All Stories

  1. Tuning Mechanism through Buffer Dependence of Hydrogen Evolution Catalyzed by a Cobalt Mini-enzyme

    Article • January 2020, American Chemical Society (ACS)

    Professor Angela Lombardi

  2. Tuning Mechanism through Buffer Dependence of Hydrogen Evolution Catalyzed by a Cobalt Mini-enzyme

    Article • January 2020, American Chemical Society (ACS)

    Professor Angela Lombardi

  3. Engineering Metalloprotein Functions in Designed and Native Scaffolds

    Article • Trends in Biochemical Sciences, July 2019, Elsevier

    Professor Angela Lombardi

  4. De Novo Design of Four-Helix Bundle Metalloproteins: One Scaffold, Diverse Reactivities

    Article • Accounts of Chemical Research, April 2019, American Chemical Society (ACS)

    Professor Angela Lombardi

  5. Mn-Mimochrome VI*a: An Artificial Metalloenzyme With Peroxygenase Activity

    Article • Frontiers in Chemistry, December 2018, Frontiers

    Professor Angela Lombardi

  6. Fluorescent peptide dH3w: A sensor for environmental monitoring of mercury (II)

    Article • PLoS ONE, October 2018, PLOS

    Professor Angela Lombardi

  7. Vincenzo Pavone: Friend, mentor and inspiring scientist

    Article • Biopolymers, October 2018, Wiley

    Professor Angela Lombardi

  8. Artificial Heme Enzymes for the Construction of Gold-Based Biomaterials

    Article • International Journal of Molecular Sciences, September 2018, MDPI AG

    Professor Angela Lombardi

  9. Spectroscopic and metal binding properties of a de novo metalloprotein binding a tetrazinc cluster

    Article • Biopolymers, September 2018, Wiley

    Professor Angela Lombardi

  10. Enhancement of Peroxidase Activity in Artificial Mimochrome VI Catalysts through Rational Design

    Article • ChemBioChem, August 2018, Wiley

    Professor Angela Lombardi

  11. Unveiling the structure of a novel artificial heme-enzyme with peroxidase-like activity: A theoretical investigation

    Article • Biopolymers, August 2018, Wiley

    Professor Angela Lombardi

  12. Enhancement of Peroxidase Activity in Artificial Mimochrome VI Catalysts through Rational Design

    Article • ChemBioChem, July 2018, Wiley

    Professor Angela Lombardi

  13. Exploring the role of unnatural amino acids in antimicrobial peptides

    Article • Scientific Reports, June 2018, Springer Science + Business Media

    Professor Angela Lombardi

  14. Oxidation catalysis by iron and manganese porphyrins within enzyme-like cages

    Article • Biopolymers, February 2018, Wiley

    Professor Angela Lombardi

  15. Direct detection of organophosphate compounds in water by a fluorescence-based biosensing device

    Article • Sensors and Actuators B Chemical, February 2018, Elsevier

    Professor Angela Lombardi

  16. De Novo Design of Tetranuclear Transition Metal Clusters Stabilized by Hydrogen-Bonded Networks in Helical Bundles

    Article • Journal of the American Chemical Society, January 2018, American Chemical Society (ACS)

    Professor Angela Lombardi

  17. Hydrogen evolution from water catalyzed by cobalt-mimochrome VI*a, a synthetic mini-protein

    Article • Chemical Science, January 2018, Royal Society of Chemistry

    Professor Angela Lombardi

  18. A Quartz Crystal Microbalance Immunosensor for Stem Cell Selection and Extraction

    Article • Sensors, November 2017, MDPI AG

    Professor Angela Lombardi

  19. A De Novo Heterodimeric Due Ferri Protein Minimizes the Release of Reactive Intermediates in Dioxygen-Dependent Oxidation

    Article • Angewandte Chemie International Edition, November 2017, Wiley

    Professor Angela Lombardi

  20. A De Novo Heterodimeric Due Ferri Protein Minimizes the Release of Reactive Intermediates in Dioxygen-Dependent Oxidation

