver

  55. The Selectins in Leukocyte Recruitment

    Article • January 2001, Springer Science + Business Media

    Dr Rodger P McEver

  56. A Third Specificity-Determining Site in μ2 Adaptin for Sequences Upstream of YxxΦ Sorting Motifs

    Article • Traffic, January 2001, Wiley

    Dr Rodger P McEver

  57. Perspectives series: cell adhesion in vascular biology. Role of PSGL-1 binding to selectins in leukocyte recruitment.

    Article • Journal of Clinical Investigation, August 1997, American Society for Clinical Investigation

    Dr Rodger P McEver

  58. Structures of the O-Glycans on P-selectin Glycoprotein Ligand-1 from HL-60 Cells

    Article • Journal of Biological Chemistry, August 1996, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Rodger P McEver

  59. Residues Throughout the Cytoplasmic Domain Affect the Internalization Efficiency of P-selectin

    Article • Journal of Biological Chemistry, November 1995, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Rodger P McEver

  60. Neutrophils use both shared and distinct mechanisms to adhere to selectins under static and flow conditions.

    Article • Journal of Clinical Investigation, October 1995, American Society for Clinical Investigation

    Dr Rodger P McEver

  61. Regulation of the Human P-selectin Promoter by Bcl-3 and Specific Homodimeric Members of the NF- B/Rel Family

    Article • Journal of Biological Chemistry, September 1995, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Rodger P McEver

  62. Leukocyte trafficking mediated by selectin-carbohydrate interactions

    Article • Journal of Biological Chemistry, May 1995, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Rodger P McEver

  63. Regulation of Function and Expression of P-Selectin

    Article • January 1995, Springer Science + Business Media

    Dr Rodger P McEver

  64. Role of Selectins in Leukocyte Adhesion to Platelets and Endothelium

    Article • Annals of the New York Academy of Sciences, April 1994, Wiley

    Dr Rodger P McEver

  65. Selectins

    Article • Current Opinion in Immunology, February 1994, Elsevier

    Dr Rodger P McEver

  66. P-selectin mediates neutrophil rolling on histamine-stimulated endothelial cells

    Article • Biophysical Journal, October 1993, Elsevier

    Dr Rodger P McEver

  67. Inflammatory roles of P-selectin.

    Article • Journal of Clinical Investigation, August 1993, American Society for Clinical Investigation

    Dr Rodger P McEver

  68. Misguided leukocyte adhesion.

    Article • Journal of Clinical Investigation, June 1993, American Society for Clinical Investigation

    Dr Rodger P McEver

  69. Leukocyte Interactions Mediated by P-Selection

    Article • January 1993, Springer Science + Business Media

    Dr Rodger P McEver

  70. Identification of binding sites within the lectin domains of selectins that mediate leukocyte adherence

    Article • January 1993, Springer Science + Business Media

    Dr Rodger P McEver

  71. Leukocyte—endothelial cell interactions

    Article • Current Biology, November 1992, Elsevier

    Dr Rodger P McEver

  72. Leukocyte—endothelial cell interactions

    Article • Current Opinion in Cell Biology, October 1992, Elsevier

    Dr Rodger P McEver

  73. Adhesion: Its role in inflammatory disease

    Article • Immunology Today, January 1992, Elsevier

    Dr Rodger P McEver

  74. Selectins: A family of adhesion receptors

    Article • Cell, October 1991, Elsevier

    Dr Rodger P McEver

  75. GMP-140, a receptor that mediates interactions of leukocytes with activated platelets and endothelium

    Article • Trends in Cardiovascular Medicine, May 1991, Elsevier

    Dr Rodger P McEver

  76. GMP-140: A receptor for neutrophils and monocytes on activated platelets and endothelium

    Article • Journal of Cellular Biochemistry, February 1991, Wiley

    Dr Rodger P McEver

  77. Leukocyte Interactions Mediated by GMP-140

    Article • January 1991, Elsevier

    Dr Rodger P McEver

  78. Rapid neutrophil adhesion to activated endothelium mediated by GMP-140

    Article • Nature, February 1990, Springer Science + Business Media

    Dr Rodger P McEver

  79. Immunogold-surface replica study of ADP-induced ligand binding and fibrinogen receptor clustering in human platelets

    Article • American Journal of Anatomy, June 1989, Wiley

    Dr Rodger P McEver

  80. Cloning of GMP-140, a granule membrane protein of platelets and endothelium: Sequence similarity to proteins involved in cell adhesion and inflammation

    Article • Cell, March 1989, Elsevier

    Dr Rodger P McEver

  81. Isolation and Quantitation of the Platelet Membrane Glycoprotein Deficient in Thrombasthenia Using a Monoclonal Hybridoma Antibody

    Article • Journal of Clinical Investigation, December 1980, American Society for Clinical Investigation

    Dr Rodger P McEver

  82. P-Selectin

    Article • Cambridge University Press

    Dr Rodger P McEver

  83. Selectins

    Article • Wiley

    Dr Rodger P McEver

  84. P-selectin glycoprotein ligand-1 (PSGL-1)

    Article • Springer Science + Business Media

    Dr Rodger P McEver

  85. Selectin-Dependent Leukocyte Interactions with Vascular Surfaces

    Article • Springer Science + Business Media

    Dr Rodger P McEver