All Stories

  1. The endoplasmic reticulum membrane protein complex localizes to the mitochondrial - endoplasmic reticulum interface and its subunits modulate phospholipid biosynthesis in Trypanosoma brucei

    Article • PLoS Pathogens, May 2022, PLOS

    Professor Peter Bütikofer

  2. StaR-related lipid transfer-like domain-containing protein CLDP43 affects cardiolipin synthesis and mitochondrial function in Trypanosoma brucei

    Article • PLoS ONE, April 2022, PLOS

    Professor Peter Bütikofer

  3. TbIRK is a signature sequence free potassium channel from Trypanosoma brucei locating to acidocalcisomes

    Article • Scientific Reports, April 2017, Nature

    Professor Peter Bütikofer

  4. Translation Elongation and Termination: Are They Conserved Processes?

    Article • January 2016, Springer Science + Business Media

    Professor Peter Bütikofer

  5. Phosphatidylethanolamine and phosphatidylcholine biosynthesis by the Kennedy pathway occurs at different sites in Trypanosoma brucei

    Article • Scientific Reports, November 2015, Nature

    Professor Peter Bütikofer

  6. A heteromeric potassium channel involved in the modulation of the plasma membrane potential is essential for the survival of African trypanosomes

    Article • The FASEB Journal, August 2015, Federation of American Societies For Experimental Biology (FASEB)

    Professor Peter Bütikofer, Professor Erwin Sigel

  7. An Atypical Mitochondrial Carrier That Mediates Drug Action in Trypanosoma brucei

    Article • PLoS Pathogens, May 2015, PLOS

    Professor Peter Bütikofer

  8. Trypanosoma brucei Bloodstream Forms Depend upon Uptake ofmyo-Inositol for Golgi Complex Phosphatidylinositol Synthesis and Normal Cell Growth

    Article • Eukaryotic Cell, April 2015, ASM Journals

    Professor Peter Bütikofer, Professor Erwin Sigel

  9. A Glycosylation Mutant of Trypanosoma brucei Links Social Motility Defects In Vitro to Impaired Colonization of Tsetse Flies In Vivo

    Article • Eukaryotic Cell, April 2015, ASM Journals

    Professor Peter Bütikofer

  10. TrypanoCyc: a community-led biochemical pathways database for Trypanosoma brucei

    Article • Nucleic Acids Research, October 2014, Oxford University Press (OUP)

    Professor Peter Bütikofer, Professor Fred R. Opperdoes

  11. Trypanosoma brucei eflornithine transporter AAT6 is a low-affinity low-selective transporter for neutral amino acids

    Article • Biochemical Journal, October 2014, Portland Press Ltd.

    Professor Peter Bütikofer, Professor Erwin Sigel

  12. Autophagy in Trypanosoma brucei: Amino Acid Requirement and Regulation during Different Growth Phases

    Article • PLoS ONE, April 2014, PLOS

    Professor Peter Bütikofer

  13. Lipid synthesis in protozoan parasites: A comparison between kinetoplastids and apicomplexans

    Article • Progress in Lipid Research, October 2013, Elsevier

    Professor Peter Bütikofer

  14. Characterization of choline uptake in Trypanosoma brucei procyclic and bloodstream forms

    Article • Molecular and Biochemical Parasitology, July 2013, Elsevier

    Professor Peter Bütikofer, Professor Erwin Sigel

  15. Glycoprotein Biosynthesis in a Eukaryote Lacking the Membrane Protein Rft1

    Article • Journal of Biological Chemistry, May 2013, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Peter Bütikofer

  16. The ins and outs of phosphatidylethanolamine synthesis in Trypanosoma brucei

    Article • Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, March 2013, Elsevier

    Professor Peter Bütikofer

  17. Increased Placental Phospholipid Levels in Pre-Eclamptic Pregnancies

    Article • International Journal of Molecular Sciences, February 2013, MDPI AG

    Professor Peter Bütikofer

  18. Unique posttranslational modifications in eukaryotic translation factors and their roles in protozoan parasite viability and pathogenesis