    Article • Angewandte Chemie International Edition, November 2017, Wiley

    Professor Angela Lombardi

  21. Identification of novel direct protein-protein interactions by irradiating living cells with femtosecond UV laser pulses

    Article • Biochemical and Biophysical Research Communications, October 2017, Elsevier

    Professor Angela Lombardi

  22. Nano-in-Nano Approach for Enzyme Immobilization Based on Block Copolymers

    Article • ACS Applied Materials & Interfaces, August 2017, American Chemical Society (ACS)

    Professor Angela Lombardi

  23. Novel human bioactive peptides identified in Apolipoprotein B: Evaluation of their therapeutic potential

    Article • Biochemical Pharmacology, April 2017, Elsevier

    Professor Angela Lombardi

  24. Production of human pro-relaxin H2 in the yeast Pichia pastoris

    Article • BMC Biotechnology, January 2017, Springer Science + Business Media

    Professor Angela Lombardi

  25. Inactivation of MSMEG_0412 gene drastically affects surface related properties of Mycobacterium smegmatis

    Article • BMC Microbiology, November 2016, Springer Science + Business Media

    Professor Angela Lombardi

  26. Design and engineering of artificial oxygen-activating metalloenzymes

    Article • Chemical Society Reviews, January 2016, Royal Society of Chemistry

    Professor Angela Lombardi

  27. Designing Covalently Linked Heterodimeric Four-Helix Bundles

    Article • January 2016, Elsevier

    Professor Angela Lombardi

  28. Simple structure, complex function

    Article • Nature Methods, October 2015, Nature

    Professor Angela Lombardi

  29. Femtosecond UV-laser pulses to unveil protein–protein interactions in living cells

    Article • Cellular and Molecular Life Sciences, August 2015, Springer Science + Business Media

    Professor Angela Lombardi

  30. Artificial Diiron Enzymes with a De Novo Designed Four-Helix Bundle Structure

    Article • European Journal of Inorganic Chemistry, July 2015, Wiley

    Professor Angela Lombardi

  31. An artificial heme-enzyme with enhanced catalytic activity: evolution, functional screening and structural characterization

    Article • Organic & Biomolecular Chemistry, January 2015, Royal Society of Chemistry

    Professor Angela Lombardi

  32. Branched porphyrins as functional scaffolds for multisite bioconjugation

    Article • Biotechnology and Applied Biochemistry, September 2014, Wiley

    Professor Angela Lombardi

  33. Crystal structure of an amphiphilic foldamer reveals a 48-mer assembly comprising a hollow truncated octahedron

    Article • Nature Communications, April 2014, Springer Science + Business Media

    Professor Angela Lombardi

  34. Spectroelectrochemistry of FeIII- and CoIII-mimochrome VI artificial enzymes immobilized on mesoporous ITO electrodes

    Article • Chemical Communications, January 2014, Royal Society of Chemistry

    Professor Angela Lombardi

  35. Artificial heme-proteins: determination of axial ligand orientations through paramagnetic NMR shifts

    Article • Chemical Communications, January 2014, Royal Society of Chemistry

    Professor Angela Lombardi, Ricardo Louro

  36. Evaluation of the oligosaccharide composition of commercial follicle stimulating hormone preparations

    Article • Electrophoresis, July 2013, Wiley

    Professor Angela Lombardi

  37. DE NOVODesign of Protein Cages to Accommodate Metal Cofactors

    Article • April 2013, Wiley

    Professor Angela Lombardi

  38. De Novo Design, Synthesis and Characterisation of MP3, A New Catalytic Four-Helix Bundle Hemeprotein

    Article • Chemistry - A European Journal, November 2012, Wiley

    Professor Angela Lombardi

  39. Design and Characterization of a Peptide Mimotope of the HIV-1 gp120 Bridging Sheet

    Article • International Journal of Molecular Sciences, May 2012, MDPI AG

    Professor Angela Lombardi

  40. Structural and Functional Aspects of Metal Binding Sites in Natural and Designed Metalloproteins

    Article • January 2012, Wiley

    Professor Angela Lombardi

  41. A Heme-Peptide Metalloenzyme Mimetic with Natural Peroxidase-Like Activity

    Article • Chemistry - A European Journal, March 2011, Wiley

    Professor Angela Lombardi

  42. Redox and Electrocatalytic Properties of Mimochrome VI, a Synthetic Heme Peptide Adsorbed on Gold

    Article • Langmuir, December 2010, American Chemical Society (ACS)

