All Stories

  1. Resistome Analysis of Klebsiella pneumoniae Complex from Residential Aged Care Facilities Demonstrates Intra-facility Clonal Spread of Multidrug-Resistant Isolates
  2. Identification and characterization of CIM-1, a carbapenemase that adds to the family of resistance factors against last resort antibiotics
  3. Identification and evolution of ICE-PmuST394: a novel integrative conjugative element in Pasteurella multocida ST394
  4. Recommendations of Key Elements within an Integrated Monitoring Framework of Antimicrobial Resistance for Asian Countries
  5. The scope of antimicrobial resistance in residential aged care facilities determined through analysis of Escherichia coli and the total wastewater resistome
  6. Orthogonal Reversed-Phase C18 and Pentafluorophenyl HPLC Separation for Phytochemical Profiling of Serrulatanes in Eremophila denticulata
  7. Combined Structure- and Ligand-Based Approach for the Identification of Inhibitors of AcrAB-TolC in Escherichia coli
  8. Oral administration of a 2-aminopyrimidine robenidine analogue (NCL195) significantly reduces Staphylococcus aureus infection and reduces Escherichia coli infection in combination with sub-i...
  9. Genomic profiling of Pasteurella multocida isolated from feedlot cases of bovine respiratory disease
  10. Adding to the family of resistance factors against last resort antibiotics: Identification and characterization of a novel carbapenemase, CIM-1
  11. Design and synthesis of benzochromene derivatives as AcrB inhibitors for the reversal of bacterial multidrug resistance
  12. Polypharmacology-Labeled Molecular Networking: An Analytical Technology Workflow for Accelerated Identification of Multiple Bioactive Constituents in Complex Extracts
  13. Targeting malaria parasites with novel derivatives of azithromycin
  14. In Vitro Activity of Robenidine Analogues NCL259 and NCL265 against Gram-Negative Pathogens
  15. Cinnamaldehyde derivatives act as antimicrobial agents against Acinetobacter baumannii through the inhibition of cell division
  16. Antimicrobial susceptibility and genomic analysis of Histophilus somni isolated from cases of bovine respiratory disease in Australian feedlot cattle
  17. Lacritin Bactericidal Peptide N‐104 Targeting of Inner Membrane Transporters FeoB and PotH (SpuG) Individually Absent in N‐104 Resistant Strains of Human Opportunistic Pathogen, P. aeruginosa PA14
  18. Correction: Alhamami et al. First Emergence of Resistance to Macrolides and Tetracycline Identified in Mannheimia haemolytica and Pasteurella multocida Isolates from Beef Feedlots in Australia. Microorganisms 2021, 9, 1322
  19. The Structural and Functional Study of Efflux Pumps Belonging to the RND Transporters Family from Gram-Negative Bacteria
  20. Complete Genome Sequence of Pasteurella multocida Sequence Type 394, Isolated from a Case of Bovine Respiratory Disease in Australia
  21. Impact of a Novel Anticoccidial Analogue on Systemic Staphylococcus aureus Infection in a Bioluminescent Mouse Model
  22. Worldwide distribution and environmental origin of the Adelaide imipenemase (AIM-1), a potent carbapenemase in Pseudomonas aeruginosa
  23. Bioactivity-guided isolation of compounds from Sophora flavescens with antibacterial activity against Acinetobacter baumannii
  24. An optimized and robust PEG precipitation method for detection of SARS-CoV-2 in wastewater
  25. Taking AIM-(1) at carbapenem resistance in Pseudomonas aeruginosa
  26. Repurposing of the Fasciolicide Triclabendazole to Treat Infections Caused by Staphylococcus spp. and Vancomycin-Resistant Enterococci
  27. SdiA, a Quorum-Sensing Regulator, Suppresses Fimbriae Expression, Biofilm Formation, and Quorum-Sensing Signaling Molecules Production in Klebsiella pneumoniae
  28. First Emergence of Resistance to Macrolides and Tetracycline Identified in Mannheimia haemolytica and Pasteurella multocida Isolates from Beef Feedlots in Australia
