All Stories

  1. Design, Synthesis and Biological Evaluation of Novel Triazolothiadiazoles Derived from NSAIDs as Anticancer Agents

    Article • Anti-Cancer Agents in Medicinal Chemistry, April 2022, Bentham Science Publishers

    Dr Rengul Cetin-Atalay

  2. Synthesis and Cytotoxicity Studies on Novel Piperazinylacetamides

    Article • Letters in Drug Design & Discovery, November 2018, Bentham Science Publishers

    Dr Rengul Cetin-Atalay, Mine Yarim

  3. Differential alteration of IL-8 in liver cancer stem cell enrichment in response to PI3K/Akt/mTOR inhibitors and sorafenib

    Article • April 2018, Cold Spring Harbor Laboratory Press

    Dr Rengul Cetin-Atalay

  4. Development of a novel zebrafish xenograft model in ache mutants using liver cancer cell lines

    Article • Scientific Reports, January 2018, Springer Science + Business Media

    Dr Rengul Cetin-Atalay

  5. Synthesis of Novel Benzothiazole-Piperazine Derivatives and Their Biological Evaluation as Acetylcholinesterase Inhibitors and Cytotoxic Agents

    Article • Anti-Cancer Agents in Medicinal Chemistry, January 2018, Bentham Science Publishers

    Dr Rengul Cetin-Atalay, Mine Yarim, Hayrettin Ozan Gulcan

  6. Diagnostic Assessment of Deep Learning Algorithms for Detection of Lymph Node Metastases in Women With Breast Cancer

    Article • JAMA, December 2017, American Medical Association (AMA)

    Dr Rengul Cetin-Atalay

  7. Multiplication free neural network for cancer stem cell detection in H-and-E stained liver images

    Article • May 2017, SPIE

    Dr Rengul Cetin-Atalay

  8. Automated cancer stem cell recognition in H and E stained tissue using convolutional neural networks and color deconvolution

    Article • March 2017, SPIE

    Dr Rengul Cetin-Atalay

  9. Synthesis and biological evaluation of novel pyrazolic chalcone derivatives as novel hepatocellular carcinoma therapeutics

    Article • European Journal of Medicinal Chemistry, March 2017, Elsevier

    Dr Rengul Cetin-Atalay

  10. Quinoides and VEGFR2 TKIs influence the fate of hepatocellular carcinoma and its cancer stem cells

    Article • MedChemComm, January 2017, Royal Society of Chemistry

    Dr Rengul Cetin-Atalay

  11. Retinoid N-(1H-benzo[d]imidazol-2-yl)-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalene-2-carboxamide induces p21-dependent senescence in breast cancer cells

    Article • Steroids, April 2016, Elsevier

    Dr Rengul Cetin-Atalay

  12. Iterative h-minima-based marker-controlled watershed for cell nucleus segmentation

    Article • Cytometry, March 2016, Wiley

    Dr Rengul Cetin-Atalay

  13. Novel triazolothiadiazines act as potent anticancer agents in liver cancer cells through Akt and ASK-1 proteins

    Article • Bioorganic & Medicinal Chemistry, February 2016, Elsevier

    Dr Rengul Cetin-Atalay

  14. Phase and TV Based Convex Sets for Blind Deconvolution of Microscopic Images

    Article • IEEE Journal of Selected Topics in Signal Processing, February 2016, Institute of Electrical & Electronics Engineers (IEEE)

    Dr Rengul Cetin-Atalay

  15. Liver cancer cells are sensitive to Lanatoside C induced cell death independent of their PTEN status

    Article • Phytomedicine, January 2016, Elsevier

    Dr Rengul Cetin-Atalay

  16. Ynamide Click chemistry in development of triazole VEGFR2 TK modulators

    Article • European Journal of Medicinal Chemistry, October 2015, Elsevier

    Dr Rengul Cetin-Atalay

  17. Anti-cancer and anti-hepatitis C virus NS5B polymerase activity of etodolac 1,2,4-triazoles

    Article • Journal of Enzyme Inhibition and Medicinal Chemistry, August 2015, Taylor & Francis

    Dr Rengul Cetin-Atalay

  18. PATZ1 Is a DNA Damage-Responsive Transcription Factor That Inhibits p53 Function

    Article • Molecular and Cellular Biology, March 2015, ASM Journals

    Dr Rengul Cetin-Atalay

  19. Synthesis and Anticancer Activity Evaluation of Some Benzothiazole-Piperazine Derivatives

    Article • Anti-Cancer Agents in Medicinal Chemistry, March 2015, Bentham Science Publishers

