All Stories

  1. Updates on the study of lysosomal protein dynamics: possibilities for the clinic

    Article • Expert Review of Proteomics, March 2023, Taylor & Francis

    Dr Dominic Winter

  2. Multi–Cell Line Analysis of Lysosomal Proteomes Reveals Unique Features and Novel Lysosomal Proteins

    Article • Molecular & Cellular Proteomics, March 2023, Elsevier

    Dr Dominic Winter

  3. The mitochondrial Hsp70 controls the assembly of the F1FO-ATP synthase

    Article • Nature Communications, January 2023, Springer Science + Business Media

    Dr Dominic Winter

  4. Sphingolipid subtypes differentially control proinsulin processing and systemic glucose homeostasis

    Article • Nature Cell Biology, December 2022, Springer Science + Business Media

    Dr Dominic Winter

  5. Cross-linking of the endolysosomal system reveals potential flotillin structures and cargo

    Article • Nature Communications, October 2022, Springer Science + Business Media

    Dr Dominic Winter

  6. The human disease gene LYSET is essential for lysosomal enzyme transport and viral infection

    Article • Science, October 2022, American Association for the Advancement of Science

    Dr Dominic Winter

  7. Study on Tissue Homogenization Buffer Composition for Brain Mass Spectrometry-Based Proteomics

    Article • Biomedicines, October 2022, MDPI AG

    Dr Dominic Winter

  8. Age-Dependent Increase in Schmidt-Lanterman Incisures and a Cadm4-Associated Membrane Skeletal Complex in Fatty Acid 2-hydroxylase Deficient Mice: a Mouse Model of Spastic Paraplegia SPG35

    Article • Molecular Neurobiology, April 2022, Springer Science + Business Media

    Dr Dominic Winter

  9. Surveying the mitochondrial proteome

    Article • Nature Cell Biology, December 2021, Springer Science + Business Media

    Dr Dominic Winter

  10. Pathogenic variants in GNPTAB and GNPTG encoding distinct subunits of GlcNAc-1-phosphotransferase differentially impact bone resorption in patients with mucolipidosis type II and III

    Article • Genetics in Medicine, December 2021, Elsevier

    Dr Dominic Winter

  11. Effect of modulating glutamate signaling on myelinating oligodendrocytes and their development—A study in the zebrafish model

    Article • Journal of Neuroscience Research, September 2021, Wiley

    Dr Dominic Winter

  12. RapiGest precipitation depends on peptide concentration

    Article • PROTEOMICS, September 2021, Wiley

    Dr Dominic Winter

  13. Proteomic Analysis of Niemann-Pick Type C Hepatocytes Reveals Potential Therapeutic Targets for Liver Damage

    Article • Cells, August 2021, MDPI AG

    Dr Dominic Winter

  14. Generation of Antibodies Targeting Cleavable Cross-Linkers

    Article • Analytical Chemistry, February 2021, American Chemical Society (ACS)

    Dr Dominic Winter

  15. Targeted Quantification of the Lysosomal Proteome in Complex Samples

    Article • Proteomes, January 2021, MDPI AG

    Dr Dominic Winter

  16. A proteomic view on lysosomes

    Article • Molecular Omics, January 2021, Royal Society of Chemistry

    Dr Dominic Winter

  17. Multi cell line analysis of lysosomal proteomes reveals unique features and novel lysosomal proteins

    Article • December 2020, Cold Spring Harbor Laboratory Press

    Dr Dominic Winter

  18. Decreased turnover of the CNS myelin protein Opalin in a mouse model of hereditary spastic paraplegia 35

    Article • Human Molecular Genetics, November 2020, Oxford University Press (OUP)

    Dr Dominic Winter

  19. c-Abl Inhibition Activates TFEB and Promotes Cellular Clearance in a Lysosomal Disorder

    Article • iScience, November 2020, Elsevier

    Dr Dominic Winter

  20. Proteaphagy in Mammalian Cells Can Function Independent of ATG5/ATG7

    Article • Molecular & Cellular Proteomics, July 2020, Elsevier

    Dr Dominic Winter

  21. Comprehensive draft of the mouse embryonic fibroblast lysosomal proteome by mass spectrometry based proteomics

    Article • Scientific Data, February 2020, Springer Science + Business Media

    Dr Dominic Winter

  22. Identification of Antifungal Intracellular Proteins of Endophytic Bacillus pumilus by LC–MS/MS Analysis

    Article • International Journal of Peptide Research and Therapeutics, February 2020, Springer Science + Business Media