    Article • Molecular and Biochemical Parasitology, January 2013, Elsevier

    Professor Peter Bütikofer

  19. Phosphatidylglycerophosphate synthase associates with a mitochondrial inner membrane complex and is essential for growth ofTrypanosoma brucei

    Article • Molecular Microbiology, December 2012, Wiley

    Professor Peter Bütikofer

  20. Eukaryotic Translation Elongation Factor 1A (eEF1A) Domain I from S. cerevisiae Is Required but Not Sufficient for Inter-Species Complementation

    Article • PLoS ONE, July 2012, PLOS

    Professor Peter Bütikofer

  21. An essential bacterial-type cardiolipin synthase mediates cardiolipin formation in a eukaryote

    Article • Proceedings of the National Academy of Sciences, March 2012, Proceedings of the National Academy of Sciences

    Professor Peter Bütikofer

  22. myo-Inositol Uptake Is Essential for Bulk Inositol Phospholipid but Not Glycosylphosphatidylinositol Synthesis in Trypanosoma brucei

    Article • Journal of Biological Chemistry, February 2012, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Peter Bütikofer

  23. Ethanolamine phosphoglycerol attachment to eEF1A is not essential for normal growth of Trypanosoma brucei

    Article • Scientific Reports, February 2012, Springer Science + Business Media

    Professor Peter Bütikofer

  24. The first identification of phosphatidylethanolamine in extremely halophilic Archaea

    Article • Chemistry and Physics of Lipids, August 2011, Elsevier

    Professor Peter Bütikofer

  25. Unique modifications of translation elongation factors

    Article • FEBS Journal, June 2011, Wiley

    Professor Peter Bütikofer

  26. Trypanosoma brucei: a model micro-organism to study eukaryotic phospholipid biosynthesis

    Article • FEBS Journal, February 2011, Wiley

    Professor Peter Bütikofer

  27. Lipid metabolism in Trypanosoma brucei

    Article • Molecular and Biochemical Parasitology, August 2010, Elsevier

    Professor Peter Bütikofer

  28. Characterisation of gp34, a GPI-anchored protein expressed by schizonts of Theileria parva and T. annulata

    Article • Molecular and Biochemical Parasitology, August 2010, Elsevier

    Professor Peter Bütikofer

  29. Lipid remodelling of glycosylphosphatidylinositol (GPI) glycoconjugates in procyclic-form trypanosomes: biosynthesis and processing of GPIs revisited

    Article • Biochemical Journal, June 2010, Portland Press Ltd.

    Professor Peter Bütikofer

  30. The protease resistant surface (PRS) glycoconjugate from Trypanosoma congolense has an inositol-acylated glycosylphosphatidylinositol anchor, containing a significant proportion of myristate at the sn-2 position

    Article • Molecular and Biochemical Parasitology, May 2010, Elsevier

    Professor Peter Bütikofer

  31. A Structural Domain Mediates Attachment of Ethanolamine Phosphoglycerol to Eukaryotic Elongation Factor 1A in Trypanosoma brucei

    Article • PLoS ONE, March 2010, PLOS

    Professor Peter Bütikofer

  32. Perturbation of phosphatidylethanolamine synthesis affects mitochondrial morphology and cell-cycle progression in procyclic-formTrypanosoma brucei

    Article • Molecular Microbiology, May 2009, Wiley

    Professor Peter Bütikofer

  33. Major Surface Glycoproteins of Insect Forms of Trypanosoma brucei Are Not Essential for Cyclical Transmission by Tsetse

    Article • PLoS ONE, February 2009, PLOS

    Professor Andrew Hemphill, Professor Peter Bütikofer

  34. Role of Protein Translocation Pathways across the Endoplasmic Reticulum in Trypanosoma brucei

    Article • Journal of Biological Chemistry, September 2008, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Peter Bütikofer

  35. Phosphatidylethanolamine in Trypanosoma brucei Is Organized in Two Separate Pools and Is Synthesized Exclusively by the Kennedy Pathway

    Article • Journal of Biological Chemistry, June 2008, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Peter Bütikofer

  36. Phosphatidylethanolamine Is the Precursor of the Ethanolamine Phosphoglycerol Moiety Bound to Eukaryotic Elongation Factor 1A

