All Stories

  1. Next-generation disulfide stapling: reduction and functional re-bridging all in one
  2. The Use of 3,6-Pyridazinediones in Organic Synthesis and Chemical Biology
  3. A plug-and-play approach to antibody-based therapeutics via a chemoselective dual click strategy
  4. A mild TCEP-based para-azidobenzyl cleavage strategy to transform reversible cysteine thiol labelling reagents into irreversible conjugates
  5. A novel synthetic chemistry approach to linkage-specific ubiquitin conjugation
  6. Pentafluorophenyl vinyl sulfonate enables efficient, metal-free, radical-based alkene hydroacylation with an aldehyde as a limiting reagent
  7. Site-selective multi-porphyrin attachment enables the formation of a next-generation antibody-based photodynamic therapeutic
  8. ChemInform Abstract: Acyl Hydrazides as Acyl Donors for the Synthesis of Diaryl and Aryl Alkyl Ketones.
  9. Targeting cancer cells with folic acid–iminoboronate fluorescent conjugates
  10. Acyl hydrazides as acyl donors for the synthesis of diaryl and aryl alkyl ketones
  11. A rapid, site-selective and efficient route to the dual modification of DARPins
  12. Optochemical Control of Engineered Trimeric P2X Receptors and Acid-Sensing Ion Channels
  13. A novel approach to the site-selective dual labelling of a protein via chemoselective cysteine modification
  14. E- and Z-Stereoselectivity in the preparation of enamides from glycidyl sulfonamides and carbamates
  15. Cover Picture: Bromomaleimide-Linked Bioconjugates Are Cleavable in Mammalian Cells (ChemBioChem 1/2012)
  16. Bromomaleimide-Linked Bioconjugates Are Cleavable in Mammalian Cells
  17. ChemInform Abstract: Functionalization of Aldehydes via Aerobic Hydroacylation of Azodicarboxylates “on” Water.
  18. ChemInform Abstract: Synthesis of γ-Ketophosphonates via Aerobic Hydroacylation of Vinyl Phosphonates.
  19. Synthesis of γ-ketophosphonates via aerobic hydroacylation of vinyl phosphonates
  20. Bromopyridazinedione-mediated protein and peptide bioconjugation
  21. Functionalisation of aldehydes via aerobic hydroacylation of azodicarboxylates ‘on’ water
  22. Hydroacylation of α,β-unsaturated esters via aerobic C–H activation
  23. ChemInform Abstract: Dioxygen Mediated Hydroacylation of Vinyl Sulfonates and Sulfones on Water.
  24. Dioxygen mediated hydroacylation of vinyl sulfonates and sulfones on water
  25. ChemInform Abstract: A Versatile Synthesis of 2,4-Substituted Oxazoles.
  26. A versatile synthesis of 2,4-substituted oxazoles