    Dr Dominic Winter

  23. Systematic Comparison of Strategies for the Enrichment of Lysosomes by Data Independent Acquisition

    Article • Journal of Proteome Research, November 2019, American Chemical Society (ACS)

    Dr Dominic Winter

  24. Muscle regulates mTOR dependent axonal local translation in motor neurons via CTRP3 secretion: implications for a neuromuscular disorder, spinal muscular atrophy

    Article • Acta Neuropathologica Communications, October 2019, Springer Science + Business Media

    Dr Dominic Winter

  25. Investigation of Oligodendrocyte Precursor Cell Differentiation by Quantitative Proteomics

    Article • PROTEOMICS, July 2019, Wiley

    Dr Dominic Winter

  26. A mouse model for SPG48 reveals a block of autophagic flux upon disruption of adaptor protein complex five

    Article • Neurobiology of Disease, July 2019, Elsevier

    Dr Dominic Winter

  27. Identification of Unexpected Protein Modifications by Mass Spectrometry-Based Proteomics

    Article • October 2018, Springer Science + Business Media

    Dr Dominic Winter

  28. Lysosomal Proteome and Secretome Analysis Identifies Missorted Enzymes and Their Nondegraded Substrates in Mucolipidosis III Mouse Cells

    Article • Molecular & Cellular Proteomics, August 2018, Elsevier

    Dr Dominic Winter

  29. Identification of Poly(ethylene glycol) and Poly(ethylene glycol)-Based Detergents Using Peptide Search Engines

    Article • Analytical Chemistry, May 2018, American Chemical Society (ACS)

    Dr Dominic Winter

  30. Tip-Based Fractionation of Batch-Enriched Phosphopeptides Facilitates Easy and Robust Phosphoproteome Analysis

    Article • Journal of Proteome Research, November 2017, American Chemical Society (ACS)

    Dr Dominic Winter

  31. A Comprehensive High-Resolution Targeted Workflow for the Deep Profiling of Sphingolipids

    Article • Analytical Chemistry, November 2017, American Chemical Society (ACS)

    Dr Dominic Winter

  32. Systematic Evaluation of Protein Reduction and Alkylation Reveals Massive Unspecific Side Effects by Iodine-containing Reagents

    Article • Molecular & Cellular Proteomics, July 2017, Elsevier

    Dr Dominic Winter

  33. SILAC-Based Comparative Proteomic Analysis of Lysosomes from Mammalian Cells Using LC-MS/MS

    Article • January 2017, Springer Science + Business Media

    Dr Dominic Winter

  34. In vitro antihistamine-releasing activity of a peptide derived from wasp venom of Vespa orientalis

    Article • Asian Pacific Journal of Tropical Biomedicine, March 2016, Medknow

    Dr Dominic Winter

  35. Multifunctional Thioredoxin-Like Protein from the Gastrointestinal Parasitic NematodesStrongyloides rattiandTrichuris suisAffects Mucosal Homeostasis

    Article • Journal of Parasitology Research, January 2016, Hindawi Publishing Corporation

    Dr Dominic Winter

  36. [Sec-to-Cys]selenoprotein – a novel type of recombinant, full-length selenoprotein standard for quantitative proteomics

    Article • Journal of Analytical Atomic Spectrometry, January 2016, Royal Society of Chemistry

    Dr Dominic Winter

  37. Anti-inflammatory activity of low molecular weight polysialic acid on human macrophages

    Article • Scientific Reports, November 2015, Springer Science + Business Media

    Dr Dominic Winter

  38. Optimization of Cell Lysis and Protein Digestion Protocols for Protein Analysis by LC-MS/MS

    Article • January 2015, Springer Science + Business Media

    Dr Dominic Winter

  39. Quantitative profiling of peptides from RNAs classified as noncoding

    Article • Nature Communications, November 2014, Springer Science + Business Media

