Dr Carmen Valenzuela
Current affiliation: Instituto de Investigaciones Biomedicas Alberto Sols CSIC-UAM
Subject: Life Sciences
Primary location: Spain
Marine n-3 PUFAs modulate IKs gating, channel expression, and location in membrane microdomains
Published in:Cardiovascular Research
Publication date:2014-12-11
PKC inhibition results in a Kv1.5 + Kvβ1.3 pharmacology closer to Kv1.5 channels
Published in:British Journal of Pharmacology
Publication date:2014-09-05Kv1.5 + Kvβ1.3 pharmacology and PKC
Effects of propafenone and its main metabolite, 5-hydroxypropafenone, on HERG channels
Published in:Cardiovascular Research
Publication date:2003-03-01
Pharmacology of cardiac potassium channels
Published in:Cardiovascular Research
Publication date:2004-04-01
Interaction of angiotensin II with the angiotensin type 2 receptor inhibits the cardiac transient outward potassium current
Published in:Cardiovascular Research
Publication date:2004-04-01
Putative binding sites for benzocaine on a human cardiac cloned channel (Kv1.5)
Published in:Cardiovascular Research
Publication date:2002-10-01
Functional expression of an inactivating potassium channel (Kv4.3) in a mammalian cell line
Published in:Cardiovascular Research
Publication date:1999-01-01
Benzocaine enhances and inhibits the K+ current through a human cardiac cloned channel (Kv1.5)
Published in:Cardiovascular Research
Publication date:1999-05-01
Voltage-dependent Na+ channel phenotype changes in myoblasts. Consequences for cardiac repair☆
Published in:Cardiovascular Research
Publication date:2007-12-01
Pharmacological electrical remodelling in human atria induced by chronic β-blockade
Published in:Cardiovascular Research
Publication date:2003-06-01
Block of human cardiac Kv1.5 channels by loratadine: voltage-, time- and use-dependent block at concentrations above therapeutic levels
Published in:Cardiovascular Research
Publication date:1997-08-01
Female gender: risk factor for congenital long QT-related arrhythmias
Published in:Cardiovascular Research
Publication date:2012-06-21
New insights into the pharmacology of sodium channel blockers
Published in:European Heart Journal
Publication date:1992-11-02
Modulation of Voltage-Dependent and Inward Rectifier Potassium Channels by 15-Epi-Lipoxin-A4 in Activated Murine Macrophages: Implications in Innat...
Published in:The Journal of Immunology
Publication date:2013-11-18
Polyunsaturated Fatty Acids Modify the Gating of Kv Channels
Published in:Frontiers in Pharmacology
Publication date:2012-01-01
Effects of n−3 Polyunsaturated Fatty Acids on Cardiac Ion Channels
Published in:Frontiers in Physiology
Publication date:2012-01-01
Stereoselective Interactions between Local Anesthetics and Ion Channels
Published in:Chirality
Publication date:2012-06-07STEREOSELECTIVE DRUG-CHANNEL INTERACTIONS
Protein Kinase C (PKC) Activity Regulates Functional Effects of Kv 1.3 Subunit on KV1.5 Channels: IDENTIFICATION OF A CARDIAC Kv1.5 CHANNELOSOME
Published in:Journal of Biological Chemistry
Publication date:2012-04-30
Electrophysiological effects of CRE-1087 in guinea-pig ventricular muscles
Published in:British Journal of Pharmacology
Publication date:1992-10-01
Blockade of Cardiac Potassium and Other Channels by Antihistamines
Published in:Drug Safety
Publication date:1999-01-01
Differential Regulation Of Navß Subunits During Myogenesis
Published in:Biophysical Journal
Publication date:2009-02-01
Electrophysiological Effects of 5-Hydroxypropafenone on Guinea Pig Ventricular Muscle Fibres
Published in:Journal of Cardiovascular Pharmacology
Publication date:1987-11-01
Differential regulation of Navβ subunits during myogenesis
Published in:Biochemical and Biophysical Research Communications
Publication date:2008-04-01
Tonic and Phasic Vmax Block Induced by 5-Hydroxypropafenone in Guinea Pig Ventricular Muscles
Published in:Journal of Cardiovascular Pharmacology
Publication date:1988-10-01
Electrophysiologic Interactions Between Mexiletine and Propafenone in Guinea Pig Papillary Muscles
Published in:Journal of Cardiovascular Pharmacology
Publication date:1989-09-01
Tonic and Frequency-Dependent Vmax Block Induced by Imipramine in Guinea Pig Ventricular Muscle Fibers
Published in:Journal of Cardiovascular Pharmacology
Publication date:1990-03-01
Voltage- and Use-Dependent Modulation of Calcium Channel Current in Guinea Pig Ventricular Cells by Amiodarone and Des-Oxo-Amiodarone
Published in:Journal of Cardiovascular Pharmacology
Publication date:1991-06-01
Effects of Ropivacaine on a Potassium Channel (hKv1.5) Cloned from Human Ventricle
Published in:Anesthesiology
Publication date:1997-03-01
Effect of descarboethoxyloratadine, the major metabolite of loratadine, on the human cardiac potassium channel Kv1.5
Published in:British Journal of Pharmacology
Publication date:1997-11-01
Effects of propafenone and 5-hydroxy-propafenone on hKv1.5 channels
Published in:British Journal of Pharmacology
Publication date:1998-11-01