  29. Evaluation of Benzguinols as Next-Generation Antibiotics for the Treatment of Multidrug-Resistant Bacterial Infections
  30. Protective role of PhtD and its amino and carboxyl fragments against pneumococcal sepsis
  31. In vitro synergistic activity of NCL195 in combination with colistin against Gram-negative bacterial pathogens
  32. Comparison of Two Transmission Electron Microscopy Methods to Visualize Drug-Induced Alterations of Gram-Negative Bacterial Morphology
  33. Design and structural optimization of novel 2H-benzo[h]chromene derivatives that target AcrB and reverse bacterial multidrug resistance
  34. A pH-neutral electrolyzed oxidizing water significantly reduces microbial contamination of fresh spinach leaves
  35. Neutral electrolyzed oxidizing water is effective for pre-harvest decontamination of fresh produce
  36. Catecholic alkaloid sulfonates and aromatic nitro compounds from Portulaca oleracea and screening of their anti-inflammatory and anti-microbial activities
  37. Antimicrobial Action and Reversal of Resistance in MRSA by Difluorobenzamide Derivatives Targeted at FtsZ
  38. Design and synthesis of aryl-substituted pyrrolidone derivatives as quorum sensing inhibitors
  39. Design and synthesis of novel 4-substituted quinazoline-2-carboxamide derivatives targeting AcrB to reverse the bacterial multidrug resistance
  40. Efflux Pump-Driven Antibiotic and Biocide Cross-Resistance in Pseudomonas aeruginosa Isolated from Different Ecological Niches: A Case Study in the Development of Multidrug Resistance in Environmental Hotspots
  41. In vitro Activity of Robenidine Analog NCL195 in Combination With Outer Membrane Permeabilizers Against Gram-Negative Bacterial Pathogens and Impact on Systemic Gram-Positive Bacterial Infection in Mice
  42. Structural optimization of natural product nordihydroguaretic acid to discover novel analogues as AcrB inhibitors
  43. Comparative antibacterial activities of neutral electrolyzed oxidizing water and other chlorine-based sanitizers
  44. Disinfection options for irrigation water: Reducing the risk of fresh produce contamination with human pathogens
  45. Measuring Small Molecule Binding to Escherichia coli AcrB by Surface Plasmon Resonance
  46. Allicin prevents the formation of Proteus-induced urinary crystals and the blockage of catheter in a bladder model in vitro
  47. Antimicrobial effects of cinnamon essential oil and cinnamaldehyde combined with EDTA against canine otitis externa pathogens
  48. In vitro Antimicrobial Activity of Robenidine, Ethylenediaminetetraacetic Acid and Polymyxin B Nonapeptide Against Important Human and Veterinary Pathogens
  49. Reversing resistance to counter antimicrobial resistance in the World Health Organisation’s critical priority of most dangerous pathogens
  50. Design, synthesis and evaluation of a series of 5-methoxy-2,3-naphthalimide derivatives as AcrB inhibitors for the reversal of bacterial resistance
  51. Design, synthesis and structure-based optimization of novel isoxazole-containing benzamide derivatives as FtsZ modulators
  52. Induction of Escherichia coli into a VBNC state through chlorination/chloramination and differences in characteristics of the bacterium between states
  53. Bioluminescent murine models of bacterial sepsis and scald wound infections for antimicrobial efficacy testing
  54. Genomic characterization of coagulase-negative staphylococci including methicillin-resistant Staphylococcus sciuri causing bovine mastitis
  55. Novel 5-methyl-2-phenylphenanthridium derivatives as FtsZ-targeting antibacterial agents from structural simplification of natural product sanguinarine
  56. Kinetic analysis of the inhibition of the drug efflux protein AcrB using surface plasmon resonance
  57. Substitution of terminal amide with 1 H -1,2,3-triazole: Identification of unexpected class of potent antibacterial agents
  58. Design, synthesis and biological activity evaluation of novel 4-subtituted 2-naphthamide derivatives as AcrB inhibitors