    Professor Angela Lombardi, PhD Gianantonio Battistuzzi

  43. A FRET-based biosensor for NO detection

    Article • Journal of Inorganic Biochemistry, June 2010, Elsevier

    Professor Angela Lombardi

  44. ChemInform Abstract: Peptide-Based Heme-Protein Models

    Article • ChemInform, May 2010, Wiley

    Professor Angela Lombardi

  45. Spectroscopic and metal-binding properties of DF3: an artificial protein able to accommodate different metal ions

    Article • JBIC Journal of Biological Inorganic Chemistry, March 2010, Springer Science + Business Media

    Professor Angela Lombardi

  46. An artificial di-iron oxo-protein with phenol oxidase activity

    Article • Nature Methods, November 2009, Nature

    Professor Angela Lombardi

  47. Conformation and structure of linear peptides with regularly alternating l- and d-residues: structure of the blocked hexapeptide tert-butyloxycarbonyl-(d-alloisoleucyl-l-isoleucyl)3 methyl ester monohydrate

    Article • International journal of peptide & protein research, January 2009, Wiley

    Professor Angela Lombardi

  48. Conformational versatility of the Nα-acylated tripeptide amide tail of oxytocin

    Article • International journal of peptide & protein research, January 2009, Wiley

    Professor Angela Lombardi

  49. Non coded Cα,α-disubstituted amino acids

    Article • International journal of peptide & protein research, January 2009, Wiley

    Professor Angela Lombardi

  50. Diiron-containing metalloproteins: Developing functional models

    Article • Comptes Rendus Chimie, August 2007, Elsevier

    Professor Angela Lombardi

  51. Response of a Designed Metalloprotein to Changes in Metal Ion Coordination, Exogenous Ligands, and Active Site Volume Determined by X-ray Crystallography

    Article • Journal of the American Chemical Society, December 2005, American Chemical Society (ACS)

    Professor Angela Lombardi

  52. Artificial di-iron proteins: solution characterization of four helix bundles containing two distinct types of inter-helical loops

    Article • JBIC Journal of Biological Inorganic Chemistry, August 2005, Springer Science + Business Media

    Professor Angela Lombardi

  53. Analysis and Design of Turns in α-Helical Hairpins

    Article • Journal of Molecular Biology, March 2005, Elsevier

    Professor Angela Lombardi

  54. Artificial diiron proteins: From structure to function

    Article • Biopolymers, January 2005, Wiley

    Professor Angela Lombardi

  55. Miniaturized heme proteins: crystal structure of Co(III)-mimochrome IV

    Article • JBIC Journal of Biological Inorganic Chemistry, November 2004, Springer Science + Business Media

    Professor Angela Lombardi

  56. Design of a New Mimochrome with Unique Topology

    Article • Chemistry - A European Journal, November 2003, Wiley

    Professor Angela Lombardi

  57. Preorganization of molecular binding sites in designed diiron proteins

    Article • Proceedings of the National Academy of Sciences, March 2003, Proceedings of the National Academy of Sciences

    Professor Angela Lombardi

  58. Conformational and coordination properties of a peptide containing the novel α,α-bis(2-pyridyl)glycine amino acidElectronic supplementary information (ESI) available: Figs. 1S, 2S. See http://www.rsc.org/suppdata/dt/b2/b209199b/

    Article • Dalton Transactions, February 2003, Royal Society of Chemistry

    Professor Angela Lombardi

  59. Sliding Helix and Change of Coordination Geometry in a Model Di-MnII Protein

    Article • Angewandte Chemie International Edition, January 2003, Wiley

    Professor Angela Lombardi

  60. Toward the de Novo Design of a Catalytically Active Helix Bundle:  A Substrate-Accessible Carboxylate-Bridged Dinuclear Metal Center

    Article • Journal of the American Chemical Society, December 2001, American Chemical Society (ACS)

