All Stories

  1. 2-Aminoethyldiphenyl Borinate: A Multitarget Compound with Potential as a Drug Precursor
  2. Effects of boron-containing compounds on immune responses: review and patenting trends
  3. Advances of Bioinformatics Applied to Development and Evaluation of Boron-Containing Compounds
  4. Current data regarding the structure-toxicity relationship of boron-containing compounds
  5. Insights on the role of boron containing moieties in the design of new potent and efficient agonists targeting the β2 adrenoceptor
  6. Insights into a defined secondary binding region on β-adrenoceptors and putative roles in ligand binding and drug design
  7. Triallelic digenic mutation in theprokineticin 2andGNRHreceptor genes in two brothers with normosmic congenital hypogonadotropic hypogonadism
  8. Anticonvulsant effects of bis-1,4-dihydropyridines and the probable role of L-type calcium channels suggested by docking simulations
  9. Boron-containing compounds: chemico-biological properties and expanding medicinal potential in prevention, diagnosis and therapy
  10. Molecular dynamics simulations to explore the active/inactive conformers of guinea pig β2adrenoceptor for the selective design of agonists or antagonists
  11. Boron-containing acids: Preliminary evaluation of acute toxicity and access to the brain determined by Raman scattering spectroscopy
  12. Recent Structural Advances of β1 and β2 Adrenoceptors Yield Keys for Ligand Recognition and Drug Design
  13. In Vitro and Molecular Modeling Analysis of Two Mutant Desert Hedgehog Proteins Associated with 46,XY Gonadal Dysgenesis
  14. o-Alkylselenenylated Benzoic Acid Accesses Several Sites in Serum Albumin According to Fluorescence Studies, Raman Spectroscopy and Theoretical Simulations
  15. Clinical Implications of Recent Insights into the Structural Biology of Beta2 Adrenoceptors
  16. Cell-based and in-silico studies on the high intrinsic activity of two boron-containing salbutamol derivatives at the human β2-adrenoceptor
  17. 2.238 COFFEE OR CHOCOLATE, WHAT DO YOU LIKE TO DRINK WITH YOUR L-DOPA?
  18. Give Boron a Chance: Boron Containing Compounds Reach Ionotropic and Metabotropic Transmembrane Receptors
  19. Theoretical study of 3-D molecular similarity and ligand binding modes of orthologous human and rat D2 dopamine receptors
  20. Homology model and docking studies on porcine β2 adrenoceptor: description of two binding sites
  21. Design, synthesis and in vitro evaluation of (R)-4-(2-(tert-butylamino)-1-hydroxyethyl)-2-(hydroxymethyl)phenyl hydrogen phenylboronate: A novel salbutamol derivative with high intrinsic efficacy on the β2 adrenoceptor
  22. Scope and Difficulty in Generating Theoretical Insights Regarding Ligand Recognition and Activation of the β 2 Adrenergic Receptor
  23. Pharmacokinetic parameters and a theoretical study about metabolism of BR-AEA (a salbutamol derivative) in rabbit
  24. Docking studies on a refined human β2 adrenoceptor model yield theoretical affinity values in function with experimental values for R-ligands, but not for S-antagonists
  25. Synthesis, pharmacological and in silico evaluation of 1-(4-di-hydroxy-3,5-dioxa-4-borabicyclo[4.4.0]deca-7,9,11-trien-9-yl)-2-(tert-butylamino)ethanol, a compound designed to act as a β2 adrenoceptor agonist
  26. Homology modeling and flex-ligand docking studies on the guinea pig β2 adrenoceptor: structural and experimental similarities/ differences with the human β2