All Stories

  1. ArcA overexpression induces fermentation and results in enhanced growth rates of E. coli

    Article • Scientific Reports, September 2017, Nature

    Professor James R Williamson

  2. Addressing preferred specimen orientation in single-particle cryo-EM through tilting

    Article • Nature Methods, July 2017, Nature

    Professor James R Williamson

  3. Structure and dynamics of bacterial ribosome biogenesis

    Article • Philosophical Transactions of the Royal Society B Biological Sciences, January 2017, Royal Society Publishing

    Professor James R Williamson

  4. Modular Assembly of the Bacterial Large Ribosomal Subunit

    Article • Cell, December 2016, Elsevier

    Professor James R Williamson

  5. YphC and YsxC GTPases assist the maturation of the central protuberance, GTPase associated region and functional core of the 50S ribosomal subunit

    Article • Nucleic Acids Research, August 2016, Oxford University Press (OUP)

    Professor James R Williamson

  6. Binding properties of YjeQ (RsgA), RbfA, RimM and Era to assembly intermediates of the 30S subunit

    Article • Nucleic Acids Research, July 2016, Oxford University Press (OUP)

    Professor James R Williamson

  7. FRET Characterization of Complex Conformational Changes in a Large 16S Ribosomal RNA Fragment Site-Specifically Labeled Using Unnatural Base Pairs

    Article • ACS Chemical Biology, May 2016, American Chemical Society (ACS)

    Professor James R Williamson

  8. The acidic domain is a unique structural feature of the splicing factor SYNCRIP

    Article • Protein Science, May 2016, Wiley

    Professor James R Williamson

  9. UHM–ULM interactions in the RBM39–U2AF65 splicing-factor complex

    Article • Acta Crystallographica Section D Structural Biology, March 2016, International Union of Crystallography

    Professor James R Williamson

  10. The Activation-Induced Assembly of an RNA/Protein Interactome Centered on the Splicing Factor U2AF2 Regulates Gene Expression in Human CD4 T Cells

    Article • PLoS ONE, December 2015, PLOS

    Professor James R Williamson

  11. Overflow metabolism in Escherichia coli results from efficient proteome allocation

    Article • Nature, December 2015, Nature

    Professor James R Williamson

  12. Toward a Whole-Cell Model of Ribosome Biogenesis: Kinetic Modeling of SSU Assembly

    Article • Biophysical Journal, September 2015, Elsevier

    Professor James R Williamson

  13. Measuring Food Intake and Nutrient Absorption in Caenorhabditis elegans

    Article • Genetics, April 2015, Genetics Society of America

    Professor James R Williamson

  14. Quantitative proteomic analysis reveals a simple strategy of global resource allocation in bacteria

    Article • Molecular Systems Biology, February 2015, EMBO

    Professor James R Williamson, Terence Hwa

  15. R eally e xasperating v iral protein from HIV

    Article • eLife, January 2015, eLife

    Professor James R Williamson

  16. Functional Interaction between Ribosomal Protein L6 and RbgA during Ribosome Assembly

    Article • PLoS Genetics, October 2014, PLOS

    Dr Joseph H Davis, Professor James R Williamson

  17. A combined quantitative mass spectrometry and electron microscopy analysis of ribosomal 30S subunit assembly in E. coli

    Article • eLife, October 2014, eLife

    Professor James R Williamson

  18. Discovery of a small molecule that inhibits bacterial ribosome biogenesis

    Article • eLife, September 2014, eLife

    Professor Eric D Brown, Mr Jonathan M Stokes, Dr Joseph H Davis, Professor James R Williamson

  19. Quantitative Analysis of rRNA Modifications Using Stable Isotope Labeling and Mass Spectrometry

    Article • Journal of the American Chemical Society, February 2014, American Chemical Society (ACS)

    Professor James R Williamson

  20. Functional domains of the 50S subunit mature late in the assembly process

    Article • Nucleic Acids Research, December 2013, Oxford University Press (OUP)

    Dr Joseph H Davis, Professor James R Williamson

  21. Vectorized data acquisition and fast triple-correlation integrals for Fluorescence Triple Correlation Spectroscopy

    Article • Computer Physics Communications, April 2013, Elsevier

    Professor James R Williamson

  22. Biochemical Characterization of the Caenorhabditis elegans FBF⋅CPB-1 Translational Regulation Complex Identifies Conserved Protein Interaction Hotspots

    Article • Journal of Molecular Biology, February 2013, Elsevier

    Professor James R Williamson

  23. Characterization of the Ribosome Biogenesis Landscape in E. coli Using Quantitative Mass Spectrometry

    Article • Journal of Molecular Biology, February 2013, Elsevier

    Professor James R Williamson

  24. A Protein⋅Protein Interaction Platform Involved in Recruitment of GLD-3 to the FBF⋅fem-3 mRNA Complex

    Article • Journal of Molecular Biology, February 2013, Elsevier

    Professor James R Williamson

  25. Structural Analysis of the Quaking Homodimerization Interface

    Article • Journal of Molecular Biology, November 2012, Elsevier

    Professor James R Williamson

  26. Quantitation of ten 30S ribosomal assembly intermediates using fluorescence triple correlation spectroscopy

    Article • Proceedings of the National Academy of Sciences, August 2012, Proceedings of the National Academy of Sciences

    Professor James R Williamson

  27. Cooperativity in RNA-Protein Interactions: Global Analysis of RNA Binding Specificity

    Article • Cell Reports, May 2012, Elsevier

    Professor James R Williamson

  28. Identification of a Conserved Interface between PUF and CPEB Proteins

    Article • Journal of Biological Chemistry, April 2012, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor James R Williamson

