All Stories

  1. Binge drinking in young people: protocol for a systematic review of neuropsychological, neurophysiological and neuroimaging studies

    Article • BMJ Open, July 2018, BMJ

    Professor Caroline D Rae

  2. Brain bioenergetics during resting wakefulness are related to neurobehavioral deficits in severe obstructive sleep apnea: a 31P magnetic resonance spectroscopy study

    Article • SLEEP, June 2018, Oxford University Press (OUP)

    Professor Caroline D Rae

  3. On the Reliability of Individual Brain Activity Networks

    Article • IEEE Transactions on Medical Imaging, February 2018, Institute of Electrical & Electronics Engineers (IEEE)

    Professor Caroline D Rae

  4. The relationship between thalamic GABA content and resting cortical rhythm in neuropathic pain

    Article • Human Brain Mapping, January 2018, Wiley

    Prof Vaughan Gary Macefield, Dr Paul M Macey, Professor Caroline D Rae

  5. Covertly active and progressing neurochemical abnormalities in suppressed HIV infection

    Article • Neurology Neuroimmunology & Neuroinflammation, January 2018, Wolters Kluwer Health

    Professor Caroline D Rae

  6. Uncoupling N-acetylaspartate from brain pathology: implications for Canavan disease gene therapy

    Article • Acta Neuropathologica, November 2017, Springer Science + Business Media

    Professor Caroline D Rae

  7. An Objective Short Sleep Insomnia Disorder Subtype Is Associated With Reduced Brain Metabolite Concentrations In Vivo: A Preliminary Magnetic Resonance Spectroscopy Assessment

    Article • SLEEP, August 2017, Oxford University Press (OUP)

    Professor Caroline D Rae

  8. Erratum to: White matter measures are near normal in controlled HIV infection except in those with cognitive impairment and longer HIV duration

    Article • Journal of NeuroVirology, July 2017, Springer Science + Business Media

    Professor Caroline D Rae

  9. Glutathione in the human brain: Review of its roles and measurement by magnetic resonance spectroscopy

    Article • Analytical Biochemistry, July 2017, Elsevier

    Professor Caroline D Rae

  10. White matter measures are near normal in controlled HIV infection except in those with cognitive impairment and longer HIV duration

    Article • Journal of NeuroVirology, March 2017, Springer Science + Business Media

    Professor Caroline D Rae

  11. Acetate metabolism does not reflect astrocytic activity, contributes directly to GABA synthesis, and is increased by silent information regulator 1 activation

    Article • Journal of Neurochemistry, January 2017, Wiley

    Professor Caroline D Rae

  12. Toluene inhalation in adolescent rats reduces flexible behaviour in adulthood and alters glutamatergic and GABAergic signalling

    Article • Journal of Neurochemistry, November 2016, Wiley

    Professor Caroline D Rae

  13. β-Hydroxybutyrate in the Brain: One Molecule, Multiple Mechanisms

    Article • Neurochemical Research, November 2016, Springer Science + Business Media

    Professor Caroline D Rae

  14. Metabolomics of Neurotransmitters and Related Metabolites in Post-Mortem Tissue from the Dorsal and Ventral Striatum of Alcoholic Human Brain

    Article • Neurochemical Research, January 2016, Springer Science + Business Media

    Professor Caroline D Rae

  15. Astrocytes, Metabolism, Signaling and Brain Drains: Introduction to the Special Issue in Honor of Gerald Dienel

    Article • Neurochemical Research, November 2015, Springer Science + Business Media

    Professor Caroline D Rae

  16. Creatine as a booster for human brain function. How might it work?

    Article • Neurochemistry International, October 2015, Elsevier

    Professor Caroline D Rae

  17. A new role for α-ketoglutarate dehydrogenase complex: regulating metabolism through post-translational modification of other enzymes

    Article • Journal of Neurochemistry, June 2015, Wiley

    Professor Caroline D Rae

  18. Brain Activity: Connectivity, Sparsity, and Mutual Information

    Article • IEEE Transactions on Medical Imaging, April 2015, Institute of Electrical & Electronics Engineers (IEEE)

    Professor Caroline D Rae

  19. Upper limb function is normal in patients with restless legs syndrome (Willis-Ekbom Disease)

    Article • Clinical Neurophysiology, April 2015, Elsevier

    Professor Caroline D Rae

  20. Brain activity: Conditional dissimilarity and persistent homology

    Article • April 2015, Institute of Electrical & Electronics Engineers (IEEE)

    Professor Caroline D Rae

  21. Silent information regulator 1 modulator resveratrol increases brain lactate production and inhibits mitochondrial metabolism, whereas SRT1720 increases oxidative metabolism