Electrophysiological effects of CI-980, a tubulin binding agent, on guinea-pig papillary muscles
Published in:British Journal of Pharmacology
Publication date:1997-01-01
Effects of rupatadine, a new dual antagonist of histamine and platelet-activating factor receptors, on human cardiac Kv1.5 channels
Published in:British Journal of Pharmacology
Publication date:1999-11-01
Effects of lisinopril on cardiac contractility and ionic currents
Published in:General Pharmacology The Vascular System
Publication date:1994-09-01
Class I and III antiarrhythmic actions of prazosin in guinea-pig papillary muscles
Published in:British Journal of Pharmacology
Publication date:1994-03-01
Effects of lisinopril on electromechanical properties and membrane currents in guinea-pig cardiac preparations
Published in:British Journal of Pharmacology
Publication date:1993-07-01
Electrophysiological effects of E-3753, a new antiarrhythmic drug, in guinea-pig ventricular muscle
Published in:British Journal of Pharmacology
Publication date:1989-04-01
Electrophysiological effects of the combination of mexiletine and flecainide in guinea-pig ventricular fibres
Published in:British Journal of Pharmacology
Publication date:1991-06-01
Kvβ1.3 Reduces the Degree of Stereoselective Bupivacaine Block of Kv1.5 Channels
Published in:Anesthesiology
Publication date:2007-10-01
Pharmacological Consequences of PKC Inhibition on Kv1.5+Kvbeta1.3 Channels
Published in:Biophysical Journal
Publication date:2015-01-01
Effects of levobupivacaine, ropivacaine and bupivacaine onHERGchannels: stereoselective bupivacaine block
Published in:British Journal of Pharmacology
Publication date:2002-12-01
Kv1.5-Kvβ Interactions: Molecular Determinants and Pharmacological Consequences
Published in:Mini-Reviews in Medicinal Chemistry
Publication date:2010-06-01
Electrophysiological Effects of the Combination of Imipramine and Desipramine in Guinea Pig Papillary Muscles
Published in:Journal of Cardiovascular Pharmacology
Publication date:1993-01-01
Pharmacology of CRE-1087, A New Antiarrhythmic Drug
Published in:Cardiovascular Drug Reviews
Publication date:1992-09-01
Electromechanical Effects of Zatebradine on Isolated Guinea Pig Cardiac Preparations
Published in:Journal of Cardiovascular Pharmacology
Publication date:1995-07-01
Electrophysiologic Interactions Between Mexiletine-Quinidine and Mexiletine-Ropitoin in Guinea Pig Papillary Muscle
Published in:Journal of Cardiovascular Pharmacology
Publication date:1989-11-01
Immunomodulation of Voltage-Dependent K+ Channels in Macrophages: Molecular and Biophysical Consequences
Published in:Biophysical Journal
Publication date:2010-01-01
Irvalec Inserts into the Plasma Membrane Causing Rapid Loss of Integrity and Necrotic Cell Death in Tumor Cells
Published in:PLoS ONE
Publication date:2011-04-27
Comparative effects of nonsedating histamine H1 receptor antagonists, ebastine and terfenadine, on human Kv1.5 channels
Published in:European Journal of Pharmacology
Publication date:1997-05-01
Mechanisms of block of a human cloned potassium channel by the enantiomers of a new bradycardic agent: S-16257-2 and S-16260-2
Published in:British Journal of Pharmacology
Publication date:1996-03-01
Effects of the two enantiomers, S-16257-2 and S-16260-2, of a new bradycardic agent on guinea-pig isolated cardiac preparations
Published in:British Journal of Pharmacology
Publication date:1995-07-01
Tonic and frequency-dependent $$\mathop {\text{V}}\limits^{\text{.}} _{{\text{max}}} $$ block induced by (S)-nafenodone, a new antidepressant drug,...
Published in:Naunyn-Schmiedeberg s Archives of Pharmacology
Publication date:1991-06-01
Modulation of the atrial specific Kv1.5 channel by the n-3 polyunsaturated fatty acid, α-linolenic acid
Published in:Journal of Molecular and Cellular Cardiology
Publication date:2008-02-01
Cell cycle-dependent expression of Kv1.5 is involved in myoblast proliferation
Published in:Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
Publication date:2008-05-01
Immunomodulatory effects of diclofenac in leukocytes through the targeting of Kv1.3 voltage-dependent potassium channels
Published in:Biochemical Pharmacology
Publication date:2010-09-01
Celecoxib blocks cardiac Kv1.5, Kv4.3 and Kv7.1 (KCNQ1) channels
Published in:Journal of Molecular and Cellular Cardiology
Publication date:2010-12-01
Celecoxib Blocks Cardiac Kv1.5, Kv4.3 and Kv7.1 (KCNQ1) Channels. Effects on Cardiac Action Potentials
Published in:Biophysical Journal
Publication date:2011-02-01
Irvalec Inserts Into the Plasma Membrane Causing Rapid Loss of Integrity and Necrotic Cell Death in Tumor Cells
Published in:Biophysical Journal
Publication date:2012-01-01
Modulation of Kv and Kir Currents by 15-Epi-Lipoxin-A4 in activated Macrophages. Implications for the Regulation of the Innate Immune Response
Published in:Biophysical Journal
Publication date:2013-01-01
The induction of NOS2 expression by the hybrid cecropin A–melittin antibiotic peptide CA(1–8)M(1–18) in the monocytic line RAW 264.7 is triggered b...
