All Stories

  1. Current Trends and Future Approaches in Small-Molecule Therapeutics for COVID-19
  2. Antimicrobial molecules in the lung: formulation challenges and future directions for innovation
  3. Current Advances in Developing Inhibitors of Bacterial Multidrug Efflux Pumps
  4. Novel 1-(2-aryl-2-adamantyl)piperazine derivatives with antiproliferative activity
  5. Crispene E, a cis-clerodane diterpene inhibits STAT3 dimerization in breast cancer cells
  6. Effect of hairpin loop structure on reactivity, sequence preference and adduct orientation of a DNA-interactive pyrrolo[2,1-c][1,4]benzodiazepine (PBD) antitumour agent
  7. Computational Studies Support the Role of the C7-Sibirosamine Sugar of the Pyrrolobenzodiazepine (PBD) Sibiromycin in Transcription Factor Inhibition
  8. Pyrrolobenzodiazepines (PBDs) Do Not Bind to DNA G-Quadruplexes
  9. Investigation of the protein alkylation sites of the STAT3:STAT3 inhibitor Stattic by mass spectrometry
  10. GC-Targeted C8-Linked Pyrrolobenzodiazepine–Biaryl Conjugates with Femtomolar in Vitro Cytotoxicity and in Vivo Antitumor Activity in Mouse Models
  11. Observation of unphosphorylated STAT3 core protein binding to target dsDNA by PEMSA and X‐ray crystallography
  12. Identification of novel telomeric G-quadruplex-targeting chemical scaffolds through screening of three NCI libraries
  13. The prenylated dioxopiperazine alkaloid Cristatin A has selective telomeric DNA G-quadruplex stabilising properties
  14. Observation of a Single-Stranded DNA/Pyrrolobenzodiazepine Adduct
  15. Observation of the reversibility of a covalent pyrrolobenzodiazepine (PBD) DNA adduct by HPLC/MS and CD spectroscopy
  16. A novel small-molecule inhibitor of IL-6 signalling
  17. DNA Sequence Preference and Adduct Orientation of Pyrrolo[2,1- c ][1,4]benzodiazepine Antitumor Agents
  18. Binding of Betamethasone, Prednisolone and Theophylline to Bovine Serum Albumin: Plausible Explanations for Mode of Binding and Drug-drug Interactions
  19. The Pyrrolobenzodiazepine Dimer SJG-136 Forms Sequence-Dependent Intrastrand DNA Cross-Links and Monoalkylated Adducts in Addition to Interstrand Cross-Links
  20. Biaryl polyamides as a new class of DNA quadruplex-binding ligands
  21. Effect of microwave irradiation on covalent ligand–DNA interactions
  22. Observation of a dynamic equilibrium between DNA hairpin and duplex forms of covalent adducts of a minor groove binding agent
  23. Preliminary Cytotoxicity Screening of Some Medicinal Plants of Bangladesh
  24. Stereochenols A and B, Two Quinones from Stereospermum chelonoides.
  25. Stereochenols A and B, two quinones from Stereospermum chelonoides
  26. Binding of Betamethasone, Prednisolone and Theophylline to Bovine Serum Albumin: Plausible Explanations for Mode of Binding and Drug-drug Interactions
  27. Antibacterial activity and cytotoxicity of extractives from Ravenia spectabilis
  28. Cytotoxicity and antibacterial activity of extractives from Wedelia calendulacea
  29. Phytochemical Studies of Amoora cucullata
  30. Secondary Metabolites from Sterespermum chelonoides
  31. Antimicrobial and Cytotoxic activities of Stereospermum chelonoides