All Stories

  1. Effect of the side chain spacer structure on the pH-responsive properties of polycarboxylates

    Article • Journal of Biomaterials Science Polymer Edition, May 2017, Taylor & Francis

    Dr Atsushi Harada

  2. Gene expression of ternary complexes through the compaction of nanofiber-polyplexes by mixing with lipofectamine

    Article • Biomaterials Science, January 2015, Royal Society of Chemistry

    Dr Atsushi Harada

  3. Intracellular Delivery II

    Article • January 2014

    Dr Atsushi Harada

  4. Preparation of amphiphilic diblock copolymers with pendant hydrophilic phosphorylcholine and hydrophobic dendron groups and their self-association behavior in water

    Article • Journal of Polymer Science Part A Polymer Chemistry, September 2013, Wiley

    Dr Atsushi Harada

  5. Titanium dioxide nanoparticle-entrapped polyion complex micelles generate singlet oxygen in the cells by ultrasound irradiation for sonodynamic therapy

    Article • Biomaterials Science, January 2013, Royal Society of Chemistry

    Dr Atsushi Harada

  6. Block copolymer micelles for drug delivery: Design, characterization and biological significance

    Article • Advanced Drug Delivery Reviews, December 2012, Elsevier

    Dr Atsushi Harada

  7. Hollow nanocapsules prepared through stabilization of polymer vesicles formed from head–tail type polycations by introducing cross-linkages

    Article • Soft Matter, January 2011, Royal Society of Chemistry

    Dr Atsushi Harada

  8. Cationic Polymers with Inhibition Ability of DNA Condensation Elevate Gene Expression

    Article • ChemBioChem, August 2010, Wiley

    Dr Atsushi Harada

  9. Effective Tolerance to Serum Proteins of Head−Tail Type Polycation Vectors by PEGylation at the Periphery of the Head Block

    Article • Biomacromolecules, April 2010, American Chemical Society (ACS)

    Dr Atsushi Harada

  10. Effect of Head Size in Head-Tail-Type Polycations on theirin vitroPerformances as Nonviral Gene Vectors

    Article • Macromolecular Bioscience, June 2009, Wiley

    Dr Atsushi Harada

  11. Spontaneous formation of narrowly-distributed self-assembly from polyamidoamine dendron-poly(L-lysine) block copolymers through helix-coil transition of poly(L-lysine) block

    Article • Journal of Polymer Science Part A Polymer Chemistry, February 2009, Wiley

    Dr Atsushi Harada

  12. Polyion Complex Micelles

    Article • November 2008, Taylor & Francis

    Dr Atsushi Harada

  13. Selection between block- and homo-polyelectrolytes through polyion complex formation in aqueous medium

    Article • Soft Matter, January 2008, Royal Society of Chemistry

    Dr Atsushi Harada

  14. Polyion complex micelles formed from glucose oxidase and comb-type polyelectrolyte with poly(ethylene glycol) grafts

    Article • Journal of Polymer Science Part A Polymer Chemistry, January 2008, Wiley

    Dr Atsushi Harada

  15. Self-Assembled Nano-Bioreactor from Block Ionomers with Elevated and Stabilized Enzymatic Function

    Article • Bioconjugate Chemistry, September 2007, American Chemical Society (ACS)

    Dr Atsushi Harada

  16. Effect of Polycarboxylate Blocks on the Amidase Activity of Trypsin through Complexation with PEG/Polycarboxylate Block Ionomers

    Article • Macromolecular Bioscience, March 2007, Wiley

    Dr Atsushi Harada

  17. Preparation of temperature-responsive polymer gels physically immobilizing core-shell type bioconjugates

    Article • Journal of Polymer Science Part A Polymer Chemistry, January 2007, Wiley

    Dr Atsushi Harada

  18. Supramolecular assemblies of block copolymers in aqueous media as nanocontainers relevant to biological applications

    Article • Progress in Polymer Science, November 2006, Elsevier

    Dr Atsushi Harada

  19. Synthesis and Characterization of a Head−Tail Type Polycation Block Copolymer as a Nonviral Gene Vector

    Article • Bioconjugate Chemistry, January 2006, American Chemical Society (ACS)

    Dr Atsushi Harada

  20. Stabilization of Lysozyme-Incorporated Polyion Complex Micelles by the ω-End Derivatization of Poly(ethylene glycol)−Poly(α,β-aspartic acid) Block Copolymers with Hydrophobic Groups

    Article • Langmuir, March 2005, American Chemical Society (ACS)

    Dr Atsushi Harada

  21. Polyion Complex Micelles

    Article • March 2004, Taylor & Francis

    Dr Atsushi Harada

  22. Preparation of Bionanoreactor Based on Core−Shell Structured Polyion Complex Micelles Entrapping Trypsin in the Core Cross-Linked with Glutaraldehyde

    Article • Bioconjugate Chemistry, March 2004, American Chemical Society (ACS)

