All Stories

  1. Clinical Proteomics for Post-Hematopoeitic Stem Cell Transplantation Outcomes

    Article • PROTEOMICS - CLINICAL APPLICATIONS, October 2018, Wiley

    Professor Sophie Paczesny

  2. The search for drug-targetable diagnostic, prognostic and predictive biomarkers in chronic graft-versus-host disease

    Article • Expert Review of Clinical Immunology, April 2018, Taylor & Francis

    Professor Sophie Paczesny

  3. Acute Graft-Versus-Host Disease Prognosis: Are Biomarkers Ready for Preemptive Clinical Trials?

    Article • Clinical Chemistry, July 2017, AACC

    Professor Sophie Paczesny

  4. Proteomic Characterization Reveals That MMP-3 Correlates With Bronchiolitis Obliterans Syndrome Following Allogeneic Hematopoietic Cell and Lung Transplantation

    Article • American Journal of Transplantation, March 2016, Wiley

    Professor Sophie Paczesny

  5. National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: III. The 2014 Biomarker Working Group Report

    Article • Biology of Blood and Marrow Transplantation, May 2015, Elsevier

    Professor Sophie Paczesny

  6. Graft-versus-host disease in children after hematopoietic cell transplantation: potential clinical utility of biomarkers

    Article • International Journal of Hematologic Oncology, April 2015, Future Medicine

    Professor Sophie Paczesny

  7. A Biomarker Panel for Chronic Graft-Versus-Host Disease

    Article • Biology of Blood and Marrow Transplantation, February 2015, Elsevier

    Professor Sophie Paczesny

  8. Targeting ST2 Alleviates Graft-Versus-Host Disease Mortality and Maintains Graft-Versus-Leukemia

    Article • Biology of Blood and Marrow Transplantation, February 2015, Elsevier

    Professor Sophie Paczesny

  9. Plasma-Derived Proteomic Biomarkers Have Prognostic Utility in Patients Treated with Post-Transplantation Cyclophosphamide As Single-Agent Graft-Versus-Host Disease Prophylaxis for HLA-Matched Allogeneic Bone Marrow Transplantation

    Article • Biology of Blood and Marrow Transplantation, February 2015, Elsevier

    Professor Sophie Paczesny

  10. Various Forms of Tissue Damage and Danger Signals Following Hematopoietic Stem-Cell Transplantation

    Article • Frontiers in Immunology, January 2015, Frontiers

    Professor Sophie Paczesny

  11. Prognostic Biomarkers for Acute Graft-versus-Host Disease Risk after Cyclophosphamide–Fludarabine Nonmyeloablative Allotransplantation

    Article • Biology of Blood and Marrow Transplantation, November 2014, Elsevier

    Professor Sophie Paczesny

  12. Opportunities and challenges of proteomics in pediatric patients: Circulating biomarkers after hematopoietic stem cell transplantation as a successful example

    Article • PROTEOMICS - CLINICAL APPLICATIONS, October 2014, Wiley

    Professor Sophie Paczesny

  13. Engraftment Syndrome after Allogeneic Hematopoietic Cell Transplantation Predicts Poor Outcomes

    Article • Biology of Blood and Marrow Transplantation, September 2014, Elsevier

    Professor Sophie Paczesny

  14. Etanercept plus Topical Corticosteroids as Initial Therapy for Grade One Acute Graft-Versus-Host Disease after Allogeneic Hematopoietic Cell Transplantation

    Article • Biology of Blood and Marrow Transplantation, September 2014, Elsevier

    Professor Sophie Paczesny

  15. Aqueous two-phase systems enable multiplexing of homogeneous immunoassays

    Article • TECHNOLOGY, June 2014, World Scientific Pub Co Pte Lt

    Dr John P Frampton, Professor Sophie Paczesny, Shuichi Takayama

  16. Aqueous two-phase system patterning of detection antibody solutions for cross-reaction-free multiplex ELISA

    Article • Scientific Reports, May 2014, Springer Science + Business Media

    Dr John P Frampton, Professor Sophie Paczesny, Shuichi Takayama

  17. High Day 28 ST2 Biomarker Levels Predict Severe Day 100 Acute Graft-Versus-Host Disease and Day 180 Transplant-Related Mortality after Double-Unit Cord Blood Transplantation

    Article • Biology of Blood and Marrow Transplantation, February 2014, Elsevier

    Professor Sophie Paczesny

  18. Biomarkers for fatal immune response to stem cell treatment could reduce mortality

    Article • Biomarkers in Medicine, January 2014, Future Medicine

    Professor Sophie Paczesny

  19. Vorinostat plus tacrolimus and mycophenolate to prevent graft-versus-host disease after related-donor reduced-intensity conditioning allogeneic haemopoietic stem-cell transplantation: a phase 1/2 trial

