Current affiliation: ETH Zürich, D-CHABSubject: ChemistryPrimary location: Switzerland
Published in:Phosphorus Sulfur and Silicon and the Related ElementsPublication date:2015-03-20
Published in:Journal of Medicinal ChemistryPublication date:2015-04-09
Serine hydromethyltransferase (SHMT) has a crucial role in the folate pathway. We have shown for the first time that this enzyme is a valid target ...
Published in:Chemistry - A European JournalPublication date:2015-12-18
1,1,1,3,3,3-hexafluoroisopropanol (HFIP) was used as solvent for sulfoxide-directed oxidative olefination. The use of HFIP allowed to greatly impro...
Published in:ChemInformPublication date:2016-05-01
Published in:NanoscalePublication date:2016-01-01
Published in:Journal of Medicinal ChemistryPublication date:2017-06-13
A library of antimalarial active substances was developed through state-of-the-art structure-based design. Several series of inhibitors, targeting ...