    Article • Journal of Biological Chemistry, April 2008, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Peter Bütikofer

  37. The Gup1 homologue of Trypanosoma brucei is a GPI glycosylphosphatidylinositol remodelase

    Article • Molecular Microbiology, November 2007, Wiley

    Professor Peter Bütikofer

  38. A distinct pool of phosphatidylethanolamine provides the ethanolamine for GPI and EPG modification of proteins

    Article • Chemistry and Physics of Lipids, September 2007, Elsevier

    Professor Peter Bütikofer

  39. Trypanosoma congolense Procyclins: Unmasking Cryptic Major Surface Glycoproteins in Procyclic Forms

    Article • Eukaryotic Cell, August 2006, ASM Journals

    Professor Peter Bütikofer

  40. GPI-specific phospholipase D (GPI-PLD) is expressed during mouse development and is localized to the extracellular matrix of the developing mouse skeleton

    Article • Bone, August 2005, Elsevier

    Professor Peter Bütikofer

  41. Phosphorylation of glycosyl-phosphatidylinositol by phosphatidylinositol 3-kinase changes its properties as a substrate for phospholipases

    Article • FEBS Letters, November 2004, Wiley

    Professor Peter Bütikofer

  42. Anti-Mouse GPI-PLD Antisera Highlight Structural Differences between Murine and Bovine GPI-PLDs

    Article • Biological Chemistry, December 2003, De Gruyter

    Professor Peter Bütikofer

  43. Coordinate Expression of GPEET Procyclin and Its Membrane-associated Kinase inTrypanosoma bruceiProcyclic Forms

    Article • Journal of Biological Chemistry, September 2003, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Peter Bütikofer

  44. Phosphorylation of GPEET procyclin is not necessary for survival of Trypanosoma brucei procyclic forms in culture and in the tsetse fly midgut

    Article • Molecular and Biochemical Parasitology, February 2003, Elsevier

    Professor Peter Bütikofer

  45. Characterisation and cellular localisation of a GPEET procyclin precursor in Trypanosoma brucei insect forms

    Article • Molecular and Biochemical Parasitology, January 2002, Elsevier

    Professor Peter Bütikofer

  46. Glycosylphosphatidylinositol-anchored surface molecules of Trypanosoma congolense insect forms are developmentally regulated in the tsetse fly

    Article • Molecular and Biochemical Parasitology, January 2002, Elsevier

    Professor Peter Bütikofer

  47. GPI-anchored proteins: now you see ’em, now you don’t

    Article • The FASEB Journal, February 2001, Federation of American Societies For Experimental Biology (FASEB)

    Professor Peter Bütikofer

  48. Conditional expression of glycosylphosphatidylinositol phospholipase C in Trypanosoma brucei

    Article • Molecular and Biochemical Parasitology, September 1999, Elsevier

    Professor Peter Bütikofer

  49. In Vitro Phosphorylation of Purified Glycosylphos-phatidylinositol-Specific Phospholipase D

    Article • Biological Chemistry, January 1999, De Gruyter

    Professor Peter Bütikofer

  50. ‘GPEET’ procyclin is the major surface protein of procyclic culture forms ofTrypanosoma brucei bruceistrain 427

    Article • Biochemical Journal, September 1997, Portland Press Ltd.

    Professor Peter Bütikofer

  51. Expression of intracellular and GPI-anchored forms of GPI-specific phospholipase D in COS-1 cells

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, July 1997, Elsevier

    Professor Peter Bütikofer

  52. Addition of G418 and other aminoglycoside antibiotics to mammalian cells results in the release of GPI-anchored proteins

    Article • FEBS Letters, June 1997, Wiley

    Professor Peter Bütikofer

  53. Uptake and intracellular stability of glycosylphosphatidylinositol-specific phospholipase D in neuroblastoma cells

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, March 1997, Elsevier

    Professor Peter Bütikofer

  54. The C-terminus of glycosylphosphatidylinositol-specific phospholipase D is essential for biological activity

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, February 1997, Elsevier

    Professor Peter Bütikofer

  55. Subcellular distribution of glycosylphosphatidylinositol-specific phospholipase D in rat liver

    Article • Biochemical Journal, November 1996, Portland Press Ltd.