    Article • Journal of Neuroscience Research, February 2015, Wiley

    Professor Caroline D Rae

  22. Metabolomic Approaches to Defining the Role(s) of GABAρ Receptors in the Brain

    Article • Journal of Neuroimmune Pharmacology, January 2015, Springer Science + Business Media

    Professor Caroline D Rae

  23. Alterations of GABA and glutamate–glutamine levels in premenstrual dysphoric disorder: A 3T proton magnetic resonance spectroscopy study

    Article • Psychiatry Research Neuroimaging, January 2015, Elsevier

    Professor Caroline D Rae

  24. The Energetic Cost of a Night on the Town

    Article • SLEEP, December 2014, Associated Professional Sleep Societies (APSS)

    Professor Caroline D Rae

  25. Do maternal opioids reduce neonatal regional brain volumes? A pilot study

    Article • Journal of Perinatology, June 2014, Springer Science + Business Media

    Professor Caroline D Rae

  26. Hand function is impaired in healthy older adults at risk of Parkinson’s disease

    Article • Journal of Neural Transmission, May 2014, Springer Science + Business Media

    Professor Caroline D Rae

  27. Thalamic activity and biochemical changes in individuals with neuropathic pain after spinal cord injury

    Article • Pain, May 2014, Wolters Kluwer Health

    Professor Caroline D Rae

  28. A Chip Off the Old Block: The Brain Slice as a Model for Metabolic Studies of Brain Compartmentation and Neuropharmacology

    Article • January 2014, Springer Science + Business Media

    Professor Caroline D Rae

  29. Ethanol, not detectably metabolized in brain, significantly reduces brain metabolism, probably via action at specific GABA(A) receptors and has measureable metabolic effects at very low concentrations

    Article • Journal of Neurochemistry, December 2013, Wiley

    Professor Caroline D Rae

  30. A Guide to the Metabolic Pathways and Function of Metabolites Observed in Human Brain 1H Magnetic Resonance Spectra

    Article • Neurochemical Research, November 2013, Springer Science + Business Media

    Professor Caroline D Rae

  31. Resistance training improves cardiac output, exercise capacity and tolerance to positive airway pressure in Fontan physiology

    Article • International Journal of Cardiology, September 2013, Elsevier

    Professor Caroline D Rae

  32. Skeletal muscle abnormalities and exercise capacity in adults with a Fontan circulation

    Article • Heart, July 2013, BMJ

    Professor Caroline D Rae

  33. Training the brain and its connections to muscles

    Article • Journal of Applied Physiology, May 2013, American Physiological Society

    Professor Caroline D Rae

  34. Chronic Pain: Lost Inhibition?

    Article • Journal of Neuroscience, April 2013, Society for Neuroscience

    Professor Caroline D Rae

  35. HIV, Vascular and Aging Injuries in the Brain of Clinically Stable HIV-Infected Adults: A 1H MRS Study

    Article • PLoS ONE, April 2013, PLOS

    Professor Caroline D Rae

  36. Direct mapping of T2* signal changes induced by Transcranial Direct Current Stimulation

    Article • April 2013, Institute of Electrical & Electronics Engineers (IEEE)

    Professor Caroline D Rae

  37. Anodal transcranial direct current stimulation increases brain intracellular pH and modulates bioenergetics

    Article • The International Journal of Neuropsychopharmacology, March 2013, Oxford University Press (OUP)

    Professor Caroline D Rae

  38. Glutamate Metabolism is Impaired in Transgenic Mice with Tau Hyperphosphorylation

    Article • Journal of Cerebral Blood Flow & Metabolism, January 2013, SAGE Publications

    Professor Caroline D Rae

  39. Magnetic Resonance-Based Metabolomics for Understanding Neurological Disorders: Current Status and Statistical Considerations

    Article • Current Metabolomics, November 2012, Bentham Science Publishers

    Professor Caroline D Rae

  40. Combining MR elastography and diffusion tensor imaging for the assessment of anisotropic mechanical properties: A phantom study

    Article • Journal of Magnetic Resonance Imaging, September 2012, Wiley

    Professor Caroline D Rae

  41. Metabolism, Compartmentation, Transport and Production of Acetate in the Cortical Brain Tissue Slice

    Article • Neurochemical Research, August 2012, Springer Science + Business Media

    Professor Caroline D Rae

  42. Identifying fMRI Model Violations With Lagrange Multiplier Tests

    Article • IEEE Transactions on Medical Imaging, July 2012, Institute of Electrical & Electronics Engineers (IEEE)