    Dr Atsushi Harada

  23. Switching by Pulse Electric Field of the Elevated Enzymatic Reaction in the Core of Polyion Complex Micelles

    Article • Journal of the American Chemical Society, December 2003, American Chemical Society (ACS)

    Dr Atsushi Harada

  24. Polyion complex micelles from plasmid DNA and poly(ethylene glycol)–poly(l-lysine) block copolymer as serum-tolerable polyplex system: physicochemical properties of micelles relevant to gene transfection efficiency

    Article • Biomaterials, November 2003, Elsevier

    Dr Atsushi Harada

  25. Effect of Charged Segment Length on Physicochemical Properties of Core−Shell Type Polyion Complex Micelles from Block Ionomers

    Article • Macromolecules, July 2003, American Chemical Society (ACS)

    Dr Atsushi Harada

  26. pH-sensitive Assembly of Light-Harvesting Dendrimer Zinc Porphyrin Bearing Peripheral Groups of Primary Amine with Poly(ethylene glycol)-b-poly(aspartic acid) in Aqueous Solution

    Article • Macromolecules, February 2003, American Chemical Society (ACS)

    Dr Atsushi Harada

  27. Evaluation by Fluorescence Resonance Energy Transfer of the Stability of Nonviral Gene Delivery Vectors under Physiological Conditions

    Article • Biomacromolecules, July 2002, American Chemical Society (ACS)

    Dr Atsushi Harada

  28. Polyion complex micelles with core-shell structure: their physicochemical properties and utilities as functional materials

    Article • Macromolecular Symposia, July 2001, Wiley

    Dr Atsushi Harada

  29. Glutathione-Sensitive Stabilization of Block Copolymer Micelles Composed of Antisense DNA and Thiolated Poly(ethylene glycol)- b lock -poly( l -lysine):  A Potential Carrier for Systemic Delivery of Antisense DNA

    Article • Biomacromolecules, June 2001, American Chemical Society (ACS)

    Dr Atsushi Harada

  30. Synthesis of Poly(ethylene glycol)- block -poly(ethylenimine) Possessing an Acetal Group at the PEG End

    Article • Macromolecules, August 2000, American Chemical Society (ACS)

    Dr Atsushi Harada

  31. Polyion Complex Micelles with Reactive Aldehyde Groups on Their Surface from Plasmid DNA and End-Functionalized Charged Block Copolymers

    Article • Macromolecules, October 1999, American Chemical Society (ACS)

    Dr Atsushi Harada

  32. On−Off Control of Enzymatic Activity Synchronizing with Reversible Formation of Supramolecular Assembly from Enzyme and Charged Block Copolymers

    Article • Journal of the American Chemical Society, October 1999, American Chemical Society (ACS)

    Dr Atsushi Harada

  33. Novel Polyion Complex Micelles Entrapping Enzyme Molecules in the Core. 2. Characterization of the Micelles Prepared at Nonstoichiometric Mixing Ratios †

    Article • Langmuir, June 1999, American Chemical Society (ACS)

    Dr Atsushi Harada

  34. Effect of the Secondary Structure of Poly( l -lysine) Segments on the Micellization in Aqueous Milieu of Poly(ethylene glycol)−Poly( l -lysine) Block Copolymer Partially Substituted with a Hydrocinnamoyl Group at the N ε -Position

    Article • Macromolecules, September 1998, American Chemical Society (ACS)

    Dr Atsushi Harada

  35. Novel Polyion Complex Micelles Entrapping Enzyme Molecules in the Core:  Preparation of Narrowly-Distributed Micelles from Lysozyme and Poly(ethylene glycol)−Poly(aspartic acid) Block Copolymer in Aqueous Medium

    Article • Macromolecules, January 1998, American Chemical Society (ACS)

    Dr Atsushi Harada

  36. Formation of Stable and Monodispersive Polyion Complex Micelles in Aqueous Medium from Poly(L-lysine) And Poly(Ethylene Glycol)-Poly(Aspartic Acid) Block Copolymer

    Article • Journal of Macromolecular Science Part A, October 1997, Taylor & Francis

    Dr Atsushi Harada

  37. Spontaneous Formation of Polyion Complex Micelles with Narrow Distribution from Antisense Oligonucleotide and Cationic Block Copolymer in Physiological Saline

    Article • Macromolecules, January 1996, American Chemical Society (ACS)

    Dr Atsushi Harada

  38. Formation of core-shell type nano-associates through electrostatic interaction between peptide and block copolymer with poly(ethylene glycol) segment

    Article • January 1996, Springer Science + Business Media

    Dr Atsushi Harada

  39. Stabilized α-Helix Structure of Poly( l -lysine)- block -poly(ethylene glycol) in Aqueous Medium through Supramolecular Assembly

    Article • Macromolecules, January 1996, American Chemical Society (ACS)

    Dr Atsushi Harada

  40. Formation of Polyion Complex Micelles in an Aqueous Milieu from a Pair of Oppositely-Charged Block Copolymers with Poly(ethylene glycol) Segments

    Article • Macromolecules, July 1995, American Chemical Society (ACS)

    Dr Atsushi Harada