    Article • The Lancet Oncology, January 2014, Elsevier

    Professor Sophie Paczesny

  20. Graft-versus-host disease biomarkers: omics and personalized medicine

    Article • International Journal of Hematology, August 2013, Springer Science + Business Media

    Professor Sophie Paczesny

  21. ST2 as a Marker for Risk of Therapy-Resistant Graft-versus-Host Disease and Death

    Article • New England Journal of Medicine, August 2013, New England Journal of Medicine (NEJM/MMS)

    Professor Sophie Paczesny

  22. Preprogrammed, Parallel On-Chip Immunoassay Using System-Level Capillarity Control

    Article • Analytical Chemistry, July 2013, American Chemical Society (ACS)

    Professor Sophie Paczesny, Shuichi Takayama

  23. Non-Relapse Mortality in Chronic Graft Versus Host Disease: Risk Factors At Onset and Reponse to Treatment

    Article • Biology of Blood and Marrow Transplantation, February 2013, Elsevier

    Professor Sophie Paczesny

  24. A Combination of Clinical Characteristics and Day 7 Biomarker Concentrations Predicts Graft-Versus-Host Disease Following Hematopoietic Cell Transplantation From Related Donors

    Article • Biology of Blood and Marrow Transplantation, February 2013, Elsevier

    Professor Sophie Paczesny

  25. Plasma ST2 Concentrations Predict Acute Gvhd Development and Non-Relapse Mortality

    Article • Biology of Blood and Marrow Transplantation, February 2013, Elsevier

    Professor Sophie Paczesny

  26. Preprogrammed capillarity to passively control system-level sequential and parallel microfluidic flows

    Article • Lab on a Chip, January 2013, Royal Society of Chemistry

    Professor Sophie Paczesny, Shuichi Takayama

  27. Proteomics in graft-versus-host disease and graft-versus-leukemia

    Article • January 2013, Elsevier

    Professor Sophie Paczesny

  28. Contributors

    Article • January 2013, Elsevier

    Professor Sophie Paczesny

  29. Discovery and validation of graft-versus-host disease biomarkers

    Article • Blood, November 2012, American Society of Hematology

    Professor Sophie Paczesny

  30. High Throughput Sequential ELISA for Validation of Biomarkers of Acute Graft-Versus-Host Disease

    Article • Journal of Visualized Experiments, October 2012, MyJove Corporation

    Professor Sophie Paczesny

  31. TNF-Inhibition with Etanercept for Graft-versus-Host Disease Prevention in High-Risk HCT: Lower TNFR1 Levels Correlate with Better Outcomes

    Article • Biology of Blood and Marrow Transplantation, October 2012, Elsevier

    Professor Sophie Paczesny

  32. Biomarkers for the detection of graft-versus-host disease in cancer patients after bone marrow transplantation

    Article • Current Biomarker Findings, August 2012, Taylor & Francis

    Professor Sophie Paczesny

  33. Role of Cytokines in the Pathophysiology of Acute Graft-Versus-Host Disease (GVHD)– Are Serum/Plasma Cytokines Potential Biomarkers for Diagnosis of Acute GVHD Following Allogeneic Hematopoietic Cell Transplantation (Allo-HCT)?

    Article • Current Stem Cell Research & Therapy, April 2012, Bentham Science Publishers

    Professor Sophie Paczesny

  34. Clinical Applications for Biomarkers of Acute and Chronic Graft-versus-Host Disease

    Article • Biology of Blood and Marrow Transplantation, January 2012, Elsevier

    Professor Sophie Paczesny

  35. Translational Research Efforts in Biomarkers and Biology of Early Transplant-Related Complications

    Article • Biology of Blood and Marrow Transplantation, January 2011, Elsevier

    Professor Sophie Paczesny

  36. Immunotherapy through T-cell receptor gene transfer induces severe graft-versus-host disease

    Article • Immunotherapy, November 2010, Future Medicine

    Professor Sophie Paczesny

  37. Frequency of CD4+CD25hiFOXP3+ Regulatory T Cells Has Diagnostic and Prognostic Value as a Biomarker for Acute Graft-versus-Host-Disease

    Article • Biology of Blood and Marrow Transplantation, July 2010, Elsevier

    Professor Sophie Paczesny

  38. Novel proteins associated with risk for coronary heart disease or stroke among postmenopausal women identified by in-depth plasma proteome profiling

    Article • Genome Medicine, January 2010, Springer Science + Business Media

    Professor Sophie Paczesny

  39. Mesenchymal Stem Cells for Treatment and Prevention of Graft-Versus- Host Disease After Allogeneic Hematopoietic Cell Transplantation