    Professor Angela Lombardi

  61. Peptide-Based Heme−Protein Models

    Article • Chemical Reviews, October 2001, American Chemical Society (ACS)

    Professor Angela Lombardi

  62. ChemInform Abstract: De novo Design of Helical Bundles as Models for Understanding Protein Folding and Function

    Article • ChemInform, February 2001, Wiley

    Professor Angela Lombardi

  63. De Novo Design of Helical Bundles as Models for Understanding Protein Folding and Function

    Article • Accounts of Chemical Research, November 2000, American Chemical Society (ACS)

    Professor Angela Lombardi

  64. Miniaturized metalloproteins: Application to iron–sulfur proteins

    Article • Proceedings of the National Academy of Sciences, October 2000, Proceedings of the National Academy of Sciences

    Professor Angela Lombardi

  65. Retrostructural analysis of metalloproteins: Application to the design of a minimal model for diiron proteins

    Article • Proceedings of the National Academy of Sciences, June 2000, Proceedings of the National Academy of Sciences

    Professor Angela Lombardi

  66. The crystal structure of Afc-containing peptides

    Article • Biopolymers, February 2000, Wiley

    Professor Angela Lombardi

  67. The crystal structure of a Dcp-containing peptide

    Article • Biopolymers, February 2000, Wiley

    Professor Angela Lombardi

  68. Conformational behavior of Cα,α-diphenyl glycine: Extended conformation in tripeptides containing consecutive Dφg residues

    Article • Biopolymers, January 2000, Wiley

    Professor Angela Lombardi

  69. Corrigendum: Tertiary templates for the design of diiron proteins

    Article • Current Opinion in Structural Biology, October 1999, Elsevier

    Professor Angela Lombardi

  70. Tertiary templates for the design of diiron proteins

    Article • Current Opinion in Structural Biology, August 1999, Elsevier

    Professor Angela Lombardi

  71. Crystallization and preliminary X-ray diffraction studies of the carboxylesterase EST2 from Alicyclobacillus acidocaldarius

    Article • Acta Crystallographica Section D Biological Crystallography, July 1999, International Union of Crystallography

    Professor Angela Lombardi

  72. De Novo Design and Structural Characterization of Proteins and Metalloproteins

    Article • Annual Review of Biochemistry, June 1999, Annual Reviews

    Professor Angela Lombardi

  73. From natural to synthetic multisite thrombin inhibitors

    Article • Biopolymers, January 1999, Wiley

    Professor Angela Lombardi

  74. Bicyclic peptides as type I/type II β-turn scaffolds

    Article • Biopolymers, December 1998, Wiley

    Professor Angela Lombardi

  75. Hemoprotein models based on a covalent helix-heme-helix sandwich. 3. Coordination properties, reactivity and catalytic application of Fe(III)- and Fe(II)-mimochrome I

    Article • JBIC Journal of Biological Inorganic Chemistry, December 1998, Springer Science + Business Media

    Professor Angela Lombardi

  76. From synthetic coiled coils to functional proteins: automated design of a receptor for the calmodulin-binding domain of calcineurin

    Article • Journal of Molecular Biology, August 1998, Elsevier

    Dr Giovanna Ghirlanda, Professor Angela Lombardi

  77. Neuronorm is a potent and water soluble neurokinin A receptor antagonist

    Article • Bioorganic & Medicinal Chemistry Letters, July 1998, Elsevier

    Professor Angela Lombardi

  78. Miniaturized hemoproteins: design, synthesis and characterization of mimochrome II

    Article • Inorganica Chimica Acta, July 1998, Elsevier

    Professor Angela Lombardi

  79. A Novel Rigid β-Turn Molecular Scaffold

    Article • Journal of the American Chemical Society, June 1998, American Chemical Society (ACS)

