All Stories

  1. Assessing the population relevance of endocrine‐disrupting effects for nontarget vertebrates exposed to plant protection products

    Article • Integrated Environmental Assessment and Management, January 2019, Wiley

    Dr James R Wheeler

  2. Advancing the assessment of population stability as a protection goal in ecotoxicology

    Article • Integrated Environmental Assessment and Management, December 2017, Wiley

    Dr James R Wheeler

  3. A review of the evidence for endocrine disrupting effects of current-use chemicals on wildlife populations

    Article • Critical Reviews in Toxicology, November 2017, Taylor & Francis

    Dr James R Wheeler

  4. Reducing repetition of regulatory vertebrate ecotoxicology studies

    Article • Integrated Environmental Assessment and Management, August 2017, Wiley

    Dr James R Wheeler

  5. Recommended approaches to the scientific evaluation of ecotoxicological hazards and risks of endocrine-active substances

    Article • Integrated Environmental Assessment and Management, January 2017, Wiley

    Dr James R Wheeler

  6. Uncertainties in biological responses that influence hazard and risk approaches to the regulation of endocrine active substances

    Article • Integrated Environmental Assessment and Management, January 2017, Wiley

    Dr James R Wheeler

  7. Reducing the number of fish in regulatory bioconcentration testing: Identifying and overcoming the barriers to using the 1-concentration approach

    Article • Integrated Environmental Assessment and Management, December 2016, Wiley

    Dr James R Wheeler

  8. Are all chemicals endocrine disruptors?

    Article • Integrated Environmental Assessment and Management, March 2016, Wiley

    Dr James R Wheeler

  9. Mind the gap: Concerns using endpoints from endocrine screening assays in risk assessment

    Article • Regulatory Toxicology and Pharmacology, August 2014, Elsevier

    Dr James R Wheeler

  10. An evaluation of fish early life stage tests for predicting reproductive and longer-term toxicity from plant protection product active substances

    Article • Environmental Toxicology and Chemistry, June 2014, Wiley

    Dr James R Wheeler

  11. Population relevance of toxicant mediated changes in sex ratio in fish: An assessment using an individual-based zebrafish (Danio rerio) model

    Article • Ecological Modelling, May 2014, Elsevier

    Dr James R Wheeler

  12. Application of the threshold approach for acute fish toxicity testing to plant protection products: A proposed framework

    Article • Chemosphere, February 2014, Elsevier

    Dr James R Wheeler

  13. Are acute and chronic saltwater fish studies required for plant protection and biocidal product active substance risk assessment?

    Article • Environmental Toxicology and Chemistry, January 2014, Wiley

    Dr James R Wheeler

  14. A European perspective on alternatives to animal testing for environmental hazard identification and risk assessment

    Article • Regulatory Toxicology and Pharmacology, December 2013, Elsevier

    Dr James R Wheeler

  15. Refinement of the ECETOC approach to identify endocrine disrupting properties of chemicals in ecotoxicology

    Article • Toxicology Letters, December 2013, Elsevier

    Dr James R Wheeler

  16. The use of carrier solvents in regulatory aquatic toxicology testing: Practical, statistical and regulatory considerations

    Article • Aquatic Toxicology, November 2013, Elsevier

    Dr James R Wheeler

  17. Test concentration setting for fish in vivo endocrine screening assays

    Article • Chemosphere, August 2013, Elsevier

    Dr James R Wheeler

  18. COMPARATIVE ACUTE AND CHRONIC SENSITIVITY OF FISH AND AMPHIBIANS: A CRITICAL REVIEW OF DATA

    Article • Environmental Toxicology and Chemistry, March 2013, Wiley

    Dr James R Wheeler

  19. A method to predict and understand fish survival under dynamic chemical stress using standard ecotoxicity data

    Article • Environmental Toxicology and Chemistry, March 2013, Wiley

    Dr James R Wheeler

  20. Reducing the number of fish in bioconcentration studies for plant protection products by reducing the number of test concentrations

    Article • Chemosphere, January 2013, Elsevier

    Dr James R Wheeler

  21. Density-Dependent Processes in the Life History of Fishes: Evidence from Laboratory Populations of Zebrafish Danio rerio

    Article • PLoS ONE, May 2012, PLOS

    Dr James R Wheeler

  22. Developments on the Regulation of Endocrine Disrupting Substances in Europe – Hazard, Risk and the Need for a Scientific Approach

    Article • Outlooks on Pest Management, April 2012, Research Information Ltd.