  59. Efficacy evaluation of a new water sanitizer for increasing the shelf life of Southern Australian King George Whiting and Tasmanian Atlantic Salmon fillets
  60. Evaluation of robenidine analog NCL195 as a novel broad-spectrum antibacterial agent
  61. Synthesis and antibacterial activity of 5-methylphenanthridium derivatives as FtsZ inhibitors
  62. Antimicrobial resistance in healthcare, agriculture and the environment: the biochemistry behind the headlines
  63. Intrinsic, adaptive and acquired antimicrobial resistance in Gram-negative bacteria
  64. Design, synthesis and biological activity evaluation of novel 2,6-difluorobenzamide derivatives through FtsZ inhibition
  65. Evaluation of a series of 2-napthamide derivatives as inhibitors of the drug efflux pump AcrB for the reversal of antimicrobial resistance
  66. Synthesis and antibacterial activity of novel 3- O -descladinosylazithromycin derivatives
  67. Bio-augmentation and nutrient amendment decrease concentration of mercury in contaminated soil
  68. Structural model of FeoB, the iron transporter from Pseudomonas aeruginosa, predicts a cysteine lined, GTP-gated pore
  69. Efflux Pump Inhibitors: A Novel Approach to Combat Efflux-Mediated Drug Resistance in Bacteria
  70. Synthesis and Biological Evaluation of Novel FtsZ‐targeted 3‐arylalkoxy‐2,6‐difluorobenzamides as Potential Antimicrobial Agents
  71. RND-type drug efflux pumps from Gram-negative bacteria: molecular mechanism and inhibition
  72. Phytochemicals increase the antibacterial activity of antibiotics by acting on a drug efflux pump
  73. Expression, purification and functional reconstitution of FeoB, the ferrous iron transporter from Pseudomonas aeruginosa
  74. Structure of the AcrAB–TolC multidrug efflux pump
  75. Mutations in MexB that affect the efflux of antibiotics with cytoplasmic targets
  76. Promiscuous partnering and independent activity of MexB, the multidrug transporter protein from Pseudomonas aeruginosa
  77. A Multidrug ABC Transporter with a Taste for Salt
  78. Mass spectrometry of membrane transporters reveals subunit stoichiometry and interactions
  79. On the energy-dependence of Hoechst 33342 transport by the ABC transporter LmrA
  80. Two Proton Translocation Pathways in a Secondary Active Multidrug Transporter
  81. New light on multidrug binding by an ATP-binding-cassette transporter
  82. Similarities between ATP-dependent and ion-coupled multidrug transporters
  83. Drug-Lipid A Interactions on the Escherichia coli ABC Transporter MsbA
  84. A critical role of a carboxylate in proton conduction by the ATP‐binding cassette multidrug transporter LmrA
  85. Arginine-482 is not essential for transport of antibiotics, primary bile acids and unconjugated sterols by the human breast cancer resistance protein (ABCG2)
  86. Reversible Transport by the ATP-binding Cassette Multidrug Export Pump LmrA
  87. Purification and properties of theEscherichia colinucleoside transporter NupG, a paradigm for a major facilitator transporter sub-family
  88. An ABC transporter with a secondary-active multidrug translocator domain
  89. A new dimer interface for an ABC transporter
  90. The ATP Binding Cassette Multidrug Transporter LmrA and Lipid Transporter MsbA Have Overlapping Substrate Specificities
  91. Sterol Transport by the Human Breast Cancer Resistance Protein (ABCG2) Expressed in Lactococcus lactis
  92. Molecular dissection of membrane-transport proteins: mass spectrometry and sequence determination of the galactose‒H+ symport protein, GalP, of Escherichia coli and quantitative assay of the incorporation of [ring-2-13C]histidine and 15NH3
  93. Do mammals make their own morphine?
  94. Expression of prokaryotic membrane transport proteins in Escherichia coli
  95. Purification and Characterization of a Metalloprotease fromChryseobacterium indologenesIx9a and Determination of the Amino Acid Specificity with Electrospray Mass Spectrometry
  96. Equipping a Research Scale Fermentation Laboratory for Production of Membrane Proteins