    Professor Angela Lombardi

  80. A novel super-potent neurokinin A receptor antagonist containing dehydroalanine

    Article • Bioorganic & Medicinal Chemistry Letters, May 1998, Elsevier

    Professor Angela Lombardi

  81. Analysis and design of three-stranded coiled coils and three-helix bundles

    Article • Folding and Design, April 1998, Elsevier

    Professor Angela Lombardi

  82. Conformational behaviour of Cα,α-diphenylglycine: foldedvs. extended structures in DφG-containing tripeptides

    Article • Journal of Peptide Science, February 1998, Wiley

    Professor Angela Lombardi

  83. Miniaturized hemoproteins

    Article • Biopolymers, January 1998, Wiley

    Professor Angela Lombardi

  84. Miniaturized hemoproteins

    Article • Biopolymers, January 1998, Wiley

    Professor Angela Lombardi

  85. Design of a Synthetic Receptor for the Calmodulin-Binding Domain of Calcineurin

    Article • Journal of the American Chemical Society, December 1997, American Chemical Society (ACS)

    Dr Giovanna Ghirlanda, Professor Angela Lombardi

  86. A review of the design, synthesis and biological activity of the bicyclic hexapeptide tachykinin NK2 antagonist MEN 10627

    Article • Regulatory Peptides, August 1996, Elsevier

    Professor Angela Lombardi

  87. A Racemic Bicyclic Acylamidine from a Tripeptide Derivative

    Article • Acta Crystallographica Section C Crystal Structure Communications, July 1996, International Union of Crystallography

    Professor Angela Lombardi

  88. Discovering protein secondary structures: Classification and description of isolated α-turns

    Article • Biopolymers, June 1996, Wiley

    Professor Angela Lombardi

  89. Solvent-mediated conformational transition in β-alanine containing cyclic peptides. VIII

    Article • Biopolymers, June 1996, Wiley

    Professor Angela Lombardi

  90. Discovering protein secondary structures: Classification and description of isolated α‐turns

    Article • Biopolymers, June 1996, Wiley

    Professor Angela Lombardi

  91. Unusual conformational preferences of β-alanine containing cyclic peptides. VII

    Article • Biopolymers, June 1996, Wiley

    Professor Angela Lombardi

  92. A Modified Cyclodextrin with a Fully Encapsulated Dansyl Group: Self-Inclusion in the Solid State and in Solution

    Article • Chemistry - A European Journal, April 1996, Wiley

    Professor Angela Lombardi

  93. Solvent‐mediated conformational transition in β‐alanine containing cyclic peptides. VIII

    Article • Biopolymers, February 1996, Wiley

    Professor Angela Lombardi

  94. De novo design of heterotrimeric coiled coils

    Article • Biopolymers, January 1996, Wiley

    Professor Angela Lombardi

  95. De novo design of heterotrimeric coiled coils

    Article • Biopolymers, January 1996, Wiley

    Professor Angela Lombardi

  96. Rational Design of True Hirudin Mimetics:  Synthesis and Characterization of Multisite-Directed α-Thrombin Inhibitors1

    Article • Journal of Medicinal Chemistry, January 1996, American Chemical Society (ACS)

    Professor Angela Lombardi

  97. Conformational rigidity versus flexibility in a novel peptidic neurokinin A receptor antagonist

    Article • Journal of Peptide Science, July 1995, Wiley

    Professor Angela Lombardi

  98. Sodium Bumetanide Trihydrate

    Article • Acta Crystallographica Section C Crystal Structure Communications, March 1995, International Union of Crystallography

    Professor Angela Lombardi

  99. Design and structure of a novel Neurokinin A receptor antagonist cyclo(-Met1-Asp2-Trp3-Phe4-Dap5-Leu6-)cyclo(2β-5β)

    Article • Journal of the Chemical Society Perkin Transactions 2, January 1995, Royal Society of Chemistry

    Professor Angela Lombardi

  100. Design of metal ion binding peptides

    Article • Biopolymers, January 1995, Wiley

    Professor Angela Lombardi

  101. Mixed conformation in C?,?-disubstituted tripeptides: X-ray crystal structures of Z-Aib-Dph-Gly-Ome and Bz-Dph-Dph-Gly-Ome