    Dr Rengul Cetin-Atalay, Mine Yarim

  20. 3-Propionyl-thiazolidine-4-carboxylic acid ethyl esters: a family of antiproliferative thiazolidines

    Article • MedChemComm, January 2015, Royal Society of Chemistry

    Esra ONEN BAYRAM, Dr Rengul Cetin-Atalay, Mr KEREM BURAN

  21. Application of the Ugi reaction with multiple amino acid-derived components: synthesis and conformational evaluation of piperazine-based minimalist peptidomimetics

    Article • Organic & Biomolecular Chemistry, January 2015, Royal Society of Chemistry

    Alessandra silvani, Dr Rengul Cetin-Atalay

  22. The PI3K/AKT/mTOR interactive pathway

    Article • Molecular BioSystems, January 2015, Royal Society of Chemistry

    Dr Rengul Cetin-Atalay

  23. Synthesis of novel substituted purine derivatives and identification of the cell death mechanism

    Article • European Journal of Medicinal Chemistry, January 2015, Elsevier

    Dr Rengul Cetin-Atalay

  24. pH-responsive near-infrared emitting conjugated polymer nanoparticles for cellular imaging and controlled-drug delivery

    Article • Journal of Polymer Science Part A Polymer Chemistry, November 2014, Wiley

    Dr Rengul Cetin-Atalay

  25. Special issue on microscopic image processing

    Article • Signal Image and Video Processing, November 2014, Springer Science + Business Media

    Dr Rengul Cetin-Atalay

  26. Synthesis and preliminary mechanistic evaluation of 5-(p-tolyl)-1-(quinolin-2-yl)pyrazole-3-carboxylic acid amides with potent antiproliferative activity on human cancer cell lines

    Article • European Journal of Medicinal Chemistry, November 2014, Elsevier

    Dr Rengul Cetin-Atalay

  27. Near-IR Absorbing BODIPY Derivatives as Glutathione-Activated Photosensitizers for Selective Photodynamic Action

    Article • Chemistry - A European Journal, October 2014, Wiley

    Dr Rengul Cetin-Atalay

  28. Cytotoxic activities of some benzothiazole-piperazine derivatives

    Article • Journal of Enzyme Inhibition and Medicinal Chemistry, October 2014, Taylor & Francis

    Dr Rengul Cetin-Atalay, Mine Yarim

  29. Synthesis of 3-aroyl-4-aryl-1-isopropylamino-4-piperidinols and evaluation of the cytotoxicities of the compounds against human hepatoma and breast cancer cell lines

    Article • Journal of Enzyme Inhibition and Medicinal Chemistry, September 2014, Taylor & Francis

    Dr Rengul Cetin-Atalay

  30. A supervised learning model for live cell segmentation

    Article • April 2014, Institute of Electrical & Electronics Engineers (IEEE)

    Dr Rengul Cetin-Atalay

  31. Identification of Novel Reference Genes Based on MeSH Categories

    Article • PLoS ONE, March 2014, PLOS

    Dr Rengul Cetin-Atalay

  32. Dual functionality of conjugated polymer nanoparticles as an anticancer drug carrier and a fluorescent probe for cell imaging

    Article • RSC Advances, January 2014, Royal Society of Chemistry

    Dr Rengul Cetin-Atalay

  33. Synthesis of new N,N′-bis[1-aryl-3-(piperidine-1-yl)propylidene]hydrazine dihydrochlorides and evaluation of their cytotoxicity against human hepatoma and breast cancer cells

    Article • Journal of Enzyme Inhibition and Medicinal Chemistry, July 2013, Taylor & Francis

    Dr Rengul Cetin-Atalay

  34. Attributed Relational Graphs for Cell Nucleus Segmentation in Fluorescence Microscopy Images

    Article • IEEE Transactions on Medical Imaging, June 2013, Institute of Electrical & Electronics Engineers (IEEE)

    Dr Rengul Cetin-Atalay

  35. Genome-Wide Transcriptional Reorganization Associated with Senescence-to-Immortality Switch during Human Hepatocellular Carcinogenesis

    Article • PLoS ONE, May 2013, PLOS

    Dr Rengul Cetin-Atalay, Dr Gokhan YILDIZ, Prof Nejat Akar

  36. A multiplication-free framework for signal processing and applications in biomedical image analysis

    Article • May 2013, Institute of Electrical & Electronics Engineers (IEEE)