  29. The Spectroscopic Basis of Fluorescence Triple Correlation Spectroscopy

    Article • The Journal of Physical Chemistry, February 2012, American Chemical Society (ACS)

    Professor James R Williamson

  30. Measuring the dynamics of E. coli ribosome biogenesis using pulse-labeling and quantitative mass spectrometry

    Article • Molecular BioSystems, January 2012, Royal Society of Chemistry

    Dr Joseph H Davis, Professor James R Williamson

  31. The Structure of Aquifex aeolicus Ribosomal Protein S8 Reveals a Unique Subdomain that Contributes to an Extremely Tight Association with 16S rRNA

    Article • Journal of Molecular Biology, January 2012, Elsevier

    Professor James R Williamson

  32. DDX1 Is an RNA-Dependent ATPase Involved in HIV-1 Rev Function and Virus Replication

    Article • Journal of Molecular Biology, January 2012, Elsevier

    Professor James R Williamson

  33. The Structure of the NXF2/NXT1 Heterodimeric Complex Reveals the Combined Specificity and Versatility of the NTF2-Like Fold

    Article • Journal of Molecular Biology, January 2012, Elsevier

    Professor James R Williamson

  34. Systematic Chromosomal Deletion of Bacterial Ribosomal Protein Genes

    Article • Journal of Molecular Biology, November 2011, Elsevier

    Professor James R Williamson

  35. Single-Molecule Studies Reveal that DEAD Box Protein DDX1 Promotes Oligomerization of HIV-1 Rev on the Rev Response Element

    Article • Journal of Molecular Biology, July 2011, Elsevier

    Professor James R Williamson

  36. Enzymatic De Novo Pyrimidine Nucleotide Synthesis

    Article • Journal of the American Chemical Society, January 2011, American Chemical Society (ACS)

    Professor James R Williamson

  37. Visualizing Ribosome Biogenesis: Parallel Assembly Pathways for the 30S Subunit

    Article • Science, October 2010, American Association for the Advancement of Science

    Professor James R Williamson

  38. Quantitative Proteomic Analysis of Ribosome Assembly and Turnover In Vivo

    Article • Journal of Molecular Biology, October 2010, Elsevier

    Professor James R Williamson

  39. Quantitation of the Ribosomal Protein Autoregulatory Network Using Mass Spectrometry

    Article • Analytical Chemistry, June 2010, American Chemical Society (ACS)

    Professor James R Williamson

  40. Nucleic acids continue to surprise

    Article • Current Opinion in Structural Biology, June 2010, Elsevier

    Professor James R Williamson

  41. The Effect of Ribosome Assembly Cofactors on In Vitro 30S Subunit Reconstitution

    Article • Journal of Molecular Biology, April 2010, Elsevier

    Professor James R Williamson

  42. Kinetic cooperativity in Escherichia coli 30S ribosomal subunit reconstitution reveals additional complexity in the assembly landscape

    Article • Proceedings of the National Academy of Sciences, March 2010, Proceedings of the National Academy of Sciences

    Professor James R Williamson

  43. Structure of the GLD-1 Homodimerization Domain: Insights into STAR Protein-Mediated Translational Regulation

    Article • Structure, March 2010, Elsevier

    Professor James R Williamson

  44. High-affinity consensus binding of target RNAs by the STAR/GSG proteins GLD-1, STAR-2 and Quaking

    Article • BMC Molecular Biology, January 2010, Springer Science + Business Media

    Professor James R Williamson

  45. The Ribosome at Atomic Resolution

    Article • Cell, December 2009, Elsevier

    Professor James R Williamson

  46. Enzymatic Synthesis and Structural Characterization of 13 C, 15 N-Poly(ADP-ribose)

    Article • Journal of the American Chemical Society, October 2009, American Chemical Society (ACS)

    Professor James R Williamson

  47. Stable isotope pulse-chase monitored by quantitative mass spectrometry applied to E. coli 30S ribosome assembly kinetics

    Article • Methods, October 2009, Elsevier

    Professor James R Williamson

  48. RNA-protein binding kinetics in an automated microfluidic reactor

    Article • Nucleic Acids Research, September 2009, Oxford University Press (OUP)

    Professor James R Williamson

  49. A dominant negative mutant of the E. coli RNA helicase DbpA blocks assembly of the 50S ribosomal subunit

    Article • Nucleic Acids Research, September 2009, Oxford University Press (OUP)

    Professor James R Williamson

  50. A Complex Assembly Landscape for the 30S Ribosomal Subunit

    Article • Annual Review of Biophysics, June 2009, Annual Reviews

    Professor James R Williamson

  51. My h -index Turns 40: My Midlife Crisis of Impact

    Article • ACS Chemical Biology, May 2009, American Chemical Society (ACS)

    Professor James R Williamson

  52. Synergy of NMR, Computation, and X-Ray Crystallography for Structural Biology

    Article • Structure, April 2009, Elsevier

    Professor James R Williamson

  53. The universal YrdC/Sua5 family is required for the formation of threonylcarbamoyladenosine in tRNA

    Article • Nucleic Acids Research, March 2009, Oxford University Press (OUP)

    Professor James R Williamson

  54. Solution NMR Studies of the Maturation Intermediates of a 13 MDa Viral Capsid

    Article • Journal of the American Chemical Society, June 2007, American Chemical Society (ACS)

    Professor James R Williamson

  55. A Higher Degree of Difficulty

    Article • ACS Chemical Biology, April 2007, American Chemical Society (ACS)

    Professor James R Williamson