    Article • Biopolymers, December 1994, Wiley

    Professor Angela Lombardi

  102. A crystal structure with features of an antiparallel ?-pleated sheet

    Article • Biopolymers, November 1994, Wiley

    Professor Angela Lombardi

  103. ?-Alanine containing cyclic peptides with predetermined turned structure. V

    Article • Biopolymers, November 1994, Wiley

    Professor Angela Lombardi

  104. ?-Alanine containing cyclic peptides with turned structure: The?pseudo type II ?-turn.? VI

    Article • Biopolymers, November 1994, Wiley

    Professor Angela Lombardi

  105. Conformational studies on peptides as enzyme inhibitors: chymotrypsin inhibitors using Bowman–Birk type as models

    Article • Journal of the Chemical Society Perkin Transactions 2, January 1994, Royal Society of Chemistry

    Professor Angela Lombardi

  106. A structural two-ring version of a tubular stack of?-rings in crystals of a cyclic D,L-hexapeptide

    Article • Journal of Inclusion Phenomena and Macrocyclic Chemistry, January 1994, Springer Science + Business Media

    Professor Angela Lombardi

  107. Noncoded residues as building blocks in the design of specific secondary structures: Symmetrically disubstituted glycines and ?-alanine

    Article • Biopolymers, July 1993, Wiley

    Professor Angela Lombardi

  108. ?-Alanine containing peptides: ?-Turns in cyclotetrapeptides

    Article • Biopolymers, April 1993, Wiley

    Professor Angela Lombardi

  109. Pt(II) complexes of amino acids and peptides III. X-ray diffraction study of [Cl(Ph3P)Pt(H-Aib-O)]

    Article • Inorganica Chimica Acta, February 1993, Elsevier

    Professor Angela Lombardi

  110. Conformation of diastereomeric peptide sequences: Structural analysis of Z-D-Val-Ac6c-Gly-L-Phe-OMe

    Article • Biopolymers, September 1992, Wiley

    Professor Angela Lombardi

  111. Structural characterization of the .beta.-bend ribbon spiral: crystallographic analysis of two long (L-Pro-Aib)n sequential peptides

    Article • Journal of the American Chemical Society, July 1992, American Chemical Society (ACS)

    Professor Angela Lombardi

  112. Pt(II) complexes of amino acids and peptides II. Structural analysis of trans-[Cl2-Pt-(H-Aib-OH)2n] and trans-[Pt-(H-Aib-O−)2]

    Article • Inorganica Chimica Acta, June 1992, Elsevier

    Professor Angela Lombardi

  113. ?-Alanine containing peptides: A novel molecular tool for the design of ?-turns

    Article • Biopolymers, February 1992, Wiley

    Professor Angela Lombardi

  114. First observation of a helical peptide containing chiral α-monosubstituted residues without a preferred screw sense

    Article • Journal of the Chemical Society Perkin Transactions 2, January 1992, Royal Society of Chemistry

    Professor Angela Lombardi

  115. β-Alanine and β-bends. X-Ray diffraction structures of three linear oligopeptides

    Article • Journal of the Chemical Society Perkin Transactions 2, January 1992, Royal Society of Chemistry

    Professor Angela Lombardi

  116. ?-Alanyl-?-alanine in cyclic ?-turned peptides

    Article • Biopolymers, September 1991, Wiley

    Professor Angela Lombardi

  117. Cyclic ?-alanyl-?-alanine containing peptides: A new molecular tool for ?-turned peptides

    Article • Biopolymers, January 1990, Wiley

    Professor Angela Lombardi

  118. Regularly alternatingL,D-peptides. III. Hexacyclic peptides from valine or phenylalanine

    Article • Biopolymers, January 1989, Wiley

    Professor Angela Lombardi

  119. Pt(II) complexes of amino acids and peptides. I. Structural analysis of trans-[Cl2Pt(L-HAlaOH)2]

    Article • Inorganica Chimica Acta, November 1988, Elsevier

    Professor Angela Lombardi

  120. A novel class of Calmodulin mimetics: De Novo designed proteins in molecular recognition

    Article • Springer Science + Business Media

    Dr Giovanna Ghirlanda, Professor Angela Lombardi

  121. Developing synthetic hemoprotein mimetics: Design, synthesis and characterization of heme-peptide conjugates

    Article • Springer Science + Business Media

    Professor Angela Lombardi