    Dr Rengul Cetin-Atalay

  37. Cytotoxic Activities of some Novel Benzhydrylpiperazine Derivatives

    Article • Drug Research, February 2013, Thieme Publishing Group

    Dr Rengul Cetin-Atalay

  38. Synthesis and cytotoxicity studies of novel benzhydrylpiperazine carboxamide and thioamide derivatives

    Article • Journal of Enzyme Inhibition and Medicinal Chemistry, February 2013, Taylor & Francis

    Dr Rengul Cetin-Atalay, Mine Yarim

  39. Image Classification of Human Carcinoma Cells Using Complex Wavelet-Based Covariance Descriptors

    Article • PLoS ONE, January 2013, PLOS

    Dr Rengul Cetin-Atalay

  40. Synthesis, anticancer activities and molecular modeling studies of novel indole retinoid derivatives

    Article • European Journal of Medicinal Chemistry, December 2012, Elsevier

    Dr Rengul Cetin-Atalay

  41. Smart Markers for Watershed-Based Cell Segmentation

    Article • PLoS ONE, November 2012, PLOS

    Dr Rengul Cetin-Atalay

  42. A novel thiazolidine compound induces caspase-9 dependent apoptosis in cancer cells

    Article • Bioorganic & Medicinal Chemistry, September 2012, Elsevier

    Esra ONEN BAYRAM, Dr Rengul Cetin-Atalay

  43. CD8 Lineage-specific Regulation of Interleukin-7 Receptor Expression by the Transcriptional Repressor Gfi1

    Article • Journal of Biological Chemistry, August 2012, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Rengul Cetin-Atalay

  44. Synthesis and Cytotoxic Activity of Novel 3-methyl-1-[(4-substitutedpiperazin-1-yl)methyl]-1H-indole Derivatives

    Article • Arzneimittelforschung, June 2012, Thieme Publishing Group

    Dr Rengul Cetin-Atalay

  45. Cancer Cell Cytotoxicities of 1-(4-Substitutedbenzoyl)-4-(4-chlorobenzhydryl)piperazine Derivatives

    Article • International Journal of Molecular Sciences, June 2012, MDPI AG

    Dr Rengul Cetin-Atalay, Mine Yarim

  46. Microscopic image classification via ℂWT-based covariance descriptors using Kullback-Leibler distance

    Article • May 2012, Institute of Electrical & Electronics Engineers (IEEE)

    Dr Rengul Cetin-Atalay

  47. Synthesis of Novel 6-(4-Substituted piperazine-1-yl)-9-(β- d -ribofuranosyl)purine Derivatives, Which Lead to Senescence-Induced Cell Death in Liver Cancer Cells

    Article • Journal of Medicinal Chemistry, April 2012, American Chemical Society (ACS)

    Dr Rengul Cetin-Atalay

  48. Carcinoma cell line discrimination in microscopic images using unbalanced wavelets

    Article • March 2012, Institute of Electrical & Electronics Engineers (IEEE)

    Dr Rengul Cetin-Atalay

  49. A signal transduction score flow algorithm for cyclic cellular pathway analysis, which combines transcriptome and ChIP-seq data

    Article • Molecular BioSystems, January 2012, Royal Society of Chemistry

    Dr Rengul Cetin-Atalay

  50. ChemInform Abstract: Design and Cytotoxic Evaluation of Some 1-Aryl-3-isopropylamino-1-propanone Hydrochlorides Towards Human Huh-7 Hepatoma Cells.

    Article • ChemInform, August 2011, Wiley

    Dr Rengul Cetin-Atalay

  51. Unsupervised segmentation of live cell images using Gaussian modeling

    Article • April 2011, Institute of Electrical & Electronics Engineers (IEEE)

    Dr Rengul Cetin-Atalay

  52. The Design and Cytotoxic Evaluation of Some 1-Aryl-3-isopropylamino-1-propanone Hydrochlorides towards Human Huh-7 Hepatoma Cells

    Article • Archiv der Pharmazie, February 2011, Wiley

    Dr Rengul Cetin-Atalay

  53. G-Network Modelling Based Abnormal Pathway Detection in Gene Regulatory Networks

    Article • January 2011, Springer Science + Business Media

    Dr Rengul Cetin-Atalay

  54. GOPred: GO Molecular Function Prediction by Combined Classifiers

    Article • PLoS ONE, August 2010, PLOS

    Dr Rengul Cetin-Atalay

  55. Data and Model Driven Hybrid Approach to Activity Scoring of Cyclic Pathways

    Article • August 2010, Springer Science + Business Media

    Dr Rengul Cetin-Atalay

  56. Inhibition of Akt signaling in hepatoma cells induces apoptotic cell death independent of Akt activation status

    Article • Investigational New Drugs, July 2010, Springer Science + Business Media