    Dr James R Wheeler

  23. Molecular and cellular effects of chemicals disrupting steroidogenesis during early ovarian development of brown trout (Salmo trutta fario)

    Article • Environmental Toxicology, November 2011, Wiley

    Dr James R Wheeler

  24. Mode of sexual differentiation and its influence on the relative sensitivity of the fathead minnow and zebrafish in the fish sexual development test

    Article • Aquatic Toxicology, October 2011, Elsevier

    Dr James R Wheeler

  25. Corrigendum to “Science based guidance for the assessment of endocrine disrupting properties of chemicals” [Regul. Toxicol. Pharmacol. 59 (2011) 37–46]

    Article • Regulatory Toxicology and Pharmacology, August 2011, Elsevier

    Dr James R Wheeler

  26. Science based guidance for the assessment of endocrine disrupting properties of chemicals

    Article • Regulatory Toxicology and Pharmacology, February 2011, Elsevier

    Dr James R Wheeler

  27. Development of an ex vivo brown trout (Salmo trutta fario) gonad culture for assessing chemical effects on steroidogenesis

    Article • Aquatic Toxicology, February 2011, Elsevier

    Dr James R Wheeler

  28. Ecotoxicology of Synthetic Pyrethroids

    Article • January 2011, Springer Science + Business Media

    Dr James R Wheeler

  29. Species extrapolation for the 21st century

    Article • Environmental Toxicology and Chemistry, November 2010, Wiley

    Dr James R Wheeler

  30. Challenging the requirement for chronic fish toxicity studies on formulated plant protection products

    Article • Toxicology Letters, November 2010, Elsevier

    Dr James R Wheeler

  31. Effects of a weak oestrogenic active chemical (4-tert-pentylphenol) on pair-breeding and F1 development in the fathead minnow (Pimephales promelas)

    Article • Aquatic Toxicology, May 2010, Elsevier

    Dr James R Wheeler

  32. Multi-criteria decision analysis of test endpoints for detecting the effects of endocrine active substances in fish full life cycle tests

    Article • Integrated Environmental Assessment and Management, January 2010, Wiley

    Dr James R Wheeler

  33. Thresholds of Toxicological Concern for Endocrine Active Substances in the Aquatic Environment

    Article • Integrated Environmental Assessment and Management, January 2007, Wiley

    Dr James R Wheeler

  34. THE CHIRONOMID ACUTE TOXICITY TEST: DEVELOPMENT OF A NEW TEST SYSTEM

    Article • Integrated Environmental Assessment and Management, January 2007, Wiley

    Dr James R Wheeler

  35. Vitellogenin: A Review of Analytical Methods to Detect (Anti) Estrogenic Activity in Fish

    Article • Toxicology Mechanisms and Methods, January 2005, Taylor & Francis

    Dr James R Wheeler

  36. Species sensitivity distributions: data and model choice

    Article • Marine Pollution Bulletin, September 2002, Elsevier

    Dr James R Wheeler

  37. Better bootstrap estimation of hazardous concentration thresholds for aquatic assemblages

    Article • Environmental Toxicology and Chemistry, July 2002, Wiley

    Dr James R Wheeler

  38. The comparison of rapid bioassays for the assessment of urban groundwater quality

    Article • Chemosphere, May 2002, Elsevier

    Dr James R Wheeler

  39. FRESHWATER TO SALTWATER TOXICITY EXTRAPOLATION USING SPECIES SENSITIVITY DISTRIBUTIONS

    Article • Environmental Toxicology and Chemistry, January 2002, Wiley

    Dr James R Wheeler

  40. Can Saltwater Toxicity be Predicted from Freshwater Data?

    Article • Marine Pollution Bulletin, November 2001, Elsevier

    Dr James R Wheeler

  41. European Approaches to Coastal and Estuarine Risk Assessment

    Article • September 2001, Taylor & Francis

    Dr James R Wheeler