    Article • Current Stem Cell Research & Therapy, December 2009, Bentham Science Publishers

    Professor Sophie Paczesny

  40. New perspectives on the biology of acute GVHD

    Article • Bone Marrow Transplantation, November 2009, Springer Science + Business Media

    Professor Sophie Paczesny

  41. Acute graft-versus-host disease: new treatment strategies

    Article • Current Opinion in Hematology, November 2009, Wolters Kluwer Health

    Professor Sophie Paczesny

  42. Plasma Biomarkers in Graft-versus-Host Disease: A New Era?

    Article • Biology of Blood and Marrow Transplantation, January 2009, Elsevier

    Professor Sophie Paczesny

  43. Postmenopausal estrogen and progestin effects on the serum proteome

    Article • Genome Medicine, January 2009, Springer Science + Business Media

    Professor Sophie Paczesny

  44. Application of serum proteomics to the Women's Health Initiative conjugated equine estrogens trial reveals a multitude of effects relevant to clinical findings

    Article • Genome Medicine, January 2009, Springer Science + Business Media

    Professor Sophie Paczesny

  45. Plasma Elevations of Tumor Necrosis Factor-Receptor-1 at Day 7 Postallogeneic Transplant Correlate with Graft-versus-Host Disease Severity and Overall Survival in Pediatric Patients

    Article • Biology of Blood and Marrow Transplantation, July 2008, Elsevier

    Professor Sophie Paczesny

  46. Plasma Proteome Profiling of a Mouse Model of Breast Cancer Identifies a Set of Up-Regulated Proteins in Common with Human Breast Cancer Cells

    Article • Journal of Proteome Research, April 2008, American Chemical Society (ACS)

    Professor Sophie Paczesny

  47. Long-term outcomes in patients with metastatic melanoma vaccinated with melanoma peptide-pulsed CD34+ progenitor-derived dendritic cells

    Article • Cancer Immunology Immunotherapy, December 2005, Springer Science + Business Media

    Professor Sophie Paczesny

  48. Mesenchymal Stem Cells Inhibit Dendritic Cell Maturation and Their Allostimulatory Capacity

    Article • Journal of Pediatric Hematology/Oncology, September 2005, Wolters Kluwer Health

    Professor Sophie Paczesny

  49. Prompt Versus Preemptive Intervention With Cidofovir for Adenovirus Diseases After Allogeneic Stem Cell Transplantation: Impact on Survival in a Single Center Experience of 25 Patients

    Article • Journal of Pediatric Hematology/Oncology, September 2005, Wolters Kluwer Health

    Professor Sophie Paczesny

  50. Spontaneous Proliferation and Type 2 Cytokine Secretion by CD4+T Cells in Patients with Metastatic Melanoma Vaccinated with Antigen-Pulsed Dendritic Cells

    Article • Journal of Clinical Immunology, May 2005, Springer Science + Business Media

    Professor Sophie Paczesny

  51. Measuring Melanoma-Specific Cytotoxic T Lymphocytes Elicited by Dendritic Cell Vaccines with a Tumor Inhibition Assay In Vitro

    Article • Journal of Immunotherapy, March 2005, Wolters Kluwer Health

    Professor Sophie Paczesny

  52. Boosting Vaccinations with Peptide-Pulsed CD34+ Progenitor-Derived Dendritic Cells Can Expand Long-Lived Melanoma Peptide-Specific CD8+ T Cells in Patients with Metastatic Melanoma

    Article • Journal of Immunotherapy, March 2005, Wolters Kluwer Health

    Professor Sophie Paczesny

  53. Expansion of Melanoma-specific Cytolytic CD8 + T Cell Precursors in Patients with Metastatic Melanoma Vaccinated with CD34 + Progenitor-derived Dendritic Cells

    Article • The Journal of Experimental Medicine, June 2004, Rockefeller University Press

    Professor Sophie Paczesny

  54. Dendritic cells as vectors for immunotherapy of cancer

    Article • Seminars in Cancer Biology, December 2003, Elsevier

    Professor Sophie Paczesny

  55. Single Injection of CD34+ Progenitor-Derived Dendritic Cell Vaccine Can Lead to Induction of T-Cell Immunity in Patients With Stage IV Melanoma

    Article • Journal of Immunotherapy, September 2003, Wolters Kluwer Health

    Professor Sophie Paczesny

  56. Dendritic Cells

    Article • Annals of the New York Academy of Sciences, April 2003, Wiley

    Professor Sophie Paczesny

  57. Immunotherapy Via Dendritic Cells

    Article • Springer Science + Business Media

    Professor Sophie Paczesny