Published in:Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
Publication date:2006-01-01
A newKCNQ1mutation at the S5 segment that impairs its association with KCNE1 is responsible for short QT syndrome
Published in:Cardiovascular Research
Publication date:2015-07-13
Stereoselective Interactions Between Local Anesthetics and Cardiac K+ Channels
Published in:Drug Design Reviews - Online
Publication date:2005-08-01
Functional Assembly of Kv7.1/Kv7.5 Channels With Emerging Properties on Vascular Muscle Physiology
Published in:Arteriosclerosis Thrombosis and Vascular Biology
Publication date:2014-05-22
Ceramide inhibits Kv currents and contributes to TP-receptor-induced vasoconstriction in rat and human pulmonary arteries
Published in:AJP Cell Physiology
Publication date:2011-07-01
439 Rapid effects of Irvalec on tumor cell integrity associated with changes in the ionic membrane conductance
Published in:European Journal of Cancer Supplements
Publication date:2010-11-01
Immunomodulation of voltage-dependent K + channels in macrophages: molecular and biophysical consequences
Published in:The Journal of General Physiology
Publication date:2010-01-25
Ultrafast sodium channel block by dietary fish oil prevents dofetilide-induced ventricular arrhythmias in rabbit hearts
Published in:AJP Heart and Circulatory Physiology
Publication date:2008-07-25
-3 and -6 polyunsaturated fatty acids block HERG channels
Published in:AJP Cell Physiology
Publication date:2005-11-01
Spironolactone and Its Main Metabolite, Canrenoic Acid, Block Human Ether-a-Go-Go-Related Gene Channels
Published in:Circulation
Publication date:2003-02-03
Effects of Irbesartan on Cloned Potassium Channels Involved in Human Cardiac Repolarization
Published in:Journal of Pharmacology and Experimental Therapeutics
Publication date:2003-02-01
Assembly with the Kvbeta 1.3 Subunit Modulates Drug Block of hKv1.5 Channels
Published in:Molecular Pharmacology
Publication date:2002-12-01
Stereoselective effects of the enantiomers of a new local anaesthetic, IQB-9302, on a human cardiac potassium channel (Kv1.5)
Published in:British Journal of Pharmacology
Publication date:2001-01-01
Bupivacaine effects on hKv1.5 channels are dependent on extracellular pH
Published in:British Journal of Pharmacology
Publication date:2001-09-01
Effects of a quaternary bupivacaine derivative on delayed rectifier K+currents
Published in:British Journal of Pharmacology
Publication date:2000-05-01
Activating transcription factor 6 derepression mediates neuroprotection in Huntington disease
Published in:Journal of Clinical Investigation
Publication date:2016-01-11
Elisidepsin Interacts Directly with Glycosylceramides in the Plasma Membrane of Tumor Cells to Induce Necrotic Cell Death
Published in:PLoS ONE
Publication date:2015-10-16
Stereoselective Drug-Channel Interactions
Published in:Stereochemical Aspects of Drug Action and Disposition
Publication date:2003-01-01
D242N, a K V 7.1 LQTS mutation uncovers a key residue for I Ks voltage dependence
Published in:Journal of Molecular and Cellular Cardiology
Publication date:2017-09-01
Fludarabine Inhibits KV1.3 Currents in Human B Lymphocytes
Published in:Frontiers in Pharmacology
Publication date:2017-03-31
In-Depth Study of the Interaction, Sensitivity, and Gating Modulation by PUFAs on K+ Channels; Interaction and New Targets
Published in:Frontiers in Physiology
Publication date:2016-11-24
M-channels and n-3 polyunsaturated fatty acids: role in pain and epilepsy
Published in:Acta Physiologica
Publication date:2016-06-01
Stereoselective block of a human cardiac potassium channel (Kv1.5) by bupivacaine enantiomers
Published in:Biophysical Journal
Publication date:1995-08-01
Gating of cardiac Na+ channels in excised membrane patches after modification by alpha-chymotrypsin
Published in:Biophysical Journal
Publication date:1994-07-01
Effects of 5-hydroxy-propafenone in guinea-pig atrial fibres
Published in:British Journal of Pharmacology
Publication date:1987-03-01
Electrophysiological effects of amoxapine in untreated and in amoxapine-pretreated rat atria
Published in:British Journal of Pharmacology
Publication date:1986-02-01
Negative inotropic effect of somatostatin in guinea-pig atrial fibres
Published in:British Journal of Pharmacology
Publication date:1985-11-01