    Dr Dominic Winter

  40. Co-regulation proteomics reveals substrates and mechanisms of APC/C-dependent degradation

    Article • The EMBO Journal, February 2014, Wiley

    Dr Dominic Winter

  41. Molecular interaction of artemisinin with translationally controlled tumor protein (TCTP) of Plasmodium falciparum

    Article • Biochemical Pharmacology, January 2013, Elsevier

    Dr Dominic Winter

  42. Enzyme-cleavable tandem peptides for quantitative studies in MS-based proteomics

    Article • PROTEOMICS, November 2012, Wiley

    Dr Dominic Winter

  43. Overcoming Species Boundaries in Peptide Identification with Bayesian Information Criterion-driven Error-tolerant Peptide Search (BICEPS)

    Article • Molecular & Cellular Proteomics, July 2012, Elsevier

    Dr Dominic Winter

  44. FLEXIQinase, a mass spectrometry–based assay, to unveil multikinase mechanisms

    Article • Nature Methods, April 2012, Springer Science + Business Media

    Dr Dominic Winter

  45. Pleiotropic effects of miR-183~96~182 converge to regulate cell survival, proliferation and migration in medulloblastoma

    Article • Acta Neuropathologica, March 2012, Springer Science + Business Media

    Dr Dominic Winter

  46. Optimization of cell lysis and protein digestion protocols for the analysis of HeLa S3 cells by LC-MS/MS

    Article • PROTEOMICS, November 2011, Wiley

    Dr Dominic Winter

  47. PINK1 and Parkin Target Miro for Phosphorylation and Degradation to Arrest Mitochondrial Motility

    Article • Cell, November 2011, Elsevier

    Dr Dominic Winter

  48. Design principles for information processing through signalling networks

    Article • Journal of Biotechnology, November 2010, Elsevier

    Dr Dominic Winter

  49. Structural and mechanistic information on c1 ion formation in collision-induced fragmentation of peptides

    Article • Journal of the American Society for Mass Spectrometry, October 2010, American Chemical Society (ACS)

    Dr Dominic Winter

  50. Metal ion-mobilizing additives for comprehensive detection of femtomole amounts of phosphopeptides by reversed phase LC-MS

    Article • Amino Acids, June 2010, Springer Science + Business Media

    Dr Dominic Winter

  51. Recombinant Isotope Labeled and Selenium Quantified Proteins for Absolute Protein Quantification

    Article • Analytical Chemistry, March 2010, American Chemical Society (ACS)

    Dr Dominic Winter

  52. Minimally permutated peptide analogs as internal standards for relative and absolute quantification of peptides and proteins

    Article • PROTEOMICS, January 2010, Wiley

    Dr Dominic Winter

  53. Theoretical and experimental analysis links isoform- specific ERK signalling to cell fate decisions

    Article • Molecular Systems Biology, December 2009, EMBO

    Dr Dominic Winter

  54. When less can yield more - Computational preprocessing of MS/MS spectra for peptide identification

    Article • PROTEOMICS, November 2009, Wiley

    Dr Dominic Winter

  55. Protein phosphorylation influences proteolytic cleavage and kinase substrate properties exemplified by analysis of in vitro phosphorylated Plasmodium falciparum glideosome-associated protein 45 by nano-ultra performance liquid chromatography–tandem mas...

    Article • Analytical Biochemistry, October 2009, Elsevier

    Dr Dominic Winter

  56. Phosphorylation of CARMA1 by HPK1 is critical for NF-κB activation in T cells

    Article • Proceedings of the National Academy of Sciences, August 2009, Proceedings of the National Academy of Sciences

    Dr Dominic Winter

  57. Sequencing of the thirteen structurally isomeric quartets of N-terminal dipeptide motifs in peptides by collision-induced dissociation

    Article • PROTEOMICS, April 2009, Wiley

    Dr Dominic Winter

  58. Separation of peptide isomers and conformers by ultra performance liquid chromatography

    Article • Journal of Separation Science, April 2009, Wiley

    Dr Dominic Winter

  59. Individual b2 ion fragmentation profiles combined with AspN digestion improve N-terminal peptide sequencing

    Article • Analytical and Bioanalytical Chemistry, February 2009, Springer Science + Business Media

    Dr Dominic Winter

  60. Citrate Boosts the Performance of Phosphopeptide Analysis by UPLC-ESI-MS/MS

    Article • Journal of Proteome Research, January 2009, American Chemical Society (ACS)

    Dr Dominic Winter

  61. Raf kinase inhibitor protein affects activity of Plasmodium falciparum calcium-dependent protein kinase 1

    Article • Molecular and Biochemical Parasitology, January 2007, Elsevier

    Dr Dominic Winter