    Professor Caroline D Rae

  43. Statistical Total Correlation Spectroscopy Scaling for Enhancement of Metabolic Information Recovery in Biological NMR Spectra

    Article • Analytical Chemistry, January 2012, American Chemical Society (ACS)

    Professor Caroline D Rae

  44. Activity-dependent γ-aminobutyric acid release controls brain cortical tissue slice metabolism

    Article • Journal of Neuroscience Research, May 2011, Wiley

    Professor Caroline D Rae

  45. Time-to-Onset latency in fMRI: Fast detection of delayed activation

    Article • May 2011, Institute of Electrical & Electronics Engineers (IEEE)

    Professor Caroline D Rae

  46. Statistical Integration of 1 H NMR and MRS Data from Different Biofluids and Tissues Enhances Recovery of Biological Information from Individuals with HIV-1 infection

    Article • Journal of Proteome Research, April 2011, American Chemical Society (ACS)

    Professor Caroline D Rae

  47. Pyruvate Carboxylation in Different Model Systems Studied by 13C MRS

    Article • Neurochemical Research, September 2010, Springer Science + Business Media

    Professor Caroline D Rae

  48. γ-Hydroxybutyrate and the GABAergic footprint: a metabolomic approach to unpicking the actions of GHB

    Article • Journal of Neurochemistry, July 2010, Wiley

    Professor Caroline D Rae

  49. Corpus Callosum Morphology and Its Relationship to Cognitive Function in Neurofibromatosis Type 1

    Article • Journal of Child Neurology, February 2010, SAGE Publications

    Professor Caroline D Rae

  50. Bootstrap quantification of cardiac pulsation artifact in DTI

    Article • NeuroImage, January 2010, Elsevier

    Professor Caroline D Rae

  51. RE: Magnetic resonance spectroscopy of the brain: review of metabolites and clinical applications

    Article • Clinical Radiology, October 2009, Elsevier

    Professor Caroline D Rae

  52. A metabonomic study of inhibition of GABA uptake in the cerebral cortex

    Article • Metabolomics, August 2009, Springer Science + Business Media

    Professor Caroline D Rae

  53. Rottlerin Inhibits (Na+, K+)-ATPase Activity in Brain Tissue and Alters d-Aspartate Dependent Redistribution of Glutamate Transporter GLAST in Cultured Astrocytes

    Article • Neurochemical Research, June 2009, Springer Science + Business Media

    Professor Caroline D Rae

  54. Dynamic Changes in Brain Bioenergetics during Obstructive Sleep Apnea

    Article • Journal of Cerebral Blood Flow & Metabolism, May 2009, SAGE Publications

    Professor Caroline D Rae

  55. Now I know my ABC. A systems neurochemistry and functional metabolomic approach to understanding the GABAergic system

    Article • Journal of Neurochemistry, May 2009, Wiley

    Professor Caroline D Rae

  56. Metabolic Effects of Blocking Lactate Transport in Brain Cortical Tissue Slices Using an Inhibitor Specific to MCT1 and MCT2

    Article • Neurochemical Research, April 2009, Springer Science + Business Media

    Professor Caroline D Rae

  57. Understanding your inhibitions: effects of GABA and GABAAreceptor modulation on brain cortical metabolism

    Article • Journal of Neurochemistry, January 2009, Wiley

    Professor Caroline D Rae

  58. Metabolite profiling of the intraerythrocytic malaria parasite Plasmodium falciparum by 1 H NMR spectroscopy

    Article • NMR in Biomedicine, November 2008, Wiley

    Professor Caroline D Rae

  59. Mind Meld: Collaborative Approaches to Understanding How We All Think

    Article • Brain Imaging and Behavior, October 2008, Springer Science + Business Media

    Professor Caroline D Rae

  60. Alanine metabolism, transport, and cycling in the brain

    Article • Journal of Neurochemistry, May 2007, Wiley

    Professor Caroline D Rae

  61. The effects of large neutral amino acid supplements in PKU: An MRS and neuropsychological study

    Article • Molecular Genetics and Metabolism, May 2007, Elsevier

    Professor Caroline D Rae

  62. Piece of mind; a full systems approach is required

    Article • Behavioral and Brain Sciences, April 2007, Cambridge University Press

    Professor Caroline D Rae

  63. Understanding Your Inhibitions: Modulation of Brain Cortical Metabolism by GABABReceptors

    Article • Journal of Cerebral Blood Flow & Metabolism, February 2007, SAGE Publications

    Professor Caroline D Rae

  64. Modulation of brain metabolism by very low concentrations of the commonly used drug delivery vehicle dimethyl sulfoxide (DMSO)