    Professor Peter Bütikofer

  56. Phosphatidylinositol Hydrolysis byTrypanosoma bruceiGlycosylphosphatidylinositol Phospholipase C

    Article • Journal of Biological Chemistry, June 1996, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Peter Bütikofer

  57. Glycosyl inositolphospholipid-anchored structures in Herpetomonas davidi

    Article • Molecular and Biochemical Parasitology, October 1995, Elsevier

    Professor Peter Bütikofer

  58. Production of a Nested Set of Glycosylphosphatidylinositol Structures from a Glycosylphosphatidylinositol-Anchored Protein

    Article • Analytical Biochemistry, July 1995, Elsevier

    Professor Peter Bütikofer

  59. Generation by Limited Proteolysis of a Catalytically Active 39-kDa Protein from the 115-kDa form of Phosphatidylinositol-glycan-specific Phospholipase D from Bovine Serum

    Article • European Journal of Biochemistry, September 1994, Wiley

    Professor Peter Bütikofer

  60. Transbilayer mobility and distribution of red cell phospholipids during storage.

    Article • Journal of Clinical Investigation, July 1993, American Society for Clinical Investigation

    Professor Peter Bütikofer

  61. Generation of phosphatidic acid during calcium-loading of human erythrocytes. Evidence for a phosphatidylcholine-hydrolyzing phospholipase D

    Article • European Journal of Biochemistry, April 1993, Wiley

    Professor Peter Bütikofer

  62. Molecular species analysis of phospholipids from Trypanosoma brucei bloodstream and procyclic forms

    Article • Molecular and Biochemical Parasitology, March 1993, Elsevier

    Professor Peter Bütikofer, Prof Mark C Field

  63. Alkylacyl glycerophosphoinositol in human and bovine erythrocytes. Molecular species composition and comparison with glycosyl-inositolphospholipid anchors of erythrocyte acetylcholinesterases

    Article • European Journal of Biochemistry, September 1992, Wiley

    Professor Peter Bütikofer

  64. Application of liquid chromatography—thermospray mass spectrometry in the analysis of glycerophospholipid molecular species

    Article • Journal of Chromatography B Biomedical Sciences and Applications, January 1991, Elsevier

    Professor Peter Bütikofer

  65. Excess of red cell membrane proteins in hereditary high-phosphatidylcholine hemolytic anemia

    Article • American Journal of Hematology, July 1990, Wiley

    Professor Peter Bütikofer

  66. Preferential Release of Glycosyl-Phosphatidylinositol Anchored Proteins from Human Red Blood Cells during Vesiculation

    Article • January 1990, Springer Science + Business Media

    Professor Peter Bütikofer

  67. Haemolytic anaemia in analpha-lipoproteinaemia (Tangier disease): morphological, biochemical, and biophysical properties of the red blood cell

    Article • British Journal of Haematology, June 1989, Wiley

    Professor Peter Bütikofer

  68. Acetylcholinesterase in Mouse Neuroblastoma NB2A Cells: Analysis of Production, Secretion, and Molecular Forms

    Article • Journal of Neurochemistry, April 1989, Wiley

    Professor Peter Bütikofer

  69. Modulation of red cell vesiculation by protease inhibitors

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, November 1987, Elsevier

    Professor Peter Bütikofer

  70. Modulation of erythrocyte vesiculation by amphiphilic drugs

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, July 1987, Elsevier

    Professor Peter Bütikofer

  71. Effect of sickling on dimyristoylphosphatidylcholine-induced vesiculation in sickle red blood cells

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, February 1986, Elsevier

    Professor Peter Bütikofer

  72. The influence of cellular ATP levels on dimyristoylphosphatidylcholine-induced release of vesicles from human erythrocytes

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, November 1985, Elsevier

    Professor Peter Bütikofer

  73. ‘Crossed immunoblotting’: Identification of proteins after crossed immunoelectrophoresis and electrotransfer to nitrocellulose membranes

    Article • Journal of Immunological Methods, November 1985, Elsevier

    Professor Peter Bütikofer