    Dr Rengul Cetin-Atalay

  57. Prediction of enzyme classes in a hierarchical approach by using SPMap

    Article • New Biotechnology, April 2010, Elsevier

    Dr Rengul Cetin-Atalay

  58. Bi-k-bi clustering: mining large scale gene expression data using two-level biclustering

    Article • International Journal of Data Mining and Bioinformatics, January 2010, Inderscience Publishers

    Dr Rengul Cetin-Atalay

  59. Nuclear Exclusion of p33ING1b Tumor Suppressor Protein: Explored in HCC Cells Using a New Highly Specific Antibody

    Article • February 2009, Mary Ann Liebert Inc

    Dr Rengul Cetin-Atalay

  60. MAb 15B9 Against p33ING1b Tumor Suppressor Protein

    Article • February 2009, Mary Ann Liebert Inc

    Dr Rengul Cetin-Atalay

  61. Subsequence-based feature map for protein function classification

    Article • Computational Biology and Chemistry, April 2008, Elsevier

    Dr Rengul Cetin-Atalay

  62. Short time series microarray data analysis and biological annotation

    Article • April 2008, Institute of Electrical & Electronics Engineers (IEEE)

    Dr Rengul Cetin-Atalay

  63. Liver Cancer, Molecular Biology of

    Article • September 2006, Wiley

    Dr Rengul Cetin-Atalay

  64. Reprogramming of replicative senescence in hepatocellular carcinoma-derived cells

    Article • Proceedings of the National Academy of Sciences, February 2006, Proceedings of the National Academy of Sciences

    Dr Rengul Cetin-Atalay

  65. Data Sources and Computational Approaches for Generating Models of Gene Regulatory Networks

    Article • January 2005, Wiley

    Dr Rengul Cetin-Atalay

  66. Implicit motif distribution based hybrid computational kernel for sequence classification

    Article • Bioinformatics, December 2004, Oxford University Press (OUP)

    Dr Rengul Cetin-Atalay

  67. An ontology for collaborative construction and analysis of cellular pathways

    Article • Bioinformatics, February 2004, Oxford University Press (OUP)

    Dr Rengul Cetin-Atalay

  68. A novel form of recessive limb girdle muscular dystrophy with mental retardation and abnormal expression of α-dystroglycan

    Article • Neuromuscular Disorders, December 2003, Elsevier

    Dr Rengul Cetin-Atalay

  69. Prediction of Protein Subcellular Localization Based on Primary Sequence Data

    Article • January 2003, Springer Science + Business Media

    Dr Rengul Cetin-Atalay

  70. PATIKA: an integrated visual environment for collaborative construction and analysis of cellular pathways

    Article • Bioinformatics, July 2002, Oxford University Press (OUP)

    Dr Rengul Cetin-Atalay

  71. Computer vision based mouse

    Article • May 2002, Institute of Electrical & Electronics Engineers (IEEE)

    Dr Rengul Cetin-Atalay

  72. Article • Virus Genes, January 2002, Springer Science + Business Media

    Dr Rengul Cetin-Atalay

  73. A monoclonal antibody against DNA binding helix of p53 protein

    Article • Oncogene, March 2001, Springer Science + Business Media

    Dr Rengul Cetin-Atalay

  74. p53 mutations as fingerprints of environmental carcinogens

    Article • Pure and Applied Chemistry, January 2000, De Gruyter

    Dr Rengul Cetin-Atalay

  75. Functional Role of the Noncatalytic Domains of Elongation Factor Tu in the Interactions with Ligands †

    Article • Biochemistry, January 1998, American Chemical Society (ACS)

    Dr Rengul Cetin-Atalay

  76. Prediction of protein subeellular localization based on primary sequence data

    Article • Institute of Electrical & Electronics Engineers (IEEE)

    Dr Rengul Cetin-Atalay

  77. Identification of relative protein bands in polyacrylamide gel electrophoresis (PAGE) using multiresolution snake algorithm

    Article • Institute of Electrical & Electronics Engineers (IEEE)

    Dr Rengul Cetin-Atalay

  78. A Novel Model-based Method for Feature Extraction from Protein Sequences for Classification

    Article • Institute of Electrical & Electronics Engineers (IEEE)

    Dr Rengul Cetin-Atalay