    Article • Journal of Neuroscience Research, January 2007, Wiley

    Professor Caroline D Rae

  65. Inhibitors of glutamate transport modulate distinct patterns in brain metabolism

    Article • Journal of Neuroscience Research, January 2007, Wiley

    Professor Caroline D Rae

  66. Brain metabolic markers reflect susceptibility status in cytokine gene knockout mice with murine cerebral malaria

    Article • International Journal for Parasitology, November 2006, Elsevier

    Professor Caroline D Rae

  67. Immunopathogenesis of cerebral malaria

    Article • International Journal for Parasitology, May 2006, Elsevier

    Professor Caroline D Rae

  68. A Metabolomic Approach to Ionotropic Glutamate Receptor Subtype Function: A Nuclear Magnetic Resonancein vitroInvestigation

    Article • Journal of Cerebral Blood Flow & Metabolism, December 2005, SAGE Publications

    Professor Caroline D Rae

  69. Metabolites from cerebrospinal fluid in aneurysmal subarachnoid haemorrhage correlate with vasospasm and clinical outcome: a pattern-recognition1H NMR study

    Article • NMR in Biomedicine, January 2005, Wiley

    Professor Caroline D Rae

  70. Group I and II metabotropic glutamate receptors alter brain cortical metabolic and glutamate/glutamine cycle activity: a 13C NMR spectroscopy and metabolomic study

    Article • Journal of Neurochemistry, January 2005, Wiley

    Professor Caroline D Rae

  71. An Investigation of Neuronal Integrity in Severe Paediatric Traumatic Brain Injury

    Article • Child Neuropsychology, December 2004, Taylor & Francis

    Professor Caroline D Rae

  72. Hippocampal area metabolites relate to severity and cognitive function in obstructive sleep apnea

    Article • Sleep Medicine, November 2004, Elsevier

    Professor Caroline D Rae

  73. EFFECTS OF GLUTAMATE TRANSPORT SUBSTRATES AND GLUTAMATE RECEPTOR LIGANDS ON THE ACTIVITY OF Na+/K+-ATPase IN BRAIN TISSUE IN VITRO

    Article • Clinical and Experimental Pharmacology and Physiology, November 2004, Wiley

    Professor Caroline D Rae

  74. Brain gene expression, metabolism, and bioenergetics: interrelationships in murine models of cerebral and noncerebral malaria

    Article • The FASEB Journal, March 2004, Wiley

    Professor Caroline D Rae

  75. Enlarged Temporal Lobes in Turner Syndrome: An X-chromosome Effect?

    Article • Cerebral Cortex, February 2004, Oxford University Press (OUP)

    Professor Caroline D Rae

  76. For want of a nail. ramifications of a single gene deletion, dystrophin, in the brain of the mouse

    Article • Frontiers in Bioscience, January 2004, Frontiers in Bioscience

    Professor Caroline D Rae

  77. Oral creatine monohydrate supplementation improves brain performance: a double-blind, placebo-controlled, cross-over trial

    Article • Proceedings of the Royal Society B Biological Sciences, October 2003, Royal Society Publishing

    Professor Caroline D Rae

  78. Memory training alters hippocampal neurochemistry in healthy elderly

    Article • Neuroreport, July 2003, Wolters Kluwer Health

    Professor Perminder S Sachdev, Professor Caroline D Rae

  79. Inhibition of glutamine transport depletes glutamate and GABA neurotransmitter pools: further evidence for metabolic compartmentation

    Article • Journal of Neurochemistry, April 2003, Wiley

    Professor Caroline D Rae, Dr Nathan J Hare

  80. Creatine Supplementation Affects Glucose Homeostasis but Not Insulin Secretion in Humans

    Article • Annals of Nutrition and Metabolism, January 2003, Karger Publishers

    Professor Caroline D Rae

  81. Compartmentation of metabolism probed by [2-13C]alanine: improved 13C NMR sensitivity using a CryoProbe detects evidence of a glial metabolon

    Article • Neurochemistry International, January 2003, Elsevier

    Professor Caroline D Rae

  82. Brain Bioenergetics and Cognitive Ability

    Article • Developmental Neuroscience, January 2003, Karger Publishers

    Professor Caroline D Rae

  83. Abnormalities in brain biochemistry associated with lack of dystrophin: studies of the mdx mouse

    Article • Neuromuscular Disorders, February 2002, Elsevier

    Professor Caroline D Rae

  84. Brain function in Duchenne muscular dystrophy

    Article • Brain, January 2002, Oxford University Press (OUP)

