All Stories

  1. Integration of sperm DNA damage assessment into OECD test guidelines for genotoxicity testing using the MutaMouse model
  2. Genomic chaos in peripheral blood lymphocytes of Hodgkin's lymphoma patients one year after ABVD chemotherapy/radiotherapy
  3. The adverse outcome pathway (AOP) for chemical binding to tubulin in oocytes leading to aneuploid offspring
  4. Development of the adverse outcome pathway “alkylation of DNA in male premeiotic germ cells leading to heritable mutations” using the OECD's users' handbook supplement
  5. Single-molecule PCR analysis of an unstable microsatellite for detecting mutations in sperm of mice exposed to chemical mutagens
  6. Approaches for identifying germ cell mutagens: Report of the 2013 IWGT workshop on germ cell assays☆
  7. Hydroxyurea induces chromosomal damage in G2 and enhances the clastogenic effect of mitomycin C in Fanconi anemia cells
  8. Sublinear response in lacZ mutant frequency of Muta ™ Mouse spermatogonial stem cells after low dose subchronic exposure to N‐ethyl‐N‐nitrosourea
  9. Meiotic interstrand DNA damage escapes paternal repair and causes chromosomal aberrations in the zygote by maternal misrepair
  10. Transgenic Rodent Assay for Quantifying Male Germ Cell Mutant Frequency
  11. Human sperm sex chromosome disomy and sperm DNA damage assessed by the neutral comet assay
  12. Transgenic Rodent Gene Mutation Assay in Somatic Tissues
  13. Nanosensor dosimetry of mouse blood proteins after exposure to ionizing radiation
  14. The development of adverse outcome pathways for mutagenic effects for the organization for economic co-operation and development
  15. No evidence for transgenerational genomic instability in the F1 or F2 descendants of Muta™Mouse males exposed to N-ethyl-N-nitrosourea
  16. Harnessing genomics to identify environmental determinants of heritable disease
  17. DNA Repair and Cell Cycle Biomarkers of Radiation Exposure and Inflammation Stress in Human Blood
  18. Micronutrients intake is associated with improved sperm DNA quality in older men
  19. Genetic Differences in Transcript Responses to Low-Dose Ionizing Radiation Identify Tissue Functions Associated with Breast Cancer Susceptibility
  20. Elemental composition of human semen is associated with motility and genomic sperm defects among older men
  21. Comparison of aneuploidies of chromosomes 21, X, and Y in the blood lymphocytes and sperm of workers exposed to benzene
  22. Occupational Exposure to Benzene and Chromosomal Structural Aberrations in the Sperm of Chinese Men
  23. Sidestream tobacco smoke is a male germ cell mutagen
  24. Low dose radiation response curves, networks and pathways in human lymphoblastoid cells exposed from 1 to 10cGy of acute gamma radiation
  25. Advances in understanding the genetic causes and mechanisms of female germ cell aneuploidy
  26. Benzene Exposure Near the U.S. Permissible Limit Is Associated with Sperm Aneuploidy
  27. Heterozygosity for a Bub1 mutation causes female-specific germ cell aneuploidy in mice
  28. Methyl-parathion decreases sperm function and fertilization capacity after targeting spermatocytes and maturing spermatozoa
  29. Differential sensitivity of male germ cells to mainstream and sidestream tobacco smoke in the mouse
  30. Molecular stress response in the CNS of mice after systemic exposure to interferon-α, ionizing radiation and ketamine
  31. Early Brain Response to Low-Dose Radiation Exposure Involves Molecular Networks and Pathways Associated with Cognitive Functions, Advanced Aging and Alzheimer's Disease
  32. Chromosomal Mosaicism in Mouse Two-Cell Embryos after Paternal Exposure to Acrylamide
  33. The association of folate, zinc and antioxidant intake with sperm aneuploidy in healthy non-smoking men
  34. DNA repair decline during mouse spermiogenesis results in the accumulation of heritable DNA damage
  35. Disruption of maternal DNA repair increases sperm-derived chromosomal aberrations
  36. The expression of Troponin T1 gene is induced by ketamine in adult mouse brain
  37. Reply: Sperm forward motion and aging
  38. Frequency of human sperm carrying structural aberrations of chromosome 1 increases with advancing age
  39. NTP-CERHR Expert Panel Report on the reproductive and developmental toxicity of hydroxyurea
  40. Assessing human germ-cell mutagenesis in the Postgenome Era: A celebration of the legacy of William Lawson (Bill) Russell
  41. The effects of male age on sperm DNA damage in healthy non-smokers
  42. Quantitative effects of male age on sperm motion
  43. Candidate protein biodosimeters of human exposure to ionizing radiation
  44. Etoposide induces chromosomal abnormalities in mouse spermatocytes and stem cell spermatogonia
  45. Human sperm-FISH for identifying potential paternal risk factors for chromosomally abnormal reproductive outcomes
  46. Mechanisms and consequences of paternally-transmitted chromosomal abnormalities
  47. Mechanisms and chemical induction of aneuploidy in rodent germ cells
  48. Cross-species sperm-FISH assays for chemical testing and assessing paternal risk for chromosomally abnormal pregnancies
  49. Impaired fertility in T-stock female mice after superovulation
  50. Differential basal expression of genes associated with stress response, damage control, and DNA repair among mouse tissues
  51. Detection of structural and numerical chromosomal abnormalities by ACM-FISH analysis in sperm of oligozoospermic infertility patients
  52. Paternally Transmitted Chromosomal Aberrations in Mouse Zygotes Determine Their Embryonic Fate
  53. A new FISH assay to simultaneously detect structural and numerical chromosomal abnormalities in mouse sperm
  54. CENP-B is not critical for meiotic chromosome segregation in male mice
  55. Etoposide induces heritable chromosomal aberrations and aneuploidy during male meiosis in the mouse
  56. Absence of Selection Against Aneuploid Mouse Sperm at Fertilization
  57. Induction of chromosomal aberrations in mouse zygotes by acrylamide treatment of male germ cells and their correlation with dominant lethality and heritable translocations
  58. Paternally inherited chromosomal structural aberrations detected in mouse first-cleavage zygote metaphases by multicolour fluorescencein situ hybridization painting
  59. Numerical and structural chromosome aberrations induced by etoposide (VP16) during oocyte maturation of mice: transmission to one-cell zygotes and damage to dictyate oocytes
  60. Mechanisms and targets involved in maternal and paternal age effects on numerical aneuploidy
  61. Dose-response study and threshold estimation of griseofulvin-induced aneuploidy during female mouse meiosis I and II
  62. Comparison of the aneugenic activity of diazepam in mouse oocytes and other mammalian cells
  63. Chemically-induced aneuploidy in mammalian oocytes
  64. Griseofulvin-induced aneuploidy and meiotic delay in mouse oocytes: effect of dose and harvest time
  65. The Relationship Between Chemically-Induced Meiotic Delay and Aneuploidy in Mouse Oocytes and Zygotes
  66. The effects of cisplatin on murine metaphase II oocytes
  67. Griseofulvin-induced aneuploidy and meiotic delay in female mouse germ cells. II. Cytogenetic analysis of one-cell zygotes
  68. Griseofulvin-induced aneuploidy and meiotic delay in female mouse germ cells. I. Cytogenetic analysis of metaphase II oocytes