    Professor Caroline D Rae

  85. Article • Neurochemical Research, January 2002, Springer Science + Business Media

    Professor Caroline D Rae

  86. Cerebellar morphology in developmental dyslexia

    Article • Neuropsychologia, January 2002, Elsevier

    Professor Caroline D Rae

  87. Hypo-osmotic swelling-activated release of organic osmolytes in brain slices: implications for brain oedema in vivo

    Article • Journal of Neurochemistry, December 2001, Wiley

    Professor Caroline D Rae

  88. Metabolic Profiling of Genetic Disorders: A Multitissue 1H Nuclear Magnetic Resonance Spectroscopic and Pattern Recognition Study into Dystrophic Tissue

    Article • Analytical Biochemistry, June 2001, Elsevier

    Professor Caroline D Rae

  89. 1 H NMR of compounds with low water solubility in the presence of erythrocytes: effects of emulsion phase separation

    Article • European Biophysics Journal, April 2001, Springer Science + Business Media

    Professor Caroline D Rae

  90. Strategies for studies of neurotoxic mechanisms involving deficient transport of L-glutamate: antisense knockout in rat brain in vivo and changes in the neurotransmitter metabolism following inhibition of glutamate transport in guinea pig brain slices

    Article • Brain Research Bulletin, November 2000, Elsevier

    Professor Caroline D Rae

  91. Dichloroacetate (DCA) reduces brain lactate but increases brain glutamine in experimental cerebral malaria: a1H-NMR study

    Article • Redox Report, April 2000, Taylor & Francis

    Professor Caroline D Rae

  92. Increased permeability of the malaria-infected erythrocyte to organic cations

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, January 2000, Elsevier

    Professor Caroline D Rae

  93. Lactate-induced inhibition of glucose catabolism in guinea pig cortical brain slices

    Article • Neurochemistry International, November 1999, Elsevier

    Professor Caroline D Rae

  94. Delayed labelling of brain glutamate after an intra-arterial [13C]glucose bolus: evidence for aerobic metabolism of guinea pig brain glycogen store

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, July 1999, Elsevier

    Professor Caroline D Rae

  95. Reduced cytosolic acidification during exercise suggests defective glycolytic activity in skeletal muscle of patients with Becker muscular dystrophy: An in vivo 31P magnetic resonance spectroscopy study

    Article • Brain, January 1999, Oxford University Press (OUP)

    Professor Caroline D Rae

  96. Brain biochemistry in Duchenne muscular dystrophy: A 1H magnetic resonance and neuropsychological study

    Article • Journal of the Neurological Sciences, October 1998, Elsevier

    Professor Caroline D Rae

  97. Metabolic abnormalities in developmental dyslexia detected by 1H magnetic resonance spectroscopy

    Article • The Lancet, June 1998, Elsevier

    Professor Caroline D Rae

  98. Brain abnormalities in Duchenne muscular dystrophy: phosphorus-31 magnetic resonance spectroscopy and neuropsychological study

    Article • The Lancet, May 1995, Elsevier

    Professor Caroline D Rae

  99. Stereospecificity of Substrate Usage by Glyoxalase 1: Nuclear Magnetic Resonance Studies of Kinetics and Hemithioacetal Substrate Conformation

    Article • Biochemistry, March 1994, American Chemical Society (ACS)

    Professor Caroline D Rae

  100. Stability and nonreactivity of ergothioneine in human erythrocytes studied by1H NMR

    Article • Magnetic Resonance in Medicine, June 1993, Wiley

    Professor Caroline D Rae

  101. Comparison of the 1H and 31P NMR Spectra of Erythrocytes and Plasma from some Australian Native Animals: Bandicoot, Echidna, Koala, Little Penguin, Tammar Wallaby, Tasmanian Devil, Tree Kangaroo and Wombat

    Article • January 1993, Springer Science + Business Media

    Professor Caroline D Rae

  102. Glyoxalase 2 deficiency in the erythrocytes of a horse: 1H NMR studies of enzyme kinetics and transport of S-lactoylglutathione

    Article • Archives of Biochemistry and Biophysics, December 1991, Elsevier

    Professor Caroline D Rae

  103. Changes in Hepatic Glutathione Metabolism in Diabetes

    Article • Diabetes, March 1991, American Diabetes Association

    Professor Caroline D Rae

  104. 1H NMR spectroscopic survey of plasma and erythrocytes from selected marsupials and domestic animals of Australia

    Article • Comparative Biochemistry and Physiology Part B Comparative Biochemistry, January 1991, Elsevier

    Professor Caroline D Rae

  105. Kinetic analysis of the human erythrocyte glyoxalase system using 1H NMR and a computer model

    Article • European Journal of Biochemistry, October 1990, Wiley